{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T09:39:48Z","timestamp":1778319588668,"version":"3.51.4"},"reference-count":123,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.brainres.2017.12.037","type":"journal-article","created":{"date-parts":[[2017,12,27]],"date-time":"2017-12-27T13:31:31Z","timestamp":1514381491000},"page":"41-52","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Out of thin air: Hyperventilation-triggered seizures"],"prefix":"10.1016","volume":"1703","author":[{"given":"Kathryn A.","family":"Salvati","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark P.","family":"Beenhakker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2017.12.037_b0005","series-title":"Trait\u00e9 de l\u2019epilepsie: faisant le tome troisieme du Traite des nerfs et de leurs maladies","author":"Tissot","year":"1770"},{"key":"10.1016\/j.brainres.2017.12.037_b0010","first-page":"13","article-title":"The electroencephalogram in epilepsy and in conditions of impaired consciousness","volume":"34","author":"Gibbs","year":"1935","journal-title":"Arch. Neurol. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0015","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1528-1157.1989.tb05316.x","article-title":"Proposal for revised classification of epilepsies and epileptic syndromes","volume":"30","author":"ILAE","year":"1989","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2017.12.037_b0020","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1007\/s00415-004-0521-1","article-title":"Long-term prognosis for childhood and juvenile absence epilepsy","volume":"251","author":"Trinka","year":"2004","journal-title":"J. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0025","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.pediatrneurol.2013.10.009","article-title":"Current advances in childhood absence epilepsy","volume":"50","author":"Matricardi","year":"2014","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0030","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1212\/WNL.0000000000001971","article-title":"Long-term outcomes of generalized tonic-clonic seizures in a childhood absence epilepsy trial","volume":"85","author":"Shinnar","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2017.12.037_b0035","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1212\/WNL.45.8.1469","article-title":"Idiopathic generealized epilepsy of adolescence: are the syndromes clinically distinct?","volume":"45","author":"Reutens","year":"1995","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2017.12.037_b0040","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.seizure.2016.11.031","article-title":"Absence epilepsy: continuum of clinical presentation and epigenetics?","volume":"44","author":"Guilhoto","year":"2017","journal-title":"Seizure"},{"key":"10.1016\/j.brainres.2017.12.037_b0045","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S0370-4475(81)80072-X","article-title":"Individualization of so-called benign and functional epilepsy at different ages. Appraisal of variations corresponding the predisposition for epilepsy at these ages","volume":"11","author":"Gastaut","year":"1981","journal-title":"Rev. Electroencephalogr. Neurophysiol. Clin."},{"key":"10.1016\/j.brainres.2017.12.037_b0050","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1136\/jnnp.55.11.1002","article-title":"Typical absence seizures in adults: clinical, EEG, video-EEG findings and diagnostic\/syndromic considerations","volume":"55","author":"Panayiotopoulos","year":"1992","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.brainres.2017.12.037_b0055","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1136\/jnnp.61.5.471","article-title":"Electroclinical features of idiopathic generalised epilepsy with persisting absences in adult life","volume":"61","author":"Michelucci","year":"1996","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.brainres.2017.12.037_b0060","first-page":"198","article-title":"Absence status in adults","volume":"19","author":"Berkovic","year":"1983","journal-title":"Clin. Exp. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0065","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1136\/jnnp.74.2.192","article-title":"Idiopathic generalised epilepsy of adult onset: clinical syndromes and genetics","volume":"74","author":"Marini","year":"2003","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.brainres.2017.12.037_b0070","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1136\/jnnp.47.9.965","article-title":"Psychosis-like absence status of elderly patients: successful treatment with sodium valproate","volume":"47","author":"Iivanainen","year":"1984","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.brainres.2017.12.037_b0075","doi-asserted-by":"crossref","first-page":"135","DOI":"10.5698\/1535-7511-13.3.135","article-title":"The current state of absence epilepsy: can we have your attention?","volume":"13","author":"Tenney","year":"2013","journal-title":"Epilepsy Curr."},{"key":"10.1016\/j.brainres.2017.12.037_b0080","article-title":"Pathophysiology of absence epilepsy: insights from genetic models","author":"Depaulis","year":"2017","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2017.12.037_b0085","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jneumeth.2015.05.022","article-title":"The genetic absence epilepsy rat from Strasbourg as a model to decipher the neuronal and network mechanisms of generalized idiopathic epilepsies","volume":"260","author":"Depaulis","year":"2016","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.brainres.2017.12.037_b0090","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1023\/A:1019807719343","article-title":"Insights from mouse models of absence epilepsy into Ca2+ channel physiology and disease etiology","volume":"22","author":"Felix","year":"2002","journal-title":"Cell Mol. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0095","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jneumeth.2015.08.034","article-title":"Acute and chronic pharmacological models of generalized absence seizures","volume":"260","author":"Cortez","year":"2016","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.brainres.2017.12.037_b0100","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1023\/A:1026179013847","article-title":"Genetic animal models for absence epilepsy: a review of the WAG\/Rij strain of rats","volume":"33","author":"Coenen","year":"2003","journal-title":"Behav. Genet."},{"key":"10.1016\/j.brainres.2017.12.037_b0105","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S1471-4892(02)00015-2","article-title":"GABAA receptor function and pharmacology in epilepsy and status epilepticus","volume":"3","author":"Jones-Davis","year":"2003","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.brainres.2017.12.037_b0110","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1113\/jphysiol.2010.186999","article-title":"Mutations in GABAA receptor subunits associated with genetic epilepsies","volume":"588","author":"Macdonald","year":"2010","journal-title":"J. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0115","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/S0165-6147(00)01646-1","article-title":"GABAA receptor subtypes: dissecting their pharmacological functions","volume":"22","author":"Rudolph","year":"2001","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.brainres.2017.12.037_b0120","doi-asserted-by":"crossref","first-page":"17536","DOI":"10.1073\/pnas.0708440104","article-title":"Reduced cortical inhibition in a mouse model of familial childhood absence epilepsy","volume":"104","author":"Tan","year":"2007","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.brainres.2017.12.037_b0125","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/ng885","article-title":"Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy","volume":"31","author":"Cossette","year":"2002","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2017.12.037_b0130","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1460-9568.2011.07767.x","article-title":"Novel \u03b11 and \u03b32 GABAA receptor subunit mutations in families with idiopathic generalized epilepsy","volume":"34","author":"Lachance-Touchette","year":"2011","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0135","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1002\/ana.20874","article-title":"A mutation in the GABAA receptor \u03b11-subunit is associated with absence epilepsy","volume":"59","author":"Maljevic","year":"2006","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0140","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1126\/science.283.5401.541","article-title":"Reciprocal inhibitory connections and network synchrony in the mammalian thalamus","volume":"283","author":"Huntsman","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.brainres.2017.12.037_b0145","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.neulet.2010.08.001","article-title":"Altered GABAA receptor subunit expression and pharmacology in human Angelman syndrome cortex","volume":"483","author":"Roden","year":"2010","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2017.12.037_b0150","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/1531-8249(200101)49:1<110::AID-ANA17>3.0.CO;2-T","article-title":"Decreased binding of [11C]flumazenil in Angelman syndrome patients with GABAA receptor \u03b23 subunit deletions","volume":"49","author":"Holopainen","year":"2001","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0155","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/ana.10607","article-title":"Association between genetic variation of CACNA1H and childhood absence epilepsy","volume":"54","author":"Chen","year":"2003","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0160","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1002\/ana.21169","article-title":"Extended spectrum of idiopathic generalized epilepsies associated with CACNA1H functional variants","volume":"62","author":"Heron","year":"2007","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0165","doi-asserted-by":"crossref","first-page":"9681","DOI":"10.1074\/jbc.C400006200","article-title":"Gating effects of mutations in the Cav3.2 T-type calcium channel associated with childhood absence epilepsy","volume":"279","author":"Khosravani","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainres.2017.12.037_b0170","doi-asserted-by":"crossref","first-page":"4844","DOI":"10.1523\/JNEUROSCI.0847-05.2005","article-title":"Functional characterization and neuronal modeling of the effects of childhood absence epilepsy variants of CACNA1H, a T-type calcium channel","volume":"25","author":"Vitko","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0175","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.1528-1167.2006.00482.x","article-title":"Functional analysis of Cav3.2 T-type calcium channel mutations linked to childhood absence epilepsy","volume":"47","author":"Peloquin","year":"2006","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2017.12.037_b0180","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1101\/gad.260869.115","article-title":"CaV3.2 calcium channels control NMDA receptor-mediated transmission: a new mechanism for absence epilepsy","volume":"29","author":"Wang","year":"2015","journal-title":"Genes Dev."},{"key":"10.1016\/j.brainres.2017.12.037_b0185","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/nn.3947","article-title":"Molecular mechanisms of epilepsy","volume":"18","author":"Staley","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0190","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1002\/ana.410130610","article-title":"Long-term prognosis in two forms of childhood epilepsy: typical absence seizures and epilepsy with rolandic (centrotemporal) EEG foci","volume":"13","author":"Loiseau","year":"1983","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0195","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1212\/WNL.47.4.912","article-title":"Long-term prognosis of typical childhood absence epilepsy: remission or progression to juvenile myoclonic epilepsy","volume":"47","author":"Wirrell","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2017.12.037_b0200","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1056\/NEJM199806113382402","article-title":"Long-term prognosis of seizures with onset in childhood","volume":"338","author":"Sillanp\u00e4\u00e4","year":"1998","journal-title":"New Engl. J. Med."},{"key":"10.1016\/j.brainres.2017.12.037_b0205","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/epi.12028","article-title":"Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: initial monotherapy outcomes at 12 months","volume":"54","author":"Glauser","year":"2013","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2017.12.037_b0210","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1001\/archpedi.1997.02170390042008","article-title":"Long-term psychosocial outcome in typical absence epilepsy: sometimes a wolf in sheeps clothing","volume":"151","author":"Wirrell","year":"1997","journal-title":"Arch. Pediatr. Adolesc. Med."},{"key":"10.1016\/j.brainres.2017.12.037_b0215","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1111\/j.1528-1167.2008.01680.x","article-title":"Childhood absence epilepsy: behavioral, cognitive, and linguistic comorbidities","volume":"49","author":"Caplan","year":"2008","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2017.12.037_b0220","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1111\/epi.13197","article-title":"A call to arms against \u201cthe phantom of epilepsy\u201d","volume":"56","author":"Caplan","year":"2015","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2017.12.037_b0225","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1136\/adc.81.4.351","article-title":"Typical absence seizures and their treatment","volume":"81","author":"Panayiotopoulos","year":"1999","journal-title":"Arch. Dis. Child"},{"key":"10.1016\/j.brainres.2017.12.037_b0230","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.pediatrneurol.2014.12.003","article-title":"Hyperventilation during routine electroencephalography: are three minutes really necessary?","volume":"52","author":"Watemberg","year":"2015","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0235","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1177\/155005949502600405","article-title":"Qualitative and quantitative abnormalities of breath counting during brief generalized 3\u202fHz spike and slow wave 'subclinical' discharges","volume":"26","author":"Giannakodimos","year":"1995","journal-title":"Clin. Electroencephalogr."},{"key":"10.1016\/j.brainres.2017.12.037_b0240","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1212\/WNL.31.9.1175","article-title":"Hyperventilation and 6-hour EEG recording in evaluation of absence seizures","volume":"31","author":"Adams","year":"1981","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2017.12.037_b0245","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1542\/peds.30.6.893","article-title":"Petit mal epilepsy","volume":"30","author":"Holowach","year":"1962","journal-title":"Pediatrics"},{"key":"10.1016\/j.brainres.2017.12.037_b0250","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1001\/archneurpsyc.1940.02280020070005","article-title":"Adjustment of acid-base balance of patients with petit mal epilepsy to overventilation","volume":"43","author":"Nims","year":"1940","journal-title":"Arch. Neurol. Psychiatry"},{"key":"10.1016\/j.brainres.2017.12.037_b0255","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1046\/j.1528-1157.2002.35101.x","article-title":"Hyperventilation-induced high-amplitude rhythmic slowing with altered awareness: a video-EEG comparison with absence seizures","volume":"43","author":"Lum","year":"2002","journal-title":"Epilepsia (Series 4)"},{"key":"10.1016\/j.brainres.2017.12.037_b0260","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1001\/archneurpsyc.1942.02290060017001","article-title":"Regulation of cerebral carbon dioxide","volume":"47","author":"Gibbs","year":"1942","journal-title":"Arch. Neurol. Psychiatry"},{"key":"10.1016\/j.brainres.2017.12.037_b0265","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0013-4694(91)90050-E","article-title":"Physical exercise and voluntary hyperventilation in childhood absence epilepsy","volume":"79","author":"Esquivel","year":"1991","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0270","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1161\/01.STR.8.3.358","article-title":"Analysis of vasoactivity of local pH, PCO2 and bicarbonate on pial vessels","volume":"8","author":"Kontos","year":"1977","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2017.12.037_b0275","unstructured":"Cipolla, M.J., 2009. In: The Cerebral Circulation. San Rafael (Ch. 5)."},{"key":"10.1016\/j.brainres.2017.12.037_b0280","series-title":"Medical Physiology","author":"Boron","year":"2009"},{"key":"10.1016\/j.brainres.2017.12.037_b0285","doi-asserted-by":"crossref","first-page":"E1387","DOI":"10.1073\/pnas.1121359109","article-title":"Inversion of neurovascular coupling by subarachnoid blood depends on large-conductance Ca2+-activated K+ (BK) channels","volume":"109","author":"Koide","year":"2012","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.brainres.2017.12.037_b0290","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1126\/science.1216283","article-title":"Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function","volume":"336","author":"Sonkusare","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.brainres.2017.12.037_b0295","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1001\/archneurpsyc.1940.02280020031003","article-title":"Variations in the cabon dioxide content of the blood in epilepsy","volume":"43","author":"Gibbs","year":"1940","journal-title":"Arch. Neurol. Psychiatry"},{"key":"10.1016\/j.brainres.2017.12.037_b0300","first-page":"6","article-title":"The effect on epileptic seizures of varying composition of respired air","volume":"6","author":"Lennox","year":"1928","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainres.2017.12.037_b0305","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.eplepsyres.2013.11.012","article-title":"5% CO2 inhalation suppresses hyperventilation-induced absence seizures in children","volume":"108","author":"Yang","year":"2014","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.brainres.2017.12.037_b0310","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1111\/j.1528-1167.2012.03421.x","article-title":"A brief history on the oscillating roles of thalamus and cortex in absence seizures","volume":"53","author":"Avoli","year":"2012","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainres.2017.12.037_b0315","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1001\/archneurpsyc.1941.02280180015001","article-title":"Electroencephalographic classification of the epilepsies","volume":"45","author":"Jasper","year":"1941","journal-title":"Arch. Neurol. Psychiatry"},{"key":"10.1016\/j.brainres.2017.12.037_b0320","series-title":"Epilepsy and Cerebral Localization","author":"Penfield","year":"1941"},{"key":"10.1016\/j.brainres.2017.12.037_b0325","volume":"Vol. 1","author":"Jones","year":"2007"},{"key":"10.1016\/j.brainres.2017.12.037_b0330","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1152\/physrev.1988.68.3.649","article-title":"The functional states of the thalamus and the associated neuronal interplay","volume":"68","author":"Steriade","year":"1988","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.brainres.2017.12.037_b0335","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1146\/annurev.neuro.20.1.185","article-title":"SLEEP AND AROUSAL: thalamocortical mechanisms","volume":"20","author":"McCormick","year":"1997","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0340","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1152\/ajplegacy.1941.135.2.301","article-title":"The interaction of certain spontaneous and induced cortical potentials","volume":"135","author":"Dempsey","year":"1942","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0345","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1152\/ajplegacy.1941.135.2.293","article-title":"The production of rhythmically recurrent cortical potentials after localized thalamic stimulation","volume":"135","author":"Dempsey","year":"1942","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0350","article-title":"Mechanism of thalamocortical augmentation and repetition","author":"Morison","year":"1942","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0355","first-page":"272","article-title":"Experimental studies of the functional anatomy of petit mal epilepsy","volume":"26","author":"Jasper","year":"1947","journal-title":"Res. Publ. Assoc. Res. Nerve Ment. Dis."},{"key":"10.1016\/j.brainres.2017.12.037_b0360","first-page":"305","article-title":"Effects of thalamic stimulation in unanaesthetised animals: the arrest reaction and petit Mal-like seizures, activation patterns and generalized convulsions","volume":"1","author":"Hunter","year":"1949","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0365","article-title":"Independence of diffuse thalamocortical projection system shown by specific nuclear destructions","volume":"252\u2013271","author":"Hanbery","year":"1953","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0370","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/0013-4694(77)90279-6","article-title":"Spike-wave rhythms in cat cortex induced by parenteral penicillin I. Electroencephalographic features","volume":"42","author":"Fisher","year":"1977","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0375","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/0014-4886(82)90252-7","article-title":"Role of the thalamus in generalized penicillin epilepsy: observations on decorticated cats","volume":"77","author":"Avoli","year":"1982","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0380","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/0014-4886(82)90112-1","article-title":"Interaction of cortex and thalamus in spike and wave discharges of feline generalized penicillin epilepsy","volume":"76","author":"Avoli","year":"1982","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0385","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1152\/jn.1983.50.4.819","article-title":"An analysis of penicillin-induced generalized spike and wave discharges using simultaneous recordings of cortical and thalamic single neurons","volume":"50","author":"Avoli","year":"1983","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0390","first-page":"309","article-title":"\u201cCentrencephalic\u201d spike wave discharges following parenteral penicillin injection in the cat","volume":"19","author":"Prince","year":"1969","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2017.12.037_b0395","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.neuroscience.2016.02.070","article-title":"Timing of high-frequency cortical stimulation in a genetic absence model","volume":"324","author":"van Heukelum","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2017.12.037_b0400","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0304-3940(86)90586-0","article-title":"Two types of electrocortical paroxysms in an inbred strain of rats","volume":"70","author":"van Luijtelaar","year":"1986","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2017.12.037_b0405","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0006-8993(70)90361-6","article-title":"Organization of specific-nonspecific thalamic internuclear synaptic pathways","volume":"21","author":"Desiraju","year":"1970","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2017.12.037_b0410","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1152\/jn.1962.25.5.621","article-title":"Intracellular recording from thalamic neurons during recruiting responses","volume":"25","author":"Purpura","year":"1962","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0415","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.pneurobio.2005.01.002","article-title":"The reticular nucleus revisited: Intrinsic and network properties of a thalamic pacemaker","volume":"75","author":"Fuentealba","year":"2005","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0420","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0014-2999(97)01085-6","article-title":"Opposite effects of GABAB receptor antagonists on absences and convulsive seizures","volume":"332","author":"Vergnes","year":"1997","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.brainres.2017.12.037_b0425","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/0013-4694(65)90077-5","article-title":"Differentional effects of hyperventilation on the excitability of intact and isolated cortex","volume":"18","author":"Sherwin","year":"1965","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0430","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/0013-4694(67)90019-3","article-title":"Alterations in the non-specific cortical afference during hypervenitlation","volume":"23","author":"Sherwin","year":"1967","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0435","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1113\/jphysiol.1984.sp015153","article-title":"Electrophysiological properties of guinea-pig thalamic neurones: an in vitro study","volume":"349","author":"Jahnsen","year":"1984","journal-title":"J. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0440","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1038\/297406a0","article-title":"Electrophysiology of mammalian thalamic neurones in vitro","volume":"297","author":"Llin\u00e1s","year":"1982","journal-title":"Nature"},{"key":"10.1016\/j.brainres.2017.12.037_b0445","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1126\/science.8235588","article-title":"Thalamocortical oscillations in the sleeping and aroused brain","volume":"262","author":"Steriade","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.brainres.2017.12.037_b0450","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1126\/science.274.5288.771","article-title":"Control of spatiotemporal coherence of a thalamic oscillation by corticothalamic feedback","volume":"274","author":"Contreras","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.brainres.2017.12.037_b0455","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1152\/jn.1998.79.2.999","article-title":"Mechanisms underlying the synchronizing action of corticothalamic feedback through inhibition of thalamic relay cells","volume":"79","author":"Destexhe","year":"1998","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0460","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1152\/jn.1996.76.3.1367","article-title":"Functional organization of thalamocortical relays","volume":"76","author":"Sherman","year":"1996","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0465","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1113\/jphysiol.1995.sp020613","article-title":"Role of the ferret perigeniculate nucleus in the generation of synchronized oscillations in vitro","volume":"483","author":"Bal","year":"1995","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/j.brainres.2017.12.037_b0470","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1152\/jn.1992.68.4.1373","article-title":"Simulation of the currents involved in rhythmic oscillations in thalamic relay neurons","volume":"68","author":"Huguenard","year":"1992","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0475","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1152\/jn.1992.68.4.1384","article-title":"A model of the electrophysiological properties of thalamocortical relay neurons","volume":"68","author":"McCormick","year":"1992","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0480","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.neuron.2009.05.015","article-title":"Neurons that fire together also conspire together: is normal sleep circuitry hijacked to generate epilepsy?","volume":"62","author":"Beenhakker","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2017.12.037_b0485","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.tins.2007.05.007","article-title":"Thalamic synchrony and dynamic regulation of global forebrain oscillations","volume":"30","author":"Huguenard","year":"2007","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0490","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1146\/annurev.physiol.63.1.815","article-title":"On the cellular and network bases of epileptic seizures","volume":"63","author":"McCormick","year":"2001","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0495","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.neuron.2016.10.024","article-title":"Tapping the brakes: cellular and synaptic mechanisms that regulate thalamic oscillations","volume":"92","author":"Fogerson","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2017.12.037_b0500","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/cne.10738","article-title":"Structure and connections of the thalamic reticular nucleus: advancing views over half a century","volume":"463","author":"Guillery","year":"2003","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0505","doi-asserted-by":"crossref","first-page":"5153","DOI":"10.1523\/JNEUROSCI.20-13-05153.2000","article-title":"Corticothalamic inputs control the pattern of activity generated in thalamocortical networks","volume":"20","author":"Blumenfeld","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0510","volume":"vol. 353","author":"Llin\u00e1s","year":"1998","journal-title":"The Neuronal Basis for Consciousness."},{"key":"10.1016\/j.brainres.2017.12.037_b0515","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1523\/JNEUROSCI.15-01-00623.1995","article-title":"Relations between cortical and thalamic cellular events during transition from sleep patterns to paroxysmal activity","volume":"15","author":"Steriade","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0520","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1113\/jphysiol.1984.sp015154","article-title":"Ionic basis for the electro-responsiveness and oscillatory properties of guinea-pig thalamic neurones in vitro","volume":"349","author":"Jahnsen","year":"1984","journal-title":"J. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0525","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2014.00045","article-title":"The tole of T-type calcium channel genes in absence seizures","volume":"5","author":"Chen","year":"2014","journal-title":"Front. Neurol."},{"key":"10.1016\/j.brainres.2017.12.037_b0530","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1007\/s00424-014-1461-y","article-title":"T-type Ca2+ channels in absence epilepsy","volume":"466","author":"Cheong","year":"2014","journal-title":"Pflugers Arch. \u2013 Eur. J. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0535","doi-asserted-by":"crossref","first-page":"7839","DOI":"10.1073\/pnas.1420983112","article-title":"Altered thalamocortical rhythmicity and connectivity in mice lacking CaV3.1 T-type Ca2+ channels in unconsciousness","volume":"112","author":"Choi","year":"2015","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.brainres.2017.12.037_b0540","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.19-18-j0005.1999","article-title":"Neocortical synchronized oscillations induced by thalamic disinhibition in vivo","volume":"19","author":"Castro-Alamancos","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0545","doi-asserted-by":"crossref","first-page":"10599","DOI":"10.1523\/JNEUROSCI.2732-08.2008","article-title":"Loss of inhibitory neuron AMPA receptors contributes to ataxia and epilepsy in Stargazer mice","volume":"28","author":"Menuz","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0550","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1038\/nn.2896","article-title":"A new mode of corticothalamic transmission revealed in the Gria4\u2212\/\u2212 model of absence epilepsy","volume":"14","author":"Paz","year":"2011","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0555","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1113\/jphysiol.1991.sp018745","article-title":"Two inward currents and the transformation of low-frequency oscillations of rat and cat thalamocortical cells","volume":"441","author":"Soltesz","year":"1991","journal-title":"J. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0560","volume":"Vol. 96","author":"Meuth","year":"2006","journal-title":"Membrane Resting Potential of Thalamocortical Relay Neurons Is Shaped by the Interaction Among TASK3 and HCN2 Channels"},{"key":"10.1016\/j.brainres.2017.12.037_b0565","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1152\/physrev.00029.2008","article-title":"Hyperpolarization-activated cation channels: from genes to function","volume":"89","author":"Biel","year":"2009","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.brainres.2017.12.037_b0570","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1096\/fj.04-3300com","article-title":"Evidence that aquaporin 1 is a major pathway for CO2 transport across the human erythrocyte membrane","volume":"20","author":"Endeward","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.brainres.2017.12.037_b0575","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.bbapap.2009.10.021","article-title":"Evaluating the role of carbonic anhydrases in the transport of HCO3\u2212-related species","volume":"1804","author":"Boron","year":"2010","journal-title":"Biochim. Biophys. Acta (BBA)"},{"key":"10.1016\/j.brainres.2017.12.037_b0580","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1002\/glia.10187","article-title":"Surface carbonic anhydrase activity on astrocytes and neurons facilitates lactate transport","volume":"41","author":"Svichar","year":"2003","journal-title":"Glia"},{"key":"10.1016\/j.brainres.2017.12.037_b0585","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2007"},{"key":"10.1016\/j.brainres.2017.12.037_b0590","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1113\/jphysiol.1936.sp003427","article-title":"The spread of activity in the cerebral cortex","volume":"88","author":"Adrian","year":"1939","journal-title":"J. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0595","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/jn.1951.14.1.1","article-title":"Dendritic potential of cortical neurons produced by direct electrical stimulation of the cerebral cortex","volume":"14","author":"Chang","year":"1951","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0600","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1113\/jphysiol.1950.sp004463","article-title":"Some properties of the cat's isolated cortex","volume":"111","author":"Burns","year":"1950","journal-title":"J. Physiol."},{"key":"10.1016\/j.brainres.2017.12.037_b0605","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1523\/JNEUROSCI.20-05-01735.2000","article-title":"Reciprocal inhibitory connections regulate the spatiotemporal properties of intrathalamic oscillations","volume":"20","author":"Sohal","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2017.12.037_b0610","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1126\/science.278.5335.130","article-title":"Functional dynamics of GABAergic inhibition in the thalamus","volume":"278","author":"Kim","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.brainres.2017.12.037_b0615","doi-asserted-by":"crossref","first-page":"8880","DOI":"10.1523\/JNEUROSCI.17-22-08880.1997","article-title":"Functional properties of perigeniculate inhibition of dorsal lateral geniculate nucleus thalamocortical neurons in vitro","volume":"17","author":"Sanchez-Vives","year":"1997","journal-title":"J. Neurosci."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899317305796?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899317305796?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T17:58:56Z","timestamp":1757786336000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899317305796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":123,"alternative-id":["S0006899317305796"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2017.12.037","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Out of thin air: Hyperventilation-triggered seizures","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2017.12.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}