{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T20:10:31Z","timestamp":1769976631429,"version":"3.49.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"the Institut Clinique de la Souris (ICS)"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.brainres.2013.10.003","type":"journal-article","created":{"date-parts":[[2013,10,15]],"date-time":"2013-10-15T22:32:40Z","timestamp":1381876360000},"page":"32-40","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: Pathophysiological relevance for Alzheimer's disease?"],"prefix":"10.1016","volume":"1542","author":[{"given":"Alexis","family":"Koutseff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Mittelhaeuser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim","family":"Essabri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan","family":"Auwerx","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Meziane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2013.10.003_bib1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1385\/JMN:23:3:157","article-title":"APOE genotype effects on Alzheimer's disease onset and epidemiology","volume":"23","author":"Ashford","year":"2004","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.brainres.2013.10.003_bib2","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.vascn.2008.12.002","article-title":"Flow cytometric analysis of BrdU incorporation as a high-throughput method for measuring adult neurogenesis in the mouse","volume":"59","author":"Balu","year":"2009","journal-title":"J. Pharmacol. Toxicol. Methods"},{"key":"10.1016\/j.brainres.2013.10.003_bib3","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jneumeth.2006.03.026","article-title":"A rapid method for the quantification of mouse hippocampal neurogenesis in vivo by flow cytometry. Validation with conventional and enhanced immunohistochemical methods","volume":"157","author":"Bilsland","year":"2006","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.brainres.2013.10.003_bib4","doi-asserted-by":"crossref","first-page":"4867","DOI":"10.1523\/JNEUROSCI.19-12-04867.1999","article-title":"Expression of human apolipoprotein E3 or E4 in the brains of Apoe-\/- mice: isoform-specific effects on neurodegeneration","volume":"19","author":"Buttini","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2013.10.003_bib5","doi-asserted-by":"crossref","first-page":"10539","DOI":"10.1523\/JNEUROSCI.22-24-10539.2002","article-title":"Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation","volume":"22","author":"Buttini","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2013.10.003_bib6","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1038\/13197","article-title":"Restoring production of hippocampal neurons in old age","volume":"2","author":"Cameron","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainres.2013.10.003_bib7","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1007\/s00335-004-2393-1","article-title":"Mouse functional genomics requires standardization of mouse handling and housing conditions","volume":"15","author":"Champy","year":"2004","journal-title":"Mamm. Genome"},{"key":"10.1016\/j.brainres.2013.10.003_bib8","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1126\/science.8346443","article-title":"Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families","volume":"261","author":"Corder","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.brainres.2013.10.003_bib9","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0304-3940(93)90748-A","article-title":"Neurogenesis persists in the subependymal layer of the adult mouse brain","volume":"149","author":"Corotto","year":"1993","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2013.10.003_bib10","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1016\/j.neuroscience.2009.01.033","article-title":"Apolipoprotein E-genotype dependent hippocampal and cortical responses to traumatic brain injury","volume":"159","author":"Crawford","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2013.10.003_bib11","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00429-009-0232-6","article-title":"APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis","volume":"214","author":"Crews","year":"2010","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.brainres.2013.10.003_bib12","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/0006-8993(70)90026-0","article-title":"Postnatal neurogenesis in the caudate nucleus and nucleus accumbens septi in the rat","volume":"21","author":"Das","year":"1970","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2013.10.003_bib13","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1093\/cercor\/13.8.845","article-title":"Regional effects of wheel running and environmental enrichment on cell genesis and microglia proliferation in the adult murine neocortex","volume":"13","author":"Ehninger","year":"2003","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.brainres.2013.10.003_bib14","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1523\/JNEUROSCI.17-07-02492.1997","article-title":"Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation","volume":"17","author":"Gould","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2013.10.003_bib15","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1016\/S0022-2275(20)41390-2","article-title":"Effects of apolipoprotein E, beta-very low density lipoproteins, and cholesterol on the extension of neurites by rabbit dorsal root ganglion neurons in vitro","volume":"33","author":"Handelmann","year":"1992","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.brainres.2013.10.003_bib16","article-title":"Apolipoprotein E: from lipid transport to neurobiology","author":"Hauser","year":"2010","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.brainres.2013.10.003_bib17","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0197-4580(03)00090-3","article-title":"Prominent decline of newborn cell proliferation, differentiation, and apoptosis in the aging dentate gyrus, in absence of an age-related hypothalamus-pituitary-adrenal axis activation","volume":"25","author":"Heine","year":"2004","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.brainres.2013.10.003_bib18","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1101\/gad.187336.112","article-title":"Orchestrating transcriptional control of adult neurogenesis","volume":"26","author":"Hsieh","year":"2012","journal-title":"Genes Dev."},{"key":"10.1016\/j.brainres.2013.10.003_bib19","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1385\/JMN:23:3:189","article-title":"Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease","volume":"23","author":"Huang","year":"2004","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.brainres.2013.10.003_bib20","first-page":"627","article-title":"Molecular and cellular mechanisms of apolipoprotein E4 neurotoxicity and potential therapeutic strategies","volume":"9","author":"Huang","year":"2006","journal-title":"Curr. Opin. Drug Discov. Dev."},{"key":"10.1016\/j.brainres.2013.10.003_bib21","doi-asserted-by":"crossref","first-page":"S79","DOI":"10.1212\/01.wnl.0000192102.41141.9e","article-title":"Apolipoprotein E and Alzheimer disease","volume":"66","author":"Huang","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2013.10.003_bib22","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s11064-006-9251-3","article-title":"Genetic influences on outcome following traumatic brain injury","volume":"32","author":"Jordan","year":"2007","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainres.2013.10.003_bib23","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1523\/JNEUROSCI.22-03-00635.2002","article-title":"Why new neurons? Possible functions for adult hippocampal neurogenesis","volume":"22","author":"Kempermann","year":"2002","journal-title":"J. Neurosci. Official J. Soc. Neurosci."},{"key":"10.1016\/j.brainres.2013.10.003_bib24","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1242\/dev.00203","article-title":"Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice","volume":"130","author":"Kempermann","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.brainres.2013.10.003_bib25","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/nrn3319","article-title":"New neurons for \u2018survival of the fittest","volume":"13","author":"Kempermann","year":"2012","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.brainres.2013.10.003_bib26","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1172\/JCI6172","article-title":"Apo E structure determines VLDL clearance and atherosclerosis risk in mice","volume":"103","author":"Knouff","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainres.2013.10.003_bib27","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1523\/JNEUROSCI.16-06-02027.1996","article-title":"Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation","volume":"16","author":"Kuhn","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2013.10.003_bib28","doi-asserted-by":"crossref","first-page":"17169","DOI":"10.1073\/pnas.0708228104","article-title":"Diminished adult neurogenesis in the marmoset brain precedes old age","volume":"104","author":"Leuner","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainres.2013.10.003_bib29","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.1471-4159.2006.04189.x","article-title":"Environmental enrichment stimulates neurogenesis in apolipoprotein E3 and neuronal apoptosis in apolipoprotein E4 transgenic mice","volume":"100","author":"Levi","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainres.2013.10.003_bib30","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.stem.2009.10.015","article-title":"GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice","volume":"5","author":"Li","year":"2009","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.brainres.2013.10.003_bib31","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0896-6273(93)90281-U","article-title":"Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone","volume":"11","author":"Luskin","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2013.10.003_bib32","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1126\/science.3283935","article-title":"Apolipoprotein E: cholesterol transport protein with expanding role in cell biology","volume":"240","author":"Mahley","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.brainres.2013.10.003_bib33","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1749-6632.1996.tb34412.x","article-title":"Apolipoprotein E. Structure, function, and possible roles in Alzheimer's disease","volume":"777","author":"Mahley","year":"1996","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.brainres.2013.10.003_bib34","doi-asserted-by":"crossref","first-page":"5644","DOI":"10.1073\/pnas.0600549103","article-title":"Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease","volume":"103","author":"Mahley","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainres.2013.10.003_bib35","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/nrn1886","article-title":"Ageing and neuronal vulnerability","volume":"7","author":"Mattson","year":"2006","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.brainres.2013.10.003_bib36","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1126\/science.8171342","article-title":"Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro","volume":"264","author":"Nathan","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.brainres.2013.10.003_bib37","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1089\/scd.2006.15.359","article-title":"Neurogenesis in diseases of the central nervous system","volume":"15","author":"Phillips","year":"2006","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.brainres.2013.10.003_bib38","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.neuint.2004.03.022","article-title":"Phosphodiesterase type 5 inhibition improves early memory consolidation of object information","volume":"45","author":"Prickaerts","year":"2004","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainres.2013.10.003_bib39","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1001\/archneur.1994.00540240033012","article-title":"Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E epsilon 4 allele","volume":"51","author":"Reed","year":"1994","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.brainres.2013.10.003_bib40","doi-asserted-by":"crossref","unstructured":"Riddle, D.R., Lichtenwalner, R.J., 2007. Neurogenesis in the adult and aging brain. In: Riddle, D.R. (Eds), Brain Aging: Models, Methods, and Mechanisms. Frontiers in Neuroscience, Vol., Boca Raton, FL.","DOI":"10.1201\/9781420005523"},{"key":"10.1016\/j.brainres.2013.10.003_bib41","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1146\/annurev.med.47.1.387","article-title":"Apolipoprotein E alleles as risk factors in Alzheimer's disease","volume":"47","author":"Roses","year":"1996","journal-title":"Annu. Rev. Med."},{"key":"10.1016\/j.brainres.2013.10.003_bib42","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1111\/j.1749-6632.1998.tb10653.x","article-title":"Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg","volume":"855","author":"Roses","year":"1998","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.brainres.2013.10.003_bib43","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1126\/science.1083328","article-title":"Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants","volume":"301","author":"Santarelli","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.brainres.2013.10.003_bib44","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1212\/WNL.43.8.1467","article-title":"Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease","volume":"43","author":"Saunders","year":"1993","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2013.10.003_bib45","article-title":"Apolipoprotein E: Implications for AD neurobiology, epidemiology and risk assessment","author":"Schipper","year":"2009","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.brainres.2013.10.003_bib46","article-title":"Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease","author":"Simpson","year":"2010","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.brainres.2013.10.003_bib47","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.nlm.2007.05.001","article-title":"Neurogenesis decreases with age in the canine hippocampus and correlates with cognitive function","volume":"88","author":"Siwak-Tapp","year":"2007","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.brainres.2013.10.003_bib48","doi-asserted-by":"crossref","first-page":"4725","DOI":"10.1073\/pnas.92.11.4725","article-title":"Apolipoprotein E and Alzheimer disease","volume":"92","author":"Strittmatter","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainres.2013.10.003_bib49","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.exger.2006.05.013","article-title":"Estradiol regulation of astroglia and apolipoprotein E: an important role in neuronal regeneration","volume":"42","author":"Struble","year":"2007","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.brainres.2013.10.003_bib50","doi-asserted-by":"crossref","first-page":"17972","DOI":"10.1074\/jbc.272.29.17972","article-title":"Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis","volume":"272","author":"Sullivan","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainres.2013.10.003_bib51","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1172\/JCI2673","article-title":"Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe\u204e2","volume":"102","author":"Sullivan","year":"1998","journal-title":"J. Clin. Invest."},{"issue":"10","key":"10.1016\/j.brainres.2013.10.003_bib52","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a006296","article-title":"The genetics of Alzheimer disease","volume":"2","author":"Tanzi","year":"2012","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.brainres.2013.10.003_bib53","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1002\/jnr.10378","article-title":"Adult neurogenesis and neural stem cells of the central nervous system in mammals","volume":"69","author":"Taupin","year":"2002","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.brainres.2013.10.003_bib54","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/S0140-6736(97)04318-3","article-title":"Association of apolipoprotein E polymorphism with outcome after head injury","volume":"350","author":"Teasdale","year":"1997","journal-title":"Lancet"},{"issue":"Suppl 1","key":"10.1016\/j.brainres.2013.10.003_bib55","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1601-183X.2007.00379.x","article-title":"Changes in adult neurogenesis in neurodegenerative diseases: cause or consequence?","volume":"7","author":"Thompson","year":"2008","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.brainres.2013.10.003_bib56","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0959-440X(94)90212-7","article-title":"Lipoproteins, neurobiology, and Alzheimer's disease: structure and function of apolipoprotein E","volume":"4","author":"Weisgraber","year":"1994","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.brainres.2013.10.003_bib57","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1097\/00041433-199404000-00007","article-title":"The role of apolipoprotein E in the nervous system","volume":"5","author":"Weisgraber","year":"1994","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.brainres.2013.10.003_bib58","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3109\/00207450903464579","article-title":"Proliferation, migration, and neuronal differentiation of the endogenous neural progenitors in hippocampus after fimbria fornix transection","volume":"120","author":"Zou","year":"2010","journal-title":"Int. J. Neurosci."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899313013395?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899313013395?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T17:00:12Z","timestamp":1762102812000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899313013395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":58,"alternative-id":["S0006899313013395"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2013.10.003","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: Pathophysiological relevance for Alzheimer's disease?","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2013.10.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}