{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:21:11Z","timestamp":1791264071192,"version":"4.1.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"NKTH-OTKA","award":["K 68431"],"award-info":[{"award-number":["K 68431"]}]},{"name":"SROP","award":["4.2.2\/B-10\/1-2010-0029"],"award-info":[{"award-number":["4.2.2\/B-10\/1-2010-0029"]}]},{"name":"SROP","award":["4.2.1\/B-10\/2\/KONV-2010-0002"],"award-info":[{"award-number":["4.2.1\/B-10\/2\/KONV-2010-0002"]}]},{"DOI":"10.13039\/501100003825","name":"Hungarian Academy of Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003825","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research Bulletin"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1016\/j.brainresbull.2012.06.001","type":"journal-article","created":{"date-parts":[[2012,6,10]],"date-time":"2012-06-10T06:32:30Z","timestamp":1339309950000},"page":"589-595","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Microinjection of RFRP-1 in the central nucleus of amygdala decreases food intake in the rat"],"prefix":"10.1016","volume":"88","author":[{"given":"Anita","family":"Kov\u00e1cs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krist\u00f3f","family":"L\u00e1szl\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"G\u00e1losi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kriszti\u00e1n","family":"T\u00f3th","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"Ollmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e1szl\u00f3","family":"P\u00e9czely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e1szl\u00f3","family":"L\u00e9n\u00e1rd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainresbull.2012.06.001_bib0005","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1677\/JOE-06-0069","article-title":"The role of RFamide peptides in feeding","volume":"192","author":"Bechtold","year":"2007","journal-title":"Journal of Endocrinology"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0010","doi-asserted-by":"crossref","first-page":"4723","DOI":"10.1210\/en.2006-0753","article-title":"Prolactin-releasing peptide mediates CCK-induced satiety in mice","volume":"147","author":"Bechtold","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0015","doi-asserted-by":"crossref","first-page":"39324","DOI":"10.1074\/jbc.M004385200","article-title":"Identification and characterization of two G protein-coupled receptors for neuropeptide FF","volume":"275","author":"Bonini","year":"2000","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0020","doi-asserted-by":"crossref","first-page":"15247","DOI":"10.1073\/pnas.2434676100","article-title":"Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity","volume":"100","author":"Chartrel","year":"2003","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0025","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/0271-5317(95)00024-0","article-title":"Food intake after amygdaloid lesions in the rats","volume":"15","author":"Crovetti","year":"1995","journal-title":"Nutrition Research"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0030","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1113\/expphysiol.2004.027169","article-title":"The expanding family of -Rfamide peptides and their effects on feeding behavior","volume":"89","author":"Dockray","year":"2004","journal-title":"Experimental Physiology"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0035","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1124\/jpet.102.047118","article-title":"Prolactin releasing peptide has high affinity and efficacy at neuropeptide FF2 receptors","volume":"305","author":"Engstrom","year":"2003","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0040","first-page":"28","article-title":"PrRP inhibits food intake in rats after central nucleus of amygdala microinjection","volume":"1","author":"Fan","year":"2005","journal-title":"Henan Medical Research"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0045","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0006-8993(02)03362-0","article-title":"Gastrin-releasing peptide microinjected into the amygdala inhibits feeding","volume":"955","author":"Fekete","year":"2002","journal-title":"Brain Research"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0050","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.brainresbull.2006.10.007","article-title":"Neuromedin C microinjected into the amygdala inhibits feeding","volume":"71","author":"Fekete","year":"2007","journal-title":"Brain Research Bulletin"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0055","first-page":"719","article-title":"Aphagia, produced by destruction of the dorsomedial amygdala in dogs","volume":"14","author":"Fonberg","year":"1966","journal-title":"Bulletin de l\u2019Academie Polonaise des Sciences. Serie des Sciences Biologiques"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0060","first-page":"19","article-title":"Hyperphagia produced by lateral amygdalar lesions in dogs","volume":"31","author":"Fonberg","year":"1971","journal-title":"Acta Neurobiologiae Experimentalis (Wars)"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0065","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.peptides.2005.06.031","article-title":"Recent advances in mammalian RFamide peptides: the discovery and functional analyses of PrRP, RFRPs and QRFP","volume":"27","author":"Fukusumi","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0070","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0167-4889(01)00135-5","article-title":"Characteristics and distribution of endogenous RFamide-related peptide-1","volume":"1540","author":"Fukusumi","year":"2001","journal-title":"Biochimica et Biophysica Acta"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0075","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/syn.10305","article-title":"Detailed distribution of neuropeptide FF receptors (NPFF1 and NPFF2) in the rat, mouse, octodon, rabbit, guinea pig, and marmoset monkey brains: a comparative autoradiographic study","volume":"51","author":"Gouarderes","year":"2004","journal-title":"Synapse"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0080","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/0361-9230(92)90165-T","article-title":"Feeding disturbances and EEG activity changes after amygdaloid kainate lesions in the rat","volume":"29","author":"Hajnal","year":"1992","journal-title":"Brain Research Bulletin"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0085","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ics.2006.02.034","article-title":"Orexin-A microinjection mediated food and water intake are antagonized by selective orexin-1 receptor antagonist in the bed nucleus of stria terminalis","volume":"1291","author":"Hangodi","year":"2006","journal-title":"International Congress Series"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0090","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.bbrc.2008.09.071","article-title":"RFamide neuropeptides inhibit murine and human adipose differentiation","volume":"377","author":"Herrera-Herrera","year":"2008","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0095","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/35036326","article-title":"New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals","volume":"2","author":"Hinuma","year":"2000","journal-title":"Nature Cell Biology"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0100","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/BF00239551","article-title":"Amygdaloid projections to the mesencephalon, pons and medulla oblongata in the cat","volume":"32","author":"Hopkins","year":"1978","journal-title":"Experimental Brain Research"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0105","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0149-7634(89)80027-2","article-title":"The relationship between reinforcement and memory \u2013 parallels in the rewarding and mnemonic effects of the neuropeptide substance-P","volume":"13","author":"Huston","year":"1989","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0110","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.peptides.2005.09.017","article-title":"Facilitation of spinal morphine analgesia in normal and morphine tolerant animals by neuropeptide SF and related peptides","volume":"27","author":"Jhamandas","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0115","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1365-2826.2010.02077.x","article-title":"Effects of RFamide-related peptide (RFRP)-1 and RFRP-3 on oxytocin release and anxiety-related behaviour in rats","volume":"23","author":"Kaewwongse","year":"2011","journal-title":"Journal of Neuroendocrinology"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0120","doi-asserted-by":"crossref","first-page":"11324","DOI":"10.1073\/pnas.0901176106","article-title":"Stress increases putative gonadotropin inhibitory hormone and decreases luteinizing hormone in male rats","volume":"106","author":"Kirby","year":"2009","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0125","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1210\/endo.143.2.8609","article-title":"PRL-releasing peptide reduces food intake and may mediate satiety signaling","volume":"143","author":"Lawrence","year":"2002","journal-title":"Endocrinology"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0130","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0006-8993(82)90934-9","article-title":"Amygdalar noradrenergic and dopaminergic mechanisms in the regulation of hunger and thirst-motivated behavior","volume":"233","author":"Lenard","year":"1982","journal-title":"Brain Research"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0135","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0006-8993(82)90173-1","article-title":"Body weight changes after neurochemical manipulations of lateral amygdala: noradrenergic and dopaminergic mechanisms","volume":"249","author":"Lenard","year":"1982","journal-title":"Brain Research"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0140","doi-asserted-by":"crossref","first-page":"36961","DOI":"10.1074\/jbc.M105308200","article-title":"Identification and characterization of novel mammalian neuropeptide FF-like peptides that attenuate morphine-induced antinociception","volume":"276","author":"Liu","year":"2001","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0145","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1677\/JOE-08-0197","article-title":"Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats","volume":"199","author":"Murakami","year":"2008","journal-title":"Journal of Endocrinology"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0150","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0196-9781(95)02137-X","article-title":"Neuropeptide FF reduces food intake in rats","volume":"17","author":"Murase","year":"1996","journal-title":"Peptides"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0155","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.bbr.2009.06.013","article-title":"Neuropeptide SF is associated with reduced food intake in chicks","volume":"205","author":"Newmyer","year":"2009","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0160","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1038\/2281108a0","article-title":"Inhibitory action of the amygdala on the lateral hypothalamic area in rats","volume":"228","author":"Oomura","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0165","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1111\/j.1742-4658.2006.05187.x","article-title":"Evolutionary origin and divergence of PQRFamide peptides and LPXRFamide peptides in the RFamide peptide family. Insights from novel lamprey RFamide peptides","volume":"273","author":"Osugi","year":"2006","journal-title":"FEBS Journal"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0170","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"1986"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0175","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.neuroscience.2005.04.050","article-title":"RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat","volume":"134","author":"Pertovaara","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0180","doi-asserted-by":"crossref","first-page":"E39","DOI":"10.1152\/ajpendo.00108.2010","article-title":"Characterization of the inhibitory roles of RFRP3, the mammalian ortholog of GnIH, in the control of gonadotropin secretion in the rat: in vivo and in vitro studies","volume":"299","author":"Pineda","year":"2010","journal-title":"American Journal of Physiology, Endocrinology and Metabolism"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0185","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1210\/en.2009-1259","article-title":"Characterization of the potent gonadotropin-releasing activity of RF9, a selective antagonist of RFamide-related peptides and neuropeptide FF receptors: physiological and pharmacological implications","volume":"151","author":"Pineda","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0190","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1111\/j.1365-2826.2009.01886.x","article-title":"Projections of RFamide-related peptide-3 neurones in the ovine hypothalamus, with special reference to regions regulating energy balance and reproduction","volume":"21","author":"Qi","year":"2009","journal-title":"Journal of Neuroendocrinology"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0195","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1073\/pnas.0502090103","article-title":"RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance and paradoxical hyperalgesia","volume":"103","author":"Simonin","year":"2006","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0200","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.tem.2009.11.010","article-title":"Gonadotropin inhibitory hormone function in mammals","volume":"21","author":"Smith","year":"2010","journal-title":"Trends in Endocrinology and Metabolism"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0205","doi-asserted-by":"crossref","first-page":"7438","DOI":"10.1073\/pnas.0602371103","article-title":"A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice","volume":"103","author":"Takayasu","year":"2006","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0210","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/mas.20031","article-title":"A new member of the hypothalamic RF-amide peptide family, LPXRF-amide peptides: structure, localization, and function","volume":"24","author":"Ukena","year":"2005","journal-title":"Mass Spectrometry Reviews"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0215","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1385\/ENDO:20:1-2:59","article-title":"Prolactin-releasing peptide and its homolog RFRP-1 act in hypothalamus but not in anterior pituitary gland to stimulate stress hormone secretion","volume":"20","author":"Willis","year":"2003","journal-title":"Endocrine"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0220","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.devbrainres.2004.06.008","article-title":"Developmental expression of RFamide-related peptides in the rat central nervous system","volume":"152","author":"Yano","year":"2004","journal-title":"Developmental Brain Research"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0225","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S0006-8993(03)02877-4","article-title":"Localization and neuronal response of RFamide related peptides in the rat central nervous system","volume":"982","author":"Yano","year":"2003","journal-title":"Brain Research"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0230","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0167-4889(02)00389-0","article-title":"Molecular properties of endogenous RFamide-related peptide-3 and its interaction with receptors","volume":"1593","author":"Yoshida","year":"2003","journal-title":"Biochimica et Biophysica Acta"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0235","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.neures.2006.04.011","article-title":"Peripherally applied neuropeptide SF is equally algogenic in wild type and ASIC3\u2013\/\u2013 mice","volume":"55","author":"Yudin","year":"2006","journal-title":"Neuroscience Research"},{"key":"10.1016\/j.brainresbull.2012.06.001_bib0240","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0891-0618(03)00038-3","article-title":"Neuropeptide FF receptor 2 (NPFF2) is localized to pain-processing regions in the primate spinal of the medulla cord and the lower level oblongata","volume":"25","author":"Zeng","year":"2003","journal-title":"Journal of Chemical Neuroanatomy"}],"container-title":["Brain Research Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S036192301200127X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S036192301200127X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T20:15:44Z","timestamp":1759781744000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S036192301200127X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S036192301200127X"],"URL":"https:\/\/doi.org\/10.1016\/j.brainresbull.2012.06.001","relation":{},"ISSN":["0361-9230"],"issn-type":[{"value":"0361-9230","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microinjection of RFRP-1 in the central nucleus of amygdala decreases food intake in the rat","name":"articletitle","label":"Article Title"},{"value":"Brain Research Bulletin","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainresbull.2012.06.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}