{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:17:29Z","timestamp":1761765449634,"version":"build-2065373602"},"reference-count":26,"publisher":"Elsevier BV","issue":"5-6","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Department of Veterans Affairs Career Development Award","award":["200600158"],"award-info":[{"award-number":["200600158"]}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["R01-DK-069988"],"award-info":[{"award-number":["R01-DK-069988"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research Bulletin"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.brainresbull.2011.09.001","type":"journal-article","created":{"date-parts":[[2011,9,10]],"date-time":"2011-09-10T04:50:00Z","timestamp":1315630200000},"page":"380-384","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Lumbosacral sensory neuronal activity is enhanced by activation of urothelial purinergic receptors"],"prefix":"10.1016","volume":"86","author":[{"given":"Alvaro","family":"Munoz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George T.","family":"Somogyi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy B.","family":"Boone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher P.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainresbull.2011.09.001_bib0005","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/nau.20940","article-title":"Effects of intravesical instillation of ATP on rat bladder primary afferent activity and its relationship with capsaicin-sensitivity","volume":"30","author":"Aizawa","year":"2011","journal-title":"Neurourol. Urodyn."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0010","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/ncpuro0672","article-title":"Mechanisms of disease: involvement of the urothelium in bladder dysfunction","volume":"4","author":"Birder","year":"2007","journal-title":"Nat. Clin. Pract. Urol."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0015","doi-asserted-by":"crossref","first-page":"F1084","DOI":"10.1152\/ajprenal.00118.2004","article-title":"Alterations in P2X and P2Y purinergic receptor expression in urinary bladder from normal cats and cats with interstitial cystitis","volume":"287","author":"Birder","year":"2004","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0020","doi-asserted-by":"crossref","first-page":"F821","DOI":"10.1152\/ajprenal.00321.2006","article-title":"Expression and function of rat urothelial P2Y receptors","volume":"294","author":"Chopra","year":"2008","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0025","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1113\/jphysiol.2005.088435","article-title":"P2X2 knockout mice and P2X2\/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP","volume":"567","author":"Cockayne","year":"2005","journal-title":"J. Physiol."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0030","doi-asserted-by":"crossref","first-page":"3973","DOI":"10.1523\/JNEUROSCI.5239-04.2005","article-title":"Differential responses of bladder lumbosacral and thoracolumbar dorsal root ganglion neurons to purinergic agonists, protons, and capsaicin","volume":"25","author":"Dang","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0035","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/978-3-540-79090-7_4","article-title":"Afferent nerve regulation of bladder function in health and disease","author":"de Groat","year":"2009","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0040","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/978-3-642-16499-6_22","article-title":"ATP and P2X purinoceptors in urinary tract disorders","author":"Ford","year":"2011","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0045","doi-asserted-by":"crossref","first-page":"4503","DOI":"10.1523\/JNEUROSCI.6132-09.2010","article-title":"Endogenous purinergic control of bladder activity via presynaptic P2X3 and P2X2\/3 receptors in the spinal cord","volume":"30","author":"Kaan","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0050","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.neuint.2004.06.001","article-title":"Botulinum toxin A inhibits ATP release from bladder urothelium after chronic spinal cord injury","volume":"45","author":"Khera","year":"2004","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0055","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.urology.2005.01.055","article-title":"In vivo effects of botulinum toxin A on visceral sensory function in chronic spinal cord-injured rats","volume":"66","author":"Khera","year":"2005","journal-title":"Urology"},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0060","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.neuint.2010.12.002","article-title":"Overactive and underactive bladder dysfunction is reflected by alterations in urothelial ATP and NO release","volume":"58","author":"Munoz","year":"2011","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0065","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0006-8993(01)03216-4","article-title":"Evidence for two populations of rat spinal dorsal horn neurons excited by urinary bladder distension","volume":"923","author":"Ness","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0070","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.urology.2005.06.099","article-title":"Detrusor overactivity induced by intravesical application of adenosine 5\u2032-triphosphate under different delivery conditions in rats","volume":"66","author":"Nishiguchi","year":"2005","journal-title":"Urology"},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0075","first-page":"0","article-title":"Intravesical adenosine triphosphate stimulates the micturition reflex in awake, freely moving rats, in:","volume":"123","author":"Pandita","year":"2002","journal-title":"J. Urol. (United States)"},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0080","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.neuint.2006.09.002","article-title":"Receptor activated bladder and spinal ATP release in neurally intact and chronic spinal cord injured rats","volume":"50","author":"Salas","year":"2007","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0085","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.neuint.2007.11.006","article-title":"Botulinum toxin type A normalizes alterations in urothelial ATP and NO release induced by chronic spinal cord injury","volume":"52","author":"Smith","year":"2008","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0090","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.neuint.2005.04.021","article-title":"Enhanced ATP release from rat bladder urothelium during chronic bladder inflammation: effect of botulinum toxin A","volume":"47","author":"Smith","year":"2005","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0095","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.2174\/156802611795347564","article-title":"The role of extracellular adenosine in chemical neurotransmission in the hippocampus and Basal Ganglia: pharmacological and clinical aspects","volume":"11","author":"Sperlagh","year":"2011","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0100","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/01.ju.0000143189.19835.f3","article-title":"Inhibitory effect of intravesically applied botulinum toxin A in chronic bladder inflammation","volume":"173","author":"Vemulakonda","year":"2005","journal-title":"J. Urol."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0105","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1172\/JCI24086","article-title":"ATP and purinergic receptor-dependent membrane traffic in bladder umbrella cells","volume":"115","author":"Wang","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0110","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s00210-007-0209-z","article-title":"Therapeutic receptor targets for lower urinary tract dysfunction","volume":"377","author":"Yoshimura","year":"2008","journal-title":"N.-S. Arch Pharmacol"},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0115","doi-asserted-by":"crossref","first-page":"e18704","DOI":"10.1371\/journal.pone.0018704","article-title":"Expression and distribution of ectonucleotidases in mouse urinary bladder","volume":"6","author":"Yu","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0120","doi-asserted-by":"crossref","first-page":"C254","DOI":"10.1152\/ajpcell.00025.2006","article-title":"Adenosine receptor expression and function in bladder uroepithelium","volume":"291","author":"Yu","year":"2006","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0125","doi-asserted-by":"crossref","first-page":"F1146","DOI":"10.1152\/ajprenal.00592.2007","article-title":"Sensitization of pelvic afferent nerves in the in vitro rat urinary bladder-pelvic nerve preparation by purinergic agonists and cyclophosphamide pretreatment","volume":"294","author":"Yu","year":"2008","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.brainresbull.2011.09.001_bib0130","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.brainres.2010.09.018","article-title":"Effects of stimulation of muscarinic receptors on bladder afferent nerves in the in vitro bladder-pelvic afferent nerve preparation of the rat","volume":"1361","author":"Yu","year":"2010","journal-title":"Brain Res."}],"container-title":["Brain Research Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S036192301100267X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S036192301100267X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T20:13:12Z","timestamp":1759781592000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S036192301100267X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":26,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S036192301100267X"],"URL":"https:\/\/doi.org\/10.1016\/j.brainresbull.2011.09.001","relation":{},"ISSN":["0361-9230"],"issn-type":[{"type":"print","value":"0361-9230"}],"subject":[],"published":{"date-parts":[[2011,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lumbosacral sensory neuronal activity is enhanced by activation of urothelial purinergic receptors","name":"articletitle","label":"Article Title"},{"value":"Brain Research Bulletin","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainresbull.2011.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}