{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T07:46:20Z","timestamp":1779090380590,"version":"3.51.4"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.brainres.2020.147066","type":"journal-article","created":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T12:16:09Z","timestamp":1597666569000},"page":"147066","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Loss of tyrosine hydroxylase, motor deficits and elevated iron in a mouse model of phospholipase A2G6-associated neurodegeneration (PLAN)"],"prefix":"10.1016","volume":"1748","author":[{"given":"Michael","family":"Minkley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"MacLeod","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher K.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raad","family":"Nashmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1254-4086","authenticated-orcid":false,"given":"Patrick B.","family":"Walter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2020.147066_b0005","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1089\/ars.2009.2668","article-title":"Lipid oxidation and peroxidation in CNS health and disease: from molecular mechanisms to therapeutic opportunities","volume":"12","author":"Adibhatla","year":"2010","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.brainres.2020.147066_b0010","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1002\/mds.25160","article-title":"Imaging striatal dopaminergic function in Phospholipase A2 Group VI\u2013related parkinsonism","volume":"27","author":"Agarwal","year":"2012","journal-title":"Movement Disorders"},{"key":"10.1016\/j.brainres.2020.147066_b0015","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/0166-2236(90)90107-L","article-title":"Functional architecture of basal ganglia circuits: neural substrates of parallel processing","volume":"13","author":"Alexander","year":"1990","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.brainres.2020.147066_b0020","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1146\/annurev.ne.09.030186.002041","article-title":"Parallel organization of functionally segregated circuits linking basal ganglia and cortex","volume":"9","author":"Alexander","year":"1986","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.brainres.2020.147066_b0025","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.jns.2007.03.020","article-title":"Enhanced visualization of axonopathy in EAE using thy1-YFP transgenic mice","volume":"260","author":"Bannerman","year":"2007","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.brainres.2020.147066_b0030","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1093\/brain\/awh550","article-title":"Motor neuron pathology in experimental autoimmune encephalomyelitis: studies in THY1-YFP transgenic mice","volume":"128","author":"Bannerman","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.brainres.2020.147066_b0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0153789","article-title":"Progressive axonal degeneration of nigrostriatal dopaminergic neurons in calcium-independent phospholipase A2\u03b2 knockout mice","volume":"11","author":"Beck","year":"2016","journal-title":"PLoS ONE"},{"key":"10.1016\/j.brainres.2020.147066_b0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0141629","article-title":"Deficiency of calcium-independent phospholipase A2 beta induces brain iron accumulation through upregulation of divalent metal transporter 1","volume":"10","author":"Beck","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.brainres.2020.147066_b0045","doi-asserted-by":"crossref","first-page":"11411","DOI":"10.1523\/JNEUROSCI.0345-11.2011","article-title":"Neuroaxonal dystrophy in calcium-independent phospholipase A2\u03b2 deficiency results from insufficient remodeling and degeneration of mitochondrial and presynaptic membranes","volume":"31","author":"Beck","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2020.147066_b0050","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/neu.480240105","article-title":"The distribution of tyrosine hydroxylase immunoreactivity in the brains of male and female zebra finches","volume":"24","author":"Bottjer","year":"1993","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.brainres.2020.147066_b0055","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.expneurol.2012.01.011","article-title":"Axon degeneration in Parkinson\u2019s disease","volume":"246","author":"Burke","year":"2013","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2020.147066_b0060","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/GIM.0b013e3181cd68ed","article-title":"Beta-thalassemia","volume":"12","author":"Cao","year":"2010","journal-title":"Genet. Med."},{"key":"10.1016\/j.brainres.2020.147066_b0065","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1113\/jphysiol.2007.149815","article-title":"Activity-dependent regulation of tyrosine hydroxylase expression in the enteric nervous system","volume":"586","author":"Chevalier","year":"2008","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/j.brainres.2020.147066_b0070","doi-asserted-by":"crossref","first-page":"7638","DOI":"10.1523\/JNEUROSCI.18-19-07638.1998","article-title":"Tyrosine hydroxylase expression in primary cultures of olfactory bulb: role of L-type calcium channels","volume":"18","author":"Cigola","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2020.147066_b0075","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/j.1471-4159.2012.07782.x","article-title":"The human testis-determining factor SRY localizes in midbrain dopamine neurons and regulates multiple components of catecholamine synthesis and metabolism","volume":"122","author":"Czech","year":"2012","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainres.2020.147066_b0080","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/S0896-6273(03)00568-3","article-title":"Parkinson\u2019s disease: mechanisms and models","volume":"39","author":"Dauer","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2020.147066_b0085","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0012897","article-title":"Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonism","volume":"5","author":"Engel","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.brainres.2020.147066_b0090","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/ncb748","article-title":"\u03b1-Synuclein is phosphorylated in synucleinopathy lesions","volume":"4","author":"Fujiwara","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.brainres.2020.147066_b0095","doi-asserted-by":"crossref","first-page":"4321","DOI":"10.1182\/blood-2011-03-283614","article-title":"\u03b2-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism","volume":"118","author":"Ginzburg","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.brainres.2020.147066_b0100","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1136\/jmg.2008.061929","article-title":"Clinical and genetic delineation of neurodegeneration with brain iron accumulation","volume":"46","author":"Gregory","year":"2009","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.brainres.2020.147066_b0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.14802\/jmd.14034","article-title":"Neurodegeneration with brain iron accumulation: diagnosis and management","volume":"8","author":"Hogarth","year":"2015","journal-title":"J. Mov. Disord."},{"key":"10.1016\/j.brainres.2020.147066_b0110","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0006-8993(93)91005-D","article-title":"Tyrosine hydroxylase protein and messenger RNA in the dopaminergic nigral neurons of patients with Parkinson\u2019s disease","volume":"606","author":"Kastner","year":"1993","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2020.147066_b0115","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1093\/brain\/awv132","article-title":"Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction","volume":"138","author":"Kinghorn","year":"2015","journal-title":"Brain"},{"key":"10.1016\/j.brainres.2020.147066_b0120","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/j.freeradbiomed.2013.09.001","article-title":"The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insights into the potential of various iron therapies to induce oxidative and nitrosative stress","volume":"65","author":"Koskenkorva-Frank","year":"2013","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.brainres.2020.147066_b0125","doi-asserted-by":"crossref","first-page":"99","DOI":"10.3389\/fphar.2014.00099","article-title":"Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms","volume":"5","author":"Levi","year":"2014","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.brainres.2020.147066_b0130","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.cmet.2018.05.019","article-title":"Phospholipase PLA2G6, a Parkinsonism-associated gene, affects Vps26 and Vps35, retromer function, and ceramide levels, similar to \u03b1-synuclein gain","volume":"28","author":"Lin","year":"2018","journal-title":"Cell Metab."},{"key":"10.1016\/j.brainres.2020.147066_b0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0079-6603(01)67023-5","article-title":"The molecular biology of the group VIA Ca2+-independent phospholipase A2","volume":"67","author":"Ma","year":"2001","journal-title":"Prog. Nucl. Acid Res. Mol. Biol."},{"key":"10.1016\/j.brainres.2020.147066_b0140","doi-asserted-by":"crossref","first-page":"406","DOI":"10.2353\/ajpath.2008.070823","article-title":"Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations","volume":"172","author":"Malik","year":"2008","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.brainres.2020.147066_b0145","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1113\/EP086328","article-title":"Utility and reliability of non-invasive muscle function tests in high-fat-fed mice","volume":"102","author":"Martinez-Huenchullan","year":"2017","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.brainres.2020.147066_b0150","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.nbd.2015.12.018","article-title":"Dynamic structural flexibility of \u03b1-synuclein","volume":"88","author":"Mor","year":"2016","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.brainres.2020.147066_b0155","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1038\/ng1826","article-title":"PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron","volume":"38","author":"Morgan","year":"2006","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2020.147066_b0160","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1159\/000112283","article-title":"Thy-1 in developing nervous tissue","volume":"7","author":"Morris","year":"1985","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.brainres.2020.147066_b0165","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0306-4522(02)00578-X","article-title":"Dose- and sex-dependent effects of the neurotoxin 6-hydroxydopamine on the nigrostriatal dopaminergic pathway of adult rats: differential actions of estrogen in males and females","volume":"116","author":"Murray","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2020.147066_b0170","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/cne.21148","article-title":"Sex and species differences in tyrosine hydroxylase-synthesizing cells of the rodent olfactory extended amygdala","volume":"500","author":"Northcutt","year":"2007","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.brainres.2020.147066_b0175","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/ana.21415","article-title":"Characterization of PLA2G6 as a locus for dystonia-parkinsonism","volume":"65","author":"Paisan-Ruiz","year":"2009","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2020.147066_b0180","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/nn.3283","article-title":"Neural signals of extinction in the inhibitory microcircuit of the ventral midbrain","volume":"16","author":"Pan","year":"2013","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainres.2020.147066_b0185","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1093\/bioinformatics\/btp184","article-title":"Globally optimal stitching of tiled 3D microscopic image acquisitions","volume":"25","author":"Preibisch","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.brainres.2020.147066_b0190","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1351\/pac200779122325","article-title":"Fenton chemistry in biology and medicine","volume":"79","author":"Prousek","year":"2007","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.brainres.2020.147066_b0195","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/1471-2202-13-95","article-title":"Testosterone regulation of sex steroid-related mRNAs and dopamine-related mRNAs in adolescent male rat substantia nigra","volume":"13","author":"Purves-Tyson","year":"2012","journal-title":"BMC Neuroscience"},{"key":"10.1016\/j.brainres.2020.147066_b0200","doi-asserted-by":"crossref","DOI":"10.3791\/3516","article-title":"Spectral confocal imaging of fluorescently tagged nicotinic receptors in knock-in mice with chronic nicotine administration","author":"Renda","year":"2012","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.brainres.2020.147066_b0205","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/nrn3453","article-title":"Iron metabolism in the CNS: implications for neurodegenerative diseases","volume":"14","author":"Rouault","year":"2013","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.brainres.2020.147066_b0210","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1038\/nchembio807","article-title":"The role of iron regulatory proteins in mammalian iron homeostasis and disease","volume":"2","author":"Rouault","year":"2006","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.brainres.2020.147066_b0215","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/ng1196-348","article-title":"Mice lacking both subunits of lysosomal beta-hexosaminidase display gangliosidosis and mucopolysaccharidosis","volume":"14","author":"Sango","year":"1996","journal-title":"Nat. Genet."},{"key":"10.1016\/j.brainres.2020.147066_b0220","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1002\/mds.22314","article-title":"Complicated recessive dystonia parkinsonism syndromes","volume":"24","author":"Schneider","year":"2009","journal-title":"Mov. Disord."},{"key":"10.1016\/j.brainres.2020.147066_b0225","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/mds.23971","article-title":"Syndromes of neurodegeneration with brain iron accumulation (NBIA): an update on clinical presentations, histological and genetic underpinnings, and treatment considerations","volume":"27","author":"Schneider","year":"2012","journal-title":"Mov. Disord."},{"key":"10.1016\/j.brainres.2020.147066_b0230","doi-asserted-by":"crossref","first-page":"S34","DOI":"10.1016\/S1471-1931(00)00025-2","article-title":"Dopamine receptors: from structure to behavior","volume":"23","author":"Sealfon","year":"2000","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.brainres.2020.147066_b0235","doi-asserted-by":"crossref","DOI":"10.3791\/52434-v","article-title":"Use of the open field maze to measure locomotor and anxiety-like behavior in mice","author":"Seibenhener","year":"2015","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.brainres.2020.147066_b0240","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1523\/JNEUROSCI.4354-07.2008","article-title":"Neuroaxonal dystrophy caused by group VIA phospholipase A2 deficiency in mice: a model of human neurodegenerative disease","volume":"28","author":"Shinzawa","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainres.2020.147066_b0245","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.neuint.2017.03.004","article-title":"Neurons and astrocytes in an infantile neuroaxonal dystrophy (INAD) mouse model show characteristic alterations in glutamate-induced Ca2+ signaling","volume":"108","author":"Strokin","year":"2017","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainres.2020.147066_b0250","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.neuint.2016.07.002","article-title":"Mitochondria from a mouse model of the human infantile neuroaxonal dystrophy (INAD) with genetic defects in VIA iPLA2 have disturbed Ca(2+) regulation with reduction in Ca(2+) capacity","volume":"99","author":"Strokin","year":"2016","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainres.2020.147066_b0255","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1093\/hmg\/dds108","article-title":"Severe disturbance in the Ca2+ signaling in astrocytes from mouse models of human infantile neuroaxonal dystrophy with mutated Pla2g6","volume":"21","author":"Strokin","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.brainres.2020.147066_b0260","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s12017-009-8092-z","article-title":"Phospholipases A2 and inflammatory responses in the central nervous system","volume":"12","author":"Sun","year":"2010","journal-title":"Neuromolecular Med."},{"key":"10.1016\/j.brainres.2020.147066_b0265","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3233\/JPD-150769","article-title":"Retrograde axonal degeneration in Parkinson disease","volume":"6","author":"Tagliaferro","year":"2016","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.brainres.2020.147066_b0270","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0079-6123(06)60011-3","article-title":"GABAergic control of substantia nigra dopaminergic neurons","volume":"160","author":"Tepper","year":"2007","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.brainres.2020.147066_b0275","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.2353\/ajpath.2009.090343","article-title":"Establishment of an improved mouse model for infantile neuroaxonal dystrophy that shows early disease onset and bears a point mutation in Pla2g6","volume":"175","author":"Wada","year":"2009","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.brainres.2020.147066_b0280","doi-asserted-by":"crossref","first-page":"30879","DOI":"10.1074\/jbc.271.48.30879","article-title":"Expression, purification, and kinetic characterization of a recombinant 80-kDa intracellular calcium-independent phospholipase A2","volume":"271","author":"Wolf","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainres.2020.147066_b0285","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1212\/WNL.0b013e3181f73649","article-title":"Phenotypic spectrum of patients with PLA2G6 mutation and PARK14-linked parkinsonism","volume":"75","author":"Yoshino","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.brainres.2020.147066_b0290","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0026991","article-title":"Genetic ablation of PLA2G6 in mice leads to cerebellar atrophy characterized by Purkinje cell loss and glial cell activation","volume":"6","author":"Zhao","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.brainres.2020.147066_b0295","doi-asserted-by":"crossref","first-page":"10332","DOI":"10.1038\/ncomms10332","article-title":"Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson\u2019s disease","volume":"7","author":"Zhou","year":"2016","journal-title":"Nat. Commun."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899320304248?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899320304248?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T18:14:16Z","timestamp":1757787256000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899320304248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":59,"alternative-id":["S0006899320304248"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2020.147066","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Loss of tyrosine hydroxylase, motor deficits and elevated iron in a mouse model of phospholipase A2G6-associated neurodegeneration (PLAN)","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2020.147066","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"147066"}}