{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T16:40:53Z","timestamp":1784047253488,"version":"3.55.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1016\/j.brainres.2009.03.010","type":"journal-article","created":{"date-parts":[[2009,3,23]],"date-time":"2009-03-23T10:15:19Z","timestamp":1237803319000},"page":"131-139","source":"Crossref","is-referenced-by-count":40,"special_numbering":"C","title":["Glibenclamide improves neurological function in neonatal hypoxia\u2013ischemia in rats"],"prefix":"10.1016","volume":"1270","author":[{"given":"Yilin","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Fathali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Lekic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiping","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2009.03.010_bib1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1076\/apab.109.2.135.4271","article-title":"Neuroprotective effects of MK 801 and hypothermia used alone and in combination in hypoxic\u2013ischemic brain injury in neonatal rats","volume":"109","author":"Alkan","year":"2001","journal-title":"Arch. Physiol Biochem."},{"key":"10.1016\/j.brainres.2009.03.010_bib2","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1054\/jocn.2001.1031","article-title":"Ischaemic brain oedema","volume":"9","author":"Ayata","year":"2002","journal-title":"J. Clin. Neurosci."},{"key":"10.1016\/j.brainres.2009.03.010_bib3","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.1242\/jeb.01106","article-title":"Protective role of neuronal KATP channels in brain hypoxia","volume":"207","author":"Ballanyi","year":"2004","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.brainres.2009.03.010_bib4","doi-asserted-by":"crossref","first-page":"3449","DOI":"10.1523\/JNEUROSCI.10-10-03449.1990","article-title":"The recovery of forelimb-placing behavior in rats with neonatal unilateral cortical damage involves the remaining hemisphere","volume":"10","author":"Barth","year":"1990","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2009.03.010_bib5","first-page":"301","article-title":"Alterations in cerebral endothelial cell function in ischemia","volume":"71","author":"Betz","year":"1996","journal-title":"Adv. Neurol."},{"key":"10.1016\/j.brainres.2009.03.010_bib6","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1203\/00006450-199711000-00021","article-title":"Sensorimotor function and neuropathology five to six weeks after hypoxia\u2013ischemia in seven-day-old rats","volume":"42","author":"Bona","year":"1997","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.brainres.2009.03.010_bib7","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/1098-1136(200012)32:3<205::AID-GLIA10>3.0.CO;2-6","article-title":"Developmental downregulation of ATP-sensitive potassium conductance in astrocytes in situ","volume":"32","author":"Brockhaus","year":"2000","journal-title":"Glia"},{"key":"10.1016\/j.brainres.2009.03.010_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-8993(02)03094-9","article-title":"Hyperbaric oxygenation prevented brain injury induced by hypoxia\u2013ischemia in a neonatal rat model","volume":"951","author":"Calvert","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.03.010_bib9","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1179\/016164105X25216","article-title":"Pathophysiology of an hypoxic\u2013ischemic insult during the perinatal period","volume":"27","author":"Calvert","year":"2005","journal-title":"Neurol. Res."},{"key":"10.1016\/j.brainres.2009.03.010_bib10","doi-asserted-by":"crossref","first-page":"8568","DOI":"10.1523\/JNEUROSCI.23-24-08568.2003","article-title":"Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain","volume":"23","author":"Chen","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2009.03.010_bib11","doi-asserted-by":"crossref","first-page":"6512","DOI":"10.1523\/JNEUROSCI.21-17-06512.2001","article-title":"Cell swelling and a nonselective cation channel regulated by internal Ca2+ and ATP in native reactive astrocytes from adult rat brain","volume":"21","author":"Chen","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2009.03.010_bib12","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1056\/NEJMra041996","article-title":"Neonatal brain injury","volume":"351","author":"Ferriero","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.brainres.2009.03.010_bib13","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0166-4328(01)00296-0","article-title":"Behavioral tests of hippocampal function: simple paradigms complex problems","volume":"125","author":"Gerlai","year":"2001","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2009.03.010_bib14","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1161\/01.STR.0000074034.32371.13","article-title":"Neurological dysfunctions versus regional infarction volume after focal ischemia in Mongolian gerbils","volume":"34","author":"Ishibashi","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2009.03.010_bib15","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1056\/NEJMoa066224","article-title":"Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy","volume":"355","author":"Kahn","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.brainres.2009.03.010_bib16","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.1161\/STROKEAHA.107.482216","article-title":"Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke","volume":"38","author":"Kunte","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2009.03.010_bib17","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0304-3940(94)90045-0","article-title":"The influence of plasma glucose concentrations on ischemic brain damage is a threshold function","volume":"177","author":"Li","year":"1994","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2009.03.010_bib18","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.brainres.2006.12.023","article-title":"The effect of granulocyte-colony stimulating factor in global cerebral ischemia in rats","volume":"1136","author":"Matchett","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.03.010_bib19","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1161\/01.STR.0000217310.88450.c3","article-title":"Hyperbaric oxygen suppresses NADPH oxidase in a rat subarachnoid hemorrhage model","volume":"37","author":"Ostrowski","year":"2006","journal-title":"Stroke."},{"key":"10.1016\/j.brainres.2009.03.010_bib20","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.clinthera.2006.09.005","article-title":"Intervention strategies for neonatal hypoxic\u2013ischemic cerebral injury","volume":"28","author":"Perlman","year":"2006","journal-title":"Clin. Ther."},{"key":"10.1016\/j.brainres.2009.03.010_bib21","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ana.410090206","article-title":"The influence of immaturity on hypoxic\u2013ischemic brain damage in the rat","volume":"9","author":"Rice","year":"1981","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2009.03.010_bib22","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0033-0620(99)70003-4","article-title":"Ischemic brain edema","volume":"42","author":"Rosenberg","year":"1999","journal-title":"Prog. Cardiovasc. Dis."},{"key":"10.1016\/j.brainres.2009.03.010_bib23","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/nm1390","article-title":"Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke","volume":"12","author":"Simard","year":"2006","journal-title":"Nat. Med."},{"key":"10.1016\/j.brainres.2009.03.010_bib24","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1172\/JCI32041","article-title":"Endothelial sulfonylurea receptor 1-regulated NC Ca-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury","volume":"117","author":"Simard","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainres.2009.03.010_bib25","first-page":"1","article-title":"Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemmorhage","author":"Simard","year":"2008","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainres.2009.03.010_bib26","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/j.neuroscience.2006.10.043","article-title":"Kir6.2-containing ATP-sensitive potassium channels protect cortical neurons from ischemic\/anoxic injury in vitro and in vivo","volume":"144","author":"Sun","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2009.03.010_bib27","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.brainres.2006.07.060","article-title":"Vascular endothelial growth factor improves recovery of sensorimotor and cognitive deficits after focal cerebral ischemia in the rat","volume":"1115","author":"Wang","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.03.010_bib28","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/S0025-6196(11)64847-7","article-title":"Glucose modulation of ischemic brain injury: review and clinical recommendations","volume":"71","author":"Wass","year":"1996","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.brainres.2009.03.010_bib29","first-page":"253","article-title":"Brain edema after intracerebral hemorrhage: the effects of systemic complement depletion","volume":"81","author":"Xi","year":"2002","journal-title":"Acta Neurochir. Suppl."},{"key":"10.1016\/j.brainres.2009.03.010_bib30","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0306-4522(99)00375-9","article-title":"Effect of prolonged O2 deprivation on Na+ channels: differential regulation in adult versus fetal rat brain","volume":"94","author":"Xia","year":"1999","journal-title":"Neuroscience."},{"key":"10.1016\/j.brainres.2009.03.010_bib31","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.yjmcc.2004.11.020","article-title":"Neuroprotection by KATP channels","volume":"38","author":"Yamada","year":"2005","journal-title":"J. Mol. Cell Cardiol."},{"key":"10.1016\/j.brainres.2009.03.010_bib32","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1097\/01.WCB.0000073946.29308.55","article-title":"Inhibition of apoptosis by hyperbaric oxygen in a rat focal cerebral ischemic model","volume":"23","author":"Yin","year":"2003","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainres.2009.03.010_bib33","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1097\/00004647-199810000-00006","article-title":"Evaluation of a motor deficit after chronic focal cerebral ischemia in rats","volume":"18","author":"Yonemori","year":"1998","journal-title":"J. Cereb. Blood Flow Metab."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899309005204?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899309005204?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,18]],"date-time":"2019-05-18T21:11:54Z","timestamp":1558213914000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899309005204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":33,"alternative-id":["S0006899309005204"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2009.03.010","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}