{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T01:01:58Z","timestamp":1768438918518,"version":"3.49.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2007,4]]},"DOI":"10.1016\/j.brainres.2007.01.094","type":"journal-article","created":{"date-parts":[[2007,2,3]],"date-time":"2007-02-03T07:46:44Z","timestamp":1170488804000},"page":"193-198","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Platelet-activating factor antagonist (ABT-491) decreases neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury"],"prefix":"10.1016","volume":"1143","author":[{"given":"Gulcin","family":"Bozlu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aytug","family":"Atici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Haydar","family":"Turhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayse","family":"Polat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Nayci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cetin","family":"Okuyaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Taskinlar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2007.01.094_bib1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0014-2999(97)00109-X","article-title":"Pharmacology of ABT-491, a highly potent platelet-activating factor receptor antagonist","volume":"325","author":"Albert","year":"1997","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.brainres.2007.01.094_bib2","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S0020-1383(03)00217-1","article-title":"Effects of molsidomine and lexipafant in hepatic ischemia\u2013reperfusion injury","volume":"35","author":"Aldemir","year":"2004","journal-title":"Injury"},{"key":"10.1016\/j.brainres.2007.01.094_bib3","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1194\/jlr.R300013-JLR200","article-title":"Synaptic lipid signaling: significance of polyunsaturated fatty acids and platelet-activating factor","volume":"44","author":"Bazan","year":"2003","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.brainres.2007.01.094_bib4","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.freeradbiomed.2005.08.040","article-title":"Free radicals, mitochondria, and hypoxia\u2013ischemia in developing brain","volume":"40","author":"Blomgren","year":"2006","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.brainres.2007.01.094_bib5","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.prostaglandins.2005.07.001","article-title":"Lipid signaling: sleep, synaptic plasticity, and neuroprotection","volume":"77","author":"Chen","year":"2005","journal-title":"Prostaglandins Other Lipid Mediators"},{"key":"10.1016\/j.brainres.2007.01.094_bib6","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1056\/NEJMra041996","article-title":"Neonatal brain injury","volume":"351","author":"Ferriero","year":"2004","journal-title":"N. Engl. J. Med."},{"issue":"Suppl. 7","key":"10.1016\/j.brainres.2007.01.094_bib7","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1528-1167.2005.00302.x","article-title":"Protecting neurons","volume":"46","author":"Ferriero","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2007.01.094_bib8","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1478-3231.2005.01186.x","article-title":"Effect of platelet-activating factor (PAF) receptor antagonist (BN52021) on acetaminophen-induced acute liver injury and regeneration in rats","volume":"26","author":"Grypioti","year":"2006","journal-title":"Liver Int."},{"key":"10.1016\/j.brainres.2007.01.094_bib9","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.yebeh.2005.05.015","article-title":"Molecular mediators of hypoxic\u2013ischemic injury and implications for epilepsy in the developing brain","volume":"7","author":"Hossain","year":"2005","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.brainres.2007.01.094_bib10","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1203\/00006450-200106000-00003","article-title":"Neurobiology of hypoxic\u2013ischemic injury in the developing brain","volume":"49","author":"Johnston","year":"2001","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.brainres.2007.01.094_bib11","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1093\/cvr\/27.8.1430","article-title":"Role of platelet activating factor in ischaemia\u2013reperfusion injury of isolated rabbit hearts: protective effect of a specific platelet activating factor antagonist, TCV-309","volume":"27","author":"Katoh","year":"1993","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.brainres.2007.01.094_bib12","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1203\/00006450-199612000-00004","article-title":"The platelet-activating factor antagonist BN 52021 attenuates hypoxic\u2013ischemic brain injury in the immature rat","volume":"40","author":"Liu","year":"1996","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.brainres.2007.01.094_bib13","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1203\/00006450-200106000-00016","article-title":"Platelet-activating factor antagonist BN 50730 attenuates hypoxic\u2013ischemic brain injury in neonatal rats","volume":"49","author":"Liu","year":"2001","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.brainres.2007.01.094_bib14","first-page":"267","article-title":"Role of platelet activating factor in cardiac dysfunction, apoptosis and nitric oxide synthase mRNA expression in the ischemic\u2013reperfused rabbit heart","volume":"19","author":"Loucks","year":"2003","journal-title":"Can. J. Cardiol."},{"key":"10.1016\/j.brainres.2007.01.094_bib15","first-page":"340","article-title":"Platelet-activating factor-induced apoptosis is blocked by Bcl-2 in rat intestinal epithelial cells","volume":"286","author":"Lu","year":"2004","journal-title":"Am. J. Physiol.: Gastrointest. Liver Physiol."},{"key":"10.1016\/j.brainres.2007.01.094_bib16","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1073\/pnas.85.3.728","article-title":"Platelet activating factor acetylhydrolase activity in maternal, fetal and newborn rabbit plasma during pregnancy and lactation","volume":"85","author":"Maki","year":"1988","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainres.2007.01.094_bib17","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1034\/j.1600-0676.2002.01552.x","article-title":"Involvement of platelet-activating factor in hepatic apoptosis and necrosis in chronic ethanol-fed rats given endotoxin","volume":"22","author":"Murohisa","year":"2002","journal-title":"Liver"},{"key":"10.1016\/j.brainres.2007.01.094_bib18","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1093\/ilar.47.1.32","article-title":"Brief update on animal models of hypoxic\u2013ischemic encephalopathy and neonatal stroke","volume":"47","author":"Northington","year":"2006","journal-title":"ILAR J."},{"key":"10.1016\/j.brainres.2007.01.094_bib19","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.brainresrev.2005.07.003","article-title":"Apoptosis in perinatal hypoxic\u2013ischemic brain injury: how important is it and should it be inhibited?","volume":"50","author":"Northington","year":"2005","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.brainres.2007.01.094_bib20","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1111\/j.1556-4029.2006.00174.x","article-title":"Cerebral hypoxia and ischemia: the forensic point of view: a review","volume":"51","author":"Oechmichen","year":"2006","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.brainres.2007.01.094_bib21","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.1542\/peds.2005-0620E","article-title":"Summary proceedings from the neurology group on hypoxic\u2013ischemic encephalopathy","volume":"117","author":"Perlman","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.brainres.2007.01.094_bib22","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ana.410090206","article-title":"The influence of immaturity on hypoxic\u2013ischemic brain damage in the rat","volume":"9","author":"Rice","year":"1981","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2007.01.094_bib23","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.freeradbiomed.2005.02.010","article-title":"The role of free radicals in cerebral hypoxia and ischemia","volume":"39","author":"Rodrigo","year":"2005","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.brainres.2007.01.094_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1471-4159.2000.0740001.x","article-title":"Apoptosis and the nervous system","volume":"74","author":"Sastry","year":"2000","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainres.2007.01.094_bib25","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/S1053-2498(99)00039-X","article-title":"Combined treatment with endothelin- and PAF-antagonists reduces posttransplant lung ischemia\/reperfusion injury","volume":"18","author":"Stammberger","year":"1999","journal-title":"J. Heart Lung Transplant."},{"key":"10.1016\/j.brainres.2007.01.094_bib26","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1046\/j.1523-1755.1999.00724.x","article-title":"Long-term protective effect of UR-12670 after warm renal ischemia in uninephrectomized rats","volume":"56","author":"Torras","year":"1999","journal-title":"Kidney Int."},{"key":"10.1016\/j.brainres.2007.01.094_bib28","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1055\/s-2000-9293","article-title":"Hypoxic\u2013ischemic encephalopathy","volume":"17","author":"Vannucci","year":"2000","journal-title":"Am. J. Perinatol."},{"key":"10.1016\/j.brainres.2007.01.094_bib29","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000085978","article-title":"Perinatal hypoxic\u2013ischemic brain damage: evolution of an animal model","volume":"27","author":"Vannucci","year":"2005","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.brainres.2007.01.094_bib30","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1203\/00006450-200007000-00019","article-title":"Reduction of hypoxic\u2013ischemic brain swelling in the neonatal rat with PAF antagonist WEB 2170: lack of long-term protection","volume":"48","author":"Viswanath","year":"2000","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.brainres.2007.01.094_bib27","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1096\/fj.02-0499fje","article-title":"Platelet activating factor promotes mucosal apoptosis via FasL mediating caspase-9 active pathway in rat small intestine after ischemia\u2013reperfusion","volume":"17","author":"Wu","year":"2003","journal-title":"FASEB J."},{"key":"10.1016\/j.brainres.2007.01.094_bib31","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.brainres.2003.10.013","article-title":"Post-ischemic hypothermia-induced tissue protection and diminished apoptosis after neonatal cerebral hypoxia\u2013ischemia","volume":"996","author":"Zhu","year":"2004","journal-title":"Brain Res."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899307001485?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899307001485?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T04:12:42Z","timestamp":1556079162000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899307001485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":31,"alternative-id":["S0006899307001485"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2007.01.094","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2007,4]]}}}