{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:55:51Z","timestamp":1787792151536,"version":"build-2784847793"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1016\/j.brainres.2007.06.102","type":"journal-article","created":{"date-parts":[[2007,8,11]],"date-time":"2007-08-11T11:09:27Z","timestamp":1186830567000},"page":"83-92","source":"Crossref","is-referenced-by-count":103,"special_numbering":"C","title":["Widespread disruption in brain activation patterns to a working memory task during cocaine abstinence"],"prefix":"10.1016","volume":"1171","author":[{"given":"D.","family":"Tomasi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.Z.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Telang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Maloney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Alia-Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.C.","family":"Caparelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.D.","family":"Volkow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2007.06.102_bib1","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1523\/JNEUROSCI.2097-04.2005","article-title":"Frontal and temporal dopamine release during working memory and attention tasks in healthy humans: a positron emission tomography study using the high-affinity dopamine D2 receptor ligand [11C]FLB 457","volume":"25","author":"Aalto","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.102_bib2","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1176\/appi.ajp.158.3.390","article-title":"Limbic responsiveness to procaine in cocaine-addicted subjects","volume":"158","author":"Adinoff","year":"2001","journal-title":"Am. J. Psych."},{"key":"10.1016\/j.brainres.2007.06.102_bib3","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1176\/appi.ajp.160.10.1892","article-title":"Resting regional cerebral blood flow and gambling task performance in cocaine-dependent subjects and healthy comparison subjects","volume":"160","author":"Adinoff","year":"2003","journal-title":"Am. J. Psych."},{"issue":"6","key":"10.1016\/j.brainres.2007.06.102_bib4","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1038\/sj.npp.1300937","article-title":"Cerebellar vermis involvement in cocaine-related behaviors","volume":"31","author":"Anderson","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainres.2007.06.102_bib5","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/s00213-005-2162-1","article-title":"Effects of chronic cocaine self-administration on norepinephrine transporters in the nonhuman primate brain","volume":"180","author":"Beveridge","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainres.2007.06.102_bib7","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1212\/WNL.54.12.2285","article-title":"Differential effects of cocaine and cocaine alcohol on neurocognitive performance","volume":"54","author":"Bolla","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2007.06.102_bib6","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1176\/jnp.16.4.456","article-title":"Prefrontal cortical dysfunction in abstinent cocaine abusers","volume":"16","author":"Bolla","year":"2004","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.102_bib8","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/S1053-8119(03)00339-2","article-title":"k-space based summary motion detection for functional magnetic resonance imaging","volume":"20","author":"Caparelli","year":"2003","journal-title":"NeuroImage"},{"key":"10.1016\/j.brainres.2007.06.102_bib9","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1093\/brain\/awf052","article-title":"Dopaminergic modulation of high-level cognition in Parkinson's disease: the role of the prefrontal cortex revealed by PET","volume":"125","author":"Cools","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.brainres.2007.06.102_bib10","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nrn755","article-title":"Control of goal-directed and stimulus-driven attention in the brain","volume":"3","author":"Corbetta","year":"2002","journal-title":"Nat. Rev., Neurosci."},{"key":"10.1016\/j.brainres.2007.06.102_bib11","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/ana.20604","article-title":"Cerebellar transcranial magnetic stimulation impairs verbal working memory","volume":"58","author":"Desmond","year":"2005","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2007.06.102_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cne.903250102","article-title":"Topography and collaberalization of the dopaminergic projections to motor and lateral prefrontal cortex in owl monkeys","volume":"325","author":"Gaspar","year":"1992","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2007.06.102_bib13","first-page":"247","article-title":"Acute effects of nicotine withdrawal syndrome in pilots during flight","volume":"74","author":"Giannakoulas","year":"2003","journal-title":"Aviat. Space Environ. Med."},{"key":"10.1016\/j.brainres.2007.06.102_bib14","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0165-0173(99)00045-4","article-title":"D1 receptors in prefrontal cells and circuits","volume":"31","author":"Goldman-Rakic","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2007.06.102_bib15","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1176\/appi.ajp.159.10.1642","article-title":"Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex","volume":"159","author":"Goldstein","year":"2002","journal-title":"Am. J. Psych."},{"key":"10.1016\/j.brainres.2007.06.102_bib16","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/j.neuropsychologia.2004.04.002","article-title":"Severity of neuropsychological impairment in cocaine and alcohol addiction: association with metabolism in the prefrontal cortex","volume":"42","author":"Goldstein","year":"2004","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.brainres.2007.06.102_bib17","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/j.neuroscience.2006.11.024","article-title":"Role of the anterior cingulate and medial orbitofrontal cortex in processing drug cues in cocaine addiction","volume":"144","author":"Goldstein","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2007.06.102_bib18","doi-asserted-by":"crossref","first-page":"3477","DOI":"10.1523\/JNEUROSCI.5129-06.2007","article-title":"Nicotine enhances visuospatial attention by deactivating areas of the resting brain default network","volume":"27","author":"Hahn","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.102_bib19","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/mrm.1153","article-title":"Hyperechoes","volume":"46","author":"Hennig","year":"2001","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.brainres.2007.06.102_bib20","doi-asserted-by":"crossref","first-page":"11017","DOI":"10.1523\/JNEUROSCI.3321-04.2004","article-title":"Executive dysfunction in cocaine addiction: evidence for discordant frontal, cingulate, and cerebellar activity","volume":"24","author":"Hester","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.102_bib21","doi-asserted-by":"crossref","first-page":"7839","DOI":"10.1523\/JNEUROSCI.23-21-07839.2003","article-title":"Cingulate hypoactivity in cocaine users during a GO\u2013NOGO task as revealed by event-related functional magnetic resonance imaging","volume":"23","author":"Kaufman","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.102_bib22","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1097\/01.wnn.0000160823.61201.20","article-title":"Cognitive impairment in acute cocaine withdrawal","volume":"18","author":"Kelley","year":"2005","journal-title":"Cogn. Behav. Neurol."},{"key":"10.1016\/j.brainres.2007.06.102_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/S0006-3223(03)00706-6","article-title":"Platelet abnormalities associated with cerebral perfusion defects in cocaine dependence","volume":"55","author":"Kosten","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainres.2007.06.102_bib24","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.neuroimage.2005.06.039","article-title":"Neural responses to acute cocaine administration in the human brain detected by fMRI","volume":"28","author":"Kufahl","year":"2005","journal-title":"NeuroImage"},{"key":"10.1016\/j.brainres.2007.06.102_bib25","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1002\/mrm.1910340305","article-title":"High contrast and fast three-dimensional magnetic resonance imaging at high fields","volume":"34","author":"Lee","year":"1995","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.brainres.2007.06.102_bib26","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/ana.10078","article-title":"Dopaminergic modulation of cortical function in patients with Parkinson's disease","volume":"51","author":"Mattay","year":"2002","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2007.06.102_bib27","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0301-0082(02)00011-4","article-title":"Dopamine and the regulation of cognition and attention","volume":"67","author":"Nieoullon","year":"2002","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.brainres.2007.06.102_bib28","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1081\/ADA-200068120","article-title":"Cognitive performance by humans during a smoked cocaine binge-abstinence cycle","volume":"31","author":"Pace-Schott","year":"2005","journal-title":"Am. J. Drug Alcohol Abuse"},{"key":"10.1016\/j.brainres.2007.06.102_bib29","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1002\/cne.10596","article-title":"Projections from the paraventricular nucleus of the thalamus to the rat prefrontal cortex and nucleus accumbens shell: ultrastructural characteristics and spatial relationships with dopamine afferents","volume":"459","author":"Pinto","year":"2003","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2007.06.102_bib30","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1073\/pnas.98.2.676","article-title":"A default mode of brain function","volume":"98","author":"Raichle","year":"2001","journal-title":"PNAS"},{"key":"10.1016\/j.brainres.2007.06.102_bib31","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1523\/JNEUROSCI.3038-04.2005","article-title":"Noradrenaline and dopamine elevations in the rat prefrontal cortex in spatial working memory","volume":"25","author":"Rossetti","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.102_bib32","doi-asserted-by":"crossref","first-page":"6076","DOI":"10.1523\/JNEUROSCI.0968-05.2005","article-title":"The primate thalamus is a key target for brain dopamine","volume":"25","author":"Sanchez-Gonzalez","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2007.06.102_bib33","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s00213-004-2004-6","article-title":"Deficits in a sustained attention task following nicotine withdrawal in rats","volume":"178","author":"Shoaib","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainres.2007.06.102_bib34","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/sj.jcbfm.9600314","article-title":"Macrovascular contribution in activation patterns of working memory","volume":"27","author":"Tomasi","year":"2007","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainres.2007.06.102_bib35","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/jmri.10326","article-title":"Echo planar imaging at 4Tesla with minimum acoustic noise","volume":"18","author":"Tomasi","year":"2003","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.brainres.2007.06.102_bib36","doi-asserted-by":"crossref","unstructured":"Tomasi, D., Wang, R., in press. Induced magnetic field gradients and forces in the human head in MRI. J. Magn. Reson. Imaging.","DOI":"10.1002\/jmri.21143"},{"key":"10.1016\/j.brainres.2007.06.102_bib37","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.neuroimage.2005.04.010","article-title":"fMRI-acoustic noise alters brain activation during working memory tasks","volume":"27","author":"Tomasi","year":"2005","journal-title":"NeuroImage"},{"key":"10.1016\/j.brainres.2007.06.102_bib38","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/ana.20766","article-title":"The human inmmunodeficiency virus reduces network capacity: acoustic noise effect","volume":"59","author":"Tomasi","year":"2006","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2007.06.102_bib39","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1002\/hbm.20211","article-title":"Common deactivation patterns during working memory and visual attention tasks: an intra-subject fMRI study at 4 Tesla","volume":"27","author":"Tomasi","year":"2006","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.brainres.2007.06.102_bib40","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.brainres.2006.11.030","article-title":"Different activation patterns for working memory load and visual attention load","volume":"1132","author":"Tomasi","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2007.06.102_bib41","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.pscychresns.2007.03.002","article-title":"Thalamo-cortical dysfunction in cocaine abusers: Implications in attention and perception","volume":"155","author":"Tomasi","year":"2007","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.brainres.2007.06.102_bib42","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1192\/bjp.152.5.641","article-title":"Cerebral blood flow in chronic cocaine users: a study with positron emission tomography","volume":"152","author":"Volkow","year":"1988","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.brainres.2007.06.102_bib43","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1002\/syn.890110303","article-title":"Long-term frontal brain metabolic changes in cocaine abusers","volume":"11","author":"Volkow","year":"1992","journal-title":"Synapse"},{"key":"10.1016\/j.brainres.2007.06.102_bib44","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/syn.890140210","article-title":"Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers","volume":"14","author":"Volkow","year":"1993","journal-title":"Synapse"},{"key":"10.1016\/j.brainres.2007.06.102_bib45","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1176\/ajp.154.1.50","article-title":"Effects of methylphenidate on regional brain glucose metabolism in humans: relationship to dopamine D2 receptors","volume":"154","author":"Volkow","year":"1997","journal-title":"Am. J. Psych."},{"key":"10.1016\/j.brainres.2007.06.102_bib46","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/386830a0","article-title":"Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects","volume":"386","author":"Volkow","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.brainres.2007.06.102_bib47","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1176\/appi.ajp.158.3.377","article-title":"Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers","volume":"158","author":"Volkow","year":"2001","journal-title":"Am. J. Psych."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899307013911?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899307013911?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T17:58:27Z","timestamp":1549648707000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899307013911"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":47,"alternative-id":["S0006899307013911"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2007.06.102","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}