{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:30:47Z","timestamp":1771475447904,"version":"3.50.1"},"reference-count":17,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T00:00:00Z","timestamp":1651795200000},"content-version":"am","delay-in-days":247,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["20FC1034"],"award-info":[{"award-number":["20FC1034"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["brainanddevelopment.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain and Development"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.braindev.2021.04.003","type":"journal-article","created":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T09:42:40Z","timestamp":1620294160000},"page":"867-872","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Mucolipidosis \u2161 and III with neurological symptoms due to spinal cord compression"],"prefix":"10.1016","volume":"43","author":[{"given":"Sachiko","family":"Nakaoka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidehito","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Matsuoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toko","family":"Shibuya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanobu","family":"Otomo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Hamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Ozono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norio","family":"Sakai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.braindev.2021.04.003_b0005","unstructured":"Neufeld EF, Muenzer J. The Mucopolysaccharidoses. The Online Metabolic and Molecular Bases of Inherited Disease. https:\/\/ommbid.mhmedical.com\/content.aspx?sectionid=225544161&bookid=2709."},{"key":"10.1016\/j.braindev.2021.04.003_b0010","unstructured":"Barulke T, Raas-Rothschild A, Kornfeld S. I-cell disease and Pseudo-Hurler polydystrophy: disorders of lysosomal enzyme phosphorylation and localization. The Online Metabolic and Molecular Bases of Inherited Disease. https:\/\/ommbid.mhmedical.com\/content.aspx?bookid=2709&sectionid=225544648."},{"key":"10.1016\/j.braindev.2021.04.003_b0015","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s00381-014-2578-1","article-title":"Spinal involvement in mucopolysaccharidoses: a review","volume":"31","author":"Leone","year":"2015","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.braindev.2021.04.003_b0020","doi-asserted-by":"crossref","first-page":"2538","DOI":"10.1002\/ajmg.a.32294","article-title":"Intrathecal enzyme replacement therapy in a patient with mucopolysaccharidosis type I and symptomatic spinal cord compression","volume":"146A","author":"Munoz-Rojas","year":"2008","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.braindev.2021.04.003_b0025","doi-asserted-by":"crossref","first-page":"20170744","DOI":"10.1259\/bjr.20170744","article-title":"Evaluation of spinal involvement in children with mucopolysaccharidosis VI: the role of MRI","volume":"91","author":"Bulut","year":"2018","journal-title":"Br J Radiol"},{"key":"10.1016\/j.braindev.2021.04.003_b0030","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/ana.1098","article-title":"Brain magnetic resonance imaging in 23 patients with mucopolysaccharidoses and the effect of bone marrow transplantation","volume":"50","author":"Seto","year":"2001","journal-title":"Ann Neurol"},{"key":"10.1016\/j.braindev.2021.04.003_b0035","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0022-510X(96)00301-2","article-title":"Mucolipidosis III(pseudo-Hurler polydystrophy); clinical studies in aged patients in one family","volume":"146","author":"Umehara","year":"1997","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.braindev.2021.04.003_b0040","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/00007632-199116020-00022","article-title":"Atlantoaxial instability and myelopathy in mucolipidosis","volume":"16","author":"Carl","year":"1991","journal-title":"Spine"},{"key":"10.1016\/j.braindev.2021.04.003_b0045","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.ymgme.2006.11.006","article-title":"Lysosomal accumulation of SCMAS (subunit c of mitochondrial ATP synthase) in neurons of the mouse model of mucopolysaccharidosis III B","volume":"90","author":"Ryazantsev","year":"2007","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.braindev.2021.04.003_b0050","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.5664\/jcsm.6362","article-title":"Progression of polysomnographic abnormalities in mucolipidosis II (I-cell disease)","volume":"12","author":"Wooten","year":"2016","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.braindev.2021.04.003_b0055","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1007\/s10545-009-1170-4","article-title":"Sleep-related breathing in children with mucopolysaccharidosis","volume":"32","author":"Nashed","year":"2009","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.braindev.2021.04.003_b0060","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1002\/ppul.21294","article-title":"Isolated central sleep apnea in type I Chiari malformation: improvement after surgery","volume":"45","author":"Spence","year":"2010","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.braindev.2021.04.003_b0065","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/pan.13787","article-title":"Airway management and perioperative adverse events in children with mucopolysaccharidoses and mucolipidoses: a retrospective cohort study","volume":"30","author":"Dohrmann","year":"2020","journal-title":"Paediatr Anaesth"},{"key":"10.1016\/j.braindev.2021.04.003_b0070","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.ymgme.2016.06.001","article-title":"Cervical cord compression in mucopolysaccharidosis VI (MPS VI): findings from the MPS VI clinical surveillance program (CSP)","volume":"118","author":"Solanki","year":"2016","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.braindev.2021.04.003_b0075","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/jhg.2009.3","article-title":"Mucolipidosis II and III alpha\/beta: mutation analysis of 40 Japanese patients showed genotype-phenotype correlation","volume":"54","author":"Otomo","year":"2009","journal-title":"J Hum Genet"},{"issue":"Suppl 2","key":"10.1016\/j.braindev.2021.04.003_b0080","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/s13052-018-0558-x","article-title":"Cerebral and occipito-atlanto-axial involvement in mucopolysaccharidosis patients: clinical, radiological, and neurosurgical features","volume":"44","author":"Giussani","year":"2018","journal-title":"Ital J Pediatr"},{"key":"10.1016\/j.braindev.2021.04.003_b0085","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1159\/000120411","article-title":"Spinal cord injury in I-cell disease","volume":"14","author":"Goodman","year":"1988","journal-title":"Pediatr Neurosci"}],"container-title":["Brain and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760421000681?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760421000681?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T19:49:31Z","timestamp":1759952971000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0387760421000681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S0387760421000681"],"URL":"https:\/\/doi.org\/10.1016\/j.braindev.2021.04.003","relation":{},"ISSN":["0387-7604"],"issn-type":[{"value":"0387-7604","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mucolipidosis \u2161 and III with neurological symptoms due to spinal cord compression","name":"articletitle","label":"Article Title"},{"value":"Brain and Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.braindev.2021.04.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}