{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:58:34Z","timestamp":1761580714943,"version":"3.37.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["MH-59239"],"award-info":[{"award-number":["MH-59239"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2009,11]]},"DOI":"10.1016\/j.brainres.2009.08.094","type":"journal-article","created":{"date-parts":[[2009,9,10]],"date-time":"2009-09-10T08:40:53Z","timestamp":1252572053000},"page":"44-51","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Non-NMDA receptors in the lateral parabrachial nucleus modulate sodium appetite"],"prefix":"10.1016","volume":"1301","author":[{"given":"Juliana I.F.","family":"De Gobbi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terry G.","family":"Beltz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph F.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Vanderlei","family":"Menani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Thunhorst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan Kim","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2009.08.094_bib1","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1113\/jphysiol.1980.sp013210","article-title":"Increased sodium appetite in the rat induced by intracranial administration of components of the renin-angiotensin system","volume":"301","author":"Avrith","year":"1980","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/j.brainres.2009.08.094_bib2","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/S0022-3565(25)10225-5","article-title":"Dipsogenic effects of excitatory amino acid agonists in pigeons","volume":"264","author":"Baron","year":"1993","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.brainres.2009.08.094_bib3","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/0006-8993(84)90140-9","article-title":"Electrophysiological identification of neurons in the parabrachial nucleus projecting directly to the hypothalamus in the rat","volume":"322","author":"Ciriello","year":"1984","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib4","doi-asserted-by":"crossref","first-page":"R1470","DOI":"10.1152\/ajpregu.1996.271.6.R1470","article-title":"Forebrain angiotensin type 1 receptors and parabrachial serotonin in the control of NaCl and water intake","volume":"271","author":"Colombari","year":"1996","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib5","doi-asserted-by":"crossref","first-page":"R1136","DOI":"10.1152\/ajpregu.00075.2003","article-title":"Corticotropin-releasing hormone in the lateral parabrachial nucleus inhibits sodium appetite in rats","volume":"290","author":"De Castro e Silva","year":"2006","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib6","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0006-8993(00)02784-0","article-title":"Serotonergic mechanisms of the lateral parabrachial nucleus on DOCA-induced sodium intake","volume":"880","author":"De Gobbi","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib7","doi-asserted-by":"crossref","first-page":"R1301","DOI":"10.1152\/ajpregu.2001.280.5.R1301","article-title":"Interaction of serotonin and cholecystokinin in the lateral parabrachial nucleus to control sodium intake","volume":"280","author":"De Gobbi","year":"2001","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2005.04.055","article-title":"Activation of serotonergic 5-HT(1A) receptors in the lateral parabrachial nucleus increases NaCl intake","volume":"1066","author":"De Gobbi","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib9","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/j.neuroscience.2007.03.004","article-title":"5-HT2 and 5-HT3 receptors in the lateral parabrachial nucleus mediate opposite effects on sodium intake","volume":"146","author":"De Gobbi","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2009.08.094_bib10","doi-asserted-by":"crossref","first-page":"R1039","DOI":"10.1152\/ajpregu.1991.261.4.R1039","article-title":"Enhanced drinking after excitotoxic lesions of the parabrachial nucleus in the rat","volume":"261","author":"Edwards","year":"1991","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib11","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1037\/h0092457","article-title":"Forebrain sites of action for drinking and salt appetite to angiotensin or captopril","volume":"103","author":"Fitts","year":"1989","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.brainres.2009.08.094_bib12","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0165-0173(84)90012-2","article-title":"Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat","volume":"319","author":"Fulwiler","year":"1984","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib13","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0006-8993(98)01270-0","article-title":"A subpopulation of neurons in the rat rostral nucleus of the solitary tract that project to the parabrachial nucleus express glutamate-like immunoreactivity","volume":"821","author":"Gill","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib14","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/0031-9384(78)90136-1","article-title":"Hypotension and thirst in rats after isoproterenol treatment","volume":"21","author":"Hosutt","year":"1978","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.brainres.2009.08.094_bib15","doi-asserted-by":"crossref","first-page":"R324","DOI":"10.1152\/ajpregu.1992.263.2.R324","article-title":"Excitatory amino acids may mediate nucleus tractus solitarius input to rat parabrachial neurons","volume":"263","author":"Jhamandas","year":"1992","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib16","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0006-8993(94)91368-4","article-title":"The role of beta1 and beta2 adrenoceptors in isoproterenol-induced drinking","volume":"656","author":"Kirby","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib17","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0361-9230(93)90054-F","article-title":"Efferent projections from the parabrachial nucleus demonstrated with the anterograde tracer Phaseolus vulgaris leucoagglutinin","volume":"30","author":"Krukoff","year":"1993","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.brainres.2009.08.094_bib18","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/0306-4522(85)90281-7","article-title":"A serotonin-containing pathway from the area postrema to the parabrachial nucleus in the rat","volume":"14","author":"Lan\u00e7a","year":"1985","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2009.08.094_bib19","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0197-0186(96)00101-5","article-title":"AMPA receptors modulate extracellular 5-hydroxytryptamine concentration and metabolism in rat striatum in vivo","volume":"30","author":"Maione","year":"1997","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainres.2009.08.094_bib20","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/jnr.10126","article-title":"In vitro evidence that 5-hydroxytryptamine increases efflux of glial glutamate via 5-HT(2A) receptor activation","volume":"67","author":"Meller","year":"2002","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib21","doi-asserted-by":"crossref","first-page":"R1044","DOI":"10.1152\/ajpregu.1995.269.5.R1044","article-title":"Lateral parabrachial serotonergic mechanisms: angiotensin-induced pressor and drinking responses","volume":"269","author":"Menani","year":"1995","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib22","doi-asserted-by":"crossref","first-page":"R1431","DOI":"10.1152\/ajpregu.1998.275.5.R1431","article-title":"Cholecystokinin actions in the parabrachial nucleus: effects on thirst and salt appetite","volume":"275","author":"Menani","year":"1998","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib23","doi-asserted-by":"crossref","first-page":"R162","DOI":"10.1152\/ajpregu.1996.270.1.R162","article-title":"Lateral parabrachial nucleus and serotonergic mechanisms in the control of salt appetite in rats","volume":"270","author":"Menani","year":"1996","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib24","doi-asserted-by":"crossref","first-page":"R555","DOI":"10.1152\/ajpregu.1998.274.2.R555","article-title":"Lateral parabrachial nucleus serotonergic mechanisms and salt appetite induced by sodium depletion","volume":"274","author":"Menani","year":"1998","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib25","doi-asserted-by":"crossref","first-page":"R126","DOI":"10.1152\/ajpregu.2000.279.1.R126","article-title":"Hindbrain serotonin and the rapid induction of sodium appetite","volume":"279","author":"Menani","year":"2000","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib26","doi-asserted-by":"crossref","first-page":"R837","DOI":"10.1152\/ajpregu.00311.2001","article-title":"Serotonergic mechanisms of the lateral parabrachial nucleus and cholinergic-induced sodium appetite","volume":"282","author":"Menani","year":"2002","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib27","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.brainres.2004.09.048","article-title":"Serotonergic mechanism of the lateral parabrachial nucleus and relaxin-induced sodium intake","volume":"1030","author":"Menani","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib28","doi-asserted-by":"crossref","first-page":"R504","DOI":"10.1152\/ajpregu.1986.251.3.R504","article-title":"Lesions in lateral parabrachial nucleus enhance drinking to angiotensin II and isoproterenol","volume":"251","author":"Ohman","year":"1986","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib29","doi-asserted-by":"crossref","first-page":"R264","DOI":"10.1152\/ajpregu.1989.256.1.R264","article-title":"Brain stem mechanisms and the inhibition of angiotensin-induced drinking","volume":"256","author":"Ohman","year":"1989","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib30","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0006-8993(95)00929-K","article-title":"Role of lateral parabrachial nucleus in the inhibition of water intake produced by right atrial stretch","volume":"695","author":"Ohman","year":"1995","journal-title":"Brain Res."},{"year":"1998","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","key":"10.1016\/j.brainres.2009.08.094_bib31"},{"key":"10.1016\/j.brainres.2009.08.094_bib32","doi-asserted-by":"crossref","first-page":"R1631","DOI":"10.1152\/ajpregu.1997.272.5.R1631","article-title":"Glutamate release in parabrachial nucleus and baroreflex alterations after vagal afferent activation","volume":"272","author":"Saleh","year":"1997","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib33","doi-asserted-by":"crossref","first-page":"8846","DOI":"10.1523\/JNEUROSCI.20-23-08846.2000","article-title":"DOI-induced activation of the cortex: dependence on 5-HT2A heteroceptors on thalamocortical glutamatergic neurons","volume":"20","author":"Scruggs","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2009.08.094_bib34","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1038\/sj.bjp.0701656","article-title":"Influence of excitatory amino acids on basal and sensory stimuli-induced release of 5-HT in the locus coeruleus","volume":"123","author":"Singewald","year":"1998","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.brainres.2009.08.094_bib35","doi-asserted-by":"crossref","first-page":"5082","DOI":"10.1210\/endo.140.11.7091","article-title":"Water drinking in rats resulting from intravenous relaxin and its modification by other dipsogenic factors","volume":"140","author":"Sinnayah","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.brainres.2009.08.094_bib36","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.brainresbull.2006.09.017","article-title":"Involvement of NMDA receptor mechanisms in the modulation of serotonin release in the lateral parabrachial nucleus in the rat","volume":"71","author":"Tanaka","year":"2006","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.brainres.2009.08.094_bib37","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1365-2826.1995.tb00743.x","article-title":"The effects of centrally administered porcine relaxin on drinking behaviour in male and female rats","volume":"7","author":"Thornton","year":"1995","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.brainres.2009.08.094_bib38","doi-asserted-by":"crossref","first-page":"R458","DOI":"10.1152\/ajpregu.1994.266.2.R458","article-title":"Renin-angiotensin, arterial blood pressure, and salt appetite in rats","volume":"266","author":"Thunhorst","year":"1994","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.brainres.2009.08.094_bib39","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1126\/science.1978759","article-title":"Glutamate, the dominant excitatory transmitter in neuroendocrine regulation","volume":"250","author":"van den Pol","year":"1990","journal-title":"Science"},{"key":"10.1016\/j.brainres.2009.08.094_bib40","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0006-8993(97)01186-4","article-title":"Effects of intracerebroventricular dizocilpine (MK801) on dehydration-induced dipsogenic responses, plasma vasopressin and c-fos expression in the rat forebrain","volume":"784","author":"Xu","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib41","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0006-8993(98)00761-6","article-title":"Non-NMDA receptor antagonist-induced drinking in rat","volume":"808","author":"Xu","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib42","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0306-4522(96)00564-7","article-title":"Dizocilpine maleate, an N-methyl-d-aspartate antagonist, inhibits dipsogenic responses and C-Fos expression induced by intracerebral infusion of angiotensin II","volume":"78","author":"Xu","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2009.08.094_bib43","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0006-8993(93)90518-R","article-title":"Electrophysiological characterization of excitatory amino acid responses in rat lateral parabrachial neurons in vitro","volume":"611","author":"Zidichouski","year":"1993","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2009.08.094_bib44","doi-asserted-by":"crossref","first-page":"H1557","DOI":"10.1152\/ajpheart.1996.270.5.H1557","article-title":"Glutamate receptor subtypes mediate excitatory synaptic responses of rat lateral parabrachial neurons","volume":"270","author":"Zidichouski","year":"1996","journal-title":"Am. J. Physiol. Heart Circ. Physiol."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000689930901871X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000689930901871X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T01:57:38Z","timestamp":1739325458000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000689930901871X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":44,"alternative-id":["S000689930901871X"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2009.08.094","relation":{},"ISSN":["0006-8993"],"issn-type":[{"type":"print","value":"0006-8993"}],"subject":[],"published":{"date-parts":[[2009,11]]}}}