{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T17:42:35Z","timestamp":1762623755402,"version":"3.44.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["5R00HD058044"],"award-info":[{"award-number":["5R00HD058044"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.brainres.2016.06.015","type":"journal-article","created":{"date-parts":[[2016,6,11]],"date-time":"2016-06-11T23:13:20Z","timestamp":1465686800000},"page":"287-296","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Perinatal midline astrocyte development is impaired in fibroblast growth factor 8 hypomorphic mice"],"prefix":"10.1016","volume":"1646","author":[{"given":"Courtney E.","family":"Stewart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina M.","family":"Corella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brittany D.","family":"Samberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula T.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan L.","family":"Linscott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilson C.J.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2016.06.015_bib1","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1002\/cne.23298","article-title":"Cell death atlas of the postnatal mouse ventral forebrain and hypothalamus: effects of age and sex","volume":"521","author":"Ahern","year":"2013","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2016.06.015_bib2","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ydbio.2013.02.001","article-title":"Gli3 is required in Emx1+ progenitors for the development of the corpus callosum","volume":"376","author":"Amaniti","year":"2013","journal-title":"Dev. Biol."},{"key":"10.1016\/j.brainres.2016.06.015_bib3","doi-asserted-by":"crossref","first-page":"5043","DOI":"10.1242\/dev.125.24.5043","article-title":"Semaphorins act as attractive and repulsive guidance signals during the development of cortical projections","volume":"125","author":"Bagnard","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.brainres.2016.06.015_bib4","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0896-6273(02)00561-5","article-title":"Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain","volume":"33","author":"Bagri","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2016.06.015_bib5","doi-asserted-by":"crossref","first-page":"e1002606","DOI":"10.1371\/journal.pgen.1002606","article-title":"The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development","volume":"8","author":"Benadiba","year":"2012","journal-title":"PLoS Genet."},{"key":"10.1016\/j.brainres.2016.06.015_bib6","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s12020-010-9366-9","article-title":"Abnormal hypothalamic oxytocin system in fibroblast growth factor 8-deficient mice","volume":"38","author":"Brooks","year":"2010","journal-title":"Endocrine"},{"key":"10.1016\/j.brainres.2016.06.015_bib7","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000312692","article-title":"Role of fibroblast growth factor signaling in gonadotropin-releasing hormone neuronal system development","volume":"39","author":"Chung","year":"2010","journal-title":"Front. Horm. Res."},{"key":"10.1016\/j.brainres.2016.06.015_bib8","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1002\/(SICI)1097-4695(20000605)43:3<234::AID-NEU2>3.0.CO;2-3","article-title":"Apoptosis during sexual differentiation of the bed nucleus of the stria terminalis in the rat brain","volume":"43","author":"Chung","year":"2000","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.brainres.2016.06.015_bib9","doi-asserted-by":"crossref","first-page":"4997","DOI":"10.1210\/en.2007-1634","article-title":"Fibroblast growth factor 8 signaling through fibroblast growth factor receptor 1 is required for the emergence of gonadotropin-releasing hormone neurons","volume":"149","author":"Chung","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.brainres.2016.06.015_bib10","article-title":"Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning","author":"Magnani","year":"2012","journal-title":"Cereb. Cortex"},{"issue":"1","key":"10.1016\/j.brainres.2016.06.015_bib11","first-page":"387","article-title":"Dendritic organization in the neurons of the visual and motor cortices of the cat","volume":"87","author":"Sholl","year":"1953","journal-title":"J. Anat."},{"key":"10.1016\/j.brainres.2016.06.015_bib12","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/ng1122","article-title":"Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome","volume":"33","author":"Dode","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2016.06.015_bib13","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.1172\/JCI34538","article-title":"Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice","volume":"118","author":"Falardeau","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainres.2016.06.015_bib14","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.tins.2015.02.007","article-title":"Contralateral targeting of the corpus callosum in normal and pathological brain function","volume":"38","author":"Fenlon","year":"2015","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.brainres.2016.06.015_bib15","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1093\/cercor\/bhs395","article-title":"Netrin-DCC signaling regulates corpus callosum formation through attraction of pioneering axons and by modulating Slit2-mediated repulsion","volume":"24","author":"Fothergill","year":"2014","journal-title":"Cereb. Cortex"},{"year":"2008","series-title":"The Mouse Brain in Stereotaxic Coordinates","author":"Franklin","key":"10.1016\/j.brainres.2016.06.015_bib16"},{"key":"10.1016\/j.brainres.2016.06.015_bib17","doi-asserted-by":"crossref","first-page":"8917","DOI":"10.1523\/JNEUROSCI.2086-04.2004","article-title":"Fgf8 regulates the development of intra-neocortical projections","volume":"24","author":"Huffman","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2016.06.015_bib18","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1002\/glia.22684","article-title":"The complex morphology of reactive astrocytes controlled by fibroblast growth factor signaling","volume":"62","author":"Kang","year":"2014","journal-title":"Glia"},{"key":"10.1016\/j.brainres.2016.06.015_bib19","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1159\/000082135","article-title":"Molecular signals regulating proliferation of stem and progenitor cells in mouse olfactory epithelium","volume":"26","author":"Kawauchi","year":"2004","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.brainres.2016.06.015_bib20","doi-asserted-by":"crossref","first-page":"5211","DOI":"10.1242\/dev.02143","article-title":"Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse","volume":"132","author":"Kawauchi","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.brainres.2016.06.015_bib21","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3389\/fnsyn.2014.00005","article-title":"The BDNF effects on dendritic spines of mature hippocampal neurons depend on neuronal activity","volume":"6","author":"Kellner","year":"2014","journal-title":"Front. Synaptic Neurosci."},{"key":"10.1016\/j.brainres.2016.06.015_bib22","doi-asserted-by":"crossref","first-page":"6608","DOI":"10.1523\/JNEUROSCI.14-11-06608.1994","article-title":"Axons of early generated neurons in cingulate cortex pioneer the corpus callosum","volume":"14","author":"Koester","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2016.06.015_bib23","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1212\/WNL.52.4.816","article-title":"Kallmann\u2019s syndrome: mirror movements associated with bilateral corticospinal tract hypertrophy","volume":"52","author":"Krams","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2016.06.015_bib24","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.brainres.2016.06.015_bib25","doi-asserted-by":"crossref","first-page":"E1709","DOI":"10.1210\/jc.2011-0454","article-title":"Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunction","volume":"96","author":"McCabe","year":"2011","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.brainres.2016.06.015_bib26","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/cyto.a.20022","article-title":"Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy images","volume":"58A","author":"Meijering","year":"2004","journal-title":"Cytom. Part A"},{"key":"10.1016\/j.brainres.2016.06.015_bib27","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1038\/ng0298-136","article-title":"An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination","volume":"18","author":"Meyers","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2016.06.015_bib28","doi-asserted-by":"crossref","first-page":"3645","DOI":"10.1002\/cne.22445","article-title":"Molecular regulation of the developing commissural plate","volume":"518","author":"Moldrich","year":"2010","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2016.06.015_bib29","doi-asserted-by":"crossref","first-page":"e10143","DOI":"10.1371\/journal.pone.0010143","article-title":"Differential fibroblast growth factor 8 (FGF8)-mediated autoregulation of its cognate receptors, Fgfr1 and Fgfr3, in neuronal cell lines","volume":"5","author":"Mott","year":"2010","journal-title":"PLOS One"},{"key":"10.1016\/j.brainres.2016.06.015_bib30","doi-asserted-by":"crossref","first-page":"149060","DOI":"10.1155\/2013\/149060","article-title":"Axon guidance mechanisms for establishment of callosal connections","volume":"2013","author":"Nishikimi","year":"2013","journal-title":"Neural Plast."},{"key":"10.1016\/j.brainres.2016.06.015_bib31","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1002\/(SICI)1097-4695(19980215)34:3<242::AID-NEU4>3.0.CO;2-2","article-title":"Cell death in the sexually dimorphic dorsal preoptic area\/anterior hypothalamus of perinatal male and female ferrets","volume":"34","author":"Park","year":"1998","journal-title":"J. Neurobiol."},{"issue":"Suppl. 1","key":"10.1016\/j.brainres.2016.06.015_bib32","article-title":"Neuropilin 1-Sema signaling regulates crossing of cingulate pioneering axons during development of the corpus callosum","volume":"19","author":"Piper","year":"2009","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.brainres.2016.06.015_bib33","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/cne.1170","article-title":"A role for cingulate pioneering axons in the development of the corpus callosum","volume":"434","author":"Rash","year":"2001","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2016.06.015_bib34","doi-asserted-by":"crossref","first-page":"10345","DOI":"10.1523\/JNEUROSCI.2787-07.2007","article-title":"Diffusion tensor magnetic resonance imaging and tract-tracing analysis of Probst bundle structure in Netrin1- and DCC-deficient mice","volume":"27","author":"Ren","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2016.06.015_bib35","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1399-0004.2004.00354.x","article-title":"Mechanisms regulating the development of the corpus callosum and its agenesis in mouse and human","volume":"66","author":"Richards","year":"2004","journal-title":"Clin. Genet."},{"key":"10.1016\/j.brainres.2016.06.015_bib36","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s12993-015-0081-9","article-title":"Fibroblast growth factor 8 regulates postnatal development of paraventricular nucleus neuroendocrine cells","volume":"11","author":"Rodriguez","year":"2015","journal-title":"Behav. Brain Funct."},{"key":"10.1016\/j.brainres.2016.06.015_bib37","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1523\/JNEUROSCI.23-01-00203.2003","article-title":"Abnormal development of forebrain midline glia and commissural projections in Nfia knock-out mice","volume":"23","author":"Shu","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2016.06.015_bib38","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1523\/JNEUROSCI.21-08-02749.2001","article-title":"Cortical axon guidance by the glial wedge during the development of the corpus callosum","volume":"21","author":"Shu","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2016.06.015_bib39","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1126\/science.6844928","article-title":"Postnatally induced formation of the corpus callosum in acallosal mice on glia-coated cellulose bridges","volume":"220","author":"Silver","year":"1983","journal-title":"Science"},{"key":"10.1016\/j.brainres.2016.06.015_bib40","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1002\/cne.903280308","article-title":"Immunocytochemical demonstration of early appearing astroglial structures that form boundaries and pathways along axon tracts in the fetal brain","volume":"328","author":"Silver","year":"1993","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2016.06.015_bib41","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/nn1705","article-title":"Midline radial glia translocation and corpus callosum formation require FGF signaling","volume":"9","author":"Smith","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainres.2016.06.015_bib42","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3389\/fendo.2013.00089","article-title":"Ontogenesis of gonadotropin-releasing hormone neurons: a model for hypothalamic neuroendocrine cell development","volume":"4","author":"Stevenson","year":"2013","journal-title":"Front Endocrinol."},{"key":"10.1016\/j.brainres.2016.06.015_bib43","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1242\/dev.02324","article-title":"Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers","volume":"133","author":"Storm","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.brainres.2016.06.015_bib44","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1073\/pnas.0337736100","article-title":"Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain","volume":"100","author":"Storm","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.brainres.2016.06.015_bib45","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1095\/biolreprod.111.095992","article-title":"Fibroblast growth factor signaling deficiencies impact female reproduction and kisspeptin neurons in mice","volume":"86","author":"Tata","year":"2012","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.brainres.2016.06.015_bib46","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1002\/(SICI)1096-8628(19980413)76:5<402::AID-AJMG7>3.0.CO;2-O","article-title":"CHARGE syndrome: report of 47 cases and review","volume":"76","author":"Tellier","year":"1998","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.brainres.2016.06.015_bib47","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ydbio.2005.10.020","article-title":"Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum","volume":"289","author":"Tole","year":"2006","journal-title":"Dev. Biol."},{"key":"10.1016\/j.brainres.2016.06.015_bib48","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1093\/cercor\/bhj178","article-title":"Neuroplasticity in human callosal dysgenesis: a diffusion tensor imaging study","volume":"17","author":"Tovar-Moll","year":"2007","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.brainres.2016.06.015_bib49","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.yfrne.2010.11.002","article-title":"Fibroblast growth factor signaling in the developing neuroendocrine hypothalamus","volume":"32","author":"Tsai","year":"2011","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.brainres.2016.06.015_bib50","doi-asserted-by":"crossref","first-page":"E2714","DOI":"10.1073\/pnas.1310233110","article-title":"Axon position within the corpus callosum determines contralateral cortical projection","volume":"110","author":"Zhou","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899316304395?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899316304395?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T18:00:11Z","timestamp":1757786411000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899316304395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":50,"alternative-id":["S0006899316304395"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2016.06.015","relation":{},"ISSN":["0006-8993"],"issn-type":[{"type":"print","value":"0006-8993"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Perinatal midline astrocyte development is impaired in fibroblast growth factor 8 hypomorphic mice","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2016.06.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}