{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T06:38:49Z","timestamp":1781246329619,"version":"3.54.1"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005047","name":"Natural Science Foundation of Liaoning Province","doi-asserted-by":"publisher","award":["2021-MS-155"],"award-info":[{"award-number":["2021-MS-155"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.brainres.2025.149609","type":"journal-article","created":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T20:37:53Z","timestamp":1743712673000},"page":"149609","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Protection of dauricine and daurisoline on PC12 cells damaged by glutamate or A\u03b225-35"],"prefix":"10.1016","volume":"1857","author":[{"given":"Xiao-Han","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song-Yao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Na","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-Lian","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2025.149609_b0005","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.ijbiomac.2020.11.192","article-title":"Review on Alzheimer\u2019s disease: inhibition of amyloid beta and tau tangle formation","volume":"167","author":"Ashrafian","year":"2021","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.brainres.2025.149609_b0010","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/jnc.14471","article-title":"Mitochondria, lysosomes, and dysfunction: their meaning in neurodegeneration","volume":"147","author":"Audano","year":"2018","journal-title":"J. Neurochem."},{"issue":"3","key":"10.1016\/j.brainres.2025.149609_b0015","first-page":"276","article-title":"Inflammation, apoptosis, and Alzheimer\u2019s disease","volume":"8","author":"Bamberger","year":"2002","journal-title":"Neuroscientist"},{"issue":"3","key":"10.1016\/j.brainres.2025.149609_b0020","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.jtcme.2020.03.002","article-title":"A review on plants and herbal components with antiarrhythmic activities and their interaction with current cardiac drugs","volume":"10","author":"Beik","year":"2020","journal-title":"J. Tradit. Complement. Med."},{"issue":"15","key":"10.1016\/j.brainres.2025.149609_b0025","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1007\/s00018-013-1550-7","article-title":"Neuronal calcium signaling: function and dysfunction","volume":"71","author":"Brini","year":"2014","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.brainres.2025.149609_b0030","article-title":"Dauricine attenuates spatial memory impairment and Alzheimer-like pathologies by enhancing mitochondrial function in a mouse model of Alzheimer\u2019s disease","volume":"8","author":"Chen","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.brainres.2025.149609_b0035","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.pharmthera.2018.11.006","article-title":"Synaptic dysfunction in Alzheimer\u2019s disease: mechanisms and therapeutic strategies","volume":"195","author":"Chen","year":"2019","journal-title":"Pharmacol. Ther."},{"issue":"1","key":"10.1016\/j.brainres.2025.149609_b0040","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s13024-020-00391-7","article-title":"Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer\u2019s disease","volume":"15","author":"Guo","year":"2020","journal-title":"Mol. Neurodegener."},{"issue":"1","key":"10.1016\/j.brainres.2025.149609_b0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2020.112437","article-title":"TRIM27-mediated ubiquitination of PPAR\u03b3 promotes glutamate-induced cell apoptosis and inflammation","volume":"400","author":"Hao","year":"2021","journal-title":"Exp. Cell Res."},{"issue":"3","key":"10.1016\/j.brainres.2025.149609_b0050","doi-asserted-by":"crossref","first-page":"553","DOI":"10.3390\/molecules25030553","article-title":"The effect of protein-rich extract frombombyx batryticatusagainst glutamate-damaged PC12 cells via regulating \u03b3-aminobutyric acid signaling pathway","volume":"25","author":"He","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.brainres.2025.149609_b0055","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.758962","article-title":"Dauricine attenuates vascular endothelial inflammation through inhibiting NF-\u03baB pathway","volume":"12","author":"Hu","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.brainres.2025.149609_b0060","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00401-009-0486-3","article-title":"Mechanisms of tau-induced neurodegeneration","volume":"118","author":"Iqbal","year":"2009","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.brainres.2025.149609_b0065","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.procbio.2022.07.026","article-title":"\u03b1-bisabolol \u03b2-D-fucopyranoside inhibits \u03b2-amyloid (A\u03b2)25-35 induced oxidative stress in Neuro-2a cells via antioxidant approaches","volume":"121","author":"Jeyakumar","year":"2022","journal-title":"Process Biochem."},{"issue":"9201","key":"10.1016\/j.brainres.2025.149609_b0070","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0140-6736(99)05226-5","article-title":"Mitochondrial respiratory chain disorders II: neurodegenerative disorders and nuclear gene defects","volume":"355","author":"Leonard","year":"2000","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.brainres.2025.149609_b0075","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1139\/Y07-056","article-title":"Neuroprotective effect of dauricine in cortical neuron culture exposed to hypoxia and hypoglycemia: involvement of correcting perturbed calcium homeostasis","volume":"85","author":"Li","year":"2007","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.brainres.2025.149609_b0080","doi-asserted-by":"crossref","DOI":"10.2174\/0115680096282997240101192452","article-title":"Dauricine inhibits non-small cell lung cancer development by regulating PTEN\/AKT\/mTOR and Ras\/MEK1\/2\/ERK1\/2 pathways in a FLT4-dependent manner","author":"Liang","year":"2024","journal-title":"Curr. Cancer Drug Targets"},{"issue":"3","key":"10.1016\/j.brainres.2025.149609_b0085","first-page":"171","article-title":"Protective effects of (-)-S.R-daurisoline on neuronal injury in rat primary cortical cultures","volume":"33","author":"Liu","year":"1998","journal-title":"Yao Xue Xue Bao"},{"issue":"1","key":"10.1016\/j.brainres.2025.149609_b0090","first-page":"21","article-title":"l-S.R-daurisoline protects cultured hippocampal neurons against glutamate neurotoxicity by reducing nitric oxide production","volume":"20","author":"Liu","year":"1999","journal-title":"Zhongguo Yao Li Xue Bao"},{"issue":"1\u20132","key":"10.1016\/j.brainres.2025.149609_b0095","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.cell.2014.12.019","article-title":"Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration","volume":"160","author":"Liu","year":"2015","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.brainres.2025.149609_b0100","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1007\/s13311-023-01356-6","article-title":"Ferulic acid improves synaptic plasticity and cognitive impairments by alleviating the PP2B\/DARPP-32\/PP1 axis-mediated STEP increase and A\u03b2 Burden in Alzheimer\u2019s disease","volume":"20","author":"Mahaman","year":"2023","journal-title":"Neurotherapeutics"},{"issue":"7","key":"10.1016\/j.brainres.2025.149609_b0105","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1007\/s10571-010-9537-5","article-title":"Protective effects of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via antioxidant mechanisms and Ca(2+) antagonism","volume":"30","author":"Mao","year":"2010","journal-title":"Cell. Mol. Neurobiol."},{"issue":"10","key":"10.1016\/j.brainres.2025.149609_b0110","doi-asserted-by":"crossref","DOI":"10.1111\/jfbc.14303","article-title":"Protective effects of Liensinine, Isoliensinine, and Neferine on PC12 cells injured by amyloid-\u03b2","volume":"46","author":"Meng","year":"2022","journal-title":"J. Food Biochem."},{"key":"10.1016\/j.brainres.2025.149609_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.117982","article-title":"Therapeutic potential of CB1R activation by Qingyangshen glycoside M1 for seizure relief","volume":"327","author":"Mu","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"19","key":"10.1016\/j.brainres.2025.149609_b0120","article-title":"Calmodulin binding proteins and Alzheimer\u2019s disease: biomarkers, regulatory enzymes and receptors that are regulated by calmodulin","volume":"21","author":"O'Day","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.brainres.2025.149609_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2021.174461","article-title":"Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells","volume":"914","author":"Peng","year":"2022","journal-title":"Eur. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.brainres.2025.149609_b0130","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.brainres.2005.07.032","article-title":"Effects of N-acetylcysteine amide (NACA), a novel thiol antioxidant against glutamate-induced cytotoxicity in neuronal cell line PC12","volume":"1056","author":"Penugonda","year":"2005","journal-title":"Brain Res."},{"issue":"50","key":"10.1016\/j.brainres.2025.149609_b0135","doi-asserted-by":"crossref","first-page":"6407","DOI":"10.1038\/onc.2008.308","article-title":"Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis","volume":"27","author":"Pinton","year":"2008","journal-title":"Oncogene"},{"issue":"1","key":"10.1016\/j.brainres.2025.149609_b0140","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s13024-022-00545-9","article-title":"CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer\u2019s disease","volume":"17","author":"Puntambekar","year":"2022","journal-title":"Mol. Neurodegener."},{"issue":"12","key":"10.1016\/j.brainres.2025.149609_b0145","first-page":"1086","article-title":"Cardiovascular pharmacological effects of bisbenzylisoquinoline alkaloid derivatives","volume":"23","author":"Qian","year":"2002","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.brainres.2025.149609_b0150","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.abb.2019.03.018","article-title":"Dauricine negatively regulates lipopolysaccharide- or cecal ligation and puncture-induced inflammatory response via NF-\u03baB inactivation","volume":"666","author":"Qiao","year":"2019","journal-title":"Arch. Biochem. Biophys."},{"issue":"7","key":"10.1016\/j.brainres.2025.149609_b0155","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22073701","article-title":"A highly selective in vitro JNK3 inhibitor, FMU200, restores mitochondrial membrane potential and reduces oxidative stress and apoptosis in SH-SY5Y cells","volume":"22","author":"Rehfeldt","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.brainres.2025.149609_b0160","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24043969","article-title":"Neuroprotective effects of ethanol extract of Polyscias fruticosa (EEPF) against glutamate-mediated neuronal toxicity in HT22 Cells","volume":"24","author":"Selvaraj","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"13","key":"10.1016\/j.brainres.2025.149609_b0165","first-page":"1371","article-title":"Cyclic nucleotides signaling and phosphodiesterase inhibition: defying Alzheimer\u2019s disease","volume":"21","author":"Sharma","year":"2020","journal-title":"Curr. Drug Targets"},{"issue":"5","key":"10.1016\/j.brainres.2025.149609_b0170","first-page":"597","article-title":"The amyloid beta ion channel hypothesis of Alzheimer\u2019s disease","volume":"3","author":"Shirwany","year":"2007","journal-title":"Neuropsychiatr. Dis. Treat."},{"issue":"8","key":"10.1016\/j.brainres.2025.149609_b0175","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24081583","article-title":"Oxidative stress: a key modulator in neurodegenerative diseases","volume":"24","author":"Singh","year":"2019","journal-title":"Molecules"},{"issue":"17","key":"10.1016\/j.brainres.2025.149609_b0180","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22179207","article-title":"Tau protein interaction partners and their roles in Alzheimer\u2019s disease and other tauopathies","volume":"22","author":"Sinsky","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.brainres.2025.149609_b0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neurobiolaging.2017.09.007","article-title":"Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer\u2019s disease Braak stages: a quantitative study in humans","volume":"61","author":"Theofilas","year":"2018","journal-title":"Neurobiol. Aging"},{"issue":"19","key":"10.1016\/j.brainres.2025.149609_b0190","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231911025","article-title":"Molecular mechanisms underlying Ca(2+)\/calmodulin-dependent protein kinase Kinase signal transduction","volume":"23","author":"Tokumitsu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.brainres.2025.149609_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2019.117237","article-title":"Antioxidative and antiapoptosis: neuroprotective effects of dauricine in Alzheimer\u2019s disease models","volume":"243","author":"Wang","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.brainres.2025.149609_b0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.104517","article-title":"Analgesic bisbenzylisoquinoline alkaloids from the rhizoma of Menispermum dauricum DC","volume":"107","author":"Wei","year":"2021","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.brainres.2025.149609_b0205","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.talanta.2015.07.023","article-title":"A sensitive and selective UPLC-MS\/MS method for simultaneous determination of 10 alkaloids from Rhizoma Menispermi in rat plasma and its application to a pharmacokinetic study","volume":"144","author":"Wei","year":"2015","journal-title":"Talanta"},{"key":"10.1016\/j.brainres.2025.149609_b0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117560","article-title":"An alkaloid from Menispermum dauricum, dauricine mediates Ca(2+) influx and inhibits NF-\u03baB pathway to protect chondrocytes from IL-1\u03b2-induced inflammation and catabolism","volume":"321","author":"Xia","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.brainres.2025.149609_b0215","doi-asserted-by":"crossref","first-page":"18586","DOI":"10.1038\/s41598-023-45878-7","article-title":"Moschus ameliorates glutamate-induced cellular damage by regulating autophagy and apoptosis pathway","volume":"13","author":"Xie","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.brainres.2025.149609_b0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2023.116613","article-title":"Dauricine alleviates cognitive impairment in Alzheimer\u2019s disease mice induced by D-galactose and AlCl(3) via the Ca(2+)\/CaM pathway","volume":"474","author":"Xue","year":"2023","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"2","key":"10.1016\/j.brainres.2025.149609_b0225","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1142\/S0192415X10007865","article-title":"Neuroprotective effect of dauricine after transient middle cerebral artery occlusion in rats: involvement of Bcl-2 family proteins","volume":"38","author":"Yang","year":"2010","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.brainres.2025.149609_b0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2024.116113","article-title":"Daurisoline suppresses glioma progression by inhibiting autophagy through PI3K\/AKT\/mTOR pathway and increases TMZ sensitivity","volume":"223","author":"Yin","year":"2024","journal-title":"Biochem. Pharmacol."},{"issue":"3","key":"10.1016\/j.brainres.2025.149609_b0235","first-page":"1406","article-title":"Protective roles of isoastilbin against Alzheimer\u2019s disease via Nrf2\u2013mediated antioxidation and anti\u2013apoptosis","volume":"43","author":"Yu","year":"2019","journal-title":"Int. J. Mol. Med."},{"issue":"6","key":"10.1016\/j.brainres.2025.149609_b0240","doi-asserted-by":"crossref","DOI":"10.1111\/acel.13380","article-title":"Neuronal loss and microgliosis are restricted to the core of A\u03b2 deposits in mouse models of Alzheimer\u2019s disease","volume":"20","author":"Zhang","year":"2021","journal-title":"Aging Cell"},{"issue":"1","key":"10.1016\/j.brainres.2025.149609_b0245","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1186\/s13018-023-03717-5","article-title":"Daurisoline attenuates H2O2-induced chondrocyte autophagy by activating the PI3K\/Akt\/mTOR signaling pathway","volume":"18","author":"Zhang","year":"2023","journal-title":"J. Orthop. Surg. Res."},{"key":"10.1016\/j.brainres.2025.149609_b0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.108714","article-title":"Daurisoline alleviated experimental colitis in vivo and in vitro: Involvement of NF-\u03baB and Wnt\/\u03b2-Catenin pathway","volume":"108","author":"Zhou","year":"2022","journal-title":"Int. Immunopharmacol."},{"issue":"5","key":"10.1016\/j.brainres.2025.149609_b0255","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1007\/s10787-023-01291-0","article-title":"Oxymatrine-mediated prevention of amyloid \u03b2-peptide-induced apoptosis on Alzheimer\u2019s model PC12 cells: in vitro cell culture studies and in vivo cognitive assessment in rats","volume":"31","author":"Zhu","year":"2023","journal-title":"Inflammopharmacology"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899325001684?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899325001684?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:19:33Z","timestamp":1777868373000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899325001684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":51,"alternative-id":["S0006899325001684"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2025.149609","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protection of dauricine and daurisoline on PC12 cells damaged by glutamate or A\u03b225-35","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2025.149609","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"149609"}}