{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T04:24:20Z","timestamp":1771647860579,"version":"3.50.1"},"reference-count":55,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research Bulletin"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1016\/j.brainresbull.2012.06.002","type":"journal-article","created":{"date-parts":[[2012,6,13]],"date-time":"2012-06-13T06:08:55Z","timestamp":1339567735000},"page":"581-588","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Anti-nociceptive effects of Tanshinone IIA (TIIA) in a rat model of complete Freund's adjuvant (CFA)-induced inflammatory pain"],"prefix":"10.1016","volume":"88","author":[{"given":"Shukai","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fale","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daoshu","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunqing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Longxing","family":"Ni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainresbull.2012.06.002_bib0005","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/ar.1090940210","article-title":"Estimation of nuclear population from microtome sections","volume":"94","author":"Abercrombie","year":"1946","journal-title":"Anatomical Record"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0010","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.pain.2004.06.009","article-title":"Inflammation persistently enhances nocifensive behaviors mediated by spinal group I mGluRs through sustained ERK activation","volume":"111","author":"Adwanikar","year":"2004","journal-title":"Pain"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0015","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s10620-007-9863-8","article-title":"Tanshinone IIA ameliorates trinitrobenzene sulfonic acid (TNBS)-induced murine colitis","volume":"53","author":"Bai","year":"2008","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0020","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1055\/s-2003-45141","article-title":"Anti-inflammatory compounds of plant origin. Part I. Action on arachidonic acid pathway, nitric oxide and nuclear factor kappa B (NF-kappaB)","volume":"69","author":"Calixto","year":"2003","journal-title":"Planta Medica"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0025","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1055\/s-2004-815483","article-title":"Anti-inflammatory compounds of plant origin. Part II. Modulation of pro-inflammatory cytokines, chemokines and adhesion molecules","volume":"70","author":"Calixto","year":"2004","journal-title":"Planta Medica"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0030","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0304-3940(01)02093-6","article-title":"Peripheral capsaicin receptors increase in the inflamed rat hindpaw: a possible mechanism for peripheral sensitization","volume":"310","author":"Carlton","year":"2001","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0035","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/39807","article-title":"The capsaicin receptor: a heat-activated ion channel in the pain pathway","volume":"389","author":"Caterina","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0040","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1126\/science.288.5464.306","article-title":"Impaired nociception and pain sensation in mice lacking the capsaicin receptor","volume":"288","author":"Caterina","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0045","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1007\/BF02975887","article-title":"Molecular mechanisms of inhibitory activities of tanshinones on lipopolysaccharide-induced nitric oxide generation in RAW 264.7 cells","volume":"27","author":"Choi","year":"2004","journal-title":"Archives of Pharmacal Research"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0050","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1111\/j.1432-1033.2004.04082.x","article-title":"Biochemical pharmacology of the vanilloid receptor TRPV1. An update","volume":"271","author":"Cortright","year":"2004","journal-title":"European Journal of Biochemistry"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0055","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/j.1476-5381.1992.tb14503.x","article-title":"The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia","volume":"107","author":"Cunha","year":"1992","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0060","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1073\/pnas.0409225102","article-title":"A cascade of cytokines mediates mechanical inflammatory hypernociception in mice","volume":"102","author":"Cunha","year":"2005","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0065","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/35012076","article-title":"Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia","volume":"405","author":"Davis","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0070","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1182\/blood.V87.6.2095.bloodjournal8762095","article-title":"Biologic basis for interleukin-1 in disease","volume":"87","author":"Dinarello","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0075","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1089\/cbr.2009.0640","article-title":"Anti-inflammatory effects of tanshinone IIA on radiation-induced microglia BV-2 cells inflammatory response","volume":"24","author":"Dong","year":"2009","journal-title":"Cancer Biotherapy and Radiopharmaceuticals"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0080","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.2174\/138161209788186263","article-title":"Acid sensing ion channels and acid nociception","volume":"15","author":"Dube","year":"2009","journal-title":"Current Pharmaceutical Design"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0085","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/334698a0","article-title":"Interleukin-1 beta as a potent hyperalgesic agent antagonized by a tripeptide analogue","volume":"334","author":"Ferreira","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0090","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0169-328X(03)00284-5","article-title":"Extracellular signaling-regulated kinase-1 and -2 (ERK 1\/2) mediate referred hyperalgesia in a murine model of visceral pain","volume":"116","author":"Galan","year":"2003","journal-title":"Brain Research. Molecular Brain Research"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cne.10221","article-title":"On counting and counting errors","volume":"447","author":"Guillery","year":"2002","journal-title":"Journal of Comparative Neurology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0100","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0304-3959(00)00353-5","article-title":"Cloning and functional expression of a human orthologue of rat vanilloid receptor-1","volume":"88","author":"Hayes","year":"2000","journal-title":"Pain"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0105","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.mcn.2007.07.010","article-title":"The cytokine TNFalpha increases the proportion of DRG neurones expressing the TRPV1 receptor via the TNFR1 receptor and ERK activation","volume":"36","author":"Hensellek","year":"2007","journal-title":"Molecular and Cellular Neurosciences"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0110","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2174\/157015906778019554","article-title":"Inflammatory pain: the cellular basis of heat hyperalgesia","volume":"4","author":"Huang","year":"2006","journal-title":"Current Neuropharmacology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0115","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0304-3959(89)90135-8","article-title":"Expansion of receptive fields of spinal lamina I projection neurons in rats with unilateral adjuvant-induced inflammation: the contribution of dorsal horn mechanisms","volume":"37","author":"Hylden","year":"1989","journal-title":"Pain"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0120","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0304-3959(88)90141-8","article-title":"Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding","volume":"35","author":"Iadarola","year":"1988","journal-title":"Pain"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0125","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1055\/s-2003-45157","article-title":"Tanshinone IIA from Salvia miltiorrhiza inhibits inducible nitric oxide synthase expression and production of TNF-alpha, IL-1beta and IL-6 in activated RAW 264.7 cells","volume":"69","author":"Jang","year":"2003","journal-title":"Planta Medica"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejphar.2006.04.044","article-title":"Tanshinone IIA inhibits LPS-induced NF-kappaB activation in RAW 264.7 cells: possible involvement of the NIK-IKK, ERK1\/2, p38 and JNK pathways","volume":"542","author":"Jang","year":"2006","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0135","first-page":"71","article-title":"Mitogen-activated protein kinases as potential targets for pain killers","volume":"5","author":"Ji","year":"2004","journal-title":"Current Opinion in Investigational Drugs"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/nbdi.2000.0360","article-title":"Neuronal plasticity and signal transduction in nociceptive neurons: implications for the initiation and maintenance of pathological pain","volume":"8","author":"Ji","year":"2001","journal-title":"Neurobiology of Disease"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0145","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0896-6273(02)00908-X","article-title":"p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia","volume":"36","author":"Ji","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0150","doi-asserted-by":"crossref","first-page":"4017","DOI":"10.1523\/JNEUROSCI.23-10-04017.2003","article-title":"p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain","volume":"23","author":"Jin","year":"2003","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0155","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1211\/jpp.59.5.0015","article-title":"Differential involvement of TRPV1 receptors at the central and peripheral nerves in CFA-induced mechanical and thermal hyperalgesia","volume":"59","author":"Kanai","year":"2007","journal-title":"Journal of Pharmacy and Pharmacology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0160","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0162-3109(00)00256-3","article-title":"Inhibition of interleukin-12 and interferon-gamma production in immune cells by tanshinones from Salvia miltiorrhiza","volume":"49","author":"Kang","year":"2000","journal-title":"Immunopharmacology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0165","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1744-8069-2-2","article-title":"Impaired inflammatory pain and thermal hyperalgesia in mice expressing neuron-specific dominant negative mitogen activated protein kinase kinase (MEK)","volume":"2","author":"Karim","year":"2006","journal-title":"Molecular Pain"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0170","doi-asserted-by":"crossref","first-page":"8310","DOI":"10.1523\/JNEUROSCI.2396-04.2004","article-title":"Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization","volume":"24","author":"Kawasaki","year":"2004","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0175","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/bja\/87.1.3","article-title":"Mechanisms of inflammatory pain","volume":"87","author":"Kidd","year":"2001","journal-title":"British Journal of Anaesthesia"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0180","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0074-7742(09)85014-9","article-title":"Involvement of inflammatory mediators in neuropathic pain caused by vincristine","volume":"85","author":"Kiguchi","year":"2009","journal-title":"International Review of Neurobiology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0185","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.bcp.2009.02.014","article-title":"Analgesic potential of TRPV1 antagonists","volume":"78","author":"Kym","year":"2009","journal-title":"Biochemical Pharmacology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0190","doi-asserted-by":"crossref","first-page":"3856","DOI":"10.4049\/jimmunol.178.6.3856","article-title":"A cardiovascular drug rescues mice from lethal sepsis by selectively attenuating a late-acting proinflammatory mediator, high mobility group box 1","volume":"178","author":"Li","year":"2007","journal-title":"Journal of Immunology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0195","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1097\/00001756-200403220-00016","article-title":"Change of vanilloid receptor 1 expression in dorsal root ganglion and spinal dorsal horn during inflammatory nociception induced by complete Freund's adjuvant in rats","volume":"15","author":"Luo","year":"2004","journal-title":"Neuroreport"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0200","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1038\/sj.bjp.0703918","article-title":"Pharmacological differences between the human and rat vanilloid receptor 1 (VR1)","volume":"132","author":"McIntyre","year":"2001","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0205","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1056\/NEJMcp022282","article-title":"Clinical practice. Painful sensory neuropathy","volume":"348","author":"Mendell","year":"2003","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0210","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0006-8993(00)02050-3","article-title":"Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120","volume":"861","author":"Milligan","year":"2000","journal-title":"Brain Research"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0215","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1254\/jphs.CRJ06005X","article-title":"Brain cytokines and chemokines: roles in ischemic injury and pain","volume":"100","author":"Minami","year":"2006","journal-title":"Journal of Pharmacological Sciences"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0220","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1097\/01.don.0000155259.22746.ae","article-title":"Expression and characterization of vanilloid receptor subtype 1 in human dental pulp cell cultures","volume":"31","author":"Miyamoto","year":"2005","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0225","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1744-8069-3-17","article-title":"Spinal NKCC1 blockade inhibits TRPV1-dependent referred allodynia","volume":"3","author":"Pitcher","year":"2007","journal-title":"Molecular Pain"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0230","doi-asserted-by":"crossref","first-page":"31868","DOI":"10.1074\/jbc.274.45.31868","article-title":"Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding","volume":"274","author":"Schottelius","year":"1999","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0235","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1016\/j.pain.2011.04.005","article-title":"Activation of cannabinoid receptors by the pentacyclic triterpene alpha, beta-amyrin inhibits inflammatory and neuropathic persistent pain in mice","volume":"152","author":"Simao da Silva","year":"2011","journal-title":"Pain"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0240","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1097\/00001756-200306110-00010","article-title":"Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesia","volume":"14","author":"Svensson","year":"2003","journal-title":"Neuroreport"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0245","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1124\/jpet.106.117572","article-title":"Antinociceptive pharmacology of N-(4-chlorobenzyl)-N\u2032-(4-hydroxy-3-iodo-5-methoxybenzyl) thiourea, a high-affinity competitive antagonist of the transient receptor potential vanilloid 1 receptor","volume":"321","author":"Tang","year":"2007","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0250","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1086\/517824","article-title":"Posttranscriptional down-regulation of tumor necrosis factor-alpha and interleukin-1beta production in acute meningococcal infections","volume":"177","author":"van Deuren","year":"1998","journal-title":"Journal of Infectious Diseases"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0255","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.pharmthera.2006.04.001","article-title":"Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development?","volume":"112","author":"Verri","year":"2006","journal-title":"Pharmacology & Therapeutics"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0260","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.brainres.2003.09.074","article-title":"Inhibition of MEK\/ERK 1\/2 pathway reduces pro-inflammatory cytokine interleukin-1 expression in focal cerebral ischemia","volume":"996","author":"Wang","year":"2004","journal-title":"Brain Research"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0265","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1177\/0091270005282630","article-title":"Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use","volume":"45","author":"Zhou","year":"2005","journal-title":"Journal of Clinical Pharmacology"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0270","doi-asserted-by":"crossref","first-page":"8300","DOI":"10.1523\/JNEUROSCI.2893-04.2004","article-title":"Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization","volume":"24","author":"Zhuang","year":"2004","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.brainresbull.2012.06.002_bib0275","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.pain.2004.12.022","article-title":"ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model","volume":"114","author":"Zhuang","year":"2005","journal-title":"Pain"}],"container-title":["Brain Research Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0361923012001281?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0361923012001281?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T20:15:36Z","timestamp":1759781736000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0361923012001281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":55,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S0361923012001281"],"URL":"https:\/\/doi.org\/10.1016\/j.brainresbull.2012.06.002","relation":{},"ISSN":["0361-9230"],"issn-type":[{"value":"0361-9230","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anti-nociceptive effects of Tanshinone IIA (TIIA) in a rat model of complete Freund's adjuvant (CFA)-induced inflammatory pain","name":"articletitle","label":"Article Title"},{"value":"Brain Research Bulletin","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainresbull.2012.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}