{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:34:50Z","timestamp":1790742890074,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1016\/j.brainres.2007.06.074","type":"journal-article","created":{"date-parts":[[2007,7,21]],"date-time":"2007-07-21T07:23:30Z","timestamp":1185002610000},"page":"112-123","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":79,"special_numbering":"C","title":["A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice"],"prefix":"10.1016","volume":"1168","author":[{"given":"Shiori","family":"Ogawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Hyuk","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Della","family":"Koovakkattu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis F.","family":"Parada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Sinton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2007.06.074_bib1","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1053\/j.gastro.2006.07.019","article-title":"Glial-derived neurotrophic factor modulates enteric neuronal survival and proliferation through neuropeptide Y","volume":"131","author":"Anitha","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.brainres.2007.06.074_bib2","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/ng782","article-title":"Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte\u2013Duclos disease","volume":"29","author":"Backman","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2007.06.074_bib3","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1046\/j.1523-1747.2000.00877.x","article-title":"Mutation and allelic loss of the PTEN\/MMAC1 gene in primary and metastatic melanoma biopsies","volume":"114","author":"Birck","year":"2000","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.brainres.2007.06.074_bib4","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1053\/hupa.2002.124721","article-title":"Reduced expression of PTEN correlates with breast cancer progression","volume":"33","author":"Bose","year":"2002","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.brainres.2007.06.074_bib5","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1136\/jmg.2004.024646","article-title":"Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations","volume":"42","author":"Butler","year":"2005","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.brainres.2007.06.074_bib6","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0092-8674(00)81973-X","article-title":"Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation","volume":"98","author":"Chemelli","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.brainres.2007.06.074_bib7","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S1044-7431(02)00014-3","article-title":"Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival","volume":"22","author":"Chen","year":"2003","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.074_bib8","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/ajmg.c.30079","article-title":"Current perspectives on the genetic analysis of autism","volume":"142","author":"Coon","year":"2006","journal-title":"Am. J. Med. Genet. C Semin. Med. Genet."},{"key":"10.1016\/j.brainres.2007.06.074_bib9","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1001\/jama.290.3.337","article-title":"Evidence of brain overgrowth in the first year of life in autism","volume":"290","author":"Courchesne","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.brainres.2007.06.074_bib10","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0006-8993(98)01258-X","article-title":"Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests","volume":"835","author":"Crawley","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2007.06.074_bib11","doi-asserted-by":"crossref","first-page":"6897","DOI":"10.1523\/JNEUROSCI.1712-06.2006","article-title":"The developmental neurobiology of autism spectrum disorder","volume":"26","author":"DiCicco-Bloom","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.074_bib12","doi-asserted-by":"crossref","first-page":"7773","DOI":"10.1158\/0008-5472.CAN-04-2487","article-title":"Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo","volume":"64","author":"Fraser","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.brainres.2007.06.074_bib13","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/nrc1072","article-title":"The circadian clock: pacemaker and tumour suppressor","volume":"3","author":"Fu","year":"2003","journal-title":"Nat. Rev., Cancer"},{"key":"10.1016\/j.brainres.2007.06.074_bib14","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.yebeh.2005.08.008","article-title":"Autism and epilepsy: cause, consequence, comorbidity, or coincidence?","volume":"7","author":"Gabis","year":"2005","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.brainres.2007.06.074_bib15","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/S0387-7604(99)00124-2","article-title":"Epilepsy in adolescents and young adults with autistic disorder","volume":"22","author":"Giovanardi Rossi","year":"2000","journal-title":"Brain Dev."},{"key":"10.1016\/j.brainres.2007.06.074_bib16","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1002\/ajmg.1477","article-title":"PTEN mutation in a family with Cowden syndrome and autism","volume":"105","author":"Goffin","year":"2001","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.brainres.2007.06.074_bib17","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1126\/science.1065518","article-title":"Negative regulation of neural stem\/progenitor cell proliferation by the Pten tumor suppressor gene in vivo","volume":"294","author":"Groszer","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.brainres.2007.06.074_bib18","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1086\/342990","article-title":"On the twin risk in autism","volume":"71","author":"Hallmayer","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.brainres.2007.06.074_bib19","doi-asserted-by":"crossref","first-page":"31714","DOI":"10.1074\/jbc.M506225200","article-title":"Ser-557-phosphorylated mCRY2 is degraded upon synergistic phosphorylation by glycogen synthase kinase-3 beta","volume":"280","author":"Harada","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainres.2007.06.074_bib20","first-page":"R1306","article-title":"Behavioral and neurochemical sources of variability of circadian period and phase: studies of circadian rhythms of npy\u2212\/\u2212 mice","volume":"292","author":"Harrington","year":"2007","journal-title":"Am. J. Physiol.: Regul., Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2007.06.074_bib21","doi-asserted-by":"crossref","first-page":"4701","DOI":"10.1523\/JNEUROSCI.5516-05.2006","article-title":"Reelin deficiency and displacement of mature neurons, but not neurogenesis, underlie the formation of granule cell dispersion in the epileptic hippocampus","volume":"26","author":"Heinrich","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.074_bib22","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1023\/A:1021254914276","article-title":"Sleep patterns of children with pervasive developmental disorders","volume":"32","author":"Honomichl","year":"2002","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.brainres.2007.06.074_bib23","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0006-8993(90)91601-C","article-title":"Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy","volume":"535","author":"Houser","year":"1990","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2007.06.074_bib24","doi-asserted-by":"crossref","first-page":"29397","DOI":"10.1074\/jbc.M503526200","article-title":"A role for glycogen synthase kinase-3beta in the mammalian circadian clock","volume":"280","author":"Iitaka","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainres.2007.06.074_bib62","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1111\/j.0953-816X.2004.03322.x","article-title":"Effect of lithium on the circadian rhythms of locomotor activity and glycogen synthase kinase-3 protein expression in the mouse suprachiasmatic nuclei","volume":"19","author":"Iwahana","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.074_bib25","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1038\/ng781","article-title":"Pten regulates neuronal soma size: a mouse model of Lhermitte\u2013Duclos disease","volume":"29","author":"Kwon","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2007.06.074_bib26","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.neuron.2006.03.023","article-title":"Pten regulates neuronal arborization and social interaction in mice","volume":"50","author":"Kwon","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2007.06.074_bib27","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1002\/gene.20197","article-title":"Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations","volume":"44","author":"Kwon","year":"2006","journal-title":"Genesis"},{"key":"10.1016\/j.brainres.2007.06.074_bib28","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1097\/00004583-199702000-00019","article-title":"Macrocephaly in children and adults with autism","volume":"36","author":"Lainhart","year":"1997","journal-title":"J. Am. Acad. Child Adolesc. Psych."},{"key":"10.1016\/j.brainres.2007.06.074_bib29","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1089\/cap.2006.16.737","article-title":"Attention-deficit hyperactivity disorder symptoms in a clinic sample of children and adolescents with pervasive developmental disorders","volume":"16","author":"Lee","year":"2006","journal-title":"J. Child Adolesc. Psychopharmacol."},{"key":"10.1016\/j.brainres.2007.06.074_bib30","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0166-4328(01)00264-9","article-title":"Effects of intergeniculate leaflet lesions on circadian rhythms in the mouse","volume":"128","author":"Lewandowski","year":"2002","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2007.06.074_bib31","series-title":"Pediatric Epilepsy: Diagnosis and Therapy","first-page":"1","article-title":"Pathophysiology of seizures and epilepsy in the mature and immature brain","author":"Lothman","year":"1993"},{"key":"10.1016\/j.brainres.2007.06.074_bib32","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0022-510X(97)00220-7","article-title":"Granule cell dispersion is correlated with early epileptic events in human temporal lobe epilepsy","volume":"154","author":"Lurton","year":"1998","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.brainres.2007.06.074_bib33","doi-asserted-by":"crossref","first-page":"13375","DOI":"10.1074\/jbc.273.22.13375","article-title":"The tumor suppressor, PTEN\/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate","volume":"273","author":"Maehama","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainres.2007.06.074_bib34","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/mrdd.20023","article-title":"Sleep disorders, epilepsy, and autism","volume":"10","author":"Malow","year":"2004","journal-title":"Ment. Retard. Dev. Disabil. Res. Rev."},{"key":"10.1016\/j.brainres.2007.06.074_bib35","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/S0092-8674(01)00383-X","article-title":"A role for the segment polarity gene shaggy\/GSK-3 in the Drosophila circadian clock","volume":"105","author":"Martinek","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.brainres.2007.06.074_bib36","first-page":"R813","article-title":"Behavioral feedback regulation of circadian rhythm phase angle in light\u2013dark entrained mice","volume":"279","author":"Mistlberger","year":"2000","journal-title":"Am. J. Physiol.: Regul., Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2007.06.074_bib37","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/ajmg.c.30081","article-title":"Mouse models of autism spectrum disorders: the challenge for behavioral genetics","volume":"142","author":"Moy","year":"2006","journal-title":"Am. J. Med. Genet. C Semin. Med. Genet."},{"key":"10.1016\/j.brainres.2007.06.074_bib38","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.bbr.2006.07.030","article-title":"Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains","volume":"176","author":"Moy","year":"2007","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2007.06.074_bib39","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1046\/j.1440-1754.1998.00291.x","article-title":"An investigation into sleep characteristics of children with autism and Asperger's disorder","volume":"34","author":"Patzold","year":"1998","journal-title":"J. Paediatr. Child Health"},{"key":"10.1016\/j.brainres.2007.06.074_bib40","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0920-1211(00)00157-1","article-title":"Circadian rhythms: interactions with seizures and epilepsy","volume":"42","author":"Quigg","year":"2000","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.brainres.2007.06.074_bib41","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1146\/annurev.physiol.63.1.647","article-title":"Molecular analysis of mammalian circadian rhythms","volume":"63","author":"Reppert","year":"2001","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.brainres.2007.06.074_bib42","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1034\/j.1601-183X.2003.00037.x","article-title":"Model of autism: increased ratio of excitation\/inhibition in key neural systems","volume":"2","author":"Rubenstein","year":"2003","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.brainres.2007.06.074_bib43","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/hipo.450040302","article-title":"Role of the hippocampus in epilepsy","volume":"4","author":"Schwartzkroin","year":"1994","journal-title":"Hippocampus"},{"key":"10.1016\/j.brainres.2007.06.074_bib44","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1002\/ana.410350604","article-title":"The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy","volume":"35","author":"Sloviter","year":"1994","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2007.06.074_bib45","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1093\/jnci\/93.16.1246","article-title":"PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme","volume":"93","author":"Smith","year":"2001","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.brainres.2007.06.074_bib46","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0092-8674(00)81780-8","article-title":"Negative regulation of PKB\/Akt-dependent cell survival by the tumor suppressor PTEN","volume":"95","author":"Stambolic","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.brainres.2007.06.074_bib49","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.tins.2005.03.007","article-title":"Sleep, epilepsy and thalamic reticular inhibitory neurons","volume":"28","author":"Steriade","year":"2005","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.brainres.2007.06.074_bib47","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1126\/science.8235588","article-title":"Thalamocortical oscillations in the sleeping and aroused brain","volume":"262","author":"Steriade","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.brainres.2007.06.074_bib48","doi-asserted-by":"crossref","first-page":"6425","DOI":"10.1523\/JNEUROSCI.18-16-06425.1998","article-title":"Role of thalamic and cortical neurons in augmenting responses and self-sustained activity: dual intracellular recordings in vivo","volume":"18","author":"Steriade","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.074_bib50","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S1525-5050(03)00006-4","article-title":"Temporal lobe seizures alter the amplitude and timing of rat behavioral rhythms","volume":"4","author":"Stewart","year":"2003","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.brainres.2007.06.074_bib51","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/380639a0","article-title":"Altered circadian activity rhythms and sleep in mice devoid of prion protein","volume":"380","author":"Tobler","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.brainres.2007.06.074_bib52","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1023\/A:1005572128200","article-title":"Treatment of seizure disorders and EEG abnormalities in children with autism spectrum disorders","volume":"30","author":"Tuchman","year":"2000","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.brainres.2007.06.074_bib53","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/S1474-4422(02)00160-6","article-title":"Epilepsy in autism","volume":"1","author":"Tuchman","year":"2002","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.brainres.2007.06.074_bib54","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/19323","article-title":"Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms","volume":"398","author":"van der Horst","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.brainres.2007.06.074_bib55","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1080\/01677060215306","article-title":"Pleiotropic effects of cryptochromes 1 and 2 on free-running and light-entrained murine circadian rhythms","volume":"16","author":"Van Gelder","year":"2002","journal-title":"J. Neurogenet."},{"key":"10.1016\/j.brainres.2007.06.074_bib56","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1086\/340026","article-title":"Protean PTEN: form and function","volume":"70","author":"Waite","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.brainres.2007.06.074_bib57","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1089\/cap.2005.15.477","article-title":"The presentation of anxiety in children with pervasive developmental disorders","volume":"15","author":"Weisbrot","year":"2005","journal-title":"J. Child Adolesc. Psychopharmacol."},{"key":"10.1016\/j.brainres.2007.06.074_bib58","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1161\/01.STR.0000217262.03192.d4","article-title":"Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury","volume":"37","author":"Weise","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2007.06.074_bib59","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1017\/S0012162204000611","article-title":"Sleep patterns and sleep disorders in children with autistic spectrum disorders: insights using parent report and actigraphy","volume":"46","author":"Wiggs","year":"2004","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.brainres.2007.06.074_bib60","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1158\/0008-5472.CAN-05-1986","article-title":"Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner","volume":"66","author":"Yoo","year":"2006","journal-title":"Cancer Res."},{"key":"10.1016\/j.brainres.2007.06.074_bib61","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/(SICI)1096-8628(19981204)80:4<399::AID-AJMG18>3.0.CO;2-O","article-title":"Germline PTEN mutation in a family with Cowden syndrome and Bannayan\u2013Riley\u2013Ruvalcaba syndrome","volume":"80","author":"Zori","year":"1998","journal-title":"Am. J. Med. Genet."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000689930701640X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000689930701640X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T17:36:04Z","timestamp":1757784964000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000689930701640X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":62,"alternative-id":["S000689930701640X"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2007.06.074","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2007.06.074","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}