{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:13:48Z","timestamp":1761128028518},"reference-count":39,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2004,3]]},"DOI":"10.1016\/j.brainres.2003.12.016","type":"journal-article","created":{"date-parts":[[2004,2,4]],"date-time":"2004-02-04T05:13:06Z","timestamp":1075871586000},"page":"35-42","source":"Crossref","is-referenced-by-count":9,"title":["Increased expression of neuronal nitric oxide synthase in bladder afferent cells in the lumbosacral dorsal root ganglia after chronic bladder outflow obstruction"],"prefix":"10.1016","volume":"1002","author":[{"given":"Peter","family":"Zvara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey B","family":"Folsom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"J\u00e1n","family":"Kliment","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbey L","family":"Dattilio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Morav\u010d\u0131\u0301kov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark K","family":"Plante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret A","family":"Vizzard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2003.12.016_BIB1","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1748-1716.1993.tb09578.x","article-title":"Immunohistochemical localization of peripheral nitric oxide synthase-containing nerves using antibodies raised against synthesized C- and N-terminal fragments of a cloned enzyme from rat brain","volume":"148","author":"Alm","year":"1993","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.brainres.2003.12.016_BIB2","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0165-1838(95)00042-7","article-title":"Nitric oxide synthase-immunoreactive, adrenergic, cholinergic, and peptidergic nerves of the female rat urinary tract: a comparative study","volume":"56","author":"Alm","year":"1995","journal-title":"J. Auton. Nerv. Syst."},{"key":"10.1016\/j.brainres.2003.12.016_BIB3","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1016\/S0022-5347(01)67391-9","article-title":"Neural control of urethral outlet activity in vivo: role of nitric oxide","volume":"153","author":"Bennett","year":"1995","journal-title":"J. Urol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB4","first-page":"F226","article-title":"Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder","volume":"275","author":"Birder","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB5","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/S0090-4295(99)80136-8","article-title":"Nitric oxide control of lower genitourinary tract functions: a review","volume":"45","author":"Burnett","year":"1995","journal-title":"Urology"},{"key":"10.1016\/j.brainres.2003.12.016_BIB6","doi-asserted-by":"crossref","first-page":"312","DOI":"10.7326\/0003-4819-92-2-312","article-title":"Physiology of the urinary bladder and urethra","volume":"92","author":"de Groat","year":"1980","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.brainres.2003.12.016_BIB7","series-title":"Proceedings of the Third International Symposium on Brain\u2013Gut Interaction","article-title":"Changes in the primary afferent neurons induced by chronic inflammation or neural injury. Neural control of the urinary bladder and colon","author":"de Groat","year":"1995"},{"key":"10.1016\/j.brainres.2003.12.016_BIB8","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0166-4328(97)00185-X","article-title":"Developmental and injury induced plasticity in the micturition reflex pathway","volume":"92","author":"de Groat","year":"1998","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2003.12.016_BIB9","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/0166-2236(92)90019-5","article-title":"Activity-dependent neuronal plasticity following tissue injury and inflammation","volume":"15","author":"Dubner","year":"1992","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.brainres.2003.12.016_BIB10","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1016\/S0022-5347(05)64371-6","article-title":"Expression of nitric oxide synthase in bladder smooth muscle cells: regulation by cytokines and l-arginine","volume":"168","author":"Johansson","year":"2002","journal-title":"J. Urol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB11","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0022-5347(01)66660-6","article-title":"Role of spinal nitric oxide in the facilitation of the micturition reflex by bladder irritation","volume":"155","author":"Kakizaki","year":"1996","journal-title":"J. Urol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB12","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0022-5347(05)65474-2","article-title":"Contribution of cerebral nitric oxide to bladder overactivity after cerebral infarction in rats","volume":"167","author":"Kodama","year":"2002","journal-title":"J. Urol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB13","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1097\/01.ju.0000085593.31396.d8","article-title":"Involvement of nitric oxide and hyperbaric oxygen in the pathogenesis of cyclophosphamide induced hemorrhagic cystitis in rats","volume":"170","author":"Kormaz","year":"2003","journal-title":"J. Urol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB14","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1002\/(SICI)1097-0029(19990515\/01)45:4\/5<252::AID-JEMT9>3.0.CO;2-N","article-title":"Neurotrophins, nociceptors, and pain","volume":"45","author":"Mendell","year":"1999","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.brainres.2003.12.016_BIB15","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/0306-4522(90)90415-Z","article-title":"Calcitonin gene-related peptide and somatostatin immunoreactivities in the rat lumbar spinal cord: sexually dimorphic aspects","volume":"37","author":"Newton","year":"1990","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2003.12.016_BIB16","series-title":"Society of Neuroscience Annual Meeting","first-page":"388","article-title":"The distribution of PACAP-38-like immunoreactivity in the rat lumbosacral spinal cord differs according to gender and sensitivity to androgen","author":"Newton","year":"1998"},{"key":"10.1016\/j.brainres.2003.12.016_BIB17","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1177\/002215549904700603","article-title":"Morphological and biochemical investigation of nitric oxide synthase and related enzymes in the rat and pig urothelium","volume":"47","author":"Persson","year":"1999","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.brainres.2003.12.016_BIB18","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1152\/jn.2000.83.4.2431","article-title":"Nitric oxide is an autocrine regulator of Na(+) currents in axotomized C-type DRG neurons","volume":"83","author":"Renganathan","year":"2000","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB19","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0304-3940(95)11356-8","article-title":"Topical spinal administration of a nitric oxide synthase inhibitor prevents the hyper-reflexia associated with a rat model of persistent visceral pain","volume":"187","author":"Rice","year":"1995","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2003.12.016_BIB20","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/S0022-5347(17)32614-9","article-title":"Persistence or recurrence of symptoms after transurethral resection of the prostate: a urodynamic assessment","volume":"152","author":"Seaman","year":"1994","journal-title":"J. Urol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB21","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/S0022-5347(17)41846-5","article-title":"Effect of bladder outlet obstruction on micturition reflex pathways in the rat","volume":"140","author":"Steers","year":"1988","journal-title":"J. Urol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB22","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1172\/JCI115488","article-title":"Nerve growth factor in the urinary bladder of the adult regulates neuronal form and function","volume":"88","author":"Steers","year":"1991","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainres.2003.12.016_BIB23","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1159\/000111212","article-title":"Increased expression of neuronal nitric oxide synthase in bladder afferent and spinal neurons following spinal cord injury","volume":"19","author":"Vizzard","year":"1997","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.brainres.2003.12.016_BIB24","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/exnr.1999.7254","article-title":"Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunction","volume":"161","author":"Vizzard","year":"2000","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB25","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/(SICI)1096-9861(20000508)420:3<335::AID-CNE5>3.0.CO;2-#","article-title":"Up-regulation of pituitary adenylate cyclase-activating polypeptide in urinary bladder pathways after chronic cystitis","volume":"420","author":"Vizzard","year":"2000","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB26","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S0006-8993(99)01936-8","article-title":"Increased expression of growth-associated protein (GAP-43) in lower urinary tract pathways following cyclophosphamide (CYP)-induced cystitis","volume":"844","author":"Vizzard","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2003.12.016_BIB27","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0006-8993(94)90090-6","article-title":"Differential distribution of nitric oxide synthase in neural pathways to the urogenital organs (urethra, penis, urinary bladder) of the rat","volume":"646","author":"Vizzard","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2003.12.016_BIB28","doi-asserted-by":"crossref","first-page":"4033","DOI":"10.1523\/JNEUROSCI.15-05-04033.1995","article-title":"Increased expression of neuronal nitric oxide synthase (NOS) in visceral neurons after nerve injury","volume":"15","author":"Vizzard","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2003.12.016_BIB29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0306-4522(95)00137-8","article-title":"Increased expression of neuronal nitric oxide synthase in dorsal root ganglion neurons after systemic capsaicin administration","volume":"67","author":"Vizzard","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2003.12.016_BIB30","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/(SICI)1096-9861(19960624)370:2<191::AID-CNE5>3.0.CO;2-Y","article-title":"Increased expression of neuronal nitric oxide synthase in bladder afferent pathways following chronic bladder irritation","volume":"370","author":"Vizzard","year":"1996","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB31","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s004410050002","article-title":"Transneuronal labeling of neurons in the adult rat central nervous system following inoculation of pseudorabies virus into the colon","volume":"299","author":"Vizzard","year":"2000","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.brainres.2003.12.016_BIB32","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/0306-4522(94)90394-8","article-title":"Neuronal nitric oxide synthase is induced in spinal neurons by traumatic injury","volume":"61","author":"Wu","year":"1994","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2003.12.016_BIB33","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1016\/S0022-5347(05)64261-9","article-title":"Current and future pharmacological treatment for overactive bladder","volume":"168","author":"Yoshimura","year":"2002","journal-title":"J. Urol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB34","doi-asserted-by":"crossref","first-page":"4644","DOI":"10.1523\/JNEUROSCI.19-11-04644.1999","article-title":"Increased excitability of afferent neurons innervating rat urinary bladder after chronic bladder inflammation","volume":"19","author":"Yoshimura","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2003.12.016_BIB35","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/S0306-4522(97)00376-X","article-title":"Effects of spinal cord injury on neurofilament immunoreactivity and capsaicin sensitivity in rat dorsal root ganglion neurons innervating the urinary bladder","volume":"83","author":"Yoshimura","year":"1998","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2003.12.016_BIB36","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1002\/cne.903350408","article-title":"Nitric oxide synthase-like immunoreactivity in lumbar dorsal root ganglia and spinal cord of rat and monkey and effect of peripheral axotomy","volume":"335","author":"Zhang","year":"1993","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2003.12.016_BIB37","first-page":"333","article-title":"Increased NADPH-diaphorase reactivity in bladder afferent pathways following urethral obstruction in guinea pigs","volume":"2","author":"Zhou","year":"1997","journal-title":"J. Peripher. Nerv. Syst."},{"key":"10.1016\/j.brainres.2003.12.016_BIB38","first-page":"209","article-title":"Nitric oxide mediated erectile activity is a testosterone dependent event: a rat erection model","volume":"7","author":"Zvara","year":"1995","journal-title":"Int. J. Impot. Res."},{"key":"10.1016\/j.brainres.2003.12.016_BIB39","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1016\/S0022-5347(05)64244-9","article-title":"Differential expression of bladder neurotrophic factor mRNA in male and female rats after bladder outflow obstruction","volume":"168","author":"Zvara","year":"2002","journal-title":"J. Urol."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899303041830?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899303041830?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T03:21:16Z","timestamp":1550200876000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899303041830"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":39,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["S0006899303041830"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2003.12.016","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}