{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T07:39:49Z","timestamp":1789717189700,"version":"4.0.1"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22076104"],"award-info":[{"award-number":["22076104"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.brainres.2022.148133","type":"journal-article","created":{"date-parts":[[2022,10,29]],"date-time":"2022-10-29T19:33:04Z","timestamp":1667071984000},"page":"148133","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["The induction of ferroptosis in posthemorrhagic hydrocephalus"],"prefix":"10.1016","volume":"1798","author":[{"given":"Zilin","family":"Meng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunbo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanglin","family":"Di","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2022.148133_b0005","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.ydbio.2013.07.003","article-title":"Disruption of the mouse Jhy gene causes abnormal ciliary microtubule patterning and juvenile hydrocephalus","volume":"382","author":"Appelbe","year":"2013","journal-title":"Dev. Biol."},{"key":"10.1016\/j.brainres.2022.148133_b0010","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/360438","article-title":"Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal","volume":"2014","author":"Ayala","year":"2014","journal-title":"Oxid. Med. Cell Longev."},{"key":"10.1016\/j.brainres.2022.148133_b0020","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1080\/15548627.2020.1810918","article-title":"Ferroptosis: machinery and regulation","volume":"17","author":"Chen","year":"2021","journal-title":"Autophagy."},{"key":"10.1016\/j.brainres.2022.148133_b0025","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.brainres.2022.148133_b0030","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.nbd.2016.05.011","article-title":"Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC","volume":"94","author":"Do Van","year":"2016","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.brainres.2022.148133_b0035","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/nchembio.2239","article-title":"ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition","volume":"13","author":"Doll","year":"2017","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.brainres.2022.148133_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.trsl.2016.08.004","article-title":"Intraventricular administration of urokinase as a novel therapeutic approach for communicating hydrocephalus","volume":"180","author":"Feng","year":"2017","journal-title":"Transl Res."},{"key":"10.1016\/j.brainres.2022.148133_b0045","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1038\/ncb3064","article-title":"Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice","volume":"16","author":"Friedmann Angeli","year":"2014","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.brainres.2022.148133_b0050","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/s12974-014-0200-9","article-title":"Extracellular hemoglobin - mediator of inflammation and cell death in the choroid plexus following preterm intraventricular hemorrhage","volume":"11","author":"Gram","year":"2014","journal-title":"J. Neuroinflammation."},{"key":"10.1016\/j.brainres.2022.148133_b0055","first-page":"1317","article-title":"A marker for primary choroid plexus neoplasms","volume":"136","author":"Herbert","year":"1990","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.brainres.2022.148133_b0060","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1023\/A:1021691918517","article-title":"Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits","volume":"29","author":"Holcomb","year":"1999","journal-title":"Behav. Genet."},{"key":"10.1016\/j.brainres.2022.148133_b0065","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1038\/nm.4361","article-title":"Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus","volume":"23","author":"Karimy","year":"2017","journal-title":"Nat. Med."},{"key":"10.1016\/j.brainres.2022.148133_b0070","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/s41582-020-0321-y","article-title":"Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets","volume":"16","author":"Karimy","year":"2020","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.brainres.2022.148133_b0075","unstructured":"Koleva, M., De Jesus, O., 2022. Hydrocephalus. In StatPearls. Vol., ed.^eds. \u00a9 2022, StatPearls Publishing LLC., Treasure Island FL."},{"key":"10.1016\/j.brainres.2022.148133_b0080","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/978-1-4939-8994-2_10","article-title":"The Y-Maze for Assessment of Spatial Working and Reference Memory in Mice","volume":"1916","author":"Kraeuter","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.brainres.2022.148133_b0085","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41419-020-2298-2","article-title":"Ferroptosis: past, present and future","volume":"11","author":"Li","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.brainres.2022.148133_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.108486","article-title":"Pharmacological inhibition of TLR4-NF-\u03baB signaling by TAK-242 attenuates hydrocephalus after intraventricular hemorrhage","volume":"103","author":"Lin","year":"2022","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.brainres.2022.148133_b0095","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1161\/01.STR.28.1.141","article-title":"Ventricular dilatation in experimental intraventricular hemorrhage in pigs. Characterization of cerebrospinal fluid dynamics and the effects of fibrinolytic treatment","volume":"28","author":"Mayfrank","year":"1997","journal-title":"Stroke"},{"key":"10.1016\/j.brainres.2022.148133_b0100","doi-asserted-by":"crossref","first-page":"63","DOI":"10.2176\/nmc.st.2020-0292","article-title":"Guidelines for Management of Idiopathic Normal Pressure Hydrocephalus (Third Edition): Endorsed by the Japanese Society of Normal Pressure Hydrocephalus","volume":"61","author":"Nakajima","year":"2021","journal-title":"Neurol. Med. Chir. (Tokyo)."},{"key":"10.1016\/j.brainres.2022.148133_b0105","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.spen.2009.01.002","article-title":"A contemporary definition and classification of hydrocephalus","volume":"16","author":"Rekate","year":"2009","journal-title":"Semin. Pediatr. Neurol."},{"key":"10.1016\/j.brainres.2022.148133_b0110","doi-asserted-by":"crossref","DOI":"10.3390\/cells10081911","article-title":"Cumulative Damage: Cell Death in Posthemorrhagic Hydrocephalus of Prematurity","volume":"10","author":"Sevensky","year":"2021","journal-title":"Cells."},{"key":"10.1016\/j.brainres.2022.148133_b0115","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s12975-011-0070-8","article-title":"Inflammation of the choroid plexus and ependymal layer of the ventricle following intraventricular hemorrhage","volume":"2","author":"Simard","year":"2011","journal-title":"Transl. Stroke Res."},{"key":"10.1016\/j.brainres.2022.148133_b0120","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1006\/exnr.1998.6969","article-title":"Evidence that oxidative stress is associated with the pathophysiology of inherited hydrocephalus in the H-Tx rat model","volume":"155","author":"Socci","year":"1999","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainres.2022.148133_b0130","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1159\/000366058","article-title":"Altered expression of aquaporin 1 and 5 in the choroid plexus following preterm intraventricular hemorrhage","volume":"36","author":"Sveinsdottir","year":"2014","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.brainres.2022.148133_b0135","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1038\/mp.2017.171","article-title":"Tau-mediated iron export prevents ferroptotic damage after ischemic stroke","volume":"22","author":"Tuo","year":"2017","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainres.2022.148133_b0140","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s00213-001-0979-9","article-title":"Infralimbic kappa opioid and muscarinic M1 receptor interactions in the concurrent modulation of anxiety and memory","volume":"160","author":"Wall","year":"2002","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.brainres.2022.148133_b0145","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S1474-4422(05)70283-0","article-title":"Mechanisms of brain injury after intracerebral haemorrhage","volume":"5","author":"Xi","year":"2006","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.brainres.2022.148133_b0150","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/cdd.2015.158","article-title":"Ferroptosis: process and function","volume":"23","author":"Xie","year":"2016","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.brainres.2022.148133_b0155","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1007\/s12035-021-02706-1","article-title":"COX-2\/PGE2 Pathway Inhibits the Ferroptosis Induced by Cerebral Ischemia Reperfusion","volume":"59","author":"Xu","year":"2022","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.brainres.2022.148133_b0160","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.chembiol.2008.02.010","article-title":"Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells","volume":"15","author":"Yang","year":"2008","journal-title":"Chem. Biol."},{"key":"10.1016\/j.brainres.2022.148133_b0165","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.cell.2013.12.010","article-title":"Regulation of ferroptotic cancer cell death by GPX4","volume":"156","author":"Yang","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.brainres.2022.148133_b0170","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1016\/j.bbrc.2016.08.124","article-title":"Identification of ACSL4 as a biomarker and contributor of ferroptosis","volume":"478","author":"Yuan","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.brainres.2022.148133_b0175","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/s41419-021-04490-1","article-title":"Double-edge sword roles of iron in driving energy production versus instigating ferroptosis","volume":"13","author":"Zhang","year":"2022","journal-title":"Cell Death Dis."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899322003572?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899322003572?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T17:07:27Z","timestamp":1762103247000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899322003572"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":33,"alternative-id":["S0006899322003572"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2022.148133","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The induction of ferroptosis in posthemorrhagic hydrocephalus","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2022.148133","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"148133"}}