{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T02:02:12Z","timestamp":1792202532368,"version":"4.4.0"},"reference-count":28,"publisher":"Elsevier BV","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.brainres.2014.01.011","type":"journal-article","created":{"date-parts":[[2014,1,17]],"date-time":"2014-01-17T09:32:33Z","timestamp":1389951153000},"page":"64-71","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":113,"special_numbering":"C","title":["Temporal profile of the vascular anatomy evaluated by 9.4-T magnetic resonance angiography and histopathological analysis in mice lacking RNF213: A susceptibility gene for moyamoya disease"],"prefix":"10.1016","volume":"1552","author":[{"given":"Shinya","family":"Sonobe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miki","family":"Fujimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuniyasu","family":"Niizuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Nishijima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsuo","family":"Kikuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natsuko","family":"Arai-Ichinoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeo","family":"Kure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teiji","family":"Tominaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2014.01.011_bib1","doi-asserted-by":"crossref","first-page":"8218","DOI":"10.1158\/0008-5472.CAN-04-4355","article-title":"Magnetic resonance angiography visualization of abnormal tumor vasculature in genetically engineered mice","volume":"65","author":"Brubaker","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.brainres.2014.01.011_bib2","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00062-011-0113-2","article-title":"Comparison of digital subtraction angiography, micro-computed tomography angiography and magnetic resonance angiography in the assessment of the cerebrovascular system in live mice","volume":"22","author":"Figueiredo","year":"2012","journal-title":"Clin. Neuroradiol."},{"key":"10.1016\/j.brainres.2014.01.011_bib3","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.surneu.2008.10.009","article-title":"Increased expression of serum Matrix Metalloproteinase-9 in patients with moyamoya disease","volume":"72","author":"Fujimura","year":"2009","journal-title":"Surg. Neurol."},{"key":"10.1016\/j.brainres.2014.01.011_bib4","doi-asserted-by":"crossref","first-page":"2861","DOI":"10.1161\/01.CIR.102.23.2861","article-title":"Remodeling of carotid artery is associated with increased expression of matrix metalloproteinases in mouse blood flow cessation model","volume":"102","author":"Godin","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.brainres.2014.01.011_bib5","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jneumeth.2011.11.024","article-title":"Visualization of macroscopic cerebral vessel anatomy \u2013 a new and reliable technique in mice","volume":"204","author":"Hasan","year":"2012","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.brainres.2014.01.011_bib6","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.bbrc.2013.07.004","article-title":"Downregulation of Securin by the variant RNF213 R4810K (rs112735431, G>A) reduces angiogenic activity of induced pluripotent stem cell-derived vascular endothelial cells from moyamoya patients","volume":"438","author":"Hitomi","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.brainres.2014.01.011_bib7","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.bbrc.2013.08.067","article-title":"The moyamoya disease susceptibility variant RNF213 R4810K (rs112735431) induces genomic instability by mitotic abnormality","volume":"439","author":"Hitomi","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.brainres.2014.01.011_bib8","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1086\/302243","article-title":"Mapping of a familial moyamoya disease gene to chromosome 3p24.2\u2013p26","volume":"64","author":"Ikeda","year":"1999","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.brainres.2014.01.011_bib9","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1177\/088307380001500307","article-title":"Linkage analysis of moyamoya disease on chromosome 6","volume":"15","author":"Inoue","year":"2000","journal-title":"J. Child Neurol."},{"key":"10.1016\/j.brainres.2014.01.011_bib10","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1007\/s00701-012-1472-4","article-title":"Outer-diameter narrowing of the internal carotid and middle cerebral arteries in moyamoya disease detected on 3D constructive interference in steady-state MR image: is arterial constrictive remodeling a major pathogenesis?","volume":"154","author":"Kaku","year":"2012","journal-title":"Acta Neurochir. (Wien)"},{"key":"10.1016\/j.brainres.2014.01.011_bib11","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/jhg.2010.132","article-title":"A genome-wide association study identifies RNF213 as the first Moyamoya disease gene","volume":"56","author":"Kamada","year":"2011","journal-title":"J. Hum. Genet."},{"key":"10.1016\/j.brainres.2014.01.011_bib12","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1136\/jnnp.2009.191817","article-title":"Plasma matrix metalloproteinases, cytokines and angiogenic factors in moyamoya disease","volume":"81","author":"Kang","year":"2010","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.brainres.2014.01.011_bib13","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1161\/STROKEAHA.109.562264","article-title":"Association of thyroid autoantibodies with moyamoya-type cerebrovascular disease: a prospective study","volume":"41","author":"Kim","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2014.01.011_bib14","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.bbrc.2013.02.015","article-title":"Ablation of Rnf213 retards progression of diabetes in the Akita mouse","volume":"432","author":"Kobayashi","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.brainres.2014.01.011_bib15","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1161\/01.ATV.17.10.2238","article-title":"Remodeling with neointima formation in the mouse carotid artery after cessation of blood flow","volume":"17","author":"Kumar","year":"1997","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.brainres.2014.01.011_bib16","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1161\/STROKEAHA.107.490714","article-title":"Prevalence and clinicoepidemiological features of moyamoya disease in Japan: findings from a nationwide epidemiological survey","volume":"39","author":"Kuriyama","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2014.01.011_bib17","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1161\/STROKEAHA.110.608471","article-title":"Increased thyroid function and elevated thyroid autoantibodies in pediatric patients with moyamoya disease: a case-control study","volume":"42","author":"Li","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2014.01.011_bib18","doi-asserted-by":"crossref","first-page":"e22542","DOI":"10.1371\/journal.pone.0022542","article-title":"Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development","volume":"6","author":"Liu","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.brainres.2014.01.011_bib19","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1097\/00001756-199805110-00012","article-title":"Differences in the cerebrovascular anatomy of C57black\/6 and SV129 mice","volume":"9","author":"Maeda","year":"1998","journal-title":"Neuroreport"},{"key":"10.1016\/j.brainres.2014.01.011_bib20","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1212\/WNL.0b013e318249f71f","article-title":"Homozygous c.14576G>A variant of RNF213 predicts early-onset and severe form of moyamoya disease","volume":"78","author":"Miyatake","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2014.01.011_bib21","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/BF02155663","article-title":"Cerebral haemorrhage in Moyamoya disease at autopsy","volume":"392","author":"Oka","year":"1981","journal-title":"Virchows Arch. A Pathol. Anat. Histol"},{"key":"10.1016\/j.brainres.2014.01.011_bib22","doi-asserted-by":"crossref","first-page":"245","DOI":"10.2176\/nmc.52.245","article-title":"Health labour sciences research grant for research on measures for infractable diseases. Guidelines for diagnosis and treatment of moyamoya disease (Spontaneous Occlusion of the Circle of Willis)","volume":"52","author":"Research Committee on the Pathology and Treatment of Spontaneous Occlusion of the Circle of Willis","year":"2012","journal-title":"Neurol. Med. Chir. (Tokyo)"},{"key":"10.1016\/j.brainres.2014.01.011_bib23","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/s10038-004-0143-6","article-title":"A novel susceptibility locus for moyamoya disease on chromosome 8q23","volume":"49","author":"Sakurai","year":"2004","journal-title":"J. Hum. Genet."},{"key":"10.1016\/j.brainres.2014.01.011_bib24","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1001\/archneur.1969.00480090076012","article-title":"Cerebrovascular \u201cmoyamoya\u201c disease. Disease showing abnormal net-like vessels in base of brain","volume":"20","author":"Suzuki","year":"1969","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.brainres.2014.01.011_bib25","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1227\/01.NEU.0000249275.87310.FF","article-title":"Expression of hypoxia-inducing factor-1 alpha and endoglin in intimal hyperplasia of the middle cerebral artery of patients with Moyamoya disease","volume":"60","author":"Takagi","year":"2007","journal-title":"Neurosurgery"},{"key":"10.1016\/j.brainres.2014.01.011_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2176\/nmc.47.1","article-title":"Histological features of middle cerebral arteries from patients treated for Moyamoya disease","volume":"47","author":"Takagi","year":"2007","journal-title":"Neurol. Med. Chir. (Tokyo)"},{"key":"10.1016\/j.brainres.2014.01.011_bib27","doi-asserted-by":"crossref","first-page":"e48179","DOI":"10.1371\/journal.pone.0048179","article-title":"Molecular analysis of RNF213 gene for moyamoya disease in the Chinese Han population","volume":"7","author":"Wu","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.brainres.2014.01.011_bib28","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1161\/01.STR.31.4.930","article-title":"Linkage of familial moyamoya disease (spontaneous occlusion of the circle of Willis) to chromosome 17q25","volume":"31","author":"Yamauchi","year":"2000","journal-title":"Stroke"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000689931400064X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000689931400064X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,7]],"date-time":"2018-10-07T04:50:22Z","timestamp":1538887822000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000689931400064X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":28,"alternative-id":["S000689931400064X"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2014.01.011","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Temporal profile of the vascular anatomy evaluated by 9.4-T magnetic resonance angiography and histopathological analysis in mice lacking RNF213: A susceptibility gene for moyamoya disease","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2014.01.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}