{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T20:42:50Z","timestamp":1743626570132},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Northwest Rett Syndrome Foundation; International Rett Syndrome Association"},{"name":"IRSA20808 (S.R.O); International Rett Syndrome Foundation, IRSF (V.M.)"},{"name":"NIH","award":["8P51-OD-011092-53"],"award-info":[{"award-number":["8P51-OD-011092-53"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.brainres.2012.12.009","type":"journal-article","created":{"date-parts":[[2012,12,14]],"date-time":"2012-12-14T15:01:53Z","timestamp":1355497313000},"page":"104-114","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Correcting deregulated Fxyd1 expression ameliorates a behavioral impairment in a mouse model of Rett syndrome"],"prefix":"10.1016","volume":"1496","author":[{"given":"Valerie","family":"Matagne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarojini","family":"Budden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio R.","family":"Ojeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Raber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2012.12.009_bib1","doi-asserted-by":"crossref","first-page":"18208","DOI":"10.1073\/pnas.1012104107","article-title":"Correction of respiratory disorders in a mouse model of Rett syndrome","volume":"107","author":"Abdala","year":"2010","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"key":"10.1016\/j.brainres.2012.12.009_bib2","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1093\/cercor\/bhj114","article-title":"Ventromedial prefrontal cortex is obligatory for consolidation and reconsolidation of object recognition memory","volume":"16","author":"Akirav","year":"2006","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.brainres.2012.12.009_bib3","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/13810","article-title":"Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG binding protein 2","volume":"23","author":"Amir","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2012.12.009_bib4","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/jnr.22608","article-title":"Brain region-specific expression of Fxyd1, an MeCP2 target gene, is regulated by epigenetic mechanisms","volume":"89","author":"Banine","year":"2011","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.brainres.2012.12.009_bib5","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/nrg1878","article-title":"Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized","volume":"7","author":"Bienvenu","year":"2006","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.brainres.2012.12.009_bib6","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1093\/hmg\/9.9.1377","article-title":"MECP2 mutations account for most cases of typical forms of Rett syndrome","volume":"9","author":"Bienvenu","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.brainres.2012.12.009_bib7","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1093\/hmg\/ddr602","article-title":"Pharmacological interference with the glucocorticoid system influences symptoms and lifespan in a mouse model of Rett syndrome","volume":"21","author":"Braun","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.brainres.2012.12.009_bib8","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.neuron.2007.10.001","article-title":"The story of Rett syndrome: from clinic to neurobiology","volume":"56","author":"Chahrour","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2012.12.009_bib9","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.neuron.2005.12.027","article-title":"The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression","volume":"49","author":"Chang","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2012.12.009_bib10","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/nn.3027","article-title":"MeCP2: only 100% will do","volume":"15","author":"Chao","year":"2012","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainres.2012.12.009_bib11","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1126\/science.1086446","article-title":"Depression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2","volume":"302","author":"Chen","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.brainres.2012.12.009_bib12","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1042\/BST0380498","article-title":"Reversibility of functional deficits in experimental models of Rett syndrome","volume":"38","author":"Cobb","year":"2010","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.brainres.2012.12.009_bib13","doi-asserted-by":"crossref","first-page":"RE1","DOI":"10.1126\/stke.2003.166.re1","article-title":"FXYD proteins: new tissue-specific regulators of the ubiquitous Na,K-ATPase","volume":"2003","author":"Crambert","year":"2003","journal-title":"Sci. STKE"},{"key":"10.1016\/j.brainres.2012.12.009_bib14","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/j.1601-183X.2009.00551.x","article-title":"Early postnatal behavioral changes in the Mecp2-308 truncation mouse model of Rett syndrome","volume":"9","author":"De Filippis","year":"2010","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.brainres.2012.12.009_bib15","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1038\/npp.2011.301","article-title":"Modulation of RhoGTPases improves the behavioral phenotype and reverses astrocytic deficits in a mouse model of Rett syndrome","volume":"37","author":"De Filippis","year":"2012","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainres.2012.12.009_bib16","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1093\/hmg\/ddm007","article-title":"FXYD1 is an MeCP2 target gene overexpressed in the brains of Rett syndrome patients and Mecp2-null mice","volume":"16","author":"Deng","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.brainres.2012.12.009_bib17","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0166-4328(88)90157-X","article-title":"A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data","volume":"31","author":"Ennaceur","year":"1988","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2012.12.009_bib18","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/PL00005603","article-title":"Spontaneous object recognition and object location memory in rats: The effects of lesions in the cingulate cortices, the medial prefrontal cortex, the cingulum bundle and the fornix","volume":"113","author":"Ennaceur","year":"1997","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.brainres.2012.12.009_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/BJ20110648","article-title":"MeCP2 and Rett syndrome: reversibility and potential avenues for therapy","volume":"439","author":"Gadalla","year":"2011","journal-title":"Biochem. J."},{"key":"10.1016\/j.brainres.2012.12.009_bib20","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.1365-2826.2008.01812.x","article-title":"FXYD1, a modulator of Na(+),K(+)-ATPase activity, facilitates female sexual development by maintaining GnRH neuronal excitability","volume":"21","author":"Garcia-Rudaz","year":"2008","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.brainres.2012.12.009_bib21","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1073\/pnas.0610593104","article-title":"Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2","volume":"104","author":"Giacometti","year":"2007","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"key":"10.1016\/j.brainres.2012.12.009_bib22","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/1471-2202-11-53","article-title":"Downstream targets of methyl CpG binding protein 2 and their abnormal expression in the frontal cortex of the human Rett syndrome brain","volume":"11","author":"Gibson","year":"2010","journal-title":"BMC. Neurosci."},{"key":"10.1016\/j.brainres.2012.12.009_bib23","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1126\/science.1138389","article-title":"Reversal of neurological defects in a mouse model of Rett syndrome","volume":"315","author":"Guy","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.brainres.2012.12.009_bib24","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1111\/j.1651-2227.1995.tb13809.x","article-title":"Rett syndrome: Cinical peculiarities and biological mysteries","volume":"84","author":"Hagberg","year":"1995","journal-title":"Acta Paediatr."},{"key":"10.1016\/j.brainres.2012.12.009_bib25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/ng1491","article-title":"Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome","volume":"37","author":"Horike","year":"2005","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2012.12.009_bib26","doi-asserted-by":"crossref","first-page":"H1982","DOI":"10.1152\/ajpheart.00142.2004","article-title":"Hypertrophy, increased ejection fraction, and reduced Na,K-ATPase activity in phospholemman-deficient mice","volume":"288","author":"Jia","year":"2005","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.brainres.2012.12.009_bib27","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1471-2350-8-36","article-title":"Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets","volume":"8","author":"Jordan","year":"2007","journal-title":"BMC Med. Genet."},{"key":"10.1016\/j.brainres.2012.12.009_bib28","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1523\/JNEUROSCI.4599-08.2009","article-title":"Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment","volume":"29","author":"Kadish","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2012.12.009_bib29","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.biopsych.2005.06.006","article-title":"Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1\/2 activation in the prefrontal cortex of mice","volume":"59","author":"Kamei","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainres.2012.12.009_bib30","doi-asserted-by":"crossref","first-page":"5033","DOI":"10.1128\/MCB.01665-05","article-title":"Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome","volume":"26","author":"Kriaucionis","year":"2006","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.brainres.2012.12.009_bib31","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/hipo.20060","article-title":"Study of CA1 place cell activity and exploratory behavior following spatial and nonspatial changes in the environment","volume":"15","author":"Lenck-Santini","year":"2005","journal-title":"Hippocampus"},{"key":"10.1016\/j.brainres.2012.12.009_bib32","doi-asserted-by":"crossref","first-page":"6033","DOI":"10.1073\/pnas.0401626101","article-title":"Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice","volume":"101","author":"Luikenhuis","year":"2004","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"key":"10.1016\/j.brainres.2012.12.009_bib33","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1126\/science.1090842","article-title":"DNA methylation-related chromatin remodeling in activity-dependent Bdnf gene regulation","volume":"302","author":"Martinowich","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.brainres.2012.12.009_bib34","doi-asserted-by":"crossref","first-page":"18267","DOI":"10.1073\/pnas.0608702103","article-title":"Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome","volume":"103","author":"McGill","year":"2006","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"key":"10.1016\/j.brainres.2012.12.009_bib35","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0166-4328(98)00032-1","article-title":"The medial frontal cortex and temporal memory: tests using spontaneous exploratory behaviour in the rat","volume":"97","author":"Mitchell","year":"1998","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2012.12.009_bib36","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/hmg\/ddi016","article-title":"Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome","volume":"14","author":"Moretti","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.brainres.2012.12.009_bib37","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1523\/JNEUROSCI.2623-05.2006","article-title":"Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome","volume":"26","author":"Moretti","year":"2006","journal-title":"J. Neurosci."},{"issue":"54","key":"10.1016\/j.brainres.2012.12.009_bib38","first-page":"58","article-title":"Concurrent mRNA and protein extraction from the same experimental sample using a commercially available column-based RNA preparation kit","volume":"40","author":"Morse","year":"2006","journal-title":"BioTechniques"},{"key":"10.1016\/j.brainres.2012.12.009_bib39","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1534\/genetics.106.061481","article-title":"Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype","volume":"174","author":"Nadler","year":"2006","journal-title":"Genetics"},{"key":"10.1016\/j.brainres.2012.12.009_bib40","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/ana.410420104","article-title":"Rett syndrome: A disorder affecting early brain growth","volume":"42","author":"Naidu","year":"1997","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2012.12.009_bib41","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1093\/hmg\/ddi229","article-title":"Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome","volume":"14","author":"Nuber","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.brainres.2012.12.009_bib42","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1093\/hmg\/ddl124","article-title":"Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome","volume":"15","author":"Peddada","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.brainres.2012.12.009_bib43","doi-asserted-by":"crossref","DOI":"10.1093\/brain\/aws096","article-title":"Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome","author":"Robinson","year":"2012","journal-title":"Brain"},{"key":"10.1016\/j.brainres.2012.12.009_bib44","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1111\/j.1460-9568.2007.05466.x","article-title":"Treatment with desipramine improves breathing and survival in a mouse model for Rett syndrome","volume":"25","author":"Roux","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.brainres.2012.12.009_bib45","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.physbeh.2009.12.025","article-title":"Cognitive and social functions and growth factors in a mouse model of Rett syndrome","volume":"100","author":"Schaevitz","year":"2010","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.brainres.2012.12.009_bib46","first-page":"173","article-title":"Rett syndrome: Clinical features, genetic considerations, and the search for a biological marker","volume":"12","author":"Sekul","year":"1992","journal-title":"Curr. Neurol."},{"key":"10.1016\/j.brainres.2012.12.009_bib47","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0896-6273(02)00768-7","article-title":"Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3","volume":"35","author":"Shahbazian","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2012.12.009_bib48","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.neuroscience.2007.02.009","article-title":"Behavioral and anatomical abnormalities in Mecp2 mutant mice: a model for Rett syndrome","volume":"146","author":"Stearns","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2012.12.009_bib49","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1073\/pnas.0812394106","article-title":"Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice","volume":"106","author":"Tropea","year":"2009","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"key":"10.1016\/j.brainres.2012.12.009_bib50","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/nn1648","article-title":"Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia","volume":"9","author":"Walter","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainres.2012.12.009_bib51","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1086\/302690","article-title":"Rett syndrome and beyond: recurrent spontaneous and familial MECP2 mutations at CpG hotspots","volume":"65","author":"Wan","year":"1999","journal-title":"Am. J. Hum. Genet."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899312018768?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899312018768?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T11:55:13Z","timestamp":1643889313000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899312018768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":51,"alternative-id":["S0006899312018768"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2012.12.009","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]}}}