{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T12:00:32Z","timestamp":1761393632798},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1016\/j.brainres.2007.10.055","type":"journal-article","created":{"date-parts":[[2007,11,28]],"date-time":"2007-11-28T07:16:38Z","timestamp":1196234198000},"page":"228-232","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Histological evidence for drug diffusion across the cerebral meninges into the underlying neocortex in rats"],"prefix":"10.1016","volume":"1188","author":[{"given":"Nandor","family":"Ludvig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynette G.","family":"Sheffield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai M.","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirn L.","family":"Baptiste","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orrin","family":"Devinsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben I.","family":"Kuzniecky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2007.10.055_bib1","series-title":"Epilepsy: A Comprehensive Textbook","first-page":"307","article-title":"Neocortical anatomy and physiology","author":"Connors","year":"1997"},{"key":"10.1016\/j.brainres.2007.10.055_bib2","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/0014-4886(76)90021-2","article-title":"Distribution of radioactivity from topically applied [H3] acetylcholine in relation to seizure","volume":"50","author":"Cornblath","year":"1976","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2007.10.055_bib3","first-page":"1","article-title":"The cerebral neocortex. A theory of its operation","volume":"2","author":"Eccles","year":"1984"},{"key":"10.1016\/j.brainres.2007.10.055_bib4","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/j.1528-1157.1997.tb01134.x","article-title":"Local perfusion of diazepam attenuates interictal and ictal events in the bicuculline model of epilepsy in rats","volume":"38","author":"Eder","year":"1997","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2007.10.055_bib5","doi-asserted-by":"crossref","first-page":"3261","DOI":"10.1152\/jn.1998.80.6.3261","article-title":"Contribution of supragranular layers to sensory processing and plasticity in adult rat barrel cortex","volume":"80","author":"Huang","year":"1998","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2007.10.055_bib6","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.eplepsyres.2007.03.014","article-title":"Transmeningeal delivery of GABA to control neocortical seizures in rats","volume":"75","author":"John","year":"2007","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.brainres.2007.10.055_bib7","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1089\/089771502753460259","article-title":"Extradural compression of sensorimotor cortex: a useful model for studies on ischemic brain damage and neuroprotection","volume":"19","author":"Kundrotiene","year":"2002","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2007.10.055_bib8","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/BF00687521","article-title":"Ultrastructure of the outer cortex and the pia mater in man","volume":"28","author":"Lopes","year":"1974","journal-title":"Acta Neuropathol. (Berl.)"},{"key":"10.1016\/j.brainres.2007.10.055_bib9","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/syn.890120202","article-title":"The paradoxical effect of NMDA receptor stimulation on electrical activity of the sensorimotor cortex in freely behaving rats: analysis by combined EEG-intracerebral microdialysis","volume":"12","author":"Ludvig","year":"1992","journal-title":"Synapse"},{"key":"10.1016\/j.brainres.2007.10.055_bib10","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1111\/j.1528-1167.2006.00642.x","article-title":"Epidural pentobarbital delivery can prevent locally induced neocortical seizures in rats: the prospect of transmeningeal pharmacotherapy for intractrable focal epilepsy","volume":"47","author":"Ludvig","year":"2006","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2007.10.055_bib11","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1046\/j.0953-816x.2001.01619.x","article-title":"Inhibition of synaptically evoked cortical acetylcholine release by intracortical glutamate: involvement of GABAergic neurons","volume":"14","author":"Materi","year":"2001","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.brainres.2007.10.055_bib12","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1093\/bja\/54.10.1117","article-title":"Dural permeability to narcotics: in vitro determination and application to extradural administration","volume":"54","author":"Moore","year":"1982","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.brainres.2007.10.055_bib13","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"1998"},{"key":"10.1016\/j.brainres.2007.10.055_bib14","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1002\/ana.20633","article-title":"A common pattern of persistent gene activation in human neocortical epileptic foci","volume":"58","author":"Rakhade","year":"2005","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2007.10.055_bib15","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1083\/jcb.26.2.323","article-title":"Fine structure of the surface of the cerebral cortex of human brain","volume":"26","author":"Ramsey","year":"1965","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.brainres.2007.10.055_bib16","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1126\/science.109922","article-title":"Inhibitory, GABAergic nerve terminals decrease at sites of focal epilepsy","volume":"205","author":"Ribak","year":"1979","journal-title":"Science"},{"key":"10.1016\/j.brainres.2007.10.055_bib17","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/0006-8993(85)90643-2","article-title":"Degeneration of cholinergic neurons in the basal nucleus following kainic acid or N-methyl-d-aspartic acid application to the cerebral cortex in the rat","volume":"339","author":"Sofroniew","year":"1985","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2007.10.055_bib18","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1016\/0306-4522(82)90086-0","article-title":"The axo-axonic interneuron in the cerebral cortex of the rat, cat and monkey","volume":"7","author":"Somogyi","year":"1982","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2007.10.055_bib19","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1002\/ana.410320408","article-title":"The cortical lesion of Huntington's disease: further neurochemical characterization, and reproduction of some of the histological and neurochemical features by N-methyl-d-aspartate lesions of the rat cortex","volume":"32","author":"Storey","year":"1992","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2007.10.055_bib20","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0197-0186(92)90063-W","article-title":"Changes in gamma-aminobutyric acid release induced by topical administration of drugs affecting its metabolism and receptors: studies in freely moving guinea pigs with epidural cups","volume":"21","author":"Tanganelli","year":"1992","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainres.2007.10.055_bib21","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1111\/j.1528-1157.1998.tb01154.x","article-title":"Layer-specific pathways for the horizontal propagation of epileptiform discharges in neocortex","volume":"39","author":"Telfeian","year":"1998","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2007.10.055_bib22","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S1286-0115(05)83235-7","article-title":"Microscopic morphology and histology of the human meninges","volume":"89","author":"Weller","year":"2005","journal-title":"Morphologie"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899307024894?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899307024894?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,5]],"date-time":"2019-05-05T03:51:56Z","timestamp":1557028316000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899307024894"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":22,"alternative-id":["S0006899307024894"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2007.10.055","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}