{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:01:52Z","timestamp":1781654512147,"version":"3.54.5"},"reference-count":17,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T00:00:00Z","timestamp":1692230400000},"content-version":"am","delay-in-days":320,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["brainanddevelopment.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain and Development"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.braindev.2022.06.004","type":"journal-article","created":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T21:03:02Z","timestamp":1656450182000},"page":"630-634","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Fatal X-linked lymphoproliferative disease type 1-associated limbic encephalitis with positive anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antibody"],"prefix":"10.1016","volume":"44","author":[{"given":"Satoru","family":"Ochiai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itaru","family":"Hayakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eri","family":"Ohashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sho","family":"Hamano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohane","family":"Miyata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Sakuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keita","family":"Hogetsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Gocho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masao","family":"Ogura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Uchiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.braindev.2022.06.004_b0005","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1056\/NEJM197410032911415","article-title":"Letter: Fatal infectious mononucleosis in familial lymphohistiocytosis","volume":"291","author":"Purtilo","year":"1974","journal-title":"N Engl J Med"},{"key":"10.1016\/j.braindev.2022.06.004_b0010","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/S0140-6736(75)92004-8","article-title":"X-linked recessive progressive combined variable immunodeficiency (Duncan\u2019s disease)","volume":"305","author":"Purtilo","year":"1975","journal-title":"Lancet"},{"key":"10.1016\/j.braindev.2022.06.004_b0015","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/2424","article-title":"Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene","volume":"20","author":"Coffey","year":"1998","journal-title":"Nat Genet"},{"key":"10.1016\/j.braindev.2022.06.004_b0020","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1038\/26683","article-title":"The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM","volume":"395","author":"Sayos","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.braindev.2022.06.004_b0025","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jneuroim.2015.06.005","article-title":"A diagnostic approach for identifying anti-neuronal antibodies in children with suspected autoimmune encephalitis","volume":"285","author":"Nakahara","year":"2015","journal-title":"J Neuroimmunol"},{"issue":"6","key":"10.1016\/j.braindev.2022.06.004_b0030","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1002\/pbc.22185","article-title":"Lymphocytic vasculitis involving the central nervous system occurs in patients with X-linked lymphoproliferative disease in the absence of Epstein-Barr virus infection","volume":"53","author":"Talaat","year":"2009","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.braindev.2022.06.004_b0035","doi-asserted-by":"crossref","first-page":"5816","DOI":"10.3390\/ijms22115816","article-title":"Diacylglycerol kinase alpha in X linked lymphoproliferative Disease Type 1","volume":"22","author":"Velnati","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.braindev.2022.06.004_b0040","doi-asserted-by":"crossref","first-page":"666","DOI":"10.3389\/fimmu.2018.00666","article-title":"X-linked lymphoproliferative disease Type 1: A clinical and molecular perspective","volume":"9","author":"Panchal","year":"2018","journal-title":"Front Immunol"},{"issue":"15","key":"10.1016\/j.braindev.2022.06.004_b0045","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1212\/WNL.0b013e31824f800a","article-title":"CNS involvement at the onset of primary hemophagocytic lymphohistiocytosis","volume":"78","author":"Deiva","year":"2012","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.braindev.2022.06.004_b0050","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1212\/01.wnl.0000265597.56202.6c","article-title":"Limbic encephalitis as presentation of a SAP deficiency","volume":"69","author":"Verhelst","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/j.braindev.2022.06.004_b0055","article-title":"Anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis: A review","volume":"12","author":"Zhang","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.braindev.2022.06.004_b0060","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/acn3.43","article-title":"Antigenic and mechanistic characterization of anti-AMPA receptor encephalitis","volume":"1","author":"Gleichman","year":"2014","journal-title":"Ann Clin Transl Neurol"},{"key":"10.1016\/j.braindev.2022.06.004_b0065","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.braindev.2021.07.008","article-title":"Increased cytokines\/chemokines and hyponatremia as a possible cause of clinically mild encephalitis\/encephalopathy with a reversible splenial lesion associated with acute focal bacterial nephritis","volume":"44","author":"Okada","year":"2022","journal-title":"Brain Dev"},{"issue":"03","key":"10.1016\/j.braindev.2022.06.004_b0070","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1055\/s-0039-1687842","article-title":"Central nervous system opportunistic infections","volume":"39","author":"Agnihotri","year":"2019","journal-title":"Semin Neurol"},{"key":"10.1016\/j.braindev.2022.06.004_b0075","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s10875-019-00656-x","article-title":"Diagnostic yield of next generation sequencing in genetically undiagnosed patients with primary immunodeficiencies: a systematic review","volume":"39","author":"Yska","year":"2019","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.braindev.2022.06.004_b0080","doi-asserted-by":"crossref","unstructured":"Raymond LS, Leiding J, Forbes-Satter LR. Diagnostic Modalities in Primary Immunodeficiency. Clin Rev Allergy Immunol 2022, in press. doi: 10.1007\/s12016-022-08933-1.","DOI":"10.1007\/s12016-022-08933-1"},{"key":"10.1016\/j.braindev.2022.06.004_b0085","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1056\/NEJMra1708712","article-title":"Antibody-mediated encephalitis","volume":"378","author":"Dalmau","year":"2018","journal-title":"N Engl J Med"}],"container-title":["Brain and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S038776042200105X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S038776042200105X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T19:50:49Z","timestamp":1759953049000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S038776042200105X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":17,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S038776042200105X"],"URL":"https:\/\/doi.org\/10.1016\/j.braindev.2022.06.004","relation":{},"ISSN":["0387-7604"],"issn-type":[{"value":"0387-7604","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fatal X-linked lymphoproliferative disease type 1-associated limbic encephalitis with positive anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antibody","name":"articletitle","label":"Article Title"},{"value":"Brain and Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.braindev.2022.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Japanese Society of Child Neurology Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}