{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T22:16:17Z","timestamp":1788387377248,"version":"build-2803163510"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"JSPS KAKENHI","doi-asserted-by":"publisher","award":["15K10365"],"award-info":[{"award-number":["15K10365"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"JSPS KAKENHI","doi-asserted-by":"publisher","award":["16K10730"],"award-info":[{"award-number":["16K10730"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"JSPS KAKENHI","doi-asserted-by":"publisher","award":["17K10901"],"award-info":[{"award-number":["17K10901"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"JSPS KAKENHI","doi-asserted-by":"publisher","award":["17K01513"],"award-info":[{"award-number":["17K01513"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.brainres.2018.05.033","type":"journal-article","created":{"date-parts":[[2018,5,24]],"date-time":"2018-05-24T00:56:02Z","timestamp":1527123362000},"page":"37-44","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Preservation of interhemispheric cortical connections through corpus callosum following intravenous infusion of mesenchymal stem cells in a rat model of cerebral infarction"],"prefix":"10.1016","volume":"1695","author":[{"given":"Hiroshi","family":"Nagahama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahito","family":"Nakazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7961-9698","authenticated-orcid":false,"given":"Masanori","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Kataoka-Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Namioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Namioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Oka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rie","family":"Onodera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junpei","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffery D.","family":"Kocsis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Honmou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2018.05.033_b0005","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3389\/fneur.2015.00155","article-title":"The dark side of the force \u2013 constraints and complications of cell therapies for stroke","volume":"6","author":"Boltze","year":"2015","journal-title":"Front. Neurol."},{"key":"10.1016\/j.brainres.2018.05.033_b0010","doi-asserted-by":"crossref","first-page":"6196","DOI":"10.1523\/JNEUROSCI.5852-08.2009","article-title":"Motor cortex bilateral motor representation depends on subcortical and interhemispheric interactions","volume":"29","author":"Brus-Ramer","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2018.05.033_b0015","doi-asserted-by":"crossref","first-page":"6062","DOI":"10.1523\/JNEUROSCI.22-14-06062.2002","article-title":"Synchronous neuronal activity is a signal for axonal sprouting after cortical lesions in the adult","volume":"22","author":"Carmichael","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2018.05.033_b0020","doi-asserted-by":"crossref","first-page":"74537","DOI":"10.18632\/oncotarget.12902","article-title":"Intravenous administration of xenogenic adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes markedly reduced brain infarct volume and preserved neurological function in rat after acute ischemic stroke","volume":"7","author":"Chen","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.brainres.2018.05.033_b0025","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/scrt544","article-title":"The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity","volume":"6","author":"Cui","year":"2015","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.brainres.2018.05.033_b0030","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1038\/jcbfm.2013.50","article-title":"The sonic hedgehog pathway mediates brain plasticity and subsequent functional recovery after bone marrow stromal cell treatment of stroke in mice","volume":"33","author":"Ding","year":"2013","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainres.2018.05.033_b0035","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.expneurol.2005.05.004","article-title":"Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat","volume":"199","author":"Honma","year":"2006","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2018.05.033_b0040","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1093\/brain\/awr063","article-title":"Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke","volume":"134","author":"Honmou","year":"2011","journal-title":"Brain"},{"key":"10.1016\/j.brainres.2018.05.033_b0045","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.molmed.2012.02.003","article-title":"Mesenchymal stem cells: therapeutic outlook for stroke","volume":"18","author":"Honmou","year":"2012","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.brainres.2018.05.033_b0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2003.09.084","article-title":"A therapeutic window for intravenous administration of autologous bone marrow after cerebral ischemia in adult rats","volume":"1007","author":"Iihoshi","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2018.05.033_b0055","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1089\/neu.2013.3238","article-title":"Diffusion tensor imaging as a predictor of locomotor function after experimental spinal cord injury and recovery","volume":"31","author":"Kelley","year":"2014","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2018.05.033_b0060","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/B978-0-444-59544-7.00005-6","article-title":"Bone marrow stem cells in experimental stroke","volume":"201","author":"Kocsis","year":"2012","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.brainres.2018.05.033_b0065","doi-asserted-by":"crossref","first-page":"e0122615","DOI":"10.1371\/journal.pone.0122615","article-title":"The microstructural status of the corpus callosum is associated with the degree of motor function and neurological deficit in stroke patients","volume":"10","author":"Li","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.brainres.2018.05.033_b0070","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1161\/STROKEAHA.114.007044","article-title":"Enhanced interhemispheric functional connectivity compensates for anatomical connection damages in subcortical stroke","volume":"46","author":"Liu","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2018.05.033_b0075","doi-asserted-by":"crossref","first-page":"2546","DOI":"10.1161\/STROKEAHA.109.547265","article-title":"Remodeling of the corticospinal innervation and spontaneous behavioral recovery after ischemic stroke in adult mice","volume":"40","author":"Liu","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2018.05.033_b0080","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.3727\/096368916X691132","article-title":"intravenous injection of clinical grade human MSCs after experimental stroke: functional benefit and microvascular effect","volume":"25","author":"Moisan","year":"2016","journal-title":"Cell Transplant."},{"key":"10.1016\/j.brainres.2018.05.033_b0085","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.neuroscience.2016.08.037","article-title":"Intravenous infusion of mesenchymal stem cells promotes functional recovery in a model of chronic spinal cord injury","volume":"335","author":"Morita","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2018.05.033_b0090","article-title":"Elevated brain derived neurotrophic factor (BDNF) levels in plasma but not serum reflect in vivo functional viability of infused mesenchymal stem cells after middle cerebral artery occlusion in rat","author":"Nakamura","year":"2017","journal-title":"J. Neurosurg. Sci."},{"key":"10.1016\/j.brainres.2018.05.033_b0095","doi-asserted-by":"crossref","first-page":"917","DOI":"10.3171\/2016.8.JNS16240","article-title":"Intravenous infusion of mesenchymal stem cells inhibits intracranial hemorrhage after recombinant tissue plasminogen activator therapy for transient middle cerebral artery occlusion in rats","volume":"127","author":"Nakazaki","year":"2017","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainres.2018.05.033_b0100","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.neuroimage.2014.04.001","article-title":"Waxholm space atlas of the sprague dawley rat brain","volume":"97","author":"Papp","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.brainres.2018.05.033_b0105","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2007"},{"key":"10.1016\/j.brainres.2018.05.033_b0110","doi-asserted-by":"crossref","first-page":"51","DOI":"10.5966\/sctm.2011-0019","article-title":"Concise review: mesenchymal stem cells and translational medicine: emerging issues","volume":"1","author":"Ren","year":"2012","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.brainres.2018.05.033_b0115","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/978-1-60327-931-4_13","article-title":"A rat middle cerebral artery occlusion model and intravenous cellular delivery","volume":"549","author":"Sasaki","year":"2009","journal-title":"Meth. Mol. Biol."},{"key":"10.1016\/j.brainres.2018.05.033_b0120","doi-asserted-by":"crossref","first-page":"14932","DOI":"10.1523\/JNEUROSCI.2769-09.2009","article-title":"BDNF-hypersecreting human mesenchymal stem cells promote functional recovery, axonal sprouting, and protection of corticospinal neurons after spinal cord injury","volume":"29","author":"Sasaki","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2018.05.033_b0125","doi-asserted-by":"crossref","first-page":"e26577","DOI":"10.1371\/journal.pone.0026577","article-title":"Development of a middle cerebral artery occlusion model in the nonhuman primate and a safety study of i.v. infusion of human mesenchymal stem cells","volume":"6","author":"Sasaki","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.brainres.2018.05.033_b0130","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.2522\/ptj.20150504","article-title":"Synergic effects of rehabilitation and intravenous infusion of mesenchymal stem cells after stroke in rats","volume":"96","author":"Sasaki","year":"2016","journal-title":"Phys. Ther."},{"key":"10.1016\/j.brainres.2018.05.033_b0135","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0001-15.2015","article-title":"3D imaging of axons in transparent spinal cords from rodents and nonhuman primates","volume":"2","author":"Soderblom","year":"2015","journal-title":"eNeuro"},{"key":"10.1016\/j.brainres.2018.05.033_b0140","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.brainres.2012.12.028","article-title":"Bilateral cortical hyperactivity detected by fMRI associates with improved motor function following intravenous infusion of mesenchymal stem cells in a rat stroke model","volume":"1497","author":"Suzuki","year":"2013","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2018.05.033_b0145","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1161\/STROKEAHA.116.012701","article-title":"Systematic review and meta-analysis of bone marrow-derived mononuclear cells in animal models of ischemic stroke","volume":"47","author":"Vahidy","year":"2016","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2018.05.033_b0150","doi-asserted-by":"crossref","first-page":"110","DOI":"10.3389\/fncir.2014.00110","article-title":"Simultaneous visualization of extrinsic and intrinsic axon collaterals in Golgi-like detail for mouse corticothalamic and corticocortical cells: a double viral infection method","volume":"8","author":"Watakabe","year":"2014","journal-title":"Front. Neural Circuits"},{"key":"10.1016\/j.brainres.2018.05.033_b0155","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/j.neuroimage.2008.03.036","article-title":"Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers","volume":"41","author":"Wedeen","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.brainres.2018.05.033_b0160","doi-asserted-by":"crossref","first-page":"22221","DOI":"10.3390\/ijms141122221","article-title":"Combination BMSC and Niaspan treatment of stroke enhances white matter remodeling and synaptic protein expression in diabetic rats","volume":"14","author":"Ye","year":"2013","journal-title":"Int. J. Mol. Sci."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899318302907?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899318302907?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T10:09:27Z","timestamp":1604311767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899318302907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":32,"alternative-id":["S0006899318302907"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2018.05.033","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preservation of interhemispheric cortical connections through corpus callosum following intravenous infusion of mesenchymal stem cells in a rat model of cerebral infarction","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2018.05.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}