{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T10:52:42Z","timestamp":1762339962553},"reference-count":40,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2005,3]]},"DOI":"10.1016\/j.brainres.2005.01.050","type":"journal-article","created":{"date-parts":[[2005,3,3]],"date-time":"2005-03-03T07:53:44Z","timestamp":1109836424000},"page":"108-115","source":"Crossref","is-referenced-by-count":37,"title":["Nociceptive transmitter release in the dorsal spinal cord by capsaicin-sensitive fibers after noxious gastric stimulation"],"prefix":"10.1016","volume":"1039","author":[{"given":"Rudolf","family":"Schicho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josef","family":"Donnerer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingrid","family":"Liebmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irmgard Th.","family":"Lippe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2005.01.050_bib1","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/cne.20012","article-title":"Vesicular glutamate transporters in the spinal cord, with special reference to sensory primary afferent synapses","volume":"472","author":"Alvarez","year":"2004","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2005.01.050_bib2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0006-8993(96)00661-0","article-title":"Intracolonic zymosan produces visceral hyperalgesia in the rat that is mediated by spinal NMDA and non-NMDA receptors","volume":"736","author":"Coutinho","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2005.01.050_bib3","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1460-9568.2004.03109.x","article-title":"Immunocytochemical characterization of rat brainstem neurons with vagal afferent input from the stomach challenged by acid or ammonia","volume":"19","author":"Danzer","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.brainres.2005.01.050_bib4","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/0006-8993(91)90360-8","article-title":"Depolarization-evoked release of glutamate, aspartate and gamma-aminobutyric acid from rat dorsal spinal cord slices does not originate from capsaicin-sensitive neurons","volume":"555","author":"Donnerer","year":"1991","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2005.01.050_bib5","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0167-0115(92)90061-X","article-title":"Time-course of capsaicin-evoked release of calcitonin gene-related peptide from rat spinal cord in vitro. Effect of concentration and modulation by Ruthenium Red","volume":"37","author":"Donnerer","year":"1992","journal-title":"Regul. Pept."},{"key":"10.1016\/j.brainres.2005.01.050_bib6","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/0306-4522(94)00545-G","article-title":"Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation","volume":"66","author":"Galeazza","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2005.01.050_bib7","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/BF00507224","article-title":"Effect of capsaicin pretreatment on capsaicin-evoked release of immunoreactive somatostatin and substance P from primary sensory neurons","volume":"316","author":"Gamse","year":"1981","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"10.1016\/j.brainres.2005.01.050_bib8","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0304-3940(03)00414-2","article-title":"Role of tachykinin NK1, NK2 and NK3 receptors in the modulation of visceral hypersensitivity in the rat","volume":"351","author":"Gaudreau","year":"2003","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2005.01.050_bib9","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.bbr.2003.07.004","article-title":"Involvement of N-methyl-d-aspartate (NMDA) receptors in a rat model of visceral hypersensitivity","volume":"150","author":"Gaudreau","year":"2004","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2005.01.050_bib10","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0306-4522(88)90017-6","article-title":"Characterization of the peptidergic afferent innervation of the stomach in the rat, mouse and guinea-pig","volume":"25","author":"Green","year":"1988","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2005.01.050_bib11","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1046\/j.1365-2982.2001.00262.x","article-title":"Involvement of spinal calcitonin gene-related peptide in the development of acute visceral hyperalgesia in the rat","volume":"13","author":"Gschossmann","year":"2001","journal-title":"Neurogastroenterol. Motil."},{"key":"10.1016\/j.brainres.2005.01.050_bib12","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/S0016-5085(98)70597-9","article-title":"Neural emergency system in the stomach","volume":"114","author":"Holzer","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.brainres.2005.01.050_bib13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1054\/jpai.2002.27001","article-title":"Activation of lamina I spinal cord neurons that express the substance P receptor in visceral nociception and hyperalgesia","volume":"3","author":"Honore","year":"2002","journal-title":"J. Pain"},{"key":"10.1016\/j.brainres.2005.01.050_bib14","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1152\/jn.2001.86.4.1783","article-title":"Spinal NMDA receptors contribute to neuronal processing of acute noxious and nonnoxious colorectal stimulation in the rat","volume":"86","author":"Ji","year":"2001","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2005.01.050_bib15","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1139\/y97-058","article-title":"Afferent C-fibres release substance P and glutamate","volume":"75","author":"Juranek","year":"1997","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.brainres.2005.01.050_bib16","first-page":"105","article-title":"Combinations of neurokinin receptor antagonists reduce visceral hyperalgesia","volume":"299","author":"Kamp","year":"2001","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.brainres.2005.01.050_bib17","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1152\/jn.1996.75.6.2344","article-title":"Modulation of spinal visceral nociceptive transmission by NMDA receptor activation in the rat","volume":"75","author":"Kolhekar","year":"1996","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2005.01.050_bib18","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.neulet.2003.08.042","article-title":"Neurokinin receptor 1-expressing spinal cord neurons in lamina I and III\/IV of postnatal rats receive inputs from capsaicin sensitive fibers","volume":"352","author":"Labrakakis","year":"2003","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2005.01.050_bib19","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/386721a0","article-title":"NMDA-receptor regulation of substance P release from primary afferent nociceptors","volume":"386","author":"Liu","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.brainres.2005.01.050_bib20","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0016-5085(94)90086-8","article-title":"Basic and clinical aspects of visceral hyperalgesia","volume":"107","author":"Mayer","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1016\/j.brainres.2005.01.050_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0301-0082(98)00048-3","article-title":"The induction of pain: an integrative review","volume":"57","author":"Millan","year":"1999","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.brainres.2005.01.050_bib22","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.ejphar.2004.01.006","article-title":"Role of neuropeptide receptor systems in vanilloid VR1 receptor-mediated gastric acid secretion in rat brain","volume":"486","author":"Minowa","year":"2004","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.brainres.2005.01.050_bib23","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/0306-4522(89)90443-0","article-title":"Release of sensory neuropeptides in the spinal cord: studies with calcitonin gene-related peptide and galanin","volume":"31","author":"Morton","year":"1989","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2005.01.050_bib24","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/BF00318344","article-title":"The central projections of primary afferent neurons of greater splanchnic and intercostal nerves in the rat. A horseradish peroxidase study","volume":"174","author":"Neuhuber","year":"1986","journal-title":"Anat. Embryol. (Berl.)"},{"key":"10.1016\/j.brainres.2005.01.050_bib25","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0304-3959(98)00152-3","article-title":"Differential effects of N-methyl-d-aspartate receptor blockade on nociceptive somatic and visceral reflexes","volume":"79","author":"Olivar","year":"1999","journal-title":"Pain"},{"key":"10.1016\/j.brainres.2005.01.050_bib26","first-page":"G191","article-title":"Calcitonin gene-related peptide in viscerosensitive response to colorectal distension in rats","volume":"273","author":"Plourde","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.brainres.2005.01.050_bib27","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1097\/00001756-199810050-00016","article-title":"Region-specific increase in glutamate release from dorsal horn of rats with adjuvant inflammation","volume":"9","author":"Sasaki","year":"1998","journal-title":"NeuroReport"},{"key":"10.1016\/j.brainres.2005.01.050_bib28","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1046\/j.1365-2982.2003.00384.x","article-title":"Capsaicin-sensitive extrinsic afferents are involved in acid-induced activation of distinct myenteric neurons in the rat stomach","volume":"15","author":"Schicho","year":"2003","journal-title":"Neurogastroenterol. Motil."},{"key":"10.1016\/j.brainres.2005.01.050_bib29","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1111\/j.1460-9568.2004.03290.x","article-title":"Increased expression of TRPV1 receptor in dorsal root ganglia by acid insult of the rat gastric mucosa","volume":"19","author":"Schicho","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.brainres.2005.01.050_bib30","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0016-5085(98)70144-1","article-title":"Gastric acid-evoked c-fos messenger RNA expression in rat brainstem is signaled by capsaicin-resistant vagal afferents","volume":"115","author":"Schuligoi","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.brainres.2005.01.050_bib31","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1523\/JNEUROSCI.23-05-01816.2003","article-title":"Calcitonin gene-related peptide regulates expression of neurokinin1 receptors by rat spinal neurons","volume":"23","author":"Seybold","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2005.01.050_bib32","doi-asserted-by":"crossref","first-page":"2859","DOI":"10.1152\/jn.00339.2004","article-title":"Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization","volume":"92","author":"Sun","year":"2004","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2005.01.050_bib33","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.neuroscience.2003.11.026","article-title":"Evidence of neuronal excitatory amino acid carrier 1 expression in rat dorsal root ganglion neurons and their central terminals","volume":"123","author":"Tao","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2005.01.050_bib34","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0014-2999(96)00052-0","article-title":"Evidence for release of glutamic acid, aspartic acid and substance P but not gamma-aminobutyric acid from primary afferent fibres in rat spinal cord","volume":"302","author":"Teoh","year":"1996","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.brainres.2005.01.050_bib35","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/0301-0082(93)90045-T","article-title":"The localization of classical transmitters and neuropeptides within neurons in laminae I\u2013III of the mammalian spinal dorsal horn","volume":"41","author":"Todd","year":"1993","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.brainres.2005.01.050_bib36","doi-asserted-by":"crossref","first-page":"4103","DOI":"10.1523\/JNEUROSCI.22-10-04103.2002","article-title":"Projection neurons in lamina I of rat spinal cord with the neurokinin 1 receptor are selectively innervated by substance P-containing afferents and respond to noxious stimulation","volume":"22","author":"Todd","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2005.01.050_bib37","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0168-0102(94)90092-2","article-title":"Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: study with on-line continuous monitoring of glutamate","volume":"20","author":"Ueda","year":"1994","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.brainres.2005.01.050_bib38","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1053\/j.gastro.2003.11.047","article-title":"The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methyl-d-aspartate receptor","volume":"126","author":"Willert","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.brainres.2005.01.050_bib39","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0167-0115(99)00046-4","article-title":"Calcitonin gene-related peptide 8\u201337 inhibits the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats","volume":"83","author":"Yu","year":"1999","journal-title":"Regul. Pept."},{"key":"10.1016\/j.brainres.2005.01.050_bib40","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0304-3959(00)00378-X","article-title":"Arthritic calcitonin\/alpha calcitonin gene-related peptide knockout mice have reduced nociceptive hypersensitivity","volume":"89","author":"Zhang","year":"2001","journal-title":"Pain"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899305001216?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899305001216?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T12:32:06Z","timestamp":1549629126000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899305001216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":40,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["S0006899305001216"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2005.01.050","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2005,3]]}}}