{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T23:12:20Z","timestamp":1790291540874,"version":"4.1.0"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.brainres.2007.02.039","type":"journal-article","created":{"date-parts":[[2007,2,25]],"date-time":"2007-02-25T06:57:35Z","timestamp":1172386655000},"page":"191-199","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Influence of hypoxia and ischemia preconditioning on bilirubin damage to astrocytes"],"prefix":"10.1016","volume":"1149","author":[{"given":"Ana S.","family":"Falc\u00e3o","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui F.M.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adelaide","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria A.","family":"Brito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dora","family":"Brites","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2007.02.039_bib1","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1038\/35094583","article-title":"Cytokines and acute neurodegeneration","volume":"2","author":"Allan","year":"2001","journal-title":"Nat. Rev., Neurosci."},{"key":"10.1016\/j.brainres.2007.02.039_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.anireprosci.2005.01.007","article-title":"Perinatal asphyxia pathophysiology in pig and human: a review","volume":"90","author":"Alonso-Spilsbury","year":"2005","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.brainres.2007.02.039_bib3","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1542\/peds.114.1.297","article-title":"Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation","volume":"114","author":"American Academy of Pediatrics","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.brainres.2007.02.039_bib4","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1006\/exnr.1993.1092","article-title":"Age-dependent sensitivity of cultured rat glial cells to bilirubin toxicity","volume":"121","author":"Amit","year":"1993","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2007.02.039_bib5","first-page":"229","article-title":"Brain damage in preterm infants: etiological pathways","volume":"41","author":"Arpino","year":"2005","journal-title":"Ann. Ist. Super. Sanita"},{"key":"10.1016\/j.brainres.2007.02.039_bib6","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1146\/annurev.immunol.14.1.649","article-title":"The NF-\u03baB and I\u03baB proteins: new discoveries and insights","volume":"14","author":"Baldwin","year":"1996","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.brainres.2007.02.039_bib7","doi-asserted-by":"crossref","first-page":"16093","DOI":"10.1073\/pnas.252626999","article-title":"Biliverdin reductase: a major physiologic cytoprotectant","volume":"99","author":"Bara\u00f1ano","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainres.2007.02.039_bib8","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1542\/peds.114.1.229","article-title":"Research on prevention of bilirubin-induced brain injury and kernicterus: National Institute of Child Health and Human Development conference executive summary. 2003","volume":"114","author":"Blackmon","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.brainres.2007.02.039_bib9","first-page":"254","article-title":"Physiology and pathophysiology of bilirubin metabolism","volume":"vol. 1","author":"Blanckaert","year":"1990"},{"key":"10.1016\/j.brainres.2007.02.039_bib10","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1111\/j.1471-4159.1993.tb03302.x","article-title":"Triiodothyronine is a high-affinity inhibitor of amino acid transport system L1 in cultured astrocytes","volume":"60","author":"Blondeau","year":"1993","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainres.2007.02.039_bib11","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1023\/A:1024111613327","article-title":"Effect of acidosis on bilirubin-induced toxicity to human erythrocytes","volume":"247","author":"Brito","year":"2003","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.brainres.2007.02.039_bib12","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.brainres.2004.07.063","article-title":"A link between hyperbilirubinemia, oxidative stress and injury to neocortical synaptosomes","volume":"1026","author":"Brito","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2007.02.039_bib13","series-title":"New Trends in Brain Research","first-page":"1","article-title":"Cell response to hyperbilirubinemia: a journey along key molecular events","author":"Brito","year":"2006"},{"key":"10.1016\/j.brainres.2007.02.039_bib15","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1179\/016164105X25216","article-title":"Pathophysiology of an hypoxic\u2013ischemic insult during the perinatal period","volume":"27","author":"Calvert","year":"2005","journal-title":"Neurol. Res."},{"key":"10.1016\/j.brainres.2007.02.039_bib17","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0303-7207(93)90221-5","article-title":"Competitive inhibition of thyroid hormone uptake into cultured rat brain astrocytes by bilirubin and bilirubin conjugates","volume":"97","author":"Chantoux","year":"1993","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.brainres.2007.02.039_bib18","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1007\/BF02079073","article-title":"Effects of bilirubin on visual evoked potentials in term infants","volume":"154","author":"Chen","year":"1995","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.brainres.2007.02.039_bib19","first-page":"31","article-title":"An electron microscopic and radioautographic study on experimental kernicterus. I. Bilirubin transport via astroglia","volume":"56","author":"Chen","year":"1969","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.brainres.2007.02.039_bib20","first-page":"45","article-title":"An electron microscopic and radioautographic study on experimental kernicterus. II. Bilirubin movement within neurons and release of waste products via astroglia","volume":"64","author":"Chen","year":"1971","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.brainres.2007.02.039_bib21","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1073\/pnas.96.5.2445","article-title":"Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury","volume":"96","author":"Dor\u00e9","year":"1999","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.brainres.2007.02.039_bib22","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.nbd.2005.03.001","article-title":"Bilirubin-induced inflammatory response, glutamate release, and cell death in rat cortical astrocytes are enhanced in younger cells","volume":"20","author":"Falc\u00e3o","year":"2005","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.brainres.2007.02.039_bib23","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s00401-006-0078-4","article-title":"Bilirubin-induced immunostimulant effects and toxicity vary with neural cell type and maturation state","volume":"112","author":"Falc\u00e3o","year":"2006","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.brainres.2007.02.039_bib24","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.neuroscience.2006.10.026","article-title":"Role of multidrug resistance-associated protein 1 expression in the in vitro susceptibility of rat nerve cell to unconjugated bilirubin","volume":"144","author":"Falc\u00e3o","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2007.02.039_bib25","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1017\/S0022215100081202","article-title":"Neonatal jaundice as a cause of deafness","volume":"89","author":"Fenwick","year":"1975","journal-title":"J. Laryngol. Otol."},{"key":"10.1016\/j.brainres.2007.02.039_bib26","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jneuroim.2004.04.007","article-title":"Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPS","volume":"153","author":"Fernandes","year":"2004","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.brainres.2007.02.039_bib27","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1111\/j.1471-4159.2006.03680.x","article-title":"Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubin","volume":"96","author":"Fernandes","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainres.2007.02.039_bib29","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1159\/000046146","article-title":"Human perinatal asphyxia: correlation of neonatal cytokines with MRI and outcome","volume":"23","author":"Foster-Barber","year":"2001","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.brainres.2007.02.039_bib31","first-page":"173","article-title":"Bilirubin metabolism and kernicterus","volume":"44","author":"Gourley","year":"1997","journal-title":"Adv. Pediatr."},{"key":"10.1016\/j.brainres.2007.02.039_bib32","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1006\/exnr.2000.7518","article-title":"Bilirubin induces apoptosis via activation of NMDA receptors in developing rat brain neurons","volume":"166","author":"Grojean","year":"2000","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2007.02.039_bib33","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1203\/00006450-200104000-00012","article-title":"Bilirubin exerts additional toxic effects in hypoxic cultured neurons from the developing rat brain by the recruitment of glutamate neurotoxicity","volume":"49","author":"Grojean","year":"2001","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.brainres.2007.02.039_bib34","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1053\/sper.2002.37141","article-title":"Combined effects of bilirubin and hypoxia on cultured neurons from the developing rat forebrain","volume":"26","author":"Grojean","year":"2002","journal-title":"Semin. Perinatol."},{"key":"10.1016\/j.brainres.2007.02.039_bib35","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1002\/glia.10161","article-title":"Microglia as a source and target of cytokines","volume":"40","author":"Hanisch","year":"2002","journal-title":"Glia"},{"key":"10.1016\/j.brainres.2007.02.039_bib36","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1203\/01.PDR.0000148711.11519.A5","article-title":"Bilirubin induces apoptosis and necrosis in human NT2-N neurons","volume":"57","author":"Hank\u00f8","year":"2005","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.brainres.2007.02.039_bib37","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1542\/peds.106.2.e15","article-title":"Pioneers in the scientific study of neonatal jaundice and kernicterus","volume":"106","author":"Hansen","year":"2000","journal-title":"Pediatrics"},{"issue":"Suppl 1","key":"10.1016\/j.brainres.2007.02.039_bib38","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1038\/sj.jp.7210634","article-title":"Bilirubin brain toxicity","volume":"21","author":"Hansen","year":"2001","journal-title":"J. Perinatol."},{"key":"10.1016\/j.brainres.2007.02.039_bib39","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1023\/A:1023206906164","article-title":"Apoptosis and activation of Erkl\/2 and Akt in astrocytes postischemia","volume":"28","author":"Jiang","year":"2003","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainres.2007.02.039_bib40","series-title":"Lecture for 38th Meeting of Japanese Society of Child Neurology, Tokyo, Japan, July 1996","first-page":"235","article-title":"Hypoxic and ischemic disorders of infants and children","volume":"vol. 19","author":"Johnston","year":"1997"},{"key":"10.1016\/j.brainres.2007.02.039_bib41","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/j.1750-3639.2005.tb00526.x","article-title":"Excitotoxicity in perinatal brain injury","volume":"15","author":"Johnston","year":"2005","journal-title":"Brain Pathol."},{"key":"10.1016\/j.brainres.2007.02.039_bib42","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1203\/00006450-200106000-00003","article-title":"Neurobiology of hypoxic\u2013ischemic injury in the developing brain","volume":"49","author":"Johnston","year":"2001","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.brainres.2007.02.039_bib43","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.cccn.2005.01.008","article-title":"Understanding severe hyperbilirubinemia and preventing kernicterus: adjuncts in the interpretation of neonatal serum bilirubin","volume":"356","author":"Kaplan","year":"2005","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.brainres.2007.02.039_bib44","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.neuint.2003.11.002","article-title":"Increased release of excitatory amino acids by the actions of ATP and peroxynitrite on volume-regulated anion channels (VRACs) in astrocytes","volume":"45","author":"Kimelberg","year":"2004","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainres.2007.02.039_bib45","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/0006-8993(95)01372-5","article-title":"Glutamate, glutamine and glutamine synthetase in the neonatal rat brain following hypoxia","volume":"707","author":"Krajnc","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2007.02.039_bib46","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1159\/000081969","article-title":"Hyperbilirubinemic serum is cytotoxic and induces apoptosis in murine astrocytes","volume":"87","author":"Kumral","year":"2005","journal-title":"Biol. Neonate"},{"key":"10.1016\/j.brainres.2007.02.039_bib47","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1172\/JCI119846","article-title":"Pathways and mechanisms for cytokine signaling of the central nervous system","volume":"100","author":"Licinio","year":"1997","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainres.2007.02.039_bib48","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1124\/jpet.102.035956","article-title":"Inhibition by naloxone stereoisomers of \u03b2-amyloid peptide (1\u201342)-induced superoxide production in microglia and degeneration of cortical and mesencephalic neurons","volume":"302","author":"Liu","year":"2002","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.brainres.2007.02.039_bib49","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/ana.410420310","article-title":"Hypoxia\u2013ischemia causes abnormalities in glutamate transporters and death of astroglia and neurons in newborn striatum","volume":"42","author":"Martin","year":"1997","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2007.02.039_bib50","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1203\/00006450-198502000-00019","article-title":"Effect of postnatal anoxia on bilirubin levels in rat brain","volume":"19","author":"Mayor","year":"1985","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.brainres.2007.02.039_bib51","first-page":"293","article-title":"Bile pigments: bilatrienes and 5,15-biladienes","volume":"vol. 6","author":"McDonagh","year":"1979"},{"key":"10.1016\/j.brainres.2007.02.039_bib52","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1053\/j.semperi.2004.10.005","article-title":"Mechanisms of hypoxic\u2013ischemic injury in the term infant","volume":"28","author":"McLean","year":"2004","journal-title":"Semin. Perinatol."},{"key":"10.1016\/j.brainres.2007.02.039_bib53","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/S0006-8993(02)03979-3","article-title":"Involvement of protein kinase C in glutamate release from cultured microglia","volume":"962","author":"Nakamura","year":"2003","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2007.02.039_bib54","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/0014-4886(86)90246-3","article-title":"Differential sensitivity of neural cells to bilirubin toxicity","volume":"94","author":"Notter","year":"1986","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2007.02.039_bib55","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/S0166-2236(96)01035-1","article-title":"NF-\u03baB: a crucial transcription factor for glial and neuronal cell function","volume":"20","author":"O'Neill","year":"1997","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.brainres.2007.02.039_bib56","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1046\/j.1365-2362.2003.01261.x","article-title":"New concepts in bilirubin encephalopathy","volume":"33","author":"Ostrow","year":"2003","journal-title":"Eur. J. Clin. Invest."},{"key":"10.1016\/j.brainres.2007.02.039_bib57","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.molmed.2003.12.003","article-title":"Molecular basis of bilirubin-induced neurotoxicity","volume":"10","author":"Ostrow","year":"2004","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.brainres.2007.02.039_bib58","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1542\/peds.72.5.658","article-title":"Auditory nerve\u2013brainstem evoked responses in hyperbilirubinemic neonates","volume":"72","author":"Perlman","year":"1983","journal-title":"Pediatrics"},{"key":"10.1016\/j.brainres.2007.02.039_bib59","first-page":"599","article-title":"Hyperbilirubinemia in the term newborn","volume":"65","author":"Porter","year":"2002","journal-title":"Am. Fam. Phys."},{"key":"10.1016\/j.brainres.2007.02.039_bib60","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1080\/03004430212714","article-title":"Can excess bilirubin levels cause learning difficulties?","volume":"174","author":"Pretorius","year":"2002","journal-title":"Early Child Dev. Care"},{"key":"10.1016\/j.brainres.2007.02.039_bib61","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.molmed.2005.04.008","article-title":"Bilirubin and the risk of common non-hepatic diseases","volume":"11","author":"Rigato","year":"2005","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.brainres.2007.02.039_bib63","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1053\/jhep.2002.32967","article-title":"Bilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neurons","volume":"35","author":"Rodrigues","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.brainres.2007.02.039_bib64","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1523\/JNEUROSCI.1596-03.2004","article-title":"In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE\/ADAM17-tumor necrosis factor-\u03b1 pathway","volume":"24","author":"Romera","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2007.02.039_bib65","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.earlhumdev.2004.06.003","article-title":"Hypoxic\u2013ischemic brain injury in the term infant\u2014Current concepts","volume":"80","author":"Shalak","year":"2004","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.brainres.2007.02.039_bib66","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.pediatrneurol.2003.09.011","article-title":"Bilirubin toxicity in the developing nervous system","volume":"29","author":"Shapiro","year":"2003","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.brainres.2007.02.039_bib67","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1006\/bbrc.1999.1646","article-title":"Inhibition of glutamate uptake by unconjugated bilirubin in cultured cortical rat astrocytes: role of concentration and pH","volume":"265","author":"Silva","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.brainres.2007.02.039_bib68","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S0168-8278(01)00015-0","article-title":"Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid","volume":"34","author":"Silva","year":"2001","journal-title":"J. Hepatol."},{"key":"10.1016\/j.brainres.2007.02.039_bib69","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1203\/00006450-200204000-00022","article-title":"Rat cultured neuronal and glial cells respond differently to toxicity of unconjugated bilirubin","volume":"51","author":"Silva","year":"2002","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.brainres.2007.02.039_bib70","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.toxlet.2005.09.033","article-title":"Dissociated primary nerve cell cultures as models for assessment of neurotoxicity","volume":"163","author":"Silva","year":"2006","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.brainres.2007.02.039_bib71","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1542\/peds.95.4.579","article-title":"Contribution of asphyxia to the induction of hearing impairment in jaundiced Gunn rats","volume":"95","author":"Silver","year":"1995","journal-title":"Pediatrics"},{"key":"10.1016\/j.brainres.2007.02.039_bib72","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S1095-6433(99)00057-4","article-title":"Neonatal tolerance to hypoxia: a comparative-physiological approach","volume":"123","author":"Singer","year":"1999","journal-title":"Comp. Biochem. Physiol., A Mol. Integr. Physiol."},{"key":"10.1016\/j.brainres.2007.02.039_bib73","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0165-5728(01)00402-7","article-title":"Inflammatory gene transcription in human astrocytes exposed to hypoxia: roles of the nuclear factor-\u03baB and autocrine stimulation","volume":"119","author":"Stanimirovic","year":"2001","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.brainres.2007.02.039_bib74","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0304-3940(92)90580-Z","article-title":"Astrocyte glutamate uptake during chemical hypoxia in vitro","volume":"147","author":"Swanson","year":"1992","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2007.02.039_bib75","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2174\/1566524043479185","article-title":"Astrocyte influences on ischemic neuronal death","volume":"4","author":"Swanson","year":"2004","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.brainres.2007.02.039_bib76","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/exnr.2001.7855","article-title":"Perinatal asphyxia induced neuronal loss by apoptosis in the neonatal rat striatum: a combined TUNEL and stereological study","volume":"174","author":"Van de Berg","year":"2002","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2007.02.039_bib77","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1242\/jeb.01064","article-title":"Hypoxia\u2013ischemia in the immature brain","volume":"207","author":"Vannucci","year":"2004","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.brainres.2007.02.039_bib78","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1046\/j.1471-4159.2000.740457.x","article-title":"\u201cInflammatory\u201d cytokines: neuromodulators in normal brain?","volume":"74","author":"Vitkovic","year":"2000","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainres.2007.02.039_bib79","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0165-5728(00)00374-X","article-title":"Resveratrol inhibits interleukin-6 production in cortical mixed glial cells under hypoxia\/hypoglycemia followed by reoxygenation","volume":"112","author":"Wang","year":"2001","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.brainres.2007.02.039_bib80","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0197-0186(99)00145-X","article-title":"Expression of interleukin-1 alpha, tumor necrosis factor alpha and interleukin-6 genes in astrocytes under ischemic injury","volume":"36","author":"Yu","year":"2000","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainres.2007.02.039_bib81","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/glia.1077","article-title":"Ischemia-induced apoptosis in primary cultures of astrocytes","volume":"35","author":"Yu","year":"2001","journal-title":"Glia"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899307004313?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899307004313?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T15:45:52Z","timestamp":1683733552000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899307004313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":76,"alternative-id":["S0006899307004313"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2007.02.039","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}