{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:30:27Z","timestamp":1792143027205,"version":"4.4.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000026","name":"NIDA","doi-asserted-by":"publisher","award":["13936"],"award-info":[{"award-number":["13936"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"NIDA","doi-asserted-by":"publisher","award":["15119"],"award-info":[{"award-number":["15119"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"NIDA","doi-asserted-by":"publisher","award":["15947"],"award-info":[{"award-number":["15947"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.brainres.2016.07.044","type":"journal-article","created":{"date-parts":[[2016,7,31]],"date-time":"2016-07-31T07:14:50Z","timestamp":1469949290000},"page":"165-170","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"PB","title":["Nicotine produces long-term increases in cocaine reinforcement in adolescent but not adult rats"],"prefix":"10.1016","volume":"1654","author":[{"given":"Stephanie Collins","family":"Reed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sari","family":"Izenwasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2016.07.044_bib1","doi-asserted-by":"crossref","first-page":"460","DOI":"10.4062\/biomolther.2014.056","article-title":"Conditioned place preference and self-administration induced by nicotine in adolescent and adult rats","volume":"22","author":"Ahsan","year":"2014","journal-title":"Biomol. Ther."},{"key":"10.1016\/j.brainres.2016.07.044_bib2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.drugalcdep.2011.02.016","article-title":"Adolescent nicotine exposure sensitizes cue-induced reinstatement of cocaine seeking in rats bred for high and low saccharin intake","volume":"118","author":"Anker","year":"2011","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.brainres.2016.07.044_bib3","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1007\/s00213-002-1079-1","article-title":"Enhancement of cocaine-seeking behavior by repeated nicotine exposure in rats","volume":"162","author":"Bechtholt","year":"2002","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.brainres.2016.07.044_bib4","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1001\/archpsyc.1991.01810360033005","article-title":"Nicotine dependence, major depression, and anxiety in young adults","volume":"48","author":"Breslau","year":"1991","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainres.2016.07.044_bib5","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/BF02196920","article-title":"Psychiatric comorbidity of smoking and nicotine dependence","volume":"25","author":"Breslau","year":"1995","journal-title":"Behav. Genet"},{"key":"10.1016\/j.brainres.2016.07.044_bib6","doi-asserted-by":"crossref","DOI":"10.1093\/ntr\/ntw098","article-title":"Nicotine enhances footshock- and lithium chloride-conditioned place avoidance in male rats","author":"Buffalari","year":"2016","journal-title":"Nicotine Tob. Res."},{"key":"10.1016\/j.brainres.2016.07.044_bib7","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3389\/fncel.2015.00197","article-title":"Acute nicotine induces anxiety and disrupts temporal pattern organization of rat exploratory behavior in hole-board: a potential role for the lateral habenula","volume":"9","author":"Casarrubea","year":"2015","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.brainres.2016.07.044_bib8","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s00213-001-0935-8","article-title":"Neuronal nitric oxide synthase inhibition decreases cocaine self-administration behavior in rats","volume":"159","author":"Collins","year":"2002","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.brainres.2016.07.044_bib9","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.neuropharm.2003.09.024","article-title":"Chronic nicotine differentially alters cocaine-induced locomotor activity in adolescent vs. adult male and female rats","volume":"46","author":"Collins","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.brainres.2016.07.044_bib10","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.devbrainres.2004.08.004","article-title":"Nicotine treatment produces persistent increases in amphetamine-stimulated locomotor activity in periadolescent male but not female or adult male rats","volume":"153","author":"Collins","year":"2004","journal-title":"Dev. Brain Res."},{"key":"10.1016\/j.brainres.2016.07.044_bib11","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ejphar.2004.08.039","article-title":"Neurochemical alterations produced by daily nicotine exposure in periadolescent vs. adult male rats","volume":"502","author":"Collins","year":"2004","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.brainres.2016.07.044_bib12","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1002\/dev.21400","article-title":"Age differences in conditioned place preferences and taste aversions to nicotine","volume":"58","author":"Dannenhoffer","year":"2016","journal-title":"Dev. Psychobiol."},{"key":"10.1016\/j.brainres.2016.07.044_bib13","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1038\/npp.2011.8","article-title":"Nicotine alters limbic function in adolescent rat by a 5-HT1A receptor mechanism","volume":"36","author":"Dao","year":"2011","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainres.2016.07.044_bib14","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1369-1600.2012.00496.x","article-title":"Effects of adolescent nicotine exposure and withdrawal on intravenous cocaine self-administration during adulthood in male C57BL\/6J mice","volume":"19","author":"Dickson","year":"2014","journal-title":"Addict. Biol."},{"key":"10.1016\/j.brainres.2016.07.044_bib15","first-page":"2","article-title":"Impacts of early smoking initiation: long-term trends of lung cancer mortality and smoking initiation from repeated cross-sectional surveys in Great Britain","author":"Funatogawa","year":"2012","journal-title":"BMJ Open"},{"key":"10.1016\/j.brainres.2016.07.044_bib16","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/BF02245147","article-title":"Preexposure to amphetamine and nicotine predisposes rats to self-administer a low dose of cocaine","volume":"107","author":"Horger","year":"1992","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.brainres.2016.07.044_bib17","series-title":"Reducing Adolescent Risk: Toward an Integrated Approach","first-page":"335","article-title":"Alcohol, tobacco, and marijuana use among youth:\u00a0same-time and lagged and simultaneous-change associations in a nationally representative sample of 9- to 18-year-olds","author":"Hornik","year":"2003"},{"key":"10.1016\/j.brainres.2016.07.044_bib18","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s002130050049","article-title":"Evaluation of anti-cocaine antibodies and a cocaine vaccine in a rat self-administration model","volume":"148","author":"Kantak","year":"2000","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.brainres.2016.07.044_bib19","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1300\/J069v18n03_04","article-title":"Periadolescent nicotine exposure reduces cocaine reward in adult mice","volume":"18","author":"Kelley","year":"1999","journal-title":"J. Addict. Dis."},{"key":"10.1016\/j.brainres.2016.07.044_bib20","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1124\/pr.115.010967","article-title":"Mechanisms of action and persistent neuroplasticity by drugs of abuse","volume":"67","author":"Korpi","year":"2015","journal-title":"Pharm. Rev."},{"key":"10.1016\/j.brainres.2016.07.044_bib21","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.pbb.2015.02.019","article-title":"Sex differences in conditioned nicotine reward are age-specific","volume":"132","author":"Lenoir","year":"2015","journal-title":"Pharm. Biochem. Behav."},{"key":"10.1016\/j.brainres.2016.07.044_bib22","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.ntt.2007.02.002","article-title":"Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates","volume":"29","author":"Levin","year":"2007","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.brainres.2016.07.044_bib23","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1046\/j.1360-0443.1999.94691313.x","article-title":"Level of current and past adolescent cigarette smoking as predictors of future substance use disorders in young adulthood","volume":"94","author":"Lewinsohn","year":"1999","journal-title":"Addiction"},{"key":"10.1016\/j.brainres.2016.07.044_bib24","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ejphar.2005.01.002","article-title":"Periadolescent nicotine exposure causes heterologous sensitization to cocaine reinforcement","volume":"509","author":"McMillen","year":"2005","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.brainres.2016.07.044_bib25","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ntt.2006.10.012","article-title":"Low dose nicotine treatment during early adolescence increases subsequent cocaine reward","volume":"29","author":"McQuown","year":"2007","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.brainres.2016.07.044_bib26","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0376-8716(99)00034-4","article-title":"Cigarettes, alcohol, marijuana, other risk behaviors, and American youth","volume":"56","author":"Merrill","year":"1999","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.brainres.2016.07.044_bib27","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.bbr.2013.10.003","article-title":"Adolescence is a period of development characterized by short- and long-term vulnerability to the rewarding effects of nicotine and reduced sensitivity to the anorectic effects of this drug","volume":"257","author":"Natividad","year":"2013","journal-title":"Behav. Brain Res"},{"key":"10.1016\/j.brainres.2016.07.044_bib28","unstructured":"NSDUH, 2014. Substance Abuse and Mental Health Services Administration, Results from the 2013 National Survey on Drug Use and Health: Summary of National Findings, NSDUH Series H-48, HHS Publication No. (SMA) 14-4863, Substance Abuse and Mental Health Services Administration, Rockville, MD."},{"key":"10.1016\/j.brainres.2016.07.044_bib29","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/BF02244075","article-title":"Pre-exposure to amphetamine but not nicotine sensitizes rats to the motor activating effect of cocaine","volume":"103","author":"Schenk","year":"1991","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.brainres.2016.07.044_bib30","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ntt.2006.06.001","article-title":"A unique role for striatal serotonergic systems in the withdrawal from adolescent nicotine administration","volume":"29","author":"Slotkin","year":"2007","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.brainres.2016.07.044_bib31","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1159\/000207494","article-title":"Nicotine exposure in adolescence alters the response of serotonin systems to nicotine administered subsequently in adulthood","volume":"31","author":"Slotkin","year":"2009","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.brainres.2016.07.044_bib32","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0091-3057(92)90112-S","article-title":"Differential effects of injection regimen on behavioral responses to cocaine","volume":"41","author":"Terry","year":"1992","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.brainres.2016.07.044_bib33","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.pbb.2008.05.009","article-title":"Enhanced vulnerability to the rewarding effects of nicotine during the adolescent period of development","volume":"90","author":"Torres","year":"2008","journal-title":"Pharm. Biochem. Behav."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899316305352?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899316305352?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,10]],"date-time":"2018-09-10T04:21:16Z","timestamp":1536553276000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899316305352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":33,"alternative-id":["S0006899316305352"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2016.07.044","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nicotine produces long-term increases in cocaine reinforcement in adolescent but not adult rats","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2016.07.044","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}