{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T22:07:28Z","timestamp":1789510048580,"version":"build-2803163510"},"reference-count":22,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2005,5]]},"DOI":"10.1016\/j.brainres.2005.02.073","type":"journal-article","created":{"date-parts":[[2005,4,11]],"date-time":"2005-04-11T20:03:37Z","timestamp":1113249817000},"page":"155-162","source":"Crossref","is-referenced-by-count":33,"title":["Perfusion and diffusion imaging in acute focal cerebral ischemia: Temporal vs. spatial resolution"],"prefix":"10.1016","volume":"1043","author":[{"given":"Juergen","family":"Bardutzky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Bouley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher H.","family":"Sotak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy Q.","family":"Duong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2005.02.073_bib1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/(SICI)1522-2594(200003)43:3<383::AID-MRM10>3.0.CO;2-Q","article-title":"Functional MRI of calcium-dependent synaptic activity: cross correlation with CBF and BOLD measurements","volume":"43","author":"Duong","year":"2000","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.brainres.2005.02.073_bib2","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1002\/mrm.20087","article-title":"Neuroprotective effects of an immunosuppressant agent on diffusion\/perfusion mismatch in transient focal ischemia","volume":"51","author":"Ebisu","year":"2004","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.brainres.2005.02.073_bib3","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1038\/jcbfm.1995.126","article-title":"Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain: the relationship of quantitative diffusion NMR imaging to reduction in cerebral blood flow and metabolic disturbances","volume":"15","author":"Hoehn-Berlage","year":"1995","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainres.2005.02.073_bib4","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1212\/WNL.57.11.2015","article-title":"Diffusion\u2013perfusion MRI characterization of post-recanalization hyperperfusion in humans","volume":"57","author":"Kidwell","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2005.02.073_bib5","doi-asserted-by":"crossref","first-page":"2729","DOI":"10.1161\/01.STR.0000097608.38779.CC","article-title":"Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging","volume":"34","author":"Kidwell","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2005.02.073_bib6","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1212\/WNL.54.3.689","article-title":"Temporal evolution of ischemic injury evaluated with diffusion-, perfusion-, and T2-weighted MRI","volume":"54","author":"Li","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2005.02.073_bib7","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/ana.10803","article-title":"Characterizing the diffusion\/perfusion mismatch in experimental focal cerebral ischemia","volume":"55","author":"Meng","year":"2004","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2005.02.073_bib8","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.brainresprot.2003.11.004","article-title":"Volumetric evaluation of the ischemic lesion size with serial MRI in a transient MCAO model of the rat: comparison of DWI and T1WI","volume":"12","author":"Nagel","year":"2004","journal-title":"Brain Res. Brain Res. Protoc."},{"key":"10.1016\/j.brainres.2005.02.073_bib9","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1002\/1531-8249(200005)47:5<559::AID-ANA2>3.0.CO;2-S","article-title":"New magnetic resonance imaging methods for cerebrovascular disease: emerging clinical applications","volume":"47","author":"Neumann-Haefelin","year":"2000","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2005.02.073_bib10","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1097\/00004647-200104000-00012","article-title":"Relation of apparent diffusion coefficient changes and metabolic disturbances after 1 hour of focal cerebral ischemia and at different reperfusion phases in rats","volume":"21","author":"Olah","year":"2001","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainres.2005.02.073_bib11","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0014-2999(03)02002-8","article-title":"In vivo neuroprotective effects of ACEA 1021 confirmed by magnetic resonance imaging in ischemic stroke","volume":"474","author":"Petty","year":"2003","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.brainres.2005.02.073_bib12","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1212\/WNL.45.1.172","article-title":"Multislice diffusion mapping for 3-D evolution of cerebral ischemia in a rat stroke model","volume":"45","author":"Reith","year":"1995","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2005.02.073_bib13","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1161\/01.STR.0000030109.12281.23","article-title":"Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke <6 hours","volume":"33","author":"Rother","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2005.02.073_bib14","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1002\/ana.95","article-title":"Stroke magnetic resonance imaging within 6 hours after onset of hyperacute cerebral ischemia","volume":"49","author":"Schellinger","year":"2001","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2005.02.073_bib15","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1212\/WNL.49.1.113","article-title":"Time course of the apparent diffusion coefficient (ADC) abnormality in human stroke","volume":"49","author":"Schlaug","year":"1997","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2005.02.073_bib16","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1212\/WNL.53.7.1528","article-title":"The ischemic penumbra: operationally defined by diffusion and perfusion MRI","volume":"53","author":"Schlaug","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2005.02.073_bib17","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1097\/01.WCB.0000100064.36077.03","article-title":"Pixel-by-pixel spatiotemporal progression of focal ischemia derived using quantitative perfusion and diffusion imaging","volume":"23","author":"Shen","year":"2003","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainres.2005.02.073_bib18","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1097\/00004647-199908000-00006","article-title":"Simultaneous blood oxygenation level-dependent and cerebral blood flow functional magnetic resonance imaging during forepaw stimulation in the rat","volume":"19","author":"Silva","year":"1999","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainres.2005.02.073_bib19","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1063\/1.1695690","article-title":"Spin diffusion measurements: spin echoes in the presence of a time-dependent field gradient","volume":"42","author":"Stejkal","year":"1965","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.brainres.2005.02.073_bib20","doi-asserted-by":"crossref","first-page":"S607","DOI":"10.1016\/S1053-8119(96)80609-4","article-title":"Stimulate: a GUI based fMRI analysis software package","volume":"3","author":"Strupp","year":"1996","journal-title":"NeuroImage"},{"key":"10.1016\/j.brainres.2005.02.073_bib21","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1097\/00004647-199912000-00009","article-title":"Secondary reduction in the apparent diffusion coefficient of water, increase in cerebral blood flow volume, and delayed neuronal death after middle cerebral artery occlusion and reperfusion in the rat","volume":"19","author":"van Lookeren Campagne","year":"1999","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainres.2005.02.073_bib22","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/00004647-200203000-00002","article-title":"Late reversal of cerebral perfusion and water diffusion after transient focal ischemia in rats","volume":"22","author":"Wang","year":"2002","journal-title":"J. Cereb. Blood Flow Metab."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899305003501?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899305003501?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,27]],"date-time":"2019-01-27T12:30:03Z","timestamp":1548592203000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899305003501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":22,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["S0006899305003501"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2005.02.073","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2005,5]]}}}