{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:51:13Z","timestamp":1792785073233,"version":"4.5.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1003462"],"award-info":[{"award-number":["1003462"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1057751"],"award-info":[{"award-number":["1057751"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1022308"],"award-info":[{"award-number":["1022308"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institute of Health","award":["HL080624"],"award-info":[{"award-number":["HL080624"]}]},{"name":"National Institute of Health","award":["C026714"],"award-info":[{"award-number":["C026714"]}]},{"name":"National Institute of Health","award":["C026429"],"award-info":[{"award-number":["C026429"]}]},{"name":"Australian Research Council Future Fellowship","award":["FT120100170"],"award-info":[{"award-number":["FT120100170"]}],"id":[{"id":"https:\/\/ror.org\/05mmh0f86","id-type":"ROR","asserted-by":"crossref"}]},{"name":"University of Queensland International Scholarship","id":[{"id":"https:\/\/ror.org\/00rqy9422","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Australian Postgraduate Awards"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.brainres.2015.04.057","type":"journal-article","created":{"date-parts":[[2015,5,7]],"date-time":"2015-05-07T13:03:32Z","timestamp":1431003812000},"page":"71-87","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX"],"prefix":"10.1016","volume":"1616","author":[{"given":"Diana","family":"Vidovic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lachlan","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracey J.","family":"Harvey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yee Hsieh","family":"Evelyn Heng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron G.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Osinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Hughes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard M.","family":"Gronostajski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy L.","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Piper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2015.04.057_bib1","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1111\/j.1460-9568.2006.05002.x","article-title":"A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells","volume":"24","author":"Baas","year":"2006","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.brainres.2015.04.057_bib2","doi-asserted-by":"crossref","first-page":"12328","DOI":"10.1523\/JNEUROSCI.4000-08.2008","article-title":"Specific glial populations regulate hippocampal morphogenesis","volume":"28","author":"Barry","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2015.04.057_bib3","doi-asserted-by":"crossref","first-page":"4539","DOI":"10.1242\/dev.00661","article-title":"Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4","volume":"130","author":"Blackshear","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.brainres.2015.04.057_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-0173(85)90016-5","article-title":"Ependyma: normal and pathological. A review of the literature","volume":"356","author":"Bruni","year":"1985","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2015.04.057_bib5","first-page":"8","article-title":"The transcription factor Nfix is essential for normal brain development","author":"Campbell","year":"2008","journal-title":"BMC Dev. Biol."},{"key":"10.1016\/j.brainres.2015.04.057_bib6","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1111\/j.1471-4159.2006.03804.x","article-title":"Nuclear factor-I regulates glial fibrillary acidic protein gene expression in astrocytes differentiated from cortical precursor cells","volume":"97","author":"Cebolla","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainres.2015.04.057_bib7","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/ng1302","article-title":"The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate","volume":"36","author":"Chae","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2015.04.057_bib8","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/(SICI)1097-0177(199703)208:3<313::AID-AJA3>3.0.CO;2-L","article-title":"Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development","volume":"208","author":"Chaudhry","year":"1997","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.brainres.2015.04.057_bib9","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1007\/s00381-011-1546-2","article-title":"Hydrocephalus in aqueductal stenosis","volume":"27","author":"Cinalli","year":"2011","journal-title":"Childs Nerv. Syst."},{"key":"10.1016\/j.brainres.2015.04.057_bib10","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0169-328X(97)00357-4","article-title":"Complex expression pattern of the SCO-spondin gene in the bovine subcommissural organ: toward an explanation for Reissner\u05f3s fiber complexity","volume":"55","author":"Creveaux","year":"1998","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.brainres.2015.04.057_bib11","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00401-009-0624-y","article-title":"Ependymal cells: biology and pathology","volume":"119","author":"Del Bigio","year":"2010","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.brainres.2015.04.057_bib12","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1093\/hmg\/ddn324","article-title":"Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages","volume":"18","author":"Dietrich","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.brainres.2015.04.057_bib13","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1007\/s10571-013-9961-4","article-title":"Nuclear factor one X regulates bobby sox during development of the mouse forebrain","volume":"33","author":"Dixon","year":"2013","journal-title":"Cell Mol. Neurobiol."},{"key":"10.1016\/j.brainres.2015.04.057_bib14","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1097\/01.jnen.0000171648.86718.bb","article-title":"Ependymal denudation and alterations of the subventricular zone occur in human fetuses with a moderate communicating hydrocephalus","volume":"64","author":"Dominguez-Pinos","year":"2005","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.brainres.2015.04.057_bib15","doi-asserted-by":"crossref","first-page":"3855","DOI":"10.1128\/MCB.02293-06","article-title":"Nuclear factor I X deficiency causes brain malformation and severe skeletal defects","volume":"27","author":"Driller","year":"2007","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.brainres.2015.04.057_bib16","doi-asserted-by":"crossref","first-page":"e65478","DOI":"10.1371\/journal.pone.0065478","article-title":"Heterozygosity for nuclear factor one X affects hippocampal-dependent behaviour in mice","volume":"8","author":"Harris","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.brainres.2015.04.057_bib17","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/dvdy.24182","article-title":"Nuclear factor one transcription factors: divergent functions in developmental versus adult stem cell populations","volume":"3","author":"Harris","year":"2015","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.brainres.2015.04.057_bib18","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1159\/000330651","article-title":"Nuclear factor I genes regulate neuronal migration","volume":"20","author":"Heng","year":"2012","journal-title":"Neurosignals"},{"key":"10.1016\/j.brainres.2015.04.057_bib19","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/cercor\/bhs307","article-title":"NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis","volume":"24","author":"Heng","year":"2014","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.brainres.2015.04.057_bib20","doi-asserted-by":"crossref","DOI":"10.1093\/cercor\/bhu253","article-title":"NFIX regulates proliferation and migration within the murine SVZ neurogenic niche","author":"Heng","year":"2015","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.brainres.2015.04.057_bib21","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.ydbio.2011.04.002","article-title":"Mesenchymal nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation","volume":"354","author":"Hsu","year":"2011","journal-title":"Dev. Biol."},{"key":"10.1016\/j.brainres.2015.04.057_bib22","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1152\/physiol.00039.2008","article-title":"SCO-ping out the mechanisms underlying the etiology of hydrocephalus","volume":"24","author":"Huh","year":"2009","journal-title":"Physiology"},{"key":"10.1016\/j.brainres.2015.04.057_bib23","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1093\/jnen\/60.11.1105","article-title":"A programmed ependymal denudation precedes congenital hydrocephalus in the hyh mutant mouse","volume":"60","author":"Jimenez","year":"2001","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.brainres.2015.04.057_bib24","doi-asserted-by":"crossref","first-page":"e28426","DOI":"10.4161\/tisb.28426","article-title":"Structure and function of the ependymal barrier and diseases associated with ependyma disruption","volume":"2","author":"Jimenez","year":"2014","journal-title":"Tissue Barriers"},{"key":"10.1016\/j.brainres.2015.04.057_bib25","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1365-2990.1988.tb00887.x","article-title":"Inherited prenatal hydrocephalus in the H-Tx rat: a morphological study","volume":"14","author":"Jones","year":"1988","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.brainres.2015.04.057_bib26","doi-asserted-by":"crossref","first-page":"11511","DOI":"10.1523\/JNEUROSCI.0182-12.2012","article-title":"Nuclear factor kappaB activation impairs ependymal ciliogenesis and links neuroinflammation to hydrocephalus formation","volume":"32","author":"Lattke","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2015.04.057_bib27","doi-asserted-by":"crossref","first-page":"e29041","DOI":"10.1371\/journal.pone.0029041","article-title":"Congenital hydrocephalus and abnormal subcommissural organ development in Sox3 transgenic mice","volume":"7","author":"Lee","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.brainres.2015.04.057_bib28","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1002\/jnr.23238","article-title":"Riding the wave of ependymal cilia: genetic susceptibility to hydrocephalus in primary ciliary dyskinesia","volume":"91","author":"Lee","year":"2013","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.brainres.2015.04.057_bib29","doi-asserted-by":"crossref","first-page":"4061","DOI":"10.1242\/dev.127.18.4061","article-title":"Ectopic engrailed 1 expression in the dorsal midline causes cell death, abnormal differentiation of circumventricular organs and errors in axonal pathfinding","volume":"127","author":"Louvi","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.brainres.2015.04.057_bib30","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s12035-008-8048-6","article-title":"Nuclear factor one transcription factors in CNS development","volume":"39","author":"Mason","year":"2009","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.brainres.2015.04.057_bib31","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.siny.2012.06.004","article-title":"Pathophysiology of congenital and neonatal hydrocephalus","volume":"17","author":"McAllister","year":"2012","journal-title":"Semin. Fetal Neonatal Med."},{"key":"10.1016\/j.brainres.2015.04.057_bib32","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.cell.2010.01.027","article-title":"Nfix regulates fetal-specific transcription in developing skeletal muscle","volume":"140","author":"Messina","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.brainres.2015.04.057_bib33","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.brainres.2011.01.048","article-title":"Hydrocephalus and abnormal subcommissural organ in mice lacking presenilin-1 in Wnt1 cell lineages","volume":"1382","author":"Nakajima","year":"2011","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2015.04.057_bib34","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.devcel.2008.12.014","article-title":"Committed neuronal precursors confer astrocytic potential on residual neural precursor cells","volume":"16","author":"Namihira","year":"2009","journal-title":"Dev. Cell"},{"key":"10.1016\/j.brainres.2015.04.057_bib35","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1097\/NEN.0b013e3182a2d5fe","article-title":"Disruption of CDH2\/N-cadherin-based adherens junctions leads to apoptosis of ependymal cells and denudation of brain ventricular walls","volume":"72","author":"Oliver","year":"2013","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.brainres.2015.04.057_bib36","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1097\/nen.0b013e31815c1952","article-title":"Patterned neuropathologic events occurring in hyh congenital hydrocephalic mutant mice","volume":"66","author":"Paez","year":"2007","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.brainres.2015.04.057_bib37","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s13238-012-2098-2","article-title":"Inactivation of Cdc42 in embryonic brain results in hydrocephalus with ependymal cell defects in mice","volume":"4","author":"Peng","year":"2013","journal-title":"Protein Cell"},{"key":"10.1016\/j.brainres.2015.04.057_bib38","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1097\/00005072-199802000-00010","article-title":"Spontaneous congenital hydrocephalus in the mutant mouse hyh. Changes in the ventricular system and the subcommissural organ","volume":"57","author":"Perez-Figares","year":"1998","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.brainres.2015.04.057_bib39","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1002\/1097-0029(20010301)52:5<591::AID-JEMT1043>3.0.CO;2-7","article-title":"Subcommissural organ, cerebrospinal fluid circulation, and hydrocephalus","volume":"52","author":"Perez-Figares","year":"2001","journal-title":"Microsc. Res. Tech."},{"issue":"Suppl. 1","key":"10.1016\/j.brainres.2015.04.057_bib40","doi-asserted-by":"crossref","first-page":"i11","DOI":"10.1093\/cercor\/bhp027","article-title":"Neuropilin 1-Sema signalling regulates crossing of cingulate pioneering axons during development of the corpus callosum","volume":"19","author":"Piper","year":"2009","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.brainres.2015.04.057_bib41","doi-asserted-by":"crossref","first-page":"9127","DOI":"10.1523\/JNEUROSCI.6167-09.2010","article-title":"NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1","volume":"30","author":"Piper","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2015.04.057_bib42","doi-asserted-by":"crossref","first-page":"3532","DOI":"10.1002\/cne.22721","article-title":"Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum","volume":"519","author":"Piper","year":"2011","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2015.04.057_bib43","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1523\/JNEUROSCI.2319-13.2014","article-title":"NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development","volume":"34","author":"Piper","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2015.04.057_bib44","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1186\/1471-2164-12-181","article-title":"Nuclear factor I revealed as family of promoter binding transcription activators","volume":"12","author":"Pjanic","year":"2011","journal-title":"BMC Genomics"},{"key":"10.1016\/j.brainres.2015.04.057_bib45","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/cne.21645","article-title":"Nuclear factor I gene expression in the developing forebrain","volume":"508","author":"Plachez","year":"2008","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2015.04.057_bib46","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s00401-012-0992-6","article-title":"Astrocytes acquire morphological and functional characteristics of ependymal cells following disruption of ependyma in hydrocephalus","volume":"124","author":"Roales-Bujan","year":"2012","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.brainres.2015.04.057_bib47","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1002\/(SICI)1097-0029(19980415)41:2<98::AID-JEMT2>3.0.CO;2-M","article-title":"The subcommissural organ","volume":"41","author":"Rodriguez","year":"1998","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.brainres.2015.04.057_bib48","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.gep.2013.04.004","article-title":"Expression of the murine transcription factor SOX3 during embryonic and adult neurogenesis","volume":"13","author":"Rogers","year":"2013","journal-title":"Gene Expr. Patterns"},{"key":"10.1016\/j.brainres.2015.04.057_bib49","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1750-3639.2010.00432.x","article-title":"Neuroependymal denudation is in progress in full-term human foetal spina bifida aperta","volume":"21","author":"Sival","year":"2011","journal-title":"Brain Pathol."},{"key":"10.1016\/j.brainres.2015.04.057_bib50","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1523\/JNEUROSCI.1108-04.2005","article-title":"Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis","volume":"25","author":"Spassky","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2015.04.057_bib51","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1128\/MCB.25.2.685-698.2005","article-title":"The transcription factor gene Nfib is essential for both lung maturation and brain development","volume":"25","author":"Steele-Perkins","year":"2005","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.brainres.2015.04.057_bib52","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/nn.2555","article-title":"Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus","volume":"13","author":"Tissir","year":"2010","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainres.2015.04.057_bib53","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1743-8454-5-3","article-title":"The subcommissural organ of the rat secretes Reissner\u05f3s fiber glycoproteins and CSF-soluble proteins reaching the internal and external CSF compartments","volume":"5","author":"Vio","year":"2008","journal-title":"Cerebrospin. Fluid Res."},{"key":"10.1016\/j.brainres.2015.04.057_bib54","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1093\/jnen\/62.10.1019","article-title":"Cellular mechanisms involved in the stenosis and obliteration of the cerebral aqueduct of hyh mutant mice developing congenital hydrocephalus","volume":"62","author":"Wagner","year":"2003","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.brainres.2015.04.057_bib55","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1093\/hmg\/ddq031","article-title":"Deletion of the Parkin co-regulated gene causes defects in ependymal ciliary motility and hydrocephalus in the quakingviable mutant mouse","volume":"19","author":"Wilson","year":"2010","journal-title":"Hum. Mol. Genet."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899315003716?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899315003716?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,7]],"date-time":"2022-05-07T09:05:56Z","timestamp":1651914356000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899315003716"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":55,"alternative-id":["S0006899315003716"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2015.04.057","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2015.04.057","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}