{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T16:32:40Z","timestamp":1791131560402,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.brainres.2010.03.060","type":"journal-article","created":{"date-parts":[[2010,4,12]],"date-time":"2010-04-12T06:04:41Z","timestamp":1271052281000},"page":"11-17","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["A potential role for adiponectin receptor 2 (AdipoR2) in the regulation of alcohol intake"],"prefix":"10.1016","volume":"1339","author":[{"given":"Vez","family":"Repunte-Canonigo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulvia","family":"Berton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Cottone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Reifel-Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda J.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisela","family":"Morales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Francesconi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro Paolo","family":"Sanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2010.03.060_bib1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.drugalcdep.2008.08.019","article-title":"Differential activation of the anterior cingulate cortex and caudate nucleus during a gambling simulation in persons with a family history of alcoholism: studies from the Oklahoma Family Health Patterns Project","volume":"100","author":"Acheson","year":"2009","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.brainres.2010.03.060_bib2","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1465-3362.2008.00023.x","article-title":"Hormones and drinking behaviour: new findings on ghrelin, insulin, leptin and volume-regulating hormones. An ESBRA Symposium report","volume":"28","author":"Addolorato","year":"2009","journal-title":"Drug Alcohol Rev."},{"key":"10.1016\/j.brainres.2010.03.060_bib3","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1210\/me.2007-0529","article-title":"Adipokines and the peripheral and neural control of energy balance","volume":"22","author":"Ahima","year":"2008","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.brainres.2010.03.060_bib4","doi-asserted-by":"crossref","first-page":"11533","DOI":"10.1073\/pnas.0504438102","article-title":"Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction","volume":"102","author":"Ahmed","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainres.2010.03.060_bib5","doi-asserted-by":"crossref","first-page":"5208","DOI":"10.1523\/JNEUROSCI.20-14-05208.2000","article-title":"Long-term potentiation of intrinsic excitability at the mossy fiber-granule cell synapse of rat cerebellum","volume":"20","author":"Armano","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2010.03.060_bib6","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0014-2999(99)00515-4","article-title":"Gamma-hydroxybutyrate inhibits excitatory postsynaptic potentials in rat hippocampal slices","volume":"380","author":"Berton","year":"1999","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.brainres.2010.03.060_bib7","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1096\/fj.06-5896com","article-title":"Glutathione-S-transferase expression in the brain: possible role in ethanol preference and longevity","volume":"20","author":"Bjork","year":"2006","journal-title":"Faseb J."},{"key":"10.1016\/j.brainres.2010.03.060_bib8","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1476-5381.1982.tb08780.x","article-title":"Blood alcohol levels in rats: non-uniform yields from intraperitoneal doses based on body weight","volume":"75","author":"Bloom","year":"1982","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.brainres.2010.03.060_bib9","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1037\/0735-7044.117.3.566","article-title":"Role of the anterior cingulate cortex in the control over behavior by Pavlovian conditioned stimuli in rats","volume":"117","author":"Cardinal","year":"2003","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.brainres.2010.03.060_bib10","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1038\/nature711","article-title":"Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1","volume":"415","author":"Costa","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.brainres.2010.03.060_bib11","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1111\/j.1530-0277.2007.00379.x","article-title":"Increased drinking during withdrawal from intermittent ethanol exposure is blocked by the CRF receptor antagonist D-Phe-CRF(12-41)","volume":"31","author":"Finn","year":"2007","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.brainres.2010.03.060_bib12","doi-asserted-by":"crossref","first-page":"9695","DOI":"10.1523\/JNEUROSCI.2014-06.2006","article-title":"Area postrema neurons are modulated by the adipocyte hormone adiponectin","volume":"26","author":"Fry","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2010.03.060_bib13","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.neuron.2006.09.006","article-title":"Leptin regulation of the mesoaccumbens dopamine pathway","volume":"51","author":"Fulton","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2010.03.060_bib14","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.neuron.2007.03.024","article-title":"Interoceptive basis to craving","volume":"54","author":"Gray","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2010.03.060_bib15","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1038\/sj.npp.1301494","article-title":"Neurotoxic consequences of chronic alcohol withdrawal: expression profiling reveals importance of gender over withdrawal severity","volume":"33","author":"Hashimoto","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainres.2010.03.060_bib16","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0306-4522(01)00167-1","article-title":"Action potential threshold of hippocampal pyramidal cells in vivo is increased by recent spiking activity","volume":"105","author":"Henze","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2010.03.060_bib17","doi-asserted-by":"crossref","first-page":"11318","DOI":"10.1073\/pnas.0812809106","article-title":"Requirement of central ghrelin signaling for alcohol reward","volume":"106","author":"Jerlhag","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainres.2010.03.060_bib18","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/nn1207","article-title":"Glutamatergic activation of anterior cingulate cortex produces an aversive teaching signal","volume":"7","author":"Johansen","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainres.2010.03.060_bib19","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1176\/appi.ajp.162.8.1403","article-title":"The neural basis of addiction: a pathology of motivation and choice","volume":"162","author":"Kalivas","year":"2005","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainres.2010.03.060_bib20","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1523\/JNEUROSCI.4372-04.2005","article-title":"Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA\/2J versus C57BL\/6J mice","volume":"25","author":"Kerns","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2010.03.060_bib21","article-title":"Neurocircuitry of Addiction","author":"Koob","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainres.2010.03.060_bib22","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1369-1600.2006.00001.x","article-title":"Imaging alcohol cue exposure in alcohol dependence using a PET 15O-H2O paradigm: results from a pilot study","volume":"11","author":"Lingford-Hughes","year":"2006","journal-title":"Addict. Biol."},{"key":"10.1016\/j.brainres.2010.03.060_bib23","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1210\/en.2006-0708","article-title":"Deficiency of adiponectin receptor 2 reduces diet-induced insulin resistance but promotes type 2 diabetes","volume":"148","author":"Liu","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.brainres.2010.03.060_bib24","unstructured":"Livak, K., 1997. ABI Prism 7700 Sequence Detection System, User Bulletin 2, PE Vol., eds. Applied Biosystems."},{"key":"10.1016\/j.brainres.2010.03.060_bib25","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1007\/s00213-005-0026-3","article-title":"Effect of pattern and number of chronic ethanol exposures on subsequent voluntary ethanol intake in C57BL\/6J mice","volume":"181","author":"Lopez","year":"2005","journal-title":"Psychopharmacology (Berl)."},{"key":"10.1016\/j.brainres.2010.03.060_bib26","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1210\/jc.2004-1979","article-title":"Effect of leptin replacement on brain structure in genetically leptin-deficient adults","volume":"90","author":"Matochik","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.brainres.2010.03.060_bib27","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0006-8993(98)00457-0","article-title":"Acute ethanol induces c-fos immunoreactivity in GABAergic neurons of the central nucleus of the amygdala","volume":"798","author":"Morales","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2010.03.060_bib28","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/sj.npp.1300295","article-title":"Differential brain activity in alcoholics and social drinkers to alcohol cues: relationship to craving","volume":"29","author":"Myrick","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainres.2010.03.060_bib29","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.peptides.2005.12.014","article-title":"Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin","volume":"27","author":"Pan","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.brainres.2010.03.060_bib30","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1126\/science.1089459","article-title":"Rapid rewiring of arcuate nucleus feeding circuits by leptin","volume":"304","author":"Pinto","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.brainres.2010.03.060_bib31","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/nm1029","article-title":"Adiponectin acts in the brain to decrease body weight","volume":"10","author":"Qi","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.brainres.2010.03.060_bib32","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.brainres.2006.09.115","article-title":"Increased expression of protein kinase A inhibitor alpha (PKI-alpha) and decreased PKA-regulated genes in chronic intermittent alcohol exposure","volume":"1138","author":"Repunte-Canonigo","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2010.03.060_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2010.03.063","article-title":"Genome-wide gene expression analysis identifies K-ras as a regulator of alcohol intake","volume":"1339","author":"Repunte-Canonigo","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2010.03.060_bib34","doi-asserted-by":"crossref","first-page":"3359","DOI":"10.1523\/JNEUROSCI.22-09-03359.2002","article-title":"Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region","volume":"22","author":"Sanna","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2010.03.060_bib35","doi-asserted-by":"crossref","first-page":"141","DOI":"10.2337\/diabetes.55.01.06.db05-1077","article-title":"Adiponectin does not cross the blood\u2013brain barrier but modifies cytokine expression of brain endothelial cells","volume":"55","author":"Spranger","year":"2006","journal-title":"Diabetes"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899310006347?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899310006347?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T04:48:52Z","timestamp":1559018932000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899310006347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":35,"alternative-id":["S0006899310006347"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2010.03.060","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}