{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:41:10Z","timestamp":1790790070959,"version":"4.1.0"},"reference-count":54,"publisher":"Elsevier BV","issue":"4-5","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research Bulletin"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1016\/j.brainresbull.2009.09.008","type":"journal-article","created":{"date-parts":[[2009,9,21]],"date-time":"2009-09-21T04:09:32Z","timestamp":1253506172000},"page":"491-496","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":84,"title":["Effects of \u03b2-carboline harmine on behavioral and physiological parameters observed in the chronic mild stress model: Further evidence of antidepressant properties"],"prefix":"10.1016","volume":"81","author":[{"given":"Juc\u00e9lia J.","family":"Fortunato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gislaine Z.","family":"R\u00e9us","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamires R.","family":"Kirsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto B.","family":"Stringari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel R.","family":"Fries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1vio","family":"Kapczinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime E.","family":"Hallak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ant\u00f4nio W.","family":"Zuardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 A.","family":"Crippa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Quevedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainresbull.2009.09.008_bib1","first-page":"1001","article-title":"Expression of brain-derived neurotrophic factor is not modulated by chronic mild stress in the rat hippocampus and amygdale","volume":"60","author":"Allaman","year":"2008","journal-title":"Pharmacol. Report."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/s11418-008-0259-7","article-title":"Alkaloids from the seeds of Peganum harmala showing antiplasmodial and vasorelaxant activities","volume":"62","author":"Astulla","year":"2008","journal-title":"Nat. Med."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.bbr.2005.01.005","article-title":"Behavioural and neurochemical effects induced by chronic mild stress applied to two different rat strains","volume":"161","author":"Bekris","year":"2005","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib4","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1126\/science.1120972","article-title":"Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress","volume":"311","author":"Berton","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib5","first-page":"295","article-title":"Childhood and adolescent depression: why do children and adults respond differently to antidepressant drugs?","volume":"23","author":"Bylund","year":"2009","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib6","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.biopsych.2006.02.013","article-title":"A neurotrophic model for stress-related mood disorders","volume":"59","author":"Duman","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib7","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/j.biopsych.2003.08.003","article-title":"Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression","volume":"54","author":"Eisch","year":"2003","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib8","article-title":"Antidepressant-like effect of harmane and other \u03b2-carbolines in the mouse forced swim test","volume":"324","author":"Farzin","year":"2006","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib9","doi-asserted-by":"crossref","unstructured":"J.J Fortunato, G.Z. R\u00e9us, T.M. Kirsch, R.B. Stringari, L. Stertz, F. Kapczinski, J.P. Pinto, J.E. Hallak, A.W. Zuardi, J.A. Crippa, J. Quevedo. Acute harmine administration induces antidepressant-like effects and increases BDNF levels in the rat hippocampus, Prog. Neuropsychopharmacol. Biol. Psychiatry (in press) doi:10.1016\/j.pnpbp.2009.07.021.","DOI":"10.1016\/j.pnpbp.2009.07.021"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib10","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.lfs.2006.01.002","article-title":"Effects of mood stabilizers on hippocampus BDNF levels in an animal model of mania","volume":"79","author":"Frey","year":"2006","journal-title":"Life Sci."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib11","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0197-0186(02)00080-3","article-title":"Effects stress on feeding behavior and on monoamine levels in structures","volume":"42","author":"Gamaro","year":"2003","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib12","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.pnpbp.2007.07.027","article-title":"Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus","volume":"32","author":"Garcia","year":"2008","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib13","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/j.1742-7843.2008.00210.x","article-title":"Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels","volume":"103","author":"Garcia","year":"2008","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib14","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.pnpbp.2009.01.004","article-title":"Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats","volume":"30","author":"Garcia","year":"2009","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib15","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0376-8716(99)00148-9","article-title":"Binding of beta-carbolines and related agents at serotonin (5-HT(2) and 5-HT(1A)), dopamine (D(2)) and benzodiazepine receptors","volume":"60","author":"Glennon","year":"2000","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib16","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.pbb.2006.11.021","article-title":"Chronic mild stress inhibits BDNF protein expression and CREB activation in the dentate gyrus but not in the in the hippocampus proper","volume":"85","author":"Gronli","year":"2006","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib17","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1038\/sj.mp.4002075","article-title":"Is it time to reassess the BDNF hypothesis of depression?","volume":"12","author":"Groves","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib18","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1080\/152873901753246241","article-title":"Toxicokinetics of tremorogenic natural products, harmane and harmine, in male Sprague\u2013Dawley rats","volume":"4","author":"Guan","year":"2001","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib19","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00213-008-1247-z","article-title":"Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors","volume":"201","author":"Halberstat","year":"2008","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib20","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0006-8993(01)02256-9","article-title":"Chronic variable stress and partial 5-HT denervation by parachloroamphetamine treatment in the rat: effects on behavior and monoamine neurochemistry","volume":"899","author":"Harro","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib21","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0376-8716(01)00123-5","article-title":"Betacarboline binding to imidazoline receptors","volume":"64","author":"Husbands","year":"2001","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib22","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.vph.2008.11.008","article-title":"Antiplatelet activity of \u03b2-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLC\u03b32 phosphorylation","volume":"50","author":"Im","year":"2009","journal-title":"Vascul. Pharmacol."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib23","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0165-1781(02)00005-7","article-title":"Decreased serum brain-derived neurotrophic factor levels in major depressed patients","volume":"15","author":"Karege","year":"2002","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib24","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0149-7634(81)90004-X","article-title":"Animal models and human depressive disorders","volume":"5","author":"Katz","year":"1981","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib25","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1046\/j.0953-816x.2001.01563.x","article-title":"Protective effect of harmaline and harmalol against dopamine- and 6-hydroxydopamine-induced oxidative damage of brain mitochondria and synaptosomes, and viability loss of PC12 cells","volume":"13","author":"Kim","year":"2001","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib26","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1006\/abbi.1996.9771","article-title":"Inhibition of monoamine oxidase A by beta-carboline derivatives","volume":"337","author":"Kim","year":"1997","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib27","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.neuint.2007.04.006","article-title":"Theory of active antidepressants: a nonsynaptic approach to the treatment of depression","volume":"52","author":"Kiss","year":"2008","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib28","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0163-1047(90)90458-I","article-title":"Predictability of chronic intermittent stress: effects on sympathetic-adrenal medullary responses of laboratory rats","volume":"53","author":"Konarska","year":"1990","journal-title":"Behav. Neural Biol."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib29","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.pharmthera.2007.07.001","article-title":"Brain-derived neurotrophic factor and its receptor tropomyosin-related kinase B in the mechanism of action of antidepressant therapies","volume":"117","author":"Kozisek","year":"2008","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib30","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.cell.2007.09.018","article-title":"Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions","volume":"131","author":"Krishnan","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib31","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1038\/nature07455","article-title":"The molecular neurobiology of depression","volume":"455","author":"Krishnan","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib32","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib33","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2174\/156720208786413406","article-title":"Chronic mild stress paradigm reduces sweet food intake in rats without affecting brain derived neurotrophic factor protein levels","volume":"5","author":"Lucca","year":"2008","journal-title":"Curr. Neurovasc. Res."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib34","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.jpsychires.2008.11.002","article-title":"Increased oxidative stress in submitochondrial particles into the brain of rats submitted to the chronic mild stress paradigm","volume":"43","author":"Lucca","year":"2009","journal-title":"J. Psychiatry Res."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib35","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.neuint.2009.01.001","article-title":"Effects of chronic mild stress on the oxidative parameters in the rat brain","volume":"54","author":"Lucca","year":"2009","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib36","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/nn1971","article-title":"New insights into BDNF function in depression and anxiety","volume":"10","author":"Martinowich","year":"2007","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib37","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.neuint.2009.04.005","article-title":"Inhibitory effect of antidepressants on the NMDA-evoked [3H] noradrenaline release from rat hippocampal slices","volume":"55","author":"Mayer","year":"2009","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib38","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.biopsych.2006.03.021","article-title":"Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors","volume":"61","author":"Monteggia","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib39","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/mutage\/gem016","article-title":"Antioxidant properties of \u03b2-carboline alkaloids are related to their antimutagenic and antigenotoxic activities","volume":"22","author":"Moura","year":"2007","journal-title":"Mutagenesis"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib40","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0896-6273(02)00653-0","article-title":"Neurobiology of depression","volume":"34","author":"Nestler","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib41","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1093\/qjmed\/93.6.323","article-title":"The stress response and the hypothalamic\u2013pituitary\u2013adrenal axis: from molecule to melancholia","volume":"93","author":"O\u2019Connor","year":"2000","journal-title":"Q. J. Med."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.psc.2006.12.005","article-title":"The molecular neurobiology of depression","volume":"30","author":"Richard","year":"2007","journal-title":"Psychiatry Clin. North Am."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib43","doi-asserted-by":"crossref","first-page":"6268","DOI":"10.1111\/j.1742-4658.2008.06751.x","article-title":"DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine","volume":"275","author":"Seifert","year":"2008","journal-title":"FEBS J."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib44","doi-asserted-by":"crossref","first-page":"3251","DOI":"10.1523\/JNEUROSCI.22-08-03251.2002","article-title":"Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression","volume":"22","author":"Shirayama","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib45","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.neuroscience.2008.09.034","article-title":"The Down Syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1a phosphorylates the neurodegeneration-related septin 4","volume":"157","author":"Sitz","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib46","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0091-3057(96)00169-4","article-title":"Antidepressant-like effect of brain-derived neurotrophic factor (BDNF)","volume":"56","author":"Siuciak","year":"1997","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib47","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.bbrc.2004.03.019","article-title":"Specific inhibition of cyclin-dependent kinases and cell proliferation by harmine","volume":"317","author":"Song","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib48","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1139\/y99-049","article-title":"\u201cRational hope\u201d in the early treatment of Parkinson's disease","volume":"77","author":"Sourkes","year":"1999","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib49","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.neuint.2009.06.013","article-title":"BDNF downregulates 5-HT2A receptor protein levels in hippocampal cultures","volume":"55","author":"Trajkovska","year":"2009","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib50","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S1566-2772(03)00086-0","article-title":"Stress models of depression","volume":"3","author":"Vollmayr","year":"2003","journal-title":"Clin. Neurosci. Res."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib51","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.cmet.2007.03.010","article-title":"The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARg expression","volume":"5","author":"Waki","year":"2007","journal-title":"Cell Metab."},{"key":"10.1016\/j.brainresbull.2009.09.008_bib52","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1007\/BF00187257","article-title":"Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant","volume":"93","author":"Willner","year":"1987","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib53","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1159\/000087097","article-title":"Chronic mild stress (CMS) revisited: consistency and behavioral neurobiological concordance in the effects of CMS","volume":"52","author":"Wilner","year":"2005","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.brainresbull.2009.09.008_bib54","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/S0006-3223(03)00418-9","article-title":"Gass PForebrain-specific trkB-receptor knockout mice: behaviorally more hyperactive than \u2018depressive\u2019","volume":"54","author":"Z\u00f6rner","year":"2003","journal-title":"Biol. Psychiatry"}],"container-title":["Brain Research Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0361923009003049?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0361923009003049?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T20:08:28Z","timestamp":1759781308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0361923009003049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":54,"journal-issue":{"issue":"4-5","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S0361923009003049"],"URL":"https:\/\/doi.org\/10.1016\/j.brainresbull.2009.09.008","relation":{},"ISSN":["0361-9230"],"issn-type":[{"value":"0361-9230","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of \u03b2-carboline harmine on behavioral and physiological parameters observed in the chronic mild stress model: Further evidence of antidepressant properties","name":"articletitle","label":"Article Title"},{"value":"Brain Research Bulletin","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainresbull.2009.09.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}