{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T07:20:16Z","timestamp":1772608816460,"version":"3.50.1"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Kory and Scott Tabor Ataxia Research Fund"},{"DOI":"10.13039\/100000065","name":"NINDS","doi-asserted-by":"crossref","award":["R21NS056172"],"award-info":[{"award-number":["R21NS056172"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Minnesota Medical Foundation","award":["3761-9236-07"],"award-info":[{"award-number":["3761-9236-07"]}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources (NCRR)","doi-asserted-by":"crossref","award":["P41RR008079"],"award-info":[{"award-number":["P41RR008079"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Neuroscience Center Core Blueprint Award","award":["P30NS057091"],"award-info":[{"award-number":["P30NS057091"]}]},{"DOI":"10.13039\/100000097","name":"NCRR","doi-asserted-by":"crossref","award":["M01RR00400"],"award-info":[{"award-number":["M01RR00400"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1016\/j.brainres.2010.08.030","type":"journal-article","created":{"date-parts":[[2010,8,15]],"date-time":"2010-08-15T04:35:02Z","timestamp":1281846902000},"page":"200-210","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["1H MR spectroscopy in Friedreich's ataxia and ataxia with oculomotor apraxia type 2"],"prefix":"10.1016","volume":"1358","author":[{"given":"Isabelle","family":"Iltis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane","family":"Hutter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalaf O.","family":"Bushara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. Brent","family":"Clark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myron","family":"Gross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynn E.","family":"Eberly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher M.","family":"Gomez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fclin","family":"\u00d6z","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2010.08.030_bb0005","first-page":"91","article-title":"Characterization of two novel SETX mutations in AOA2 patients reveals aspects of the pathophysiological role of senataxin","volume":"1","author":"Airoldi","year":"2009","journal-title":"Neurogenetics"},{"key":"10.1016\/j.brainres.2010.08.030_bb0010","first-page":"1","article-title":"Epidemiological, clinical, paraclinical and molecular study of a cohort of 102 patients affected with autosomal recessive progressive cerebellar ataxia from Alsace, Eastern France: implications for clinical management","volume":"1","author":"Anheim","year":"2009","journal-title":"Neurogenetics"},{"key":"10.1016\/j.brainres.2010.08.030_bb0015","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1093\/brain\/awp211","article-title":"Ataxia with oculomotor apraxia type 2: clinical, biological and genotype\/phenotype correlation study of a cohort of 90 patients","volume":"132","author":"Anheim","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.brainres.2010.08.030_bb0020","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1212\/01.wnl.0000216135.59699.9b","article-title":"Autosomal recessive ataxia with peripheral neuropathy and elevated AFP: novel mutations in SETX","volume":"66","author":"Asaka","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2010.08.030_bb0025","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1055\/s-0029-1214424","article-title":"Ataxia with oculomotor apraxia type 2: novel mutations in six patients with juvenile age of onset and elevated serum alpha-fetoprotein","volume":"39","author":"Bernard","year":"2008","journal-title":"Neuropediatrics"},{"key":"10.1016\/j.brainres.2010.08.030_bb0030","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1093\/hmg\/9.2.275","article-title":"Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia","volume":"9","author":"Bradley","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.brainres.2010.08.030_bb0035","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1159\/000111347","article-title":"Multinuclear NMR studies on the energy metabolism of glial and neuronal cells","volume":"15","author":"Brand","year":"1993","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.brainres.2010.08.030_bb0040","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jns.2005.03.012","article-title":"Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia","volume":"233","author":"Calabrese","year":"2005","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.brainres.2010.08.030_bb0045","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1126\/science.271.5254.1423","article-title":"Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion","volume":"271","author":"Campuzano","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.brainres.2010.08.030_bb0050","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1159\/000017321","article-title":"N-acetyl aspartate: a marker for neuronal loss or mitochondrial dysfunction","volume":"20","author":"Clark","year":"1998","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.brainres.2010.08.030_bb0055","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1212\/01.wnl.0000208402.10512.4a","article-title":"Ataxia with oculomotor apraxia type 2: a clinical, pathologic, and genetic study","volume":"66","author":"Criscuolo","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2010.08.030_bb0060","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.neuroimage.2004.01.035","article-title":"ADC mapping of neurodegeneration in the brainstem and cerebellum of patients with progressive ataxias","volume":"22","author":"Della Nave","year":"2004","journal-title":"Neuroimage"},{"key":"10.1016\/j.brainres.2010.08.030_bb0065","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1136\/jnnp.2007.124297","article-title":"Brain structural damage in Friedreich's ataxia","volume":"79","author":"Della Nave","year":"2008","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.brainres.2010.08.030_bb0070","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1046\/j.1471-4159.2001.00285.x","article-title":"N-acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury","volume":"77","author":"Demougeot","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainres.2010.08.030_bb0075","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1002\/ana.20408","article-title":"Mutations in senataxin responsible for Quebec cluster of ataxia with neuropathy","volume":"57","author":"Duquette","year":"2005","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2010.08.030_bb0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/jmrb.1993.1055","article-title":"Absolute quantitation of water and metabolites in the human brain. I. Compartments and water","volume":"102","author":"Ernst","year":"1993","journal-title":"J. Magn. Reson."},{"key":"10.1016\/j.brainres.2010.08.030_bb0085","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1136\/jnnp.2006.096008","article-title":"How is disease progress in Friedreich's ataxia best measured? A study of four rating scales","volume":"78","author":"Fahey","year":"2007","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.brainres.2010.08.030_bb0090","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1212\/01.wnl.0000247661.19601.28","article-title":"Novel mutations in the senataxin DNA\/RNA helicase domain in ataxia with oculomotor apraxia 2","volume":"67","author":"Fogel","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2010.08.030_bb0095","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1007\/s00415-009-5079-5","article-title":"A combined voxel-based morphometry and 1H-MRS study in patients with Friedreich's ataxia","volume":"256","author":"Franca","year":"2009","journal-title":"J. Neurol."},{"key":"10.1016\/j.brainres.2010.08.030_bb0100","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/mus.21328","article-title":"Sensorimotor neuronopathy in ataxia with oculomotor apraxia type 2","volume":"40","author":"Gazulla","year":"2009","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.brainres.2010.08.030_bb0105","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/1099-1492(200005)13:3<129::AID-NBM619>3.0.CO;2-V","article-title":"Proton NMR chemical shifts and coupling constants for brain metabolites","volume":"13","author":"Govindaraju","year":"2000","journal-title":"NMR Biomed."},{"key":"10.1016\/j.brainres.2010.08.030_bb0110","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1023\/A:1007608615682","article-title":"Isoprostanes, novel markers of oxidative injury, help understanding the pathogenesis of neurodegenerative diseases","volume":"25","author":"Greco","year":"2000","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainres.2010.08.030_bb0115","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1373\/clinchem.2004.037630","article-title":"Plasma F2-isoprostanes and coronary artery calcification: the CARDIA Study","volume":"51","author":"Gross","year":"2005","journal-title":"Clin. Chem."},{"key":"10.1016\/j.brainres.2010.08.030_bb0120","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/jmri.21804","article-title":"Impact of cerebrospinal fluid contamination on brain metabolites evaluation with 1H-MR spectroscopy: a single voxel study of the cerebellar vermis in patients with degenerative ataxias","volume":"30","author":"Guerrini","year":"2009","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.brainres.2010.08.030_bb0125","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.neuint.2003.08.016","article-title":"Intercellular metabolic compartmentation in the brain: past, present and future","volume":"45","author":"Hertz","year":"2004","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainres.2010.08.030_bb0130","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00401-007-0220-y","article-title":"The dentate nucleus in Friedreich's ataxia: the role of iron-responsive proteins","volume":"114","author":"Koeppen","year":"2007","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.brainres.2010.08.030_bb0135","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0022-510X(85)90082-6","article-title":"Amino acid transport across the human blood\u2013CSF barrier. An evaluation graph for amino acid concentrations in cerebrospinal fluid","volume":"70","author":"Kruse","year":"1985","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.brainres.2010.08.030_bb0140","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1093\/brain\/awh080","article-title":"Frequency and phenotypic spectrum of ataxia with oculomotor apraxia 2: a clinical and genetic study in 18 patients","volume":"127","author":"Le Ber","year":"2004","journal-title":"Brain"},{"key":"10.1016\/j.brainres.2010.08.030_bb0145","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s11910-005-0066-4","article-title":"New autosomal recessive cerebellar ataxias with oculomotor apraxia","volume":"5","author":"Le Ber","year":"2005","journal-title":"Curr. Neurol. Neurosci. Rep."},{"key":"10.1016\/j.brainres.2010.08.030_bb0150","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1089\/ars.2006.8.438","article-title":"Friedreich's ataxia: from disease mechanisms to therapeutic interventions","volume":"8","author":"Lodi","year":"2006","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.brainres.2010.08.030_bb0155","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1148\/radiol.2232010722","article-title":"Proton MR spectroscopy of the cerebellum and pons in patients with degenerative ataxia","volume":"223","author":"Mascalchi","year":"2002","journal-title":"Radiology"},{"key":"10.1016\/j.brainres.2010.08.030_bb0160","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/ng1303","article-title":"Senataxin, the ortholog of a yeast RNA helicase, is mutant in ataxia-ocular apraxia 2","volume":"36","author":"Moreira","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2010.08.030_bb0165","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0076-6879(99)00106-8","article-title":"Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress","volume":"300","author":"Morrow","year":"1999","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.brainres.2010.08.030_bb0170","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1002\/mds.22038","article-title":"Urinary isoprostanes in Friedreich ataxia: lack of correlation with disease features","volume":"23","author":"Myers","year":"2008","journal-title":"Mov. Disord."},{"key":"10.1016\/j.brainres.2010.08.030_bb0175","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1471-2350-9-28","article-title":"A novel c.5308_5311delGAGA mutation in Senataxin in a Cypriot family with an autosomal recessive cerebellar ataxia","volume":"9","author":"Nicolaou","year":"2008","journal-title":"BMC Med. Genet."},{"key":"10.1016\/j.brainres.2010.08.030_bb0180","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1017\/S0317167100119596","article-title":"Brain lesions in Friedreich's ataxia","volume":"6","author":"Oppenheimer","year":"1979","journal-title":"Can. J. Neurol. Sci."},{"key":"10.1016\/j.brainres.2010.08.030_bb0185","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1136\/jnnp.57.1.51","article-title":"Magnetic resonance imaging in degenerative ataxic disorders","volume":"57","author":"Ormerod","year":"1994","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.brainres.2010.08.030_bb0190","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1212\/01.WNL.0000150906.52208.E7","article-title":"Assessment of adrenoleukodystrophy lesions by high field MRS in non-sedated pediatric patients","volume":"64","author":"\u00d6z","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2010.08.030_bb0195","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1002\/mds.23067","article-title":"Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status","volume":"25","author":"\u00d6z","year":"2010","journal-title":"Mov. Disord."},{"key":"10.1016\/j.brainres.2010.08.030_bb0200","doi-asserted-by":"crossref","first-page":"3831","DOI":"10.1523\/JNEUROSCI.5612-09.2010","article-title":"Noninvasive detection of presymptomatic and progressive neurodegeneration in a mouse model of spinocerebellar ataxia type 1","volume":"30","author":"\u00d6z","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2010.08.030_bb0205","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1148\/radiol.10091742","article-title":"Assessment of brain white matter fiber bundle atrophy in patients with Friedreich ataxia","volume":"255","author":"Pagani","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.brainres.2010.08.030_bb0210","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1750-1172-1-47","article-title":"Autosomal recessive cerebellar ataxias","volume":"1","author":"Palau","year":"2006","journal-title":"Orphanet J. Rare Dis."},{"issue":"Suppl 1","key":"10.1016\/j.brainres.2010.08.030_bb0215","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s00415-009-1003-2","article-title":"The pathogenesis of Friedreich ataxia and the structure and function of frataxin","volume":"256","author":"Pandolfo","year":"2009","journal-title":"J. Neurol."},{"key":"10.1016\/j.brainres.2010.08.030_bb0220","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/mrm.1910390110","article-title":"Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS","volume":"39","author":"Pouwels","year":"1998","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.brainres.2010.08.030_bb0225","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1055\/s-2007-973571","article-title":"Quantitative proton magnetic resonance spectroscopy of childhood adrenoleukodystrophy","volume":"29","author":"Pouwels","year":"1998","journal-title":"Neuropediatrics"},{"key":"10.1016\/j.brainres.2010.08.030_bb0230","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1002\/mrm.1910300604","article-title":"Estimation of metabolite concentrations from localized in vivo proton NMR spectra","volume":"30","author":"Provencher","year":"1993","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.brainres.2010.08.030_bb0235","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s00415-008-0707-z","article-title":"\u201cPseudodominant inheritance\u201d of ataxia with ocular apraxia type 2 (AOA2)","volume":"255","author":"Schols","year":"2008","journal-title":"J. Neurol."},{"key":"10.1016\/j.brainres.2010.08.030_bb0300","series-title":"Basic Neurochemistry: Molecular, Cellular and Medical Aspects","author":"Siegel","year":"1999"},{"key":"10.1016\/j.brainres.2010.08.030_bb0240","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/0306-4522(86)90121-1","article-title":"Quantification of immunogold labelling reveals enrichment of glutamate in mossy and parallel fibre terminals in cat cerebellum","volume":"19","author":"Somogyi","year":"1986","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2010.08.030_bb0245","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1212\/01.WNL.0000156802.15466.79","article-title":"Measuring Friedreich ataxia: interrater reliability of a neurologic rating scale","volume":"64","author":"Subramony","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2010.08.030_bb0250","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1083\/jcb.200701042","article-title":"Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage","volume":"177","author":"Suraweera","year":"2007","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.brainres.2010.08.030_bb0255","doi-asserted-by":"crossref","first-page":"3384","DOI":"10.1093\/hmg\/ddp278","article-title":"Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation","volume":"18","author":"Suraweera","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.brainres.2010.08.030_bb0260","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jns.2008.12.004","article-title":"Ataxia with oculomotor apraxia type 2: a clinical and genetic study of 19 patients","volume":"278","author":"Tazir","year":"2009","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.brainres.2010.08.030_bb0265","series-title":"16th Scientific Meeting of the International Society for Magnetic Resonance in Medicine, Toronto, Canada, 1624","article-title":"Refinement of the simulated basis set for LCModel analysis","author":"Tk\u00e1\u010d","year":"2008"},{"key":"10.1016\/j.brainres.2010.08.030_bb0270","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1002\/mrm.22086","article-title":"In vivo 1H NMR spectroscopy of the human brain at high magnetic fields: metabolite quantification at 4T vs. 7T","volume":"62","author":"Tk\u00e1\u010d","year":"2009","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.brainres.2010.08.030_bb0275","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/mrm.1910320209","article-title":"High frequency volume coils for clinical NMR imaging and spectroscopy","volume":"32","author":"Vaughan","year":"1994","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.brainres.2010.08.030_bb0280","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.brainres.2005.05.015","article-title":"1H magnetic resonance spectroscopy of autosomal ataxias","volume":"1049","author":"Viau","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2010.08.030_bb0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10048-003-0170-z","article-title":"Friedreich ataxia-update on pathogenesis and possible therapies","volume":"5","author":"Voncken","year":"2004","journal-title":"Neurogenetics"},{"key":"10.1016\/j.brainres.2010.08.030_bb0290","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1002\/mrm.20366","article-title":"MR spectroscopic evidence for glial increase but not for neuro-axonal damage in MS normal-appearing white matter","volume":"53","author":"Vrenken","year":"2005","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.brainres.2010.08.030_bb0295","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1093\/geronj\/37.3.313","article-title":"Elevation of cerebrospinal fluid lactate with aging in subjects with normal blood oxygen saturations","volume":"37","author":"Yesavage","year":"1982","journal-title":"J. Gerontol."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899310017774?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899310017774?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,8]],"date-time":"2018-12-08T16:20:30Z","timestamp":1544286030000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899310017774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":60,"alternative-id":["S0006899310017774"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2010.08.030","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2010,10]]}}}