{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T17:50:47Z","timestamp":1793469047299,"version":"4.5.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100007605","name":"Aarhus Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007605","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","award":["2013-14933"],"award-info":[{"award-number":["2013-14933"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004836","name":"Independent Research Fund Denmark","doi-asserted-by":"publisher","award":["8020-00310B"],"award-info":[{"award-number":["8020-00310B"]}],"id":[{"id":"10.13039\/501100004836","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011958","name":"Danmarks Frie Forskningsfond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011958","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.brainres.2021.147648","type":"journal-article","created":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T10:26:45Z","timestamp":1630751205000},"page":"147648","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Behavioral and histopathological consequences of transient ischemic stroke in the Flinders Sensitive Line rat, a genetic animal model of depression"],"prefix":"10.1016","volume":"1771","author":[{"given":"Denise F.","family":"Happ","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregers","family":"Wegener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Andrew","family":"Tasker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.brainres.2021.147648_b0005","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.psyneuen.2010.09.004","article-title":"A high-fat diet exacerbates depressive-like behavior in the Flinders Sensitive Line (FSL) rat, a genetic model of depression","volume":"36","author":"Abildgaard","year":"2011","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.brainres.2021.147648_b0010","first-page":"50014","article-title":"Endothelin-1 induced middle cerebral artery occlusion model for ischemic stroke with laser Doppler flowmetry guidance in rat","volume":"72","author":"Ansari","year":"2013","journal-title":"J. Vis. Exp"},{"key":"10.1016\/j.brainres.2021.147648_b0015","doi-asserted-by":"crossref","unstructured":"Arbelaez, J.J., Ariyo, A.A., Crum, R.M., Fried, L.P., Ford, D.E., 2007. Depressive Symptoms, Inflammation, and Ischemic Stroke in Older Adults: A Prospective Analysis in the Cardiovascular Health Study. J. Am. Geriatr. Soc. 55, 1825\u20131830. 10.1111\/j.1532-5415.2007.01393.x.","DOI":"10.1111\/j.1532-5415.2007.01393.x"},{"issue":"6","key":"10.1016\/j.brainres.2021.147648_b0020","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/bph.13714","article-title":"Rapid antidepressant effect of ketamine correlates with astroglial plasticity in the hippocampus","volume":"174","author":"Ardalan","year":"2017","journal-title":"Brit. J. Pharmacol."},{"issue":"11","key":"10.1016\/j.brainres.2021.147648_b0025","doi-asserted-by":"crossref","first-page":"3258","DOI":"10.1161\/STROKEAHA.110.607705","article-title":"Stress worsens endothelial function and ischemic stroke via glucocorticoids","volume":"42","author":"Balkaya","year":"2011","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0030","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1161\/01.RES.62.1.56","article-title":"Mechanics of cerebral arterioles in hypertensive rats","volume":"62","author":"Baumbach","year":"1988","journal-title":"Circ. Res."},{"key":"10.1016\/j.brainres.2021.147648_b0035","doi-asserted-by":"crossref","first-page":"146797","DOI":"10.1016\/j.brainres.2020.146797","article-title":"Flinders sensitive line rats are resistant to infarction following transient occlusion of the middle cerebral artery","volume":"1737","author":"Bay","year":"2020","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0040","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.brainres.2006.07.123","article-title":"Use of TTC staining for the evaluation of tissue injury in the early phases of reperfusion after focal cerebral ischemia in rats","volume":"1116","author":"Benedek","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2021.147648_b0045","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.physbeh.2013.05.012","article-title":"Factors influencing behavior in the forced swim test","volume":"118","author":"Bogdanova","year":"2013","journal-title":"Physiol. Behav."},{"issue":"2","key":"10.1016\/j.brainres.2021.147648_b0050","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.bbr.2005.09.013","article-title":"Anxiety-like behaviors in pre-pubertal rats of the Flinders Sensitive Line (FSL) and Wistar-Kyoto (WKY) animal models of depression","volume":"167","author":"Braw","year":"2006","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0055","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1161\/01.HYP.5.1.17","article-title":"Biochemical and mechanical properties of resistance arteries from normotensive and hypertensive rats","volume":"5","author":"Brayden","year":"1983","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0060","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.pbb.2007.11.004","article-title":"Differential effect of environment enrichment and social isolation on depressive-like behavior, spontaneous activity and serotonin and norepinephrine concentration in prefrontal cortex and ventral striatum","volume":"89","author":"Brenes","year":"2008","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"3","key":"10.1016\/j.brainres.2021.147648_b0065","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1038\/npp.2014.257","article-title":"Diurnal fluctuations in HPA and neuropeptide Y-ergic systems underlie differences in vulnerability to traumatic stress responses at different zeitgeber times","volume":"40","author":"Cohen","year":"2015","journal-title":"Neuropsychopharmacol."},{"issue":"jul26 1","key":"10.1016\/j.brainres.2021.147648_b0070","doi-asserted-by":"crossref","first-page":"3666","DOI":"10.1136\/bmj.c3666","article-title":"The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: Systematic review and meta-analysis","volume":"341","author":"Debette","year":"2010","journal-title":"BMJ"},{"issue":"20","key":"10.1016\/j.brainres.2021.147648_b0075","doi-asserted-by":"crossref","first-page":"11824","DOI":"10.1073\/pnas.201215298","article-title":"Social stress exacerbates stroke outcome by suppressing Bcl-2 expression","volume":"98","author":"DeVries","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0080","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1161\/STROKEAHA.111.630871","article-title":"Depression and risk of stroke: a meta-analysis of prospective studies","volume":"43","author":"Dong","year":"2012","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2021.147648_b0085","doi-asserted-by":"crossref","unstructured":"Endo, Y., Jinnai, K., Endo, M., Fujita, K., Kimura, F., 1990. Diurnal variation of cerebral blood flow in rat hippocampus. Stoke 21, 1464-9. https:\/\/doi: 10.1161\/01.str.21.10.1464.","DOI":"10.1161\/01.STR.21.10.1464"},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0090","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1136\/svn-2017-000119","article-title":"Prestroke selective serotonin reuptake inhibitor use and functional outcomes after ischaemic stroke","volume":"3","author":"Etherton","year":"2018","journal-title":"Stroke Vasc. Neurol."},{"issue":"10069","key":"10.1016\/j.brainres.2021.147648_b0095","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0140-6736(16)30962-X","article-title":"Stroke","volume":"389","author":"Hankey","year":"2017","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.brainres.2021.147648_b0100","doi-asserted-by":"crossref","first-page":"112234","DOI":"10.1016\/j.bbr.2019.112234","article-title":"Effect of ischemic lesions in medial prefrontal cortex and nucleus accumbens on affective behavior in rats","volume":"378","author":"Happ","year":"2020","journal-title":"Behav. Brain Res."},{"issue":"2","key":"10.1016\/j.brainres.2021.147648_b0105","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0022-0736(99)90095-X","article-title":"Diurnal variation of autonomic nervous activity in the rat: investigation by power spectral analysis of heart rate variability","volume":"32","author":"Hashimoto","year":"1999","journal-title":"J. Electrocardiol."},{"issue":"2","key":"10.1016\/j.brainres.2021.147648_b0110","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s12640-019-00138-3","article-title":"Endothelin-1-Induced Ischemic Damage and Functional Impairment Is Mediated Primarily by NR2B-Containing NMDA Receptors","volume":"37","author":"Hume","year":"2020","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.brainres.2021.147648_b0115","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCOUTCOMES.117.004500","article-title":"Psychological Distress and Risk of Myocardial Infarction and Stroke in the 45 and Up Study","volume":"11","author":"Jackson","year":"2018","journal-title":"Circ. Cardiovasc. Qual. Outcomes"},{"key":"10.1016\/j.brainres.2021.147648_b0120","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.brainres.2010.09.081","article-title":"The effect of stress on stroke recovery in a photothrombotic stroke animal model","volume":"1363","author":"Jin","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2021.147648_b0125","doi-asserted-by":"crossref","unstructured":"Joynt, K.E., Whellan, D.J., O\u2019Connor, C.M., 2003. Depression and cardiovascular disease: Mechanisms of interaction. Biol. Psychiatry. 10.1016\/S0006-3223(03)00568-7.","DOI":"10.1016\/S0006-3223(03)00568-7"},{"key":"10.1016\/j.brainres.2021.147648_b0130","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.brainres.2008.01.032","article-title":"Delayed recovery and exaggerated infarct size by post-lesion stress in a rat model of focal cerebral stroke","volume":"1201","author":"Kirkland","year":"2008","journal-title":"Brain Res."},{"issue":"4","key":"10.1016\/j.brainres.2021.147648_b0135","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1002\/jnr.21899","article-title":"Fluoxetine affords robust neuroprotection in the postischemic brain via its anti-inflammatory effect","volume":"87","author":"Lim","year":"2009","journal-title":"J. Neurosci. Res."},{"issue":"1-2","key":"10.1016\/j.brainres.2021.147648_b0140","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0006-8993(03)02892-0","article-title":"Effect of subacute and chronic immobilisation stress on the outcome of permanent focal cerebral ischaemia in rats","volume":"979","author":"Madrigal","year":"2003","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbr.2005.04.023","article-title":"Reward and anxiety in genetic animal models of childhood depression","volume":"164","author":"Malkesman","year":"2005","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2021.147648_b0150","doi-asserted-by":"crossref","DOI":"10.1161\/STROKEAHA.112.673947","article-title":"Selective serotonin reuptake inhibitors for stroke recovery: A systematic review and meta-analysis","author":"Mead","year":"2013","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0155","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.bbr.2010.04.035","article-title":"Synergistic effects of age and stress in a rodent model of stroke","volume":"214","author":"Merrett","year":"2010","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainres.2021.147648_b0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/3456943","article-title":"A Review of Risk Factors for Cognitive Impairment in Stroke Survivors","volume":"2016","author":"Mohd Zulkifly","year":"2016","journal-title":"ScientificWorldJournal."},{"issue":"7","key":"10.1016\/j.brainres.2021.147648_b0165","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1161\/STROKEAHA.114.005302","article-title":"Impact of Prestroke Selective Serotonin Reuptake Inhibitor Treatment on Stroke Severity and Mortality","volume":"45","author":"Mortensen","year":"2014","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2021.147648_b0170","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1600-0404.2010.01373.x","article-title":"Depression predicts unfavourable functional outcome and higher mortality in stroke patients: The Bergen Stroke Study","volume":"122","author":"Naess","year":"2010","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.brainres.2021.147648_b0175","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1159\/000478851","article-title":"Cognitive Deficits in Chronic Stroke Patients: Neuropsychological Assessment, Depression, and Self-Reports","volume":"7","author":"Nakling","year":"2017","journal-title":"Dement. Geriatr. Cogn. Dis. Extra"},{"issue":"4-5","key":"10.1016\/j.brainres.2021.147648_b0180","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.neubiorev.2005.03.015","article-title":"The Flinders Sensitive Line rat: A selectively bred putative animal model of depression","volume":"29","author":"Overstreet","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"2-3","key":"10.1016\/j.brainres.2021.147648_b0185","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.ejphar.2004.04.010","article-title":"Antidepressant effects of citalopram and CRF receptor antagonist CP-154,526 in a rat model of depression","volume":"492","author":"Overstreet","year":"2004","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0190","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/BF02245589","article-title":"Administration of antidepressants, diazepam and psychomotor stimulants further confirms the utility of Flinders Sensitive Line rats as an animal model of depression","volume":"121","author":"Overstreet","year":"1995","journal-title":"Psychopharmacology (Berl)."},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0195","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1124\/pr.111.005397","article-title":"The flinders sensitive line rat model of depression\u201325 years and still producing","volume":"65","author":"Overstreet","year":"2013","journal-title":"Pharmacol. Rev."},{"issue":"11","key":"10.1016\/j.brainres.2021.147648_b0200","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1001\/jama.2011.1282","article-title":"Depression and Risk of Stroke Morbidity and Mortality","volume":"306","author":"Pan","year":"2011","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.brainres.2021.147648_b0205","doi-asserted-by":"crossref","first-page":"e0171688","DOI":"10.1371\/journal.pone.0171688","article-title":"Evolution of ischemic damage and behavioural deficit over 6 months after MCAo in the rat: Selecting the optimal outcomes and statistical power for multi-centre preclinical trials","volume":"12","author":"Rewell","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.brainres.2021.147648_b0210","first-page":"131","article-title":"Endothelins and the cerebral circulation","volume":"7","author":"Salom","year":"1995","journal-title":"Cerebrovasc. Brain Metab. Rev."},{"key":"10.1016\/j.brainres.2021.147648_b0215","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1097\/FBP.0b013e3282ee2aa8","article-title":"The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior","volume":"18","author":"Schmidt","year":"2007","journal-title":"Behav. Pharmacol."},{"issue":"7","key":"10.1016\/j.brainres.2021.147648_b0220","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/j.amjcard.2005.05.064","article-title":"Role of depression and inflammation in incident coronary heart disease events","volume":"96","author":"Shimbo","year":"2005","journal-title":"Am. J. Cardiol."},{"issue":"2","key":"10.1016\/j.brainres.2021.147648_b0225","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.pnpbp.2012.02.008","article-title":"Effect of early life housing manipulation on baseline and drug-induced behavioural responses on neurochemistry in the male rat","volume":"37","author":"Simpson","year":"2012","journal-title":"Prog. Neuro-Psychopharmacology Biol. Psychiatry"},{"key":"10.1016\/j.brainres.2021.147648_b0230","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1042\/CS20090108","article-title":"Evaluation of the relationship between hyperinsulinaemia and myocardial ischaemia\/reperfusion injury in a rat model of depression","volume":"118","author":"Solskov","year":"2009","journal-title":"Clin. Sci. (Lond)"},{"key":"10.1016\/j.brainres.2021.147648_b0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/932757","article-title":"Rodent models of depression: neurotrophic and neuroinflammatory biomarkers","volume":"2014","author":"Stepanichev","year":"2014","journal-title":"Biomed Res. Int."},{"issue":"2","key":"10.1016\/j.brainres.2021.147648_b0240","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1136\/jnnp.57.2.202","article-title":"Cognitive impairment after stroke: frequency, patterns, and relationship to functional abilities","volume":"57","author":"Tatemichi","year":"1994","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.brainres.2021.147648_b0245","doi-asserted-by":"crossref","unstructured":"Uvn\u00e4s-Moberg, K., Eklund, M., Hillegaart, V., Ahlenius, S. Improved conditioned avoidance learning by oxytocin administration in high-emotional male Sprague-Dawley rats. Reg. Peptides 88, 27-32. 10.1016\/S0167-0115(99)00112-3.","DOI":"10.1016\/S0167-0115(99)00112-3"},{"key":"10.1016\/j.brainres.2021.147648_bib276","doi-asserted-by":"crossref","first-page":"e863","DOI":"10.1038\/tp.2016.124","article-title":"Persistent post-stroke depression in mice following unilateral medial prefrontal cortical stroke","volume":"6","author":"Vahid-Ansari","year":"2016","journal-title":"Transl. Psychiatry"},{"issue":"03","key":"10.1016\/j.brainres.2021.147648_b0250","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1017\/S1461145711000678","article-title":"Neuropeptide S alters anxiety, but not depression-like behaviour in Flinders Sensitive Line rats: a genetic animal model of depression.","volume":"15","author":"Wegener","year":"2012","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.brainres.2021.147648_b0255","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.brainres.2007.02.050","article-title":"Locomotor response to novelty as a predictor of reactivity to aversive stimuli in the rat","volume":"1149","author":"White","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2021.147648_b0265","unstructured":"World Health Organization, 2017. Depression and Other Common Mental Disorders: Global Health Estimates Licence: CC BY-NC-SA 3.0 IGO."},{"issue":"2","key":"10.1016\/j.brainres.2021.147648_b0260","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.expneurol.2006.04.012","article-title":"An analysis of four different methods of producing focal cerebral ischemia with endothelin-1 in the rat","volume":"201","author":"Windle","year":"2006","journal-title":"Exp. Neurol."},{"issue":"12","key":"10.1016\/j.brainres.2021.147648_b0270","doi-asserted-by":"crossref","first-page":"e01166","DOI":"10.1002\/brb3.1166","article-title":"Left-right asymmetry influenced the infarct volume and neurological dysfunction following focal middle cerebral artery occlusion in rats","volume":"8","author":"Zhai","year":"2018","journal-title":"Brain Behav."},{"issue":"1","key":"10.1016\/j.brainres.2021.147648_b0275","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.bbr.2009.06.030","article-title":"Predictable stress versus unpredictable stress: A comparison in a rodent model of stroke","volume":"205","author":"Zucchi","year":"2009","journal-title":"Behav. Brain Res."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899321005059?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899321005059?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T17:05:40Z","timestamp":1762103140000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899321005059"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":56,"alternative-id":["S0006899321005059"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2021.147648","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Behavioral and histopathological consequences of transient ischemic stroke in the Flinders Sensitive Line rat, a genetic animal model of depression","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2021.147648","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"147648"}}