{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:51:26Z","timestamp":1791420686634,"version":"4.3.3"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515012169"],"award-info":[{"award-number":["2024A1515012169"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010618","name":"Guangzhou University of Chinese Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010618","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","award":["2025A04J4040"],"award-info":[{"award-number":["2025A04J4040"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82205249"],"award-info":[{"award-number":["82205249"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82174483"],"award-info":[{"award-number":["82174483"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.brainres.2026.150509","type":"journal-article","created":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T11:34:08Z","timestamp":1786880048000},"page":"150509","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Single-cell reanalysis characterizes an Osmr+ astrocyte state and predicts midkine signaling to Cox6b1+ glutamatergic neurons at 24\u00a0h after traumatic brain injury"],"prefix":"10.1016","volume":"1891","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7226-3730","authenticated-orcid":false,"given":"Fu","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luxi","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8661-8921","authenticated-orcid":false,"given":"Jianan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanglei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yimin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2102-9322","authenticated-orcid":false,"given":"Shujun","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0005","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/JS9.0000000000001837","article-title":"Global, regional, and national burdens of mild traumatic brain injuries from 1990 to 2019: findings from the Global Burden of Disease Study 2019 - a cross-sectional study","volume":"111","author":"Wu","year":"2025","journal-title":"Int. J. Surg. (London, England)."},{"issue":"2","key":"10.1016\/j.brainres.2026.150509_b0010","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.70093","article-title":"Dysregulation of Rho-associated coiled-coil protein kinase1 depletes neural stem cell pool and impairs hippocampal neurogenesis after traumatic brain injury","volume":"59","author":"Yao","year":"2025","journal-title":"Cell Prolif."},{"issue":"4","key":"10.1016\/j.brainres.2026.150509_b0015","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11040974","article-title":"Chinese admission warning strategy for predicting the hospital discharge outcome in patients with traumatic brain injury","volume":"11","author":"Zheng","year":"2022","journal-title":"J. Clin. Med."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0020","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/brain\/awaa321","article-title":"The synapse in traumatic brain injury","volume":"144","author":"Jamjoom","year":"2021","journal-title":"Brain J. Neurol."},{"issue":"7","key":"10.1016\/j.brainres.2026.150509_b0025","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1016\/j.apsb.2025.05.010","article-title":"Advances in research on biomaterials and stem cell\/exosome-based strategies in the treatment of traumatic brain injury","volume":"15","author":"Chi","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.brainres.2026.150509_b0030","article-title":"Neuroprotective effects of cobalt oxide nanoparticles through mitigating oxidative stress and reactive glial responses in traumatic brain injury","volume":"35","author":"Qiu","year":"2025","journal-title":"Mater. Today Bio"},{"issue":"9","key":"10.1016\/j.brainres.2026.150509_b0035","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.tins.2025.06.009","article-title":"A functional perspective on astrocyte heterogeneity","volume":"48","author":"Kwon","year":"2025","journal-title":"Trends Neurosci."},{"issue":"9","key":"10.1016\/j.brainres.2026.150509_b0040","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.4103\/1673-5374.306064","article-title":"Astrocytes: a double-edged sword in neurodegenerative diseases","volume":"16","author":"Ding","year":"2021","journal-title":"Neural Regen. Res."},{"issue":"11","key":"10.1016\/j.brainres.2026.150509_b0045","doi-asserted-by":"crossref","DOI":"10.3390\/cells13110921","article-title":"Neurodegenerative diseases: unraveling the heterogeneity of astrocytes","volume":"13","author":"Santiago-Balmaseda","year":"2024","journal-title":"Cells"},{"issue":"17","key":"10.1016\/j.brainres.2026.150509_b0050","doi-asserted-by":"crossref","first-page":"4203","DOI":"10.1038\/s44319-025-00529-y","article-title":"Astrocyte diversity and subtypes: aligning transcriptomics with multimodal perspectives","volume":"26","author":"Hennes","year":"2025","journal-title":"EMBO Rep."},{"key":"10.1016\/j.brainres.2026.150509_b0055","article-title":"Single-nucleus transcriptomics reveals sepsis-related neurovascular dysfunction in the human hippocampus","volume":"16","author":"Liu","year":"2025","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0060","doi-asserted-by":"crossref","first-page":"6992","DOI":"10.1038\/s41467-025-61829-4","article-title":"Dual lineage origins contribute to neocortical astrocyte diversity","volume":"16","author":"Zhou","year":"2025","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15212\/bioi-2025-0073","article-title":"Mechanistic insights and therapeutic potential of quercetin in neuroprotection: a comprehensive review of pathways and clinical perspectives","volume":"6","author":"Debnath","year":"2025","journal-title":"BIO Integration."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0070","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/s41392-025-02253-4","article-title":"Mitochondria in oxidative stress, inflammation and aging: from mechanisms to therapeutic advances","volume":"10","author":"Xu","year":"2025","journal-title":"Signal Transduct. Target. Ther."},{"issue":"9","key":"10.1016\/j.brainres.2026.150509_b0080","article-title":"Acutely blocking excessive mitochondrial fission prevents chronic neurodegeneration after traumatic brain injury","volume":"5","author":"Sridharan","year":"2024","journal-title":"Cell Rep. Med."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0085","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/s12951-025-03251-y","article-title":"Responsive nanoparticles synergize with curcumin to break the \u201creactive oxygen species-neuroinflammation\u201d vicious cycle, enhancing traumatic brain injury outcomes","volume":"23","author":"Fu","year":"2025","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.brainres.2026.150509_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2024.108609","article-title":"Mechanistic and therapeutic relationships of traumatic brain injury and \u03b3-amino-butyric acid (GABA)","volume":"256","author":"Witkin","year":"2024","journal-title":"Pharmacol. Ther."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0095","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1038\/s41467-025-56292-0","article-title":"The transcriptional response of cortical neurons to concussion reveals divergent fates after injury","volume":"16","author":"Alkaslasi","year":"2025","journal-title":"Nat. Commun."},{"issue":"7","key":"10.1016\/j.brainres.2026.150509_b0100","article-title":"Single-nucleus RNA sequencing reveals that decorin expression in the amygdala regulates perineuronal nets expression and fear conditioning response after traumatic brain injury","volume":"9","author":"Shi","year":"2022","journal-title":"Adv. Sci. (Weinh)."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0125","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s12974-025-03430-6","article-title":"Single cell RNA sequencing after moderate traumatic brain injury: effects of therapeutic hypothermia","volume":"22","author":"Kerr","year":"2025","journal-title":"J. Neuroinflammation"},{"issue":"12","key":"10.1016\/j.brainres.2026.150509_b0130","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s41592-019-0619-0","article-title":"Fast, sensitive and accurate integration of single-cell data with Harmony","volume":"16","author":"Korsunsky","year":"2019","journal-title":"Nat. Methods"},{"issue":"3","key":"10.1016\/j.brainres.2026.150509_b0145","doi-asserted-by":"crossref","first-page":"898","DOI":"10.7150\/jca.102045","article-title":"Single-cell analysis unveils cell subtypes of acral melanoma cells at the early and late differentiation stages","volume":"16","author":"Hou","year":"2025","journal-title":"J. Cancer"},{"key":"10.1016\/j.brainres.2026.150509_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.tranon.2025.102364","article-title":"The potential role of C4 MYH11+ fibroblasts and the MDK-SDC2 ligand-receptor pair in lung adenocarcinoma: implications for prognosis and therapeutic strategies","volume":"55","author":"Jia","year":"2025","journal-title":"Transl. Oncol."},{"issue":"2","key":"10.1016\/j.brainres.2026.150509_b0155","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2021-004206","article-title":"Single-cell transcriptomics reveals a low CD8+ T cell infiltrating state mediated by fibroblasts in recurrent renal cell carcinoma","volume":"10","author":"Peng","year":"2022","journal-title":"J. Immunother. Cancer"},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0160","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s43657-023-00133-x","article-title":"Investigating the immunogenic cell death-dependent subtypes and prognostic signature of triple-negative breast cancer","volume":"4","author":"Shi","year":"2024","journal-title":"Phenomics (Cham, Switzerland)."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0165","first-page":"131","article-title":"GseaVis: an R package for enhanced visualization of gene set enrichment analysis in biomedicine","volume":"1","author":"Zhang","year":"2025","journal-title":"Med Res."},{"issue":"3","key":"10.1016\/j.brainres.2026.150509_b0170","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1007\/s43657-022-00086-7","article-title":"RNA-sequencing reveals gene expression and pathway signatures in umbilical cord blood affected by birth delivery mode","volume":"3","author":"Liu","year":"2023","journal-title":"Phenomics (Cham, Switzerland)."},{"issue":"5","key":"10.1016\/j.brainres.2026.150509_b0175","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1007\/s43657-023-00132-y","article-title":"Cellular senescence-related long non-coding RNA signatures predict prognosis in juvenile osteosarcoma","volume":"4","author":"Zhao","year":"2024","journal-title":"Phenomics (Cham, Switzerland)."},{"key":"10.1016\/j.brainres.2026.150509_b0180","article-title":"Decoding multiple myeloma: single-cell insights into tumor heterogeneity, immune dynamics, and disease progression","volume":"16","author":"Zhao","year":"2025","journal-title":"Front. Immunol."},{"issue":"7","key":"10.1016\/j.brainres.2026.150509_b0185","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1093\/brain\/awaf015","article-title":"Spreading depolarization triggers pro- and anti-inflammatory signalling: a potential link to headache","volume":"148","author":"Kaya","year":"2025","journal-title":"Brain J. Neurol."},{"issue":"3","key":"10.1016\/j.brainres.2026.150509_b0190","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1038\/s43587-024-00792-z","article-title":"Modulating mTOR-dependent astrocyte substate transitions to alleviate neurodegeneration","volume":"5","author":"Zhang","year":"2025","journal-title":"Nat. Aging"},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0195","doi-asserted-by":"crossref","DOI":"10.15212\/CVIA.2023.0023","article-title":"Single-cell RNA sequencing maps immune cell heterogeneity in mice with allogeneic cardiac transplantation","volume":"8","author":"Tong","year":"2023","journal-title":"CVIA"},{"issue":"8","key":"10.1016\/j.brainres.2026.150509_b0200","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2022-004807","article-title":"Single-cell transcriptomics reveals shared immunosuppressive landscapes of mouse and human neuroblastoma","volume":"10","author":"Costa","year":"2022","journal-title":"J. Immunother. Cancer"},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0205","doi-asserted-by":"crossref","first-page":"e1552","DOI":"10.1002\/ctm2.1552","article-title":"Deciphering the suppressive immune microenvironment of prostate cancer based on CD4+ regulatory T cells: implications for prognosis and therapy prediction","volume":"14","author":"Ge","year":"2024","journal-title":"Clin. Transl. Med."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0210","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/s41467-021-21246-9","article-title":"Inference and analysis of cell-cell communication using CellChat","volume":"12","author":"Jin","year":"2021","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.brainres.2026.150509_b0235","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/all.15510","article-title":"Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis","volume":"78","author":"Avlas","year":"2022","journal-title":"Allergy"},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0240","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/bjd.16905","article-title":"Expression profile of the amino acid transporters SLC7A5, SLC7A7, SLC7A8 and the enzyme TDO2 in basal cell carcinoma","volume":"180","author":"Tina","year":"2018","journal-title":"Br. J. Dermatol."},{"issue":"7","key":"10.1016\/j.brainres.2026.150509_b0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2019.11.016","article-title":"Metabolic control of astrocyte pathogenic activity via cPLA2-MAVS","volume":"179","author":"Chao","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.brainres.2026.150509_b0250","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1310094","article-title":"The role of midkine in health and disease","volume":"14","author":"Neumaier","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.brainres.2026.150509_b0255","article-title":"Ferroptosis-mediated hippocampal neuronal loss post-mTBI: chromatin accessibility profiling and single-nucleus transcriptomics","author":"Li","year":"2025","journal-title":"Adv. Sci. (Weinh)"},{"issue":"13","key":"10.1016\/j.brainres.2026.150509_b0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2021.05.001","article-title":"NDNF interneurons in layer 1 gain-modulate whole cortical columns according to an animal's behavioral state","volume":"109","author":"Cohen-Kashi Malina","year":"2021","journal-title":"Neuron"},{"key":"10.1016\/j.brainres.2026.150509_b0265","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.molmet.2019.06.001","article-title":"Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons","volume":"26","author":"Roberts","year":"2019","journal-title":"Mol. Metab."},{"issue":"2","key":"10.1016\/j.brainres.2026.150509_b0270","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.neuron.2016.09.026","article-title":"The calcium channel subunit Alpha2delta2 suppresses axon regeneration in the adult CNS","volume":"92","author":"Tedeschi","year":"2016","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0275","doi-asserted-by":"crossref","first-page":"9380","DOI":"10.1038\/s41467-025-64436-5","article-title":"Structural mechanisms of assembly, gating, and calmodulin modulation of human olfactory CNG channel","volume":"16","author":"Xue","year":"2025","journal-title":"Nat. Commun."},{"issue":"18","key":"10.1016\/j.brainres.2026.150509_b0280","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1016\/j.cub.2015.07.050","article-title":"Elevated mitochondrial bioenergetics and axonal arborization size are key contributors to the vulnerability of dopamine neurons","volume":"25","author":"Pacelli","year":"2015","journal-title":"Curr. Biol."},{"issue":"3","key":"10.1016\/j.brainres.2026.150509_b0285","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/s41593-020-00783-4","article-title":"Reactive astrocyte nomenclature, definitions, and future directions","volume":"24","author":"Escartin","year":"2021","journal-title":"Nat. Neurosci."},{"issue":"3","key":"10.1016\/j.brainres.2026.150509_b0290","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/s42255-023-00756-4","article-title":"Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration","volume":"5","author":"Mi","year":"2023","journal-title":"Nat. Metab."},{"issue":"5","key":"10.1016\/j.brainres.2026.150509_b0295","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/s41593-022-01049-x","article-title":"Neuronal activity drives pathway-specific depolarization of peripheral astrocyte processes","volume":"25","author":"Armbruster","year":"2022","journal-title":"Nat. Neurosci."},{"issue":"Pt 2","key":"10.1016\/j.brainres.2026.150509_b0300","article-title":"Role of bFGF on astrocytes to expression of protein molecules of blood-brain barrier via PI3K\/mTOR signaling pathway after TBI","volume":"307","author":"Long","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0305","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/s41420-023-01395-0","article-title":"Emerging roles of TFE3 in metabolic regulation","volume":"9","author":"Li","year":"2023","journal-title":"Cell Death Discov."},{"issue":"2","key":"10.1016\/j.brainres.2026.150509_b0310","article-title":"TFE3-mediated neuroprotection: clearance of aggregated \u03b1-synuclein and accumulated mitochondria in the AAV-\u03b1-synuclein model of Parkinson's disease","volume":"12","author":"He","year":"2024","journal-title":"Genes Dis."},{"issue":"3","key":"10.1016\/j.brainres.2026.150509_b0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.immuni.2021.01.004","article-title":"Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M","volume":"54","author":"Deerhake","year":"2021","journal-title":"Immunity"},{"issue":"8","key":"10.1016\/j.brainres.2026.150509_b0320","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1002\/glia.24377","article-title":"Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke","volume":"71","author":"Hernandez","year":"2023","journal-title":"Glia"},{"issue":"7999","key":"10.1016\/j.brainres.2026.150509_b0325","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/s41586-023-06935-3","article-title":"A molecular switch for neuroprotective astrocyte reactivity","volume":"626","author":"Cameron","year":"2023","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.brainres.2026.150509_b0352","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1038\/s41596-020-0336-2","article-title":"A scalable SCENIC workflow for single-cell gene regulatory network analysis","volume":"15","author":"Van de Sande","year":"2020","journal-title":"Nat Protoc"},{"key":"10.1016\/j.brainres.2026.150509_b0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.100513","article-title":"Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation","volume":"296","author":"Vester","year":"2021","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.brainres.2026.150509_b0335","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s00018-022-04300-7","article-title":"Nucleolin: a cell portal for viruses, bacteria, and toxins","volume":"79","author":"Tonello","year":"2022","journal-title":"Cell. Mol. Life Sci."},{"issue":"8011","key":"10.1016\/j.brainres.2026.150509_b0340","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/s41586-024-07317-z","article-title":"Control of neuronal excitation-inhibition balance by BMP-SMAD1 signalling","volume":"629","author":"Okur","year":"2024","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0345","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1038\/s42003-025-09138-w","article-title":"Astrocyte activation persists one year after TBI: a dynamic shift from inflammation to neurodegeneration","volume":"8","author":"Abou-El-Hassan","year":"2025","journal-title":"Commun. Biol."},{"issue":"1","key":"10.1016\/j.brainres.2026.150509_b0350","doi-asserted-by":"crossref","first-page":"5222","DOI":"10.1038\/s41467-024-49299-6","article-title":"Traumatic brain injury promotes neurogenesis at the cost of astrogliogenesis in the adult hippocampus of male mice","volume":"15","author":"Bielefeld","year":"2024","journal-title":"Nat. Commun."},{"issue":"11","key":"10.1016\/j.brainres.2026.150509_b0351","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1038\/nmeth.4463","article-title":"SCENIC: single-cell regulatory network inference and clustering","volume":"14","author":"Aibar","year":"2017","journal-title":"Nat Methods"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899326003719?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006899326003719?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:20:36Z","timestamp":1791418836000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006899326003719"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":61,"alternative-id":["S0006899326003719"],"URL":"https:\/\/doi.org\/10.1016\/j.brainres.2026.150509","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Single-cell reanalysis characterizes an Osmr+ astrocyte state and predicts midkine signaling to Cox6b1+ glutamatergic neurons at 24\u00a0h after traumatic brain injury","name":"articletitle","label":"Article Title"},{"value":"Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainres.2026.150509","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"150509"}}