{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T06:03:12Z","timestamp":1785304992565,"version":"3.55.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100019649","name":"Chengdu Medical College Sichuan Provincial Key Laboratory of Development and Regeneration","doi-asserted-by":"publisher","award":["24FYYZS07"],"award-info":[{"award-number":["24FYYZS07"]}],"id":[{"id":"10.13039\/501100019649","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81901521"],"award-info":[{"award-number":["81901521"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2025NSFSC2253"],"award-info":[{"award-number":["2025NSFSC2253"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.brainres.2025.149917","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T14:50:23Z","timestamp":1756565423000},"page":"149917","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["The SIRT1 activator SRT2104 mitigates hypoxia-induced white matter injury in neonatal mice"],"prefix":"10.1016","volume":"1866","author":[{"given":"Xinyu","family":"Wei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junrong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0854-4988","authenticated-orcid":false,"given":"Yantang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6685-2634","authenticated-orcid":false,"given":"Yan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainres.2025.149917_b0005","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1523\/JNEUROSCI.21-04-01302.2001","article-title":"Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury","volume":"21","author":"Back","year":"2001","journal-title":"J Neurosci."},{"key":"10.1016\/j.brainres.2025.149917_b0010","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1523\/JNEUROSCI.22-02-00455.2002","article-title":"Selective vulnerability of late oligodendrocyte progenitors to hypoxia-ischemia","volume":"22","author":"Back","year":"2002","journal-title":"J Neurosci."},{"key":"10.1016\/j.brainres.2025.149917_b0015","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s00401-017-1718-6","article-title":"White matter injury in the preterm infant: pathology and mechanisms","volume":"134","author":"Back","year":"2017","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.brainres.2025.149917_b0020","doi-asserted-by":"crossref","unstructured":"Bell, E.F., Hintz, S.R., Hansen, N.I., Bann, C.M., Wyckoff, M.H., DeMauro, S.B., Walsh, M.C., Vohr, B.R., Stoll, B.J., Carlo, W.A., Van Meurs, K.P., Rysavy, M.A., Patel, R.M., Merhar, S.L., Sanchez, P.J., Laptook, A.R., Hibbs, A.M., Cotten, C.M., D'Angio, C.T., Winter, S., Fuller, J., Das, A., Eunice Kennedy Shriver National Institute of Child, H., Human Development Neonatal Research, N., 2022. Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013-2018. JAMA. 327, 248-263.","DOI":"10.1097\/01.aoa.0000891644.03402.e8"},{"key":"10.1016\/j.brainres.2025.149917_b0025","doi-asserted-by":"crossref","first-page":"2815","DOI":"10.1007\/s12035-015-9158-6","article-title":"SIRT1 and Neural Cell Fate Determination","volume":"53","author":"Cai","year":"2016","journal-title":"Mol Neurobiol."},{"key":"10.1016\/j.brainres.2025.149917_b0030","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.bbagrm.2010.06.005","article-title":"Sirtuin activators: designing molecules to extend life span","volume":"1799","author":"Camins","year":"2010","journal-title":"Biochim Biophys Acta."},{"key":"10.1016\/j.brainres.2025.149917_b0035","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.tem.2013.12.001","article-title":"SIRT1 and other sirtuins in metabolism","volume":"25","author":"Chang","year":"2014","journal-title":"Trends Endocrinol Metab."},{"key":"10.1016\/j.brainres.2025.149917_b0040","doi-asserted-by":"crossref","first-page":"5521","DOI":"10.1038\/s41598-024-55923-8","article-title":"Emerging roles of SIRT1 activator, SRT2104, in disease treatment","volume":"14","author":"Chang","year":"2024","journal-title":"Sci Rep."},{"key":"10.1016\/j.brainres.2025.149917_b0045","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.1794-23.2024","article-title":"Oligodendrocyte Maturation Alters the Cell Death Mechanisms That Cause Demyelination","volume":"44","author":"Chapman","year":"2024","journal-title":"J Neurosci."},{"key":"10.1016\/j.brainres.2025.149917_b0050","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jneuroim.2014.02.001","article-title":"Sirtuin 1 attenuates oxidative stress via upregulation of superoxide dismutase 2 and catalase in astrocytes","volume":"269","author":"Cheng","year":"2014","journal-title":"J Neuroimmunol."},{"key":"10.1016\/j.brainres.2025.149917_b0055","first-page":"71","article-title":"Oligodendrocyte, Astrocyte, and Microglia Crosstalk in Myelin Development, Damage, and Repair","volume":"4","author":"Domingues","year":"2016","journal-title":"Front Cell Dev Biol."},{"key":"10.1016\/j.brainres.2025.149917_b0060","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1007\/s10571-022-01288-3","article-title":"Research Progress on the Role of Sirtuin 1 in Cerebral Ischemia","volume":"43","author":"Fangma","year":"2023","journal-title":"Cell Mol Neurobiol."},{"key":"10.1016\/j.brainres.2025.149917_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.147236","article-title":"Sirt1 activator SRT2104 protects against oxygen-glucose deprivation\/reoxygenation-induced injury via regulating microglia polarization by modulating Sirt1\/NF-kappaB pathway","volume":"1753","author":"Fu","year":"2021","journal-title":"Brain Res."},{"key":"10.1016\/j.brainres.2025.149917_b0070","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1146\/annurev.pathol.4.110807.092250","article-title":"Mammalian sirtuins: biological insights and disease relevance","volume":"5","author":"Haigis","year":"2010","journal-title":"Annu Rev Pathol."},{"key":"10.1016\/j.brainres.2025.149917_b0075","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.bbrc.2021.01.095","article-title":"SIRT1 decelerates morphological processing of oligodendrocyte cell lines and regulates the expression of cytoskeleton-related oligodendrocyte proteins","volume":"546","author":"Hisahara","year":"2021","journal-title":"Biochem Biophys Res Commun."},{"key":"10.1016\/j.brainres.2025.149917_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101747","article-title":"Meteorin-like protein attenuates doxorubicin-induced cardiotoxicity via activating cAMP\/PKA\/SIRT1 pathway","volume":"37","author":"Hu","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.brainres.2025.149917_b0085","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.freeradbiomed.2013.07.029","article-title":"Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-beta1 by activating the Nrf2\/ARE pathway in glomerular mesangial cells","volume":"65","author":"Huang","year":"2013","journal-title":"Free Radic Biol Med."},{"key":"10.1016\/j.brainres.2025.149917_b0090","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.mce.2014.08.014","article-title":"Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-beta1 in rat glomerular messangial cells","volume":"399","author":"Huang","year":"2015","journal-title":"Mol Cell Endocrinol."},{"key":"10.1016\/j.brainres.2025.149917_b0095","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1111\/pcmr.12808","article-title":"Tyrosinase-catalyzed oxidation of resveratrol produces a highly reactive ortho-quinone: Implications for melanocyte toxicity","volume":"32","author":"Ito","year":"2019","journal-title":"Pigment Cell Melanoma Res."},{"key":"10.1016\/j.brainres.2025.149917_b0100","doi-asserted-by":"crossref","first-page":"13866","DOI":"10.1038\/ncomms13866","article-title":"Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury","volume":"7","author":"Jablonska","year":"2016","journal-title":"Nat Commun."},{"key":"10.1016\/j.brainres.2025.149917_b0105","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1002\/acn3.135","article-title":"Sirtuin 1 activator SRT2104 protects Huntington's disease mice","volume":"1","author":"Jiang","year":"2014","journal-title":"Ann Clin Transl Neurol."},{"key":"10.1016\/j.brainres.2025.149917_b0110","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12974-017-0841-6","article-title":"Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo","volume":"14","author":"Li","year":"2017","journal-title":"J Neuroinflammation."},{"key":"10.1016\/j.brainres.2025.149917_b0115","article-title":"Sirtuin1 in Spinal Cord Injury: Regulatory Mechanisms, Microenvironment Remodeling and Therapeutic Potential","volume":"31","author":"Li","year":"2025","journal-title":"CNS Neurosci Ther."},{"key":"10.1016\/j.brainres.2025.149917_b0120","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.14336\/AD.2020.0216","article-title":"The Critical Role of SIRT1 in Parkinson's Disease: Mechanism and Therapeutic Considerations","volume":"11","author":"Li","year":"2020","journal-title":"Aging Dis."},{"key":"10.1016\/j.brainres.2025.149917_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101771","article-title":"Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis","volume":"38","author":"Li","year":"2021","journal-title":"Redox Biol."},{"key":"10.1016\/j.brainres.2025.149917_b0130","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21218226","article-title":"Abeta-Induced Damage Memory in hCMEC\/D3 Cells Mediated by Sirtuin-1","volume":"21","author":"Liu","year":"2020","journal-title":"Int J Mol Sci."},{"key":"10.1016\/j.brainres.2025.149917_b0135","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1177\/1087057106294710","article-title":"SIRT1 modulating compounds from high-throughput screening as anti-inflammatory and insulin-sensitizing agents","volume":"11","author":"Nayagam","year":"2006","journal-title":"J Biomol Screen."},{"key":"10.1016\/j.brainres.2025.149917_b0140","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s11011-019-00488-z","article-title":"Nrf2 deficiency increases oligodendrocyte loss, demyelination, neuroinflammation and axonal damage in an MS animal model","volume":"35","author":"Nellessen","year":"2020","journal-title":"Metab Brain Dis."},{"key":"10.1016\/j.brainres.2025.149917_b0145","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/iub.47","article-title":"Resveratrol: one molecule, many targets","volume":"60","author":"Pirola","year":"2008","journal-title":"IUBMB Life."},{"key":"10.1016\/j.brainres.2025.149917_b0150","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.neulet.2019.04.007","article-title":"Regulation of sirtuin expression in autoimmune neuroinflammation: Induction of SIRT1 in oligodendrocyte progenitor cells","volume":"704","author":"Prozorovski","year":"2019","journal-title":"Neurosci Lett."},{"key":"10.1016\/j.brainres.2025.149917_b0155","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1038\/ncb2735","article-title":"Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain","volume":"15","author":"Rafalski","year":"2013","journal-title":"Nat Cell Biol."},{"key":"10.1016\/j.brainres.2025.149917_b0160","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0014-5793(03)01444-3","article-title":"Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain","volume":"556","author":"Sakamoto","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.brainres.2025.149917_b0165","doi-asserted-by":"crossref","first-page":"3235","DOI":"10.1038\/s41467-018-05656-w","article-title":"Neonatal brain injury causes cerebellar learning deficits and Purkinje cell dysfunction","volume":"9","author":"Sathyanesan","year":"2018","journal-title":"Nat Commun."},{"key":"10.1016\/j.brainres.2025.149917_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2024.115280","article-title":"The SIRT-1\/Nrf2\/HO-1 axis: Guardians of neuronal health in neurological disorders","volume":"476","author":"Sethi","year":"2025","journal-title":"Behav Brain Res."},{"key":"10.1016\/j.brainres.2025.149917_b0175","doi-asserted-by":"crossref","first-page":"619","DOI":"10.3389\/fimmu.2020.00619","article-title":"Histone Deacetylase SIRT1 Mediates C5b-9-Induced Cell Cycle in Oligodendrocytes","volume":"11","author":"Tatomir","year":"2020","journal-title":"Front Immunol."},{"key":"10.1016\/j.brainres.2025.149917_b0180","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0092-8674(01)00527-X","article-title":"hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase","volume":"107","author":"Vaziri","year":"2001","journal-title":"Cell."},{"key":"10.1016\/j.brainres.2025.149917_b0185","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S1474-4422(08)70294-1","article-title":"Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances","volume":"8","author":"Volpe","year":"2009","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.brainres.2025.149917_b0190","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1124\/dmd.104.000885","article-title":"High absorption but very low bioavailability of oral resveratrol in humans","volume":"32","author":"Walle","year":"2004","journal-title":"Drug Metab Dispos."},{"key":"10.1016\/j.brainres.2025.149917_b0195","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.freeradbiomed.2022.02.001","article-title":"Deacetylation of ZKSCAN3 by SIRT1 induces autophagy and protects SN4741 cells against MPP(+)-induced oxidative stress","volume":"181","author":"Wu","year":"2022","journal-title":"Free Radic Biol Med."},{"key":"10.1016\/j.brainres.2025.149917_b0200","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3233\/JHD-130046","article-title":"Pharmacological upregulation of PGC1alpha in oligodendrocytes: implications for Huntington's Disease","volume":"2","author":"Xiang","year":"2013","journal-title":"J Huntingtons Dis."},{"key":"10.1016\/j.brainres.2025.149917_b0205","doi-asserted-by":"crossref","first-page":"890","DOI":"10.21037\/atm-22-3789","article-title":"Activation of AMPK\/p38\/Nrf2 is involved in resveratrol alleviating myocardial ischemia-reperfusion injury in diabetic rats as an endogenous antioxidant stress feedback","volume":"10","author":"Xu","year":"2022","journal-title":"Ann Transl Med."},{"key":"10.1016\/j.brainres.2025.149917_b0210","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ijcard.2021.08.007","article-title":"Protection of the enhanced Nrf2 deacetylation and its downstream transcriptional activity by SIRT1 in myocardial ischemia\/reperfusion injury","volume":"342","author":"Xu","year":"2021","journal-title":"Int J Cardiol."},{"key":"10.1016\/j.brainres.2025.149917_b0215","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2022.886087","article-title":"Sirtuins functions in central nervous system cells under neurological disorders","volume":"13","author":"Yan","year":"2022","journal-title":"Front Physiol."},{"key":"10.1016\/j.brainres.2025.149917_b0220","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.bbadis.2016.01.019","article-title":"Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system","volume":"1862","author":"Yoon","year":"2016","journal-title":"Biochim Biophys Acta."},{"key":"10.1016\/j.brainres.2025.149917_b0225","doi-asserted-by":"crossref","unstructured":"Younge, N., Goldstein, R.F., Bann, C.M., Hintz, S.R., Patel, R.M., Smith, P.B., Bell, E.F., Rysavy, M.A., Duncan, A.F., Vohr, B.R., Das, A., Goldberg, R.N., Higgins, R.D., Cotten, C.M., Eunice Kennedy Shriver National Institute of Child, H., Human Development Neonatal Research, N., 2017. Survival and Neurodevelopmental Outcomes among Periviable Infants. N Engl J Med. 376, 617-628.","DOI":"10.1097\/01.aoa.0000521247.86996.2d"},{"key":"10.1016\/j.brainres.2025.149917_b0230","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.brainresbull.2019.05.005","article-title":"Sirt1 improves functional recovery by regulating autophagy of astrocyte and neuron after brain injury","volume":"150","author":"Zhang","year":"2019","journal-title":"Brain Res Bull."},{"key":"10.1016\/j.brainres.2025.149917_b0235","article-title":"The Sirt1\/P53 Axis in Diabetic Intervertebral Disc Degeneration Pathogenesis and Therapeutics","volume":"2019","author":"Zhang","year":"2019","journal-title":"Oxid Med Cell Longev."},{"key":"10.1016\/j.brainres.2025.149917_b0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.105103","article-title":"Role of the neurovascular unit in the process of cerebral ischemic injury","volume":"160","author":"Zhao","year":"2020","journal-title":"Pharmacol Res."},{"key":"10.1016\/j.brainres.2025.149917_b0245","article-title":"Ameliorating Mitochondrial Dysfunction of Neurons by Biomimetic Targeting Nanoparticles Mediated Mitochondrial Biogenesis to Boost the Therapy of Parkinson's Disease","volume":"10","author":"Zheng","year":"2023","journal-title":"Adv Sci (Weinh)."},{"key":"10.1016\/j.brainres.2025.149917_b0250","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/nn.3990","article-title":"GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury","volume":"18","author":"Zonouzi","year":"2015","journal-title":"Nat Neurosci."}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899325004809?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899325004809?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T04:18:34Z","timestamp":1780114714000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899325004809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":50,"alternative-id":["S0006899325004809"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2025.149917","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The SIRT1 activator SRT2104 mitigates hypoxia-induced white matter injury in neonatal mice","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2025.149917","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"149917"}}