{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:46:39Z","timestamp":1791265599519,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003627","name":"Rural Development Administration","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003627","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.brainres.2012.05.032","type":"journal-article","created":{"date-parts":[[2012,5,24]],"date-time":"2012-05-24T13:24:14Z","timestamp":1337865854000},"page":"158-166","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Dopaminergic differentiation of neural progenitors derived from placental mesenchymal stem cells in the brains of Parkinson's disease model rats and alleviation of asymmetric rotational behavior"],"prefix":"10.1016","volume":"1466","author":[{"given":"Saeyoung","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eungpil","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Eun","family":"Koh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sungho","family":"Maeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won-don","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinho","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Insop","family":"Shim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Jay","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2012.05.032_bb0005","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1016\/0140-6736(91)92989-F","article-title":"Parkinson's disease: pathophysiology","volume":"337","author":"Agid","year":"1991","journal-title":"Lancet"},{"key":"10.1016\/j.brainres.2012.05.032_bb0010","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1002\/jnr.20151","article-title":"Human skin-derived stem cells migrate throughout forebrain and differentiate into astrocytes after injection into adult mouse brain","volume":"77","author":"Belicchi","year":"2004","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.brainres.2012.05.032_bb0015","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.stem.2011.06.013","article-title":"Large-scale analysis reveals acquisition of lineage-specific chromosomal aberrations in human adult stem cells","volume":"9","author":"Ben-David","year":"2011","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.brainres.2012.05.032_bb0020","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/cne.22038","article-title":"Stem cells for ischemic brain injury: a critical review","volume":"515","author":"Burns","year":"2009","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2012.05.032_bb0025","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.bbrc.2007.03.157","article-title":"Placenta derived multipotent stem cells induced to differentiate into insulin-positive cells","volume":"357","author":"Chang","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.brainres.2012.05.032_bb0030","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1111\/j.1582-4934.2010.01034.x","article-title":"MafA promotes the reprogramming of placenta-derived multipotent stem cells into pancreatic islets-like and insulin-positive cells","volume":"15","author":"Chiou","year":"2010","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.brainres.2012.05.032_bb0035","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.brainres.2009.11.041","article-title":"Multiple neurogenic and neurorescue effects of human mesenchymal stem cell after transplantation in an experimental model of Parkinson's disease","volume":"1311","author":"Cova","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2012.05.032_bb0040","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","article-title":"Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement","volume":"8","author":"Dominici","year":"2006","journal-title":"Cytotherapy"},{"key":"10.1016\/j.brainres.2012.05.032_bb0045","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1056\/NEJM200103083441002","article-title":"Transplantation of embryonic dopamine neurons for severe Parkinson's disease","volume":"344","author":"Freed","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.brainres.2012.05.032_bb0050","doi-asserted-by":"crossref","first-page":"267","DOI":"10.2217\/rme.10.3","article-title":"Stem cell-derived dopamine neurons for brain repair in Parkinson's disease","volume":"5","author":"Fricker-Gates","year":"2010","journal-title":"Regen. Med."},{"key":"10.1016\/j.brainres.2012.05.032_bb0055","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1634\/stemcells.22-5-649","article-title":"Human placenta-derived cells have mesenchymal stem\/progenitor cell potential","volume":"22","author":"Fukuchi","year":"2004","journal-title":"Stem Cells"},{"key":"10.1016\/j.brainres.2012.05.032_bb0065","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/(SICI)1096-9861(19971117)388:2<211::AID-CNE3>3.0.CO;2-4","article-title":"Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra","volume":"388","author":"Hersch","year":"1997","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2012.05.032_bb0075","series-title":"Parkinson's Disease","first-page":"59","author":"Higgins","year":"2006"},{"key":"10.1016\/j.brainres.2012.05.032_bb0070","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1111\/j.1469-7580.2006.00654.x","article-title":"Mesencephalic human neural progenitor cells transplanted into the neonatal hemiparkinsonian rat striatum differentiate into neurons and improve motor behaviour","volume":"209","author":"Hovakimyan","year":"2006","journal-title":"J. Anat."},{"key":"10.1016\/j.brainres.2012.05.032_bb0080","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1136\/jnnp.2007.131045","article-title":"Parkinson's disease: clinical features and diagnosis","volume":"79","author":"Jankovic","year":"2008","journal-title":"J. Neurol. Neurosurg."},{"key":"10.1016\/j.brainres.2012.05.032_bb0090","first-page":"103","article-title":"Tyrosine hydroxylase","volume":"70","author":"Kaufman","year":"1995","journal-title":"Adv. Enzymol. Relat. Areas Mol. Biol."},{"key":"10.1016\/j.brainres.2012.05.032_bb0100","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1002\/jnr.22054","article-title":"Stem cell-based cell therapy in neurological diseases: a review","volume":"87","author":"Kim","year":"2009","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.brainres.2012.05.032_bb0095","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/nature00900","article-title":"Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease","volume":"418","author":"Kim","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.brainres.2012.05.032_bb0105","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1056\/NEJM198804073181402","article-title":"Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications","volume":"318","author":"Kish","year":"1988","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.brainres.2012.05.032_bb0110","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.brainres.2009.12.001","article-title":"Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats","volume":"1315","author":"Kranz","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2012.05.032_bb0120","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1172\/JCI40543","article-title":"Stem cells in human neurodegenerative disorders\u2014time for clinical translation","volume":"120","author":"Lindvall","year":"2010","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainres.2012.05.032_bb0125","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/ana.10720","article-title":"A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease","volume":"54","author":"Olanow","year":"2003","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2012.05.032_bb0130","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.placenta.2010.12.027","article-title":"Neural progenitors generated from the mesenchymal stem cells of first-trimester human placenta matured in the hypoxic\u2013ischemic rat brain and mediated restoration of locomotor activity","volume":"32","author":"Park","year":"2011","journal-title":"Placenta"},{"key":"10.1016\/j.brainres.2012.05.032_bb0135","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.2967\/jnumed.106.037796","article-title":"Modulation of dopaminergic and glutamatergic brain function: PET studies on Parkinsonian rats","volume":"48","author":"Pellegrino","year":"2007","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.brainres.2012.05.032_bb0140","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1126\/science.284.5411.143","article-title":"Multilineage potential of adult human mesenchymal stem cells","volume":"284","author":"Pittenger","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.brainres.2012.05.032_bb0145","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1634\/stemcells.2006-0386","article-title":"Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease","volume":"25","author":"Rodr\u00edguez-G\u00f3mez","year":"2007","journal-title":"Stem Cells"},{"key":"10.1016\/j.brainres.2012.05.032_bb0150","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.stem.2011.12.005","article-title":"Limited acquisition of chromosomal aberrations in human adult mesenchymal stromal cells","volume":"10","author":"Senseb\u00e9","year":"2012","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.brainres.2012.05.032_bb0155","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/ana.21204","article-title":"Dopamine transporter relation to dopamine turnover in Parkinson's disease: a positron emission tomography study","volume":"62","author":"Sossi","year":"2007","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2012.05.032_bb0160","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1182\/blood-2009-05-219907","article-title":"Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation","volume":"115","author":"Tarte","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.brainres.2012.05.032_bb0165","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1089\/ten.2004.10.1136","article-title":"Mesengenic progenitor cells derived from human placenta. Mesengenic progenitor cells derived from human placenta","volume":"10","author":"Wulf","year":"2004","journal-title":"Tissue Eng."},{"key":"10.1016\/j.brainres.2012.05.032_bb0170","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1038\/sj.jcbfm.9600439","article-title":"Quantification of dopamine transporter binding using [18F]FP-\u00df-CIT and positron emission tomography","volume":"27","author":"Yaqub","year":"2007","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainres.2012.05.032_bb0175","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1038\/374640a0","article-title":"Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development","volume":"374","author":"Zhou","year":"1995","journal-title":"Nature"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899312009304?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899312009304?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T17:49:27Z","timestamp":1757785767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899312009304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":32,"alternative-id":["S0006899312009304"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2012.05.032","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dopaminergic differentiation of neural progenitors derived from placental mesenchymal stem cells in the brains of Parkinson's disease model rats and alleviation of asymmetric rotational behavior","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2012.05.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}