{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T07:05:42Z","timestamp":1768547142293,"version":"3.49.0"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HD069620"],"award-info":[{"award-number":["HD069620"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS084967"],"award-info":[{"award-number":["NS084967"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS094950"],"award-info":[{"award-number":["NS094950"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS099674"],"award-info":[{"award-number":["NS099674"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS099683"],"award-info":[{"award-number":["NS099683"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS110609"],"award-info":[{"award-number":["NS110609"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS113810"],"award-info":[{"award-number":["NS113810"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011582","name":"College of Business, University of Central Arkansas","doi-asserted-by":"publisher","award":["NS07433"],"award-info":[{"award-number":["NS07433"]}],"id":[{"id":"10.13039\/100011582","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011582","name":"College of Business, University of Central Arkansas","doi-asserted-by":"publisher","award":["NS086749"],"award-info":[{"award-number":["NS086749"]}],"id":[{"id":"10.13039\/100011582","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.brainres.2021.147544","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T17:11:49Z","timestamp":1622826709000},"page":"147544","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Chronic unpredictable stress during adolescence protects against adult traumatic brain injury-induced affective and cognitive deficits"],"prefix":"10.1016","volume":"1767","author":[{"given":"Patricia B.","family":"de la Tremblaye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3254-2002","authenticated-orcid":false,"given":"JoDy L.","family":"Wellcome","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3584-6722","authenticated-orcid":false,"given":"Kaitlyn","family":"Wiley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn A.","family":"Lomahan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleni H.","family":"Moschonas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey P.","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corina O.","family":"Bondi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony E.","family":"Kline","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2021.147544_b0005","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1089\/neu.2015.3992","article-title":"The evolution of post-traumatic stress disorder following moderate-to-severe traumatic brain injury","volume":"33","author":"Alway","year":"2016","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2021.147544_b0010","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.tins.2008.01.004","article-title":"Stress, sensitive periods and maturational events in adolescent depression","volume":"31","author":"Andersen","year":"2008","journal-title":"Trends Neurosci.."},{"key":"10.1016\/j.brainres.2021.147544_b0015","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/acn3.163","article-title":"Cannabinoid agonist rescues learning and memory after a traumatic brain injury","volume":"2","author":"Arain","year":"2015","journal-title":"Ann. Clin. Transl. Neurol."},{"key":"10.1016\/j.brainres.2021.147544_b0020","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1007\/s12035-016-9731-7","article-title":"Arachidonyl-2-chloroethylamide alleviates cerebral ischemia injury through glycogen synthase kinase-3\u03b2-mediated mitochondrial biogenesis and functional improvement","volume":"54","author":"Bai","year":"2017","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.brainres.2021.147544_b0025","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/hipo.22608","article-title":"Pro-cognitive action of CART is mediated via ERK in the hippocampus","volume":"26","author":"Bharne","year":"2016","journal-title":"Hippocampus"},{"key":"10.1016\/j.brainres.2021.147544_b0030","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.brainres.2019.03.007","article-title":"Environmental enrichment and amantadine confer individual but nonadditive enhancements in motor and spatial learning after controlled cortical impact injury","volume":"1714","author":"Bleimeister","year":"2019","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2021.147544_b0035","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1089\/neu.2013.3295","article-title":"Old dog, new tricks: the attentional set-shifting test as a novel cognitive behavioral task after controlled cortical impact injury","volume":"31","author":"Bondi","year":"2014","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2021.147544_b0040","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1097\/NMD.0b013e318199fe7f","article-title":"Early stage assessment and course of acute stress disorder after mild traumatic brain injury","volume":"197","author":"Broomhall","year":"2009","journal-title":"J. Nerv. Ment. Dis."},{"key":"10.1016\/j.brainres.2021.147544_b0045","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/jnc.13288","article-title":"Cannabinoid receptor type 1 agonist ACEA improves motor recovery and protects neurons in ischemic stroke in mice","volume":"135","author":"Caltana","year":"2015","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainres.2021.147544_b0050","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.bbr.2014.09.003","article-title":"Chronic unpredictable stress during adolescence causes long-term anxiety","volume":"278","author":"Chaby","year":"2015","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2021.147544_b0055","doi-asserted-by":"crossref","first-page":"327","DOI":"10.3389\/fnbeh.2015.00327","article-title":"Chronic stress during adolescence impairs and improves learning and memory in adulthood","volume":"9","author":"Chaby","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.brainres.2021.147544_b0060","doi-asserted-by":"crossref","first-page":"328","DOI":"10.3389\/fnhum.2013.00328","article-title":"Long-term changes in cognitive bias and coping response as a result of chronic unpredictable stress during adolescence","volume":"7","author":"Chaby","year":"2013","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.brainres.2021.147544_b0065","doi-asserted-by":"crossref","DOI":"10.1002\/syn.22034","article-title":"Dendrites of the dorsal and ventral hippocampal CA1 pyramidal neurons of singly housed female rats exhibit lamina-specific growths and retractions during adolescence that are responsive to pair housing","volume":"72","author":"Chen","year":"2018","journal-title":"Synapse"},{"key":"10.1016\/j.brainres.2021.147544_b0070","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.neubiorev.2017.05.022","article-title":"Elucidating opportunities and pitfalls in the treatment of experimental traumatic brain injury to optimize and facilitate clinical translation","volume":"85","author":"de la Tremblaye","year":"2018","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.brainres.2021.147544_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2020.113318","article-title":"Early life stress increases vulnerability to the sequelae of pediatric mild traumatic brain injury","volume":"329","author":"Diaz-Ch\u00e1vez","year":"2020","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2021.147544_b0080","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3109\/02699052.2015.1131848","article-title":"Prevalence of traumatic brain injury and epilepsy among prisoners in France: Results of the Fleury TBI study","volume":"30","author":"Durand","year":"2016","journal-title":"Brain Inj."},{"key":"10.1016\/j.brainres.2021.147544_b0085","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.lfs.2015.10.025","article-title":"Men and mice: relating their ages","volume":"152","author":"Dutta","year":"2016","journal-title":"Life Sci."},{"key":"10.1016\/j.brainres.2021.147544_b0090","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.bbi.2019.06.027","article-title":"Chronic psychological stress during adolescence induces sex-dependent adulthood inflammation, increased adiposity, and abnormal behaviors that are ameliorated by selective inhibition of soluble tumor necrosis factor with XPro1595","volume":"81","author":"Eidson","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.brainres.2021.147544_b0095","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neuroscience.2017.04.019","article-title":"Construct and face validity of a new model for the three-hit theory of depression using PACAP mutant mice on CD1 background","volume":"354","author":"Farkas","year":"2017","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainres.2021.147544_b0100","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1089\/neu.2015.3958","article-title":"Repetitive mild traumatic brain injury in the developing brain: effects on long-term functional outcome and neuropathology","volume":"33","author":"Fidan","year":"2016","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2021.147544_b0105","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.expneurol.2017.07.004","article-title":"Comparable impediment of cognitive function in female and male rats subsequent to daily administration of haloperidol after traumatic brain injury","volume":"296","author":"Free","year":"2017","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2021.147544_b0110","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/978-3-540-88955-7_12","article-title":"Integration of endocannabinoid signaling into the neural network regulating stress-induced activation of the hypothalamic-pituitary-adrenal axis","volume":"1","author":"Gorzalka","year":"2009","journal-title":"Curr. Top. Behav. Neurosci."},{"key":"10.1016\/j.brainres.2021.147544_b0115","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.physbeh.2005.06.027","article-title":"The effects of chronic unpredictable stress on male rats in the water maze","volume":"86","author":"Gouirand","year":"2005","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.brainres.2021.147544_b0120","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0053126","article-title":"Differential response of hippocampal subregions to stress and learning","volume":"7","author":"Hawley","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.brainres.2021.147544_b0125","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1089\/neu.2014.3619","article-title":"Associations between a history of traumatic brain injuries and current cigarette smoking, substance use, and elevated psychological distress in a population sample of canadian adults","volume":"32","author":"Ilie","year":"2015","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2021.147544_b0130","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.bbr.2014.08.056","article-title":"Pre and post-injury environmental enrichment effects functional recovery following medial frontal cortical contusion injury in rats","volume":"275","author":"Jacqmain","year":"2014","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2021.147544_b0135","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.biopsych.2015.03.033","article-title":"Anxiety, stress, and fear response in mice with reduced endocannabinoid levels","volume":"79","author":"Jenniches","year":"2016","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainres.2021.147544_b0140","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1038\/nn.3195","article-title":"Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury","volume":"15","author":"Ji","year":"2012","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainres.2021.147544_b0145","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1097\/01.CCM.0000256722.88854.C0","article-title":"Differential effects of single versus multiple administrations of haloperidol and risperidone on functional outcome after experimental brain trauma","volume":"35","author":"Kline","year":"2007","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.brainres.2021.147544_b0150","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1089\/neu.2010.1535","article-title":"Evaluation of a combined therapeutic regimen of 8-OH-DPAT and environmental enrichment after experimental traumatic brain injury","volume":"27","author":"Kline","year":"2010","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2021.147544_b0155","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1089\/neu.2012.2385","article-title":"Evaluation of a combined treatment paradigm consisting of environmental enrichment and the 5-HT1A receptor agonist buspirone after experimental traumatic brain injury","volume":"29","author":"Kline","year":"2012","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2021.147544_b0160","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0304-3940(00)00797-7","article-title":"Chronic methylphenidate treatment enhances water maze performance following traumatic brain injury in rats","volume":"280","author":"Kline","year":"2000","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainres.2021.147544_b0165","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.pnpbp.2015.10.010","article-title":"Endocannabinoid CB1 receptor activation upon global ischemia adversely impact recovery of reward and stress signaling molecules, neuronal survival and behavioral impulsivity","volume":"66","author":"Knowles","year":"2016","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.brainres.2021.147544_b0170","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.bbalip.2018.02.001","article-title":"\u03949-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult","volume":"1863","author":"Leishman","year":"2018","journal-title":"Biochim. Biophys. Acta, Mol. Cell. Biol. Lipids"},{"key":"10.1016\/j.brainres.2021.147544_b0175","doi-asserted-by":"crossref","first-page":"9763","DOI":"10.3390\/ijms21249763","article-title":"Low Basal CB2R in Dopamine neurons and microglia influences cannabinoid tetrad effects","volume":"21","author":"Liu","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.brainres.2021.147544_b0180","doi-asserted-by":"crossref","first-page":"12440","DOI":"10.1038\/srep12440","article-title":"Mitochondrial CB1 receptor is involved in ACEA-induced protective effects on neurons and mitochondrial functions","volume":"5","author":"Ma","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.brainres.2021.147544_b0185","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.neuropharm.2018.03.024","article-title":"Inhibition of mitochondrial permeability transition pore opening contributes to cannabinoid type 1 receptor agonist ACEA-induced neuroprotection","volume":"135","author":"Ma","year":"2018","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.brainres.2021.147544_b0190","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1089\/neu.2018.6063","article-title":"Role of CB2 receptor in the recovery of mice after traumatic brain injury","volume":"36","author":"Magid","year":"2019","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2021.147544_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2020.113522","article-title":"Preclinical neurorehabilitation with environmental enrichment confers cognitive and histological benefits in a model of pediatric asphyxial cardiac arrest","volume":"335","author":"Manole","year":"2021","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2021.147544_b0200","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.bbr.2012.09.053","article-title":"Upregulation of CB1 receptor binding in the ventromedial prefrontal cortex promotes proactive stress-coping strategies following chronic stress exposure","volume":"237","author":"McLaughlin","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2021.147544_b0205","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s12035-007-8008-6","article-title":"Endocannabinoids and traumatic brain injury","volume":"36","author":"Mechoulam","year":"2007","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.brainres.2021.147544_b0210","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/npp.2015.166","article-title":"Neurobiological interactions between stress and the endocannabinoid system","volume":"41","author":"Morena","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainres.2021.147544_b0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.147175","article-title":"Disruption of basal forebrain cholinergic neurons after traumatic brain injury does not compromise environmental enrichment-mediated cognitive benefits","volume":"1751","author":"Moschonas","year":"2021","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2021.147544_b0220","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1101\/lm.41302","article-title":"Hippocampal damage and exploratory preferences in rats: memory for objects, places, and contexts","volume":"9","author":"Mumby","year":"2002","journal-title":"Learn Mem."},{"key":"10.1016\/j.brainres.2021.147544_b0225","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.expneurol.2019.01.019","article-title":"Chronic treatment with galantamine rescues reversal learning in an attentional set-shifting test after experimental brain trauma","volume":"315","author":"Njoku","year":"2019","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2021.147544_b0230","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1089\/neu.2012.2358","article-title":"Traumatic brain injury-induced cognitive and histological deficits are attenuated by delayed and chronic treatment with the 5-HT1A receptor agonist buspirone","volume":"29","author":"Olsen","year":"2012","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2021.147544_b0235","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.3390\/cells9061507","article-title":"Role of 2-Arachidonoyl-Glycerol and CB1 receptors in orexin-A-mediated prevention of oxygen-glucose deprivation-induced neuronal injury","volume":"9","author":"Palomba","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.brainres.2021.147544_b0240","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/nrn2513","article-title":"Why do many psychiatric disorders emerge during adolescence?","volume":"9","author":"Paus","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.brainres.2021.147544_b0250","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1089\/neu.2014.3711","article-title":"Divergent long-term consequences of chronic treatment with haloperidol, risperidone, and bromocriptine on traumatic brain injury-induced cognitive deficits","volume":"32","author":"Phelps","year":"2015","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainres.2021.147544_b0255","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/ajad.12338","article-title":"Psychosis following traumatic brain injury and cannabis use in late adolescence","volume":"25","author":"Rabner","year":"2016","journal-title":"Am. J. Addict."},{"key":"10.1016\/j.brainres.2021.147544_b0260","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.expneurol.2016.09.015","article-title":"Abbreviated environmental enrichment confers neurobehavioral, cognitive, and histological benefits in brain-injured female rats","volume":"286","author":"Radabaugh","year":"2016","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2021.147544_b0265","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1177\/0269881113499207","article-title":"Cannabinoid modulation of chronic mild stress-induced selective enhancement of trace fear conditioning in adolescent rats","volume":"27","author":"Reich","year":"2013","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.brainres.2021.147544_b0270","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1159\/000446773","article-title":"Aging with traumatic brain injury: effects of age at injury on behavioral outcome following diffuse brain injury in rats","volume":"38","author":"Rowe","year":"2016","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.brainres.2021.147544_b0275","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1177\/0269881111408958","article-title":"The endocannabinoid system in anxiety, fear memory and habituation","volume":"26","author":"Ruehle","year":"2012","journal-title":"J. Psychopharmacol."},{"issue":"10","key":"10.1016\/j.brainres.2021.147544_b0280","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12641","article-title":"Factors promoting vulnerability to dysregulated stress reactivity and stress-related disease","volume":"30","author":"Russell","year":"2018","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.brainres.2021.147544_b0285","doi-asserted-by":"crossref","first-page":"786","DOI":"10.3389\/fphar.2018.00786","article-title":"Long-term stress and concomitant marijuana smoke exposure affect physiology, behavior and adult hippocampal neurogenesis","volume":"9","author":"Ruszn\u00e1k","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.brainres.2021.147544_b0290","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.psyneuen.2019.06.018","article-title":"Anandamide modulation of circadian- and stress-dependent effects on rat short-term memory","volume":"108","author":"Santori","year":"2019","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.brainres.2021.147544_b0295","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3389\/fphar.2017.00069","article-title":"Endocannabinoids: a promising impact for traumatic brain injury","volume":"8","author":"Schurman","year":"2017","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.brainres.2021.147544_b0300","first-page":"624","article-title":"The laboratory rat: relating its age with human's","volume":"4","author":"Sengupta","year":"2013","journal-title":"Int. J. Prev. Med."},{"key":"10.1016\/j.brainres.2021.147544_b0305","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1111\/j.1476-5381.2011.01343.x","article-title":"Endocannabinoids and traumatic brain injury","volume":"163","author":"Shohami","year":"2011","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.brainres.2021.147544_b0310","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1007\/s12640-017-9839-1","article-title":"Cannabinoid receptor type 1 agonist ACEA protects neurons from death and attenuates endoplasmic reticulum stress-related apoptotic pathway signaling","volume":"33","author":"Vrechi","year":"2018","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.brainres.2021.147544_b0315","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1176\/appi.ajp.2013.13070920","article-title":"Structural brain development and depression onset during adolescence: a prospective longitudinal study","volume":"171","author":"Whittle","year":"2014","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainres.2021.147544_b0320","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/s41420-020-00338-3","article-title":"Cannabinoid CB1 receptor agonist ACEA alleviates brain ischemia\/reperfusion injury via CB1-Drp1 pathway","volume":"6","author":"Yang","year":"2020","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.brainres.2021.147544_b0325","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.bbr.2019.01.008","article-title":"PI3K\/Akt\/NF-\u03baB signaling pathway regulates behaviors in adolescent female rats following with neonatal maternal deprivation and chronic mild stress","volume":"362","author":"Ye","year":"2019","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2021.147544_b0330","doi-asserted-by":"crossref","first-page":"9382797","DOI":"10.1155\/2017\/9382797","article-title":"Neuroplastic correlates in the mPFC underlying the impairment of stress-coping ability and cognitive flexibility in adult rats exposed to chronic mild stress during adolescence","volume":"2017","author":"Zhang","year":"2017","journal-title":"Neural Plast."},{"key":"10.1016\/j.brainres.2021.147544_b0335","doi-asserted-by":"crossref","first-page":"4454","DOI":"10.1093\/cercor\/bhy258","article-title":"Neural stem cell lineage-specific cannabinoid type-1 receptor regulates neurogenesis and plasticity in the adult mouse hippocampus","volume":"28","author":"Zimmermann","year":"2018","journal-title":"Cereb. Cortex"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899321004017?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899321004017?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T17:05:09Z","timestamp":1762103109000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899321004017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":66,"alternative-id":["S0006899321004017"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2021.147544","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic unpredictable stress during adolescence protects against adult traumatic brain injury-induced affective and cognitive deficits","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2021.147544","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"147544"}}