{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T16:50:53Z","timestamp":1791651053735,"version":"4.3.4"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.brainres.2025.149530","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T04:04:39Z","timestamp":1740456279000},"page":"149530","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["MIMI-ONET: Multi-Modal image augmentation via Butterfly Optimized neural network for Huntington DiseaseDetection"],"prefix":"10.1016","volume":"1855","author":[{"given":"S.","family":"Amudaria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.Joseph","family":"Jawhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.brainres.2025.149530_b0005","doi-asserted-by":"crossref","first-page":"7166","DOI":"10.1038\/s41598-022-11012-2","article-title":"Interpretability and fairness evaluation of deep learning models on MIMIC-IV dataset","volume":"12","author":"Meng","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.brainres.2025.149530_b0010","first-page":"4784","article-title":"Early Warning Signs of Parkinson\u2019s Disease Prediction Using Machine Learning Technique","author":"Mall","year":"2022","journal-title":"Journal of Pharmaceutical Negative Results"},{"key":"10.1016\/j.brainres.2025.149530_b0015","doi-asserted-by":"crossref","DOI":"10.1109\/JSEN.2024.3373429","article-title":"DEEP-CARDIO: Recommendation System for Cardiovascular Disease Prediction using IOT Network","author":"Yashudas","year":"2024","journal-title":"IEEE Sens. J."},{"issue":"49","key":"10.1016\/j.brainres.2025.149530_b0020","doi-asserted-by":"crossref","first-page":"73809","DOI":"10.1007\/s11356-022-22830-2","article-title":"Focusing the pivotal role of nanotechnology in Huntington\u2019s disease: an insight into the recent advancements","volume":"29","author":"Singh","year":"2022","journal-title":"Environ. Sci. Pollut. Res."},{"issue":"8","key":"10.1016\/j.brainres.2025.149530_b0025","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.3390\/jpm12081222","article-title":"Using a clinical formulation to understand psychological distress in people affected by Huntington\u2019s disease: A descriptive, evidence-based model","volume":"12","author":"Dale","year":"2022","journal-title":"Journal of Personalized Medicine"},{"key":"10.1016\/j.brainres.2025.149530_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2021.101543","article-title":"The protective role of exercise against age-related neurodegeneration","volume":"74","author":"Sujkowski","year":"2022","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.brainres.2025.149530_b0035","doi-asserted-by":"crossref","DOI":"10.1177\/11795735221092517","article-title":"Current and possible future therapeutic options for Huntington\u2019s disease","volume":"14","author":"Ferguson","year":"2022","journal-title":"Journal of Central Nervous System Disease"},{"issue":"01","key":"10.1016\/j.brainres.2025.149530_b0040","first-page":"23","article-title":"Brain aneurysm detection via firefly optimized spiking neural network","volume":"01","author":"Jegatheesh","year":"2023","journal-title":"International Journal of Current Bio-Medical Engineering"},{"issue":"5","key":"10.1016\/j.brainres.2025.149530_b0045","doi-asserted-by":"crossref","DOI":"10.1088\/2057-1976\/ac0ccc","article-title":"Efficient brain tumor detection and classification using magnetic resonance imaging","volume":"7","author":"Sundarasekar","year":"2021","journal-title":"Biomed. Phys. Eng. Express"},{"issue":"1","key":"10.1016\/j.brainres.2025.149530_b0055","article-title":"Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches. Brain","volume":"5","author":"Smith","year":"2023","journal-title":"Communications"},{"key":"10.1016\/j.brainres.2025.149530_b0060","series-title":"In 2022 3rd International Conference on Innovations in Computer Science & Software Engineering (ICONICS)","first-page":"1","article-title":"December. Genetic Testing of Huntington\u2019s Disease by Facial Examination of a Mankind using AI Programs","author":"Feroze","year":"2022"},{"issue":"19","key":"10.1016\/j.brainres.2025.149530_b0065","doi-asserted-by":"crossref","first-page":"7308","DOI":"10.3390\/s22197308","article-title":"Recent advances in counterfeit art, document, photo, hologram, and currency detection using hyperspectral imaging","volume":"22","author":"Huang","year":"2022","journal-title":"Sensors"},{"key":"10.1016\/j.brainres.2025.149530_b0070","doi-asserted-by":"crossref","DOI":"10.3389\/fdgth.2022.836851","article-title":"OCT and OCT angiography offer new insights and opportunities in schizophrenia research and treatment","volume":"4","author":"Green","year":"2022","journal-title":"Front. Digital Health"},{"key":"10.1016\/j.brainres.2025.149530_b0075","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.patrec.2022.04.027","article-title":"Twitter sentiment analysis using ensemble based deep learning model towards COVID-19 in India and European countries","volume":"158","author":"Sunitha","year":"2022","journal-title":"Pattern Recogn. Lett."},{"key":"10.1016\/j.brainres.2025.149530_b0080","doi-asserted-by":"crossref","unstructured":"Paul, D.N., 2022. We Were Not the Savages, First Nations History: Collision Between European and Native American Civilizations. Fernwood publishing. https:\/\/doi.org\/10.2307\/1185579.","DOI":"10.2307\/1185579"},{"issue":"6537","key":"10.1016\/j.brainres.2025.149530_b0085","doi-asserted-by":"crossref","DOI":"10.1126\/science.abf7117","article-title":"Haplotype-resolved diverse human genomes and integrated analysis of structural variation","volume":"372","author":"Ebert","year":"2021","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.brainres.2025.149530_b0095","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1109\/MSP.2021.3128348","article-title":"Deep learning in neuroimaging: Promises and challenges","volume":"39","author":"Yan","year":"2022","journal-title":"IEEE Signal Process Mag."},{"key":"10.1016\/j.brainres.2025.149530_b0100","article-title":"Deep learning for rare disease: A scoping review","volume":"104227","author":"Lee","year":"2022","journal-title":"J. Biomed. Inform."},{"key":"10.1016\/j.brainres.2025.149530_b0105","series-title":"In MEDINFO 2019: Health and Wellbeing e-Networks for All","first-page":"477","article-title":"A deep learning-based approach for gait analysis in Huntington disease","author":"Zhang","year":"2019"},{"key":"10.1016\/j.brainres.2025.149530_b0110","series-title":"In 2019 IEEE 31st International Conference on Tools with Artificial Intelligence (ICTAI)","first-page":"1659","article-title":"November. An Automatic Method for Identifying Huntington's Disease using Gait Dynamics","author":"Felix","year":"2019"},{"issue":"6","key":"10.1016\/j.brainres.2025.149530_b0120","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1002\/jmri.26983","article-title":"Deep\u2010learning\u2010based preprocessing for quantitative myocardial perfusion MRI","volume":"51","author":"Scannell","year":"2020","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.brainres.2025.149530_b0125","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.ibneur.2022.10.014","article-title":"A deep learning framework integrating MRI image preprocessing methods for brain tumor segmentation and classification","volume":"13","author":"Dang","year":"2022","journal-title":"IBRO Neuroscience Reports"},{"issue":"90","key":"10.1016\/j.brainres.2025.149530_b0130","first-page":"604","article-title":"Prediction of neurodegenerative disease using brain image analysis with multilinear principal component analysis and quadratic discriminant analysis","volume":"9","author":"Gopalsamy","year":"2022","journal-title":"International Journal of Advanced Technology and Engineering Exploration"},{"issue":"3","key":"10.1016\/j.brainres.2025.149530_b0135","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1093\/brain\/awab367","article-title":"Imbalanced basal ganglia connectivity is associated with motor deficits and apathy in Huntington\u2019s disease","volume":"145","author":"Nair","year":"2022","journal-title":"Brain"},{"key":"10.1016\/j.brainres.2025.149530_b0140","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.77568","article-title":"A novel rhesus macaque model of Huntington\u2019s disease recapitulates key neuropathological changes along with motor and cognitive decline","volume":"11","author":"Weiss","year":"2022","journal-title":"Elife"},{"key":"10.1016\/j.brainres.2025.149530_b0145","author":"Ouwerkerk","year":"2023","journal-title":"Machine Learning in Huntington's Disease: Exploring the Enroll-HD Dataset for Prognosis & Driving Capability Prediction."},{"key":"10.1016\/j.brainres.2025.149530_b0150","doi-asserted-by":"crossref","unstructured":"Maddury, S., 2023. Automated Huntington's Disease Prognosis via Biomedical Signals and Shallow Machine Learning. arXiv preprint arXiv:2302.03605. https:\/\/doi.org\/10.3389\/frsip.2024.1321861.","DOI":"10.3389\/frsip.2024.1321861"},{"issue":"5","key":"10.1016\/j.brainres.2025.149530_b0155","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1002\/ana.25709","article-title":"Robust markers and sample sizes for multicenter trials of Huntington disease","volume":"87","author":"Wijeratne","year":"2020","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.brainres.2025.149530_b0160","doi-asserted-by":"crossref","first-page":"11585","DOI":"10.1109\/ACCESS.2021.3049479","article-title":"Residual learning of cycle-GAN for seismic data denoising","volume":"9","author":"Li","year":"2021","journal-title":"IEEE Access"},{"key":"10.1016\/j.brainres.2025.149530_b0170","series-title":"April. Machine Learning-Based Brain Disease Classification Using EEG and MEG Signals","first-page":"487","author":"Ahilan","year":"2023"},{"key":"10.1016\/j.brainres.2025.149530_b0185","doi-asserted-by":"crossref","unstructured":"D. S. Dakshina, Dr. P. Jayapriya and R. Kala, 2023, Saree texture analysis and classification via deep learning framework, International Journal of Data Science and Artificial Intelligence, 01(01), 20-25.","DOI":"10.66135\/ijdsai0101p003"},{"issue":"10","key":"10.1016\/j.brainres.2025.149530_b0190","doi-asserted-by":"crossref","first-page":"829","DOI":"10.32985\/ijeces.15.10.2","article-title":"Mask FORD-NET: Efficient Detection of Digital Image Forgery using Hybrid REG-NET based Mask-RCNN","volume":"15","author":"Whitin","year":"2024","journal-title":"International Journal of Electrical and Computer Engineering Systems"},{"issue":"10","key":"10.1016\/j.brainres.2025.149530_b0195","doi-asserted-by":"crossref","first-page":"7419","DOI":"10.1007\/s11760-024-03404-w","article-title":"LV-YOLO: Logistic vehicle speed detection and counting using deep learning based YOLO network","volume":"18","author":"Rani","year":"2024","journal-title":"SIViP"},{"issue":"1","key":"10.1016\/j.brainres.2025.149530_b0200","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s11760-023-02710-z","article-title":"YOLOAPPLE: Augment Yolov3 deep learning algorithm for apple fruit quality detection","volume":"18","author":"Karthikeyan","year":"2024","journal-title":"SIViP"},{"key":"10.1016\/j.brainres.2025.149530_b0205","article-title":"Cooperative Path Planning of Multiple Unmanned Aerial Vehicles Using Cylinder Vector Particle Swarm Optimization with Gene Targeting","author":"Huang","year":"2025","journal-title":"IEEE Sens. J."},{"key":"10.1016\/j.brainres.2025.149530_b0210","article-title":"A Broad Sparse Fine-Grained Image Classification Model Based on Dictionary Selection Strategy","author":"Zheng","year":"2023","journal-title":"IEEE Trans. Reliab."},{"key":"10.1016\/j.brainres.2025.149530_b0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.ins.2023.119892","article-title":"An effective and robust genetic algorithm with hybrid multi-strategy and mechanism for airport gate allocation","volume":"654","author":"Zhu","year":"2024","journal-title":"Inf. Sci."},{"key":"10.1016\/j.brainres.2025.149530_b0230","first-page":"1","article-title":"A novel and proposed triad machine learning-based framework for the prognosis of Huntington\u2019s disease","author":"Deepak","year":"2024","journal-title":"Int. J. Inf. Technol."},{"key":"10.1016\/j.brainres.2025.149530_b0050","article-title":"Theoretical design for covering Engeletin with functionalized nanostructure-lipid carriers as neuroprotective agents against Huntington\u2019s disease via the nasal-brain route","volume":"14","author":"Singla","year":"2023","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.brainres.2025.149530_b0115","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3906\/elk-1904-172","article-title":"Applying deep learning models to structural MRI for stage prediction of Alzheimer's disease","volume":"28","author":"Y\u0130\u011e\u0130T, A., I\u015fik, Z.","year":"2020","journal-title":"Turk. J. Electr. Eng. Comput. Sci."},{"key":"10.1016\/j.brainres.2025.149530_b0165","series-title":"Inproceedings of the IEEE Conference on Computer Vision and Pattern Recognition","first-page":"8789","article-title":"Stargan: Unified generative adversarial networks for multi-domain image-to-image translation","author":"Choi","year":"2018"},{"issue":"03","key":"10.1016\/j.brainres.2025.149530_b0175","doi-asserted-by":"crossref","first-page":"68","DOI":"10.66135\/ijdsai0203p001","article-title":"DEEP LEARNING BASED LSTM-GAN APPROACH FOR INTRUSION DETECTION IN CLOUD ENVIRONMENT","volume":"02","author":"Rose","year":"2024","journal-title":"International Journal of Data Science and Artificial Intelligence"},{"issue":"01","key":"10.1016\/j.brainres.2025.149530_b0180","first-page":"30","article-title":"Primary open-angle glaucoma severity prediction using deep learning technique","volume":"01","author":"Dr","year":"2023","journal-title":"International Journal of Current Bio-Medical Engineering"},{"key":"10.1016\/j.brainres.2025.149530_b0090","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.comnet.2019.01.028","article-title":"Real time violence detection framework for football stadium comprising of big data analysis and deep learning through bidirectional LSTM","volume":"151","author":"Fenil","year":"2019","journal-title":"Comput. Netw."},{"key":"10.1016\/j.brainres.2025.149530_b0220","article-title":"Quantum differential evolutionary algorithm with quantum-adaptive mutation strategy and population state evaluation framework for high-dimensional problems","volume":"120787","author":"Deng","year":"2024","journal-title":"Inf. Sci."},{"key":"10.1016\/j.brainres.2025.149530_b0225","doi-asserted-by":"crossref","DOI":"10.1109\/TWC.2024.3479149","article-title":"APDPFL: Anti-poisoning attack decentralized privacy enhanced federated learning scheme for flight operation data sharing","author":"Li","year":"2024","journal-title":"IEEE Trans. Wirel. Commun."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899325000885?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899325000885?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T16:16:12Z","timestamp":1791648972000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899325000885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":46,"alternative-id":["S0006899325000885"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2025.149530","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MIMI-ONET: Multi-Modal image augmentation via Butterfly Optimized neural network for Huntington DiseaseDetection","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2025.149530","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"149530"}}