{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:44:03Z","timestamp":1780105443286,"version":"3.54.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2004,12]]},"DOI":"10.1016\/j.brainres.2004.09.063","type":"journal-article","created":{"date-parts":[[2004,11,9]],"date-time":"2004-11-09T16:54:11Z","timestamp":1100019251000},"page":"57-65","source":"Crossref","is-referenced-by-count":9,"title":["Suppression of excitatory synaptic transmission can facilitate low-calcium epileptiform activity in the hippocampus in vivo"],"prefix":"10.1016","volume":"1030","author":[{"given":"Zhouyan","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique M.","family":"Durand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2004.09.063_bib1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.brainres.2003.11.010","article-title":"Activation of long-term synaptic plasticity causes suppression of epileptiform activity in rat hippocampal slices","volume":"998","author":"Albensi","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2004.09.063_bib2","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1113\/jphysiol.1982.sp014255","article-title":"Feed-forward dendritic inhibition in rat hippocampal pyramidal cells studied in vitro","volume":"328","author":"Alger","year":"1982","journal-title":"J. Physiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib3","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/0006-8993(95)01137-4","article-title":"Differences in the refractory properties of two distinct inhibitory circuitries in field CA1 of the hippocampus","volume":"704","author":"Arai","year":"1995","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2004.09.063_bib4","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1152\/jn.1999.82.5.2262","article-title":"Modulation of burst frequency, duration, and amplitude in the zero-Ca2+ model of epileptiform activity","volume":"82","author":"Bikson","year":"1999","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib5","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0306-4522(89)90398-9","article-title":"Impairment of olfactory memory by local infusions of non-selective excitatory amino acid receptor antagonists into the accessory olfactory bulb","volume":"33","author":"Brennan","year":"1989","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2004.09.063_bib6","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0896-6273(00)81065-X","article-title":"Analysis of relations between NMDA receptors and GABA release at olfactory bulb reciprocal synapses","volume":"25","author":"Chen","year":"2000","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2004.09.063_bib7","series-title":"The NMDA Receptor","first-page":"395","article-title":"The NMDA receptor in epilepsy","author":"Clark","year":"1994"},{"key":"10.1016\/j.brainres.2004.09.063_bib8","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1006\/cbir.1999.0397","article-title":"\u2018Non-synaptic\u2019 mechanisms in seizures and epileptogenesis","volume":"22","author":"Dudek","year":"1998","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.brainres.2004.09.063_bib9","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/00004691-199307000-00004","article-title":"Ictal patterns in experimental models of epilepsy","volume":"10","author":"Durand","year":"1993","journal-title":"J. Clin. Neurophysiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib10","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1152\/jn.00241.2003","article-title":"Low-calcium epileptiform activity in the hippocampus in vivo","volume":"90","author":"Feng","year":"2003","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib11","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1523\/JNEUROSCI.16-06-02034.1996","article-title":"NMDA-dependent modulation of CA1 local circuit inhibition","volume":"16","author":"Grunze","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2004.09.063_bib12","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1523\/JNEUROSCI.06-01-00102.1986","article-title":"N-methyl-d-aspartate receptor antagonists reduce synaptic excitation in the hippocampus","volume":"6","author":"Hablitz","year":"1986","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2004.09.063_bib13","doi-asserted-by":"crossref","first-page":"5124","DOI":"10.1523\/JNEUROSCI.20-13-05124.2000","article-title":"Calcium influx through NMDA receptors directly evokes GABA release in olfactory bulb granule cells","volume":"20","author":"Halabisky","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2004.09.063_bib14","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/S0896-6273(01)00428-7","article-title":"Glutamate-mediated extrasynaptic inhibition: direct coupling of NMDA receptors to Ca2+-activated K+ channels","volume":"31","author":"Isaacson","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2004.09.063_bib15","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1152\/physrev.1995.75.4.689","article-title":"Nonsynaptic modulation of neuronal activity in the brain: electric currents and extracellular ions","volume":"75","author":"Jefferys","year":"1995","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.brainres.2004.09.063_bib16","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/300448a0","article-title":"Synchronized bursting of CA1 hippocampal pyramidal cells in the absence of synaptic of transmission","volume":"300","author":"Jefferys","year":"1982","journal-title":"Nature"},{"key":"10.1016\/j.brainres.2004.09.063_bib17","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1007\/BF00235992","article-title":"Abolition of the orthodromically evoked IPSP of CA1 pyramidal cells before the EPSP during washout of calcium from hippocampal slices","volume":"65","author":"Jones","year":"1987","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.brainres.2004.09.063_bib18","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1152\/jn.2001.86.5.2435","article-title":"Apical and basal orthodromic population spikes in hippocampal CA1 in vivo show different origins and patterns of propagation","volume":"86","author":"Kloosterman","year":"2001","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib19","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/307069a0","article-title":"Slow transmission of neural activity in hippocampal area CA1 in absence of active chemical synapses","volume":"307","author":"Konnerth","year":"1984","journal-title":"Nature"},{"key":"10.1016\/j.brainres.2004.09.063_bib20","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1152\/jn.1987.57.1.325","article-title":"Epileptiform burst activity induced by potassium in the hippocampus and its regulation by GABA-mediated inhibition","volume":"57","author":"Korn","year":"1987","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib21","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1152\/jn.1986.55.6.1268","article-title":"Calcium-dependent current generating the afterhyperpolarization of hippocampal neurons","volume":"55","author":"Lancaster","year":"1986","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib22","doi-asserted-by":"crossref","first-page":"3070","DOI":"10.1523\/JNEUROSCI.22-08-03070.2002","article-title":"NMDA receptor antagonists disinhibit rat posterior cingulate and retrosplenial cortices: a potential mechanism of neurotoxicity","volume":"22","author":"Li","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2004.09.063_bib23","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0028-3908(81)90208-2","article-title":"An electrophysiological model of GABA-mediated neurotransmission","volume":"20","author":"Mattews","year":"1981","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.brainres.2004.09.063_bib24","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1146\/annurev.physiol.63.1.815","article-title":"On the cellular and network bases of epileptic seizures","volume":"63","author":"MCCormick","year":"2001","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib25","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1002\/syn.890020614","article-title":"N-methyl-d-aspartate receptor-mediated component of synaptic responses to single-pulse stimulation in rat hippocampal slices","volume":"2","author":"Muller","year":"1988","journal-title":"Synapse"},{"key":"10.1016\/j.brainres.2004.09.063_bib26","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1126\/science.6262912","article-title":"Synaptic excitation may activate a calcium-dependent potassium conductance in hippocampal pyramidal cells","volume":"212","author":"Nicoll","year":"1981","journal-title":"Science"},{"key":"10.1016\/j.brainres.2004.09.063_bib27","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1126\/science.1835799","article-title":"NMDA antagonist neurotoxicity: mechanism and prevention","volume":"254","author":"Olney","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.brainres.2004.09.063_bib28","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S0166-2236(96)80026-9","article-title":"Ca2+-activated K+ currents in neurones: types, physiological roles and modulation","volume":"19","author":"Sah","year":"1996","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.brainres.2004.09.063_bib29","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/S0896-6273(01)00442-1","article-title":"NMDA receptors turn to another channel for inhibition","volume":"31","author":"Schoppa","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2004.09.063_bib30","doi-asserted-by":"crossref","first-page":"6790","DOI":"10.1523\/JNEUROSCI.18-17-06790.1998","article-title":"Dendrodendritic inhibition in the olfactory bulb is driven by NMDA receptors","volume":"18","author":"Schoppa","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2004.09.063_bib31","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1152\/jn.1992.68.6.2016","article-title":"Prolonged field bursts in the dentate gyrus: dependence on low calcium, high potassium, and nonsynaptic mechanisms","volume":"68","author":"Schweitzer","year":"1992","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib32","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1152\/jn.2002.87.6.2983","article-title":"K+ currents generated by NMDA receptor activation in rat hippocampal pyramidal neurons","volume":"87","author":"Shah","year":"2002","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib33","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1016\/S0006-3495(03)75017-6","article-title":"Ionic mechanisms underlying spontaneous CA1 neuronal firing in Ca2+-free solution","volume":"84","author":"Shuai","year":"2003","journal-title":"Biophys. J."},{"key":"10.1016\/j.brainres.2004.09.063_bib34","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1126\/science.2569762","article-title":"NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model","volume":"245","author":"Stasheff","year":"1989","journal-title":"Science"},{"key":"10.1016\/j.brainres.2004.09.063_bib35","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1126\/science.7134978","article-title":"Synchronous neural afterdischarges in rat hippocampal slices without active chemical synapses","volume":"218","author":"Taylor","year":"1982","journal-title":"Science"},{"key":"10.1016\/j.brainres.2004.09.063_bib36","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1152\/jn.1988.59.1.259","article-title":"Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice","volume":"59","author":"Traynelis","year":"1988","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib37","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1152\/jn.1986.56.2.424","article-title":"Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro: II. Role of extracellular potassium","volume":"56","author":"Yaari","year":"1986","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2004.09.063_bib38","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1046\/j.1528-1157.2002.29001.x","article-title":"Low-frequency electric cortical stimulation has an inhibitory effect on epileptic focus in mesial temporal lobe epilepsy","volume":"43","author":"Yamamoto","year":"2002","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2004.09.063_bib39","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0304-3940(89)90462-X","article-title":"Calcium influx through N-methyl-d-aspartate channels activates a potassium current in postnatal rat hippocampal neurons","volume":"99","author":"Zorumski","year":"1989","journal-title":"Neurosci. Lett."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899304016038?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899304016038?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T17:30:29Z","timestamp":1549647029000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899304016038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["S0006899304016038"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2004.09.063","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2004,12]]}}}