{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T08:18:44Z","timestamp":1790151524197,"version":"4.0.1"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Grant-in-Aid for Young Scientists","award":["23790730"],"award-info":[{"award-number":["23790730"]}]},{"name":"Grant-in-Aid for Challenging Exploratory Research","award":["21659177"],"award-info":[{"award-number":["21659177"]}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.brainres.2012.05.001","type":"journal-article","created":{"date-parts":[[2012,5,16]],"date-time":"2012-05-16T00:23:24Z","timestamp":1337127804000},"page":"128-136","source":"Crossref","is-referenced-by-count":38,"special_numbering":"C","title":["Mild hypothermia facilitates the expression of cold-inducible RNA-binding protein and heat shock protein 70.1 in mouse brain"],"prefix":"10.1016","volume":"1466","author":[{"given":"Tomomi","family":"Kaneko","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiko","family":"Kibayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2012.05.001_bb0005","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1261\/rna.1179109","article-title":"Cold-inducible RNA binding protein (CIRP) expression is modulated by alternative mRNAs","volume":"15","author":"Al-Fageeh","year":"2009","journal-title":"RNA"},{"key":"10.1016\/j.brainres.2012.05.001_bb0010","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1210\/en.2003-0946","article-title":"Generation of a phenotypic array of hypothalamic neuronal cell models to study complex neuroendocrine disorders","volume":"145","author":"Belsham","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.brainres.2012.05.001_bb0015","first-page":"370","article-title":"Conditions required to produce a prolonged hypothermia in the mouse","volume":"2","author":"Bischoff","year":"1942","journal-title":"Cancer Res."},{"key":"10.1016\/j.brainres.2012.05.001_bb0020","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1038\/nm911","article-title":"A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia","volume":"9","author":"Borsello","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.brainres.2012.05.001_bb0025","doi-asserted-by":"crossref","first-page":"3963","DOI":"10.4049\/jimmunol.163.7.3963","article-title":"Inflammatory cytokines IL-1 alpha, IL-1 beta, IL-6, and TNF-\u03b1 impart neuroprotection to an excitotoxin through distinct pathways","volume":"163","author":"Carlson","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.brainres.2012.05.001_bb0030","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1152\/physrev.00008.2003","article-title":"Mammalian hibernation: cellular and molecular responses to depressed metabolism and low temperature","volume":"83","author":"Carey","year":"2003","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.brainres.2012.05.001_bb0035","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/BF01369918","article-title":"Terminal burrowing behaviour \u2014 a phenomenon of lethal hypothermia","volume":"108","author":"Carter","year":"1995","journal-title":"Int. J. Legal Med."},{"key":"10.1016\/j.brainres.2012.05.001_bb0040","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1179\/174313206X152537","article-title":"Rapid induction of brain hypothermia by endovascular intra-arterial perfusion","volume":"29","author":"Furuse","year":"2007","journal-title":"Neurol. Res."},{"key":"10.1016\/j.brainres.2012.05.001_bb0045","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1006\/bbrc.2001.5427","article-title":"Heat shock proteins: endogenous modulators of apoptotic cell death","volume":"286","author":"Garrido","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.brainres.2012.05.001_bb0050","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1097\/01.CCM.0000084845.76762.F4","article-title":"Nasopharyngeal cooling selectively and rapidly decreases brain temperature and attenuates neuronal damage, even if initiated at the onset of cardiopulmonary resuscitation in rats","volume":"31","author":"Hagioka","year":"2003","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.brainres.2012.05.001_bb0055","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0010-4825(02)00030-6","article-title":"Numerical studies on the effect of lowering temperature on the oxygen transport during brain hypothermia resuscitation","volume":"32","author":"Ji","year":"2002","journal-title":"Comput. Biol. Med."},{"key":"10.1016\/j.brainres.2012.05.001_bb0060","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.1271\/bbb.70498","article-title":"Impaired thermoregulatory ability of oxytocin-deficient mice during cold-exposure","volume":"71","author":"Kasahara","year":"2007","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.brainres.2012.05.001_bb0065","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s00414-008-0278-7","article-title":"Hyperthermia combined with ethanol administration induces c-fos expression in the central amygdaloid nucleus of the mouse brain. A possible mechanism of heatstroke under the influence of ethanol intake","volume":"123","author":"Kibayashi","year":"2009","journal-title":"Int. J. Legal Med."},{"key":"10.1016\/j.brainres.2012.05.001_bb0070","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s00213-008-1224-6","article-title":"Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats","volume":"202","author":"Lapiz-Bluhm","year":"2009","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.brainres.2012.05.001_bb0075","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0031-9384(02)01004-1","article-title":"Effect of cold acclimation and repeated swimming on opioid and nonopioid swim stress-induced analgesia in selectively bred mice","volume":"78","author":"Lapo","year":"2003","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.brainres.2012.05.001_bb0080","doi-asserted-by":"crossref","first-page":"2905","DOI":"10.1161\/hs1201.099604","article-title":"Targeted hsp70.1 disruption increases infarction volume after focal cerebral ischemia in mice","volume":"32","author":"Lee","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2012.05.001_bb0085","doi-asserted-by":"crossref","first-page":"14768","DOI":"10.1016\/S0021-9258(17)36691-7","article-title":"Transient cold shock induces the heat shock response upon recovery at 37degrees C in human cells","volume":"269","author":"Liu","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainres.2012.05.001_bb0090","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/01.ana.0000188639.39844.f6","article-title":"Mild hypothermia promotes pro-inflammatory cytokine production in monocytes","volume":"18","author":"Matsui","year":"2006","journal-title":"J. Neurosurg. Anesthesiol."},{"key":"10.1016\/j.brainres.2012.05.001_bb0095","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1097\/01.CCM.0000147441.39670.37","article-title":"Clinical trial of a novel surface cooling system for fever control in neurocritical care patients","volume":"32","author":"Mayer","year":"2004","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.brainres.2012.05.001_bb0100","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.bbi.2010.09.003","article-title":"Interleukin (IL)-1 and IL-6 regulation of neural progenitor cell proliferation with hippocampal injury: differential regulatory pathways in the subgranular zone (SGZ) of the adolescent and mature mouse brain","volume":"25","author":"McPherson","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.brainres.2012.05.001_bb0105","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/00024382-200205000-00001","article-title":"The interaction between Hsp70 and TNF-alpha expression: a novel mechanism for protection of the myocardium against post-injury depression","volume":"17","author":"Meng","year":"2002","journal-title":"Shock"},{"key":"10.1016\/j.brainres.2012.05.001_bb0110","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1387\/ijdb.082643pm","article-title":"Mammalian hibernation: differential gene expression and novel application of epigenetic controls","volume":"53","author":"Morin","year":"2009","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.brainres.2012.05.001_bb0115","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1159\/000028315","article-title":"Is the growth of brown adipocytes necessary for cold acclimation in mice?","volume":"59","author":"Nishimura","year":"1999","journal-title":"Pharmacology"},{"key":"10.1016\/j.brainres.2012.05.001_bb0120","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1083\/jcb.137.4.899","article-title":"A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth","volume":"137","author":"Nishiyama","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.brainres.2012.05.001_bb0125","first-page":"289","article-title":"Decreased expression of cold-inducible RNA-binding protein (CIRP) in male germ cells at elevated temperature","volume":"152","author":"Nishiyama","year":"1998","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.brainres.2012.05.001_bb0130","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1006\/bbrc.1998.8482","article-title":"Diurnal change of the cold-inducible RNA-binding protein (Cirp) expression in mouse brain","volume":"245","author":"Nishiyama","year":"1998","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.brainres.2012.05.001_bb0135","doi-asserted-by":"crossref","first-page":"e73","DOI":"10.1093\/nar\/gng073","article-title":"Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis","volume":"31","author":"Peirson","year":"2003","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.brainres.2012.05.001_bb0140","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1038\/ncb0901-839","article-title":"Heat-shock protein 70 antagonizes apoptosis-inducing factor","volume":"3","author":"Ravagnan","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.brainres.2012.05.001_bb0145","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.bbamcr.2006.02.007","article-title":"Cirp protects against tumor necrosis factor-alpha-induced apoptosis via activation of extracellular signal-regulated kinase","volume":"1763","author":"Sakurai","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.brainres.2012.05.001_bb0150","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1042\/cs0860133","article-title":"Secretion of ions and pharmacological responsiveness in the mouse paw sweat gland","volume":"86","author":"Sato","year":"1994","journal-title":"Clin. Sci."},{"key":"10.1016\/j.brainres.2012.05.001_bb0155","first-page":"809874","article-title":"Molecular mechanisms underlying hypothermia-induced neuroprotection","volume":"2011","author":"Shintani","year":"2011","journal-title":"Stroke Res. Treat."},{"key":"10.1016\/j.brainres.2012.05.001_bb0160","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0304-3940(97)00296-6","article-title":"Effects of hypothermia on the neuronal activity, [Ca2+]i accumulation and ATP levels during oxygen and\/or glucose deprivation in hippocampal slices of guinea pigs","volume":"227","author":"Takata","year":"1997","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2012.05.001_bb0165","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1042\/AN20100016","article-title":"Increased Plp1 gene expression leads to massive microglial cell activation and inflammation throughout the brain","volume":"2","author":"Tatar","year":"2010","journal-title":"ASN Neuro."},{"key":"10.1016\/j.brainres.2012.05.001_bb0170","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1097\/WNR.0b013e32832a2f32","article-title":"Hypothermia enhances heat-shock protein 70 production in ischemic brains","volume":"20","author":"Terao","year":"2009","journal-title":"Neuroreport"},{"key":"10.1016\/j.brainres.2012.05.001_bb0175","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1379\/1466-1268(2002)007<0387:DHSGHR>2.0.CO;2","article-title":"Differential heat shock gene hsp70-1 response to toxicants revealed by in vivo study of lungs in transgenic mice","volume":"7","author":"Wirth","year":"2002","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.brainres.2012.05.001_bb0180","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s12028-008-9064-0","article-title":"Intranasal perfluorochemical spray for preferential brain cooling in sheep","volume":"8","author":"Wolfson","year":"2008","journal-title":"Neurocrit. Care"},{"key":"10.1016\/j.brainres.2012.05.001_bb0185","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1161\/01.STR.31.1.86","article-title":"Mild resuscitative hypothermia to improve neurological outcome after cardiac arrest. A clinical feasibility trial. Hypothermia After Cardiac Arrest (HACA) Study Group","volume":"31","author":"Zeiner","year":"2000","journal-title":"Stroke"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899312008165?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899312008165?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,22]],"date-time":"2023-06-22T15:38:19Z","timestamp":1687448299000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899312008165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":37,"alternative-id":["S0006899312008165"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2012.05.001","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}