{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:19:32Z","timestamp":1789661972319,"version":"4.0.1"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research Bulletin"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.brainresbull.2015.12.004","type":"journal-article","created":{"date-parts":[[2015,12,19]],"date-time":"2015-12-19T13:30:20Z","timestamp":1450531820000},"page":"102-109","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"special_numbering":"C","title":["Evidence of anhedonia and differential reward processing in prefrontal cortex among post-withdrawal patients with prescription opiate dependence"],"prefix":"10.1016","volume":"123","author":[{"given":"A.S.","family":"Huhn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.E.","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.D.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5514-2741","authenticated-orcid":false,"given":"H.","family":"Ayaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Deneke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.M.","family":"Stankoski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.C.","family":"Bunce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainresbull.2015.12.004_bib0005","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/j.1600-0447.1982.tb06720.x","article-title":"Studies on duration of a late recovery period after chronic abuse of ethanol","volume":"66","author":"Alling","year":"1982","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0010","unstructured":"American Psychiatric Association (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Washington, DC: Author."},{"issue":"August","key":"10.1016\/j.brainresbull.2015.12.004_bib0015","first-page":"6567","article-title":"Sliding-window motion artifact rejection for functional near-infrared spectroscopy","author":"Ayaz","year":"2010","journal-title":"Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE"},{"issue":"3443","key":"10.1016\/j.brainresbull.2015.12.004_bib0020","article-title":"Using mazesuite and functional near infrared spectroscopy to study learning in spatial navigation","volume":"56","author":"Ayaz","year":"2011","journal-title":"J. Visualized Exp."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0025","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0376-8716(79)90019-X","article-title":"Persistence of a subacute withdrawal syndrome following chronic ethanol intake","volume":"4","author":"Begleiter","year":"1979","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/02791072.2000.10736099","article-title":"Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors","volume":"32","author":"Blum","year":"2000","journal-title":"J. Psychoactive Drugs"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0035","first-page":"139","article-title":"Neurogenetics and nutrigenomics of neuro-nutrient therapy for Reward Deficiency Syndrome (RDS): clinical ramifications as a function of molecular neurobiological mechanisms","volume":"3","author":"Blum","year":"2012","journal-title":"J. Addict. Res. Ther."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0040","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1176\/appi.ajp.158.12.2033","article-title":"Cannabis abuse as a risk factor for depressive symptoms","volume":"158","author":"Bovasso","year":"2001","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0045","series-title":"Startle Modification: Implications for Neuroscience, Cognitive Science and Clinical Science","first-page":"157","article-title":"Affect and the startle reflex","author":"Bradley","year":"1999"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0050","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.biopsych.2006.10.026","article-title":"Neural substrates of resisting craving during cigarette cue exposure","volume":"62","author":"Brody","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0055","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1097\/ADM.0000000000000087","article-title":"Possible evidence for re-regulation of HPA axis and brain reward systems over time in treatment in prescription opioid-dependent patients","volume":"9","author":"Bunce","year":"2015","journal-title":"J. Addict. Med."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0060","series-title":"Advances in Brain Inspired Cognitive Systems","first-page":"183","article-title":"Treatment status predicts differential prefrontal cortical responses to alcohol and natural reinforcer cues among alcohol dependent individuals","author":"Bunce","year":"2012"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0065","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1093\/ntr\/ntq118","article-title":"Effects of anhedonia on days to relapse among smokers with a history of depression: a brief report","volume":"12","author":"Cook","year":"2010","journal-title":"Nicotine Tob. Res."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0070","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00213-008-1110-2","article-title":"Dysregulation of emotional response in current and abstinent heroin users: negative heightening and positive blunting","volume":"198","author":"de Arcos","year":"2008","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0075","doi-asserted-by":"crossref","first-page":"S505","DOI":"10.1016\/j.euroneuro.2012.07.004","article-title":"Anhedonia and major depression: the role of agomelatine","volume":"22","author":"Di Giannantonio","year":"2012","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0080","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.neuroimage.2013.03.067","article-title":"Application of functional near-infrared spectroscopy in psychiatry","volume":"85","author":"Ehlis","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0085","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.neuroimage.2012.03.049","article-title":"A brief review on the history of human functional nearinfraredspectroscopy (fNIRS) development and fields of application","volume":"63","author":"Ferrari","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0090","series-title":"Patient Edition. (SCID-I\/P)","article-title":"Structured clinical interview for DSM-IV-TR axis I disorders, research version","author":"First","year":"2002"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0095","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/j.paid.2005.12.005","article-title":"BIS\/BAS personality characteristics and college students\u2019 substance use","volume":"40","author":"Franken","year":"2006","journal-title":"Personality and Individual Difference"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0100","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jad.2006.08.020","article-title":"The assessment of anhedonia in clinical and non-clinical populations: further validation of the Snaith\u2013Hamilton Pleasure Scale (SHAPS)","volume":"99","author":"Franken","year":"2007","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0105","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.neulet.2008.04.033","article-title":"Impaired response inhibition function in abstinent heroin dependents: an fMRI study","volume":"438","author":"Fu","year":"2008","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0110","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1177\/0004867413508455","article-title":"Anhedonia in substance use disorders: A systematic review of its nature, course and clinical correlates","volume":"48","author":"Garfield","year":"2014","journal-title":"Aust. N. Z. J. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0115","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1056\/NEJM198805053181806","article-title":"Cocaine and other stimulants","volume":"318","author":"Gawin","year":"1988","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0120","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0165-0327(01)00392-5","article-title":"Relationship of anhedonia and anxiety to social rank, defeat and entrapment","volume":"71","author":"Gilbert","year":"2002","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0125","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1162\/jocn.2006.18.6.932","article-title":"Functional specialization within rostral prefrontal cortex (Area 10): a meta-analysis","volume":"18","author":"Gilbert","year":"2006","journal-title":"J. Cogn. Neurosci."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0130","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1037\/0735-7044.116.2.321","article-title":"Cocaine-induced suppression of saccharin intake: a model of drug-induced devaluation of natural rewards","volume":"116","author":"Grigson","year":"2002","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0135","first-page":"127","article-title":"The neurocircuitry of impaired insight in drug addiction","volume":"2","author":"Goldstein","year":"2009","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0140","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/nrn3119","article-title":"Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications","volume":"12","author":"Goldstein","year":"2011","journal-title":"Nat. Rev. Neurosci."},{"issue":"-10","key":"10.1016\/j.brainresbull.2015.12.004_bib0145","article-title":"Anhedonia and substance dependence: clinical correlates and treatment options","volume":"2","author":"Hatzigiakoumis","year":"2011","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0150","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1055\/s-2007-1014317","article-title":"Anhedonia in schizophrenic, depressed, or alcohol-dependent patients: neurobiological correlates","volume":"27","author":"Heinz","year":"1994","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0155","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/13854040600910018","article-title":"Functional near infrared spectroscopy (fNIRS): An emerging neuroimaging technology with important applications for the study of brain disorders","volume":"21","author":"Irani","year":"2007","journal-title":"Clin. Neuropsychologist"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0160","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000086176","article-title":"Anhedonia and substance-related symptoms in detoxified substance-dependent subjects; a correlation study","volume":"52","author":"Janiri","year":"2005","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0165","first-page":"367","article-title":"The ten\u2013twenty electrode system of the International Federation","volume":"10","author":"Jasper","year":"1958","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0170","volume":"Vol. I","author":"Johnston","year":"2011"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0175","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0893-133X(00)00195-0","article-title":"Drug Addiction, dysregulation of reward, and allostasis","volume":"24","author":"Koob","year":"2001","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0180","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1176\/appi.ajp.2007.05030503","article-title":"Stress, dysregulation of drug reward pathways, and the transition to drug dependence","volume":"164","author":"Koob","year":"2007","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0185","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/npp.2009.110","article-title":"Neurocircuitry of addiction","volume":"35","author":"Koob","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0190","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.pneurobio.2004.03.006","article-title":"The functional neuroanatomy of the human orbitofrontal cortex: evidence from neuroimaging and neuropsychology","volume":"72","author":"Kringelbach","year":"2004","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0195","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1111\/j.1460-9568.2010.07590.x","article-title":"Common biology of craving across legal and illegal drugs\u2013a quantitative meta-analysis of cue-reactivity brain response","volume":"33","author":"K\u00fchn","year":"2011","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0200","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1037\/0003-066X.50.5.372","article-title":"The emotion probe: studies of motivation and attention","volume":"50","author":"Lang","year":"1995","journal-title":"Am. Psychol."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0205","series-title":"Technical Report A-8","article-title":"International affective picture system (IAPS): affective ratings of pictures and instruction manual","author":"Lang","year":"2008"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0210","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1093\/ntr\/ntp098","article-title":"Relations between anhedonia and smoking motivation","volume":"11","author":"Leventhal","year":"2009","journal-title":"Nicotine. Tob. Res."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0215","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1037\/a0021964","article-title":"Anhedonia associated with stimulant use and dependence in a population-based sample of american adults","volume":"18","author":"Leventhal","year":"2010","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0220","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0165-0327(96)00065-1","article-title":"Vulnerability to depression: a model centered on anhedonia","volume":"41","author":"Loas","year":"1996","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0225","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1001\/archgenpsychiatry.2008.522","article-title":"Responsiveness to drug cues and natural rewards in opiate addiction: associations with later heroin use","volume":"66","author":"Lubman","year":"2009","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0230","first-page":"17","article-title":"Postcocaine anhedonia: an animal model of cocaine withdrawal","volume":"4","author":"Markou","year":"1991","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0235","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1001\/archpsyc.1973.01750320112017","article-title":"Methadone\u2014a reevaluation","volume":"28","author":"Martin","year":"1973","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0240","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/BF00408180","article-title":"Tolerance to and physical dependence on morphine in rats","volume":"4","author":"Martin","year":"1963","journal-title":"Psychopharmacologia"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0245","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1080\/00952990701877078","article-title":"Temperament and character inventory dimensions and anhedonia in detoxified substance-dependent subjects","volume":"34","author":"Martinotti","year":"2008","journal-title":"Am. J. Drug Alcohol Abuse"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0250","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1080\/10826080701202429","article-title":"Alcohol protracted withdrawal syndrome: the role of anhedonia","volume":"43","author":"Martinotti","year":"2008","journal-title":"Subst. Use Misuse"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0255","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.pnpbp.2011.01.013","article-title":"Acetyl-l-Carnitine in the treatment of anhedonia, melancholic and negative symptoms in alcohol dependent subjects","volume":"35","author":"Martinotti","year":"2011","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0260","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1192\/bjp.134.4.382","article-title":"A new depression scale designed to be sensitive to change","volume":"134","author":"Montgomery","year":"1979","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0265","unstructured":"Muhuri, P.K., Gfroerer, J.C., Davies M.C., 2013. Associations of nonmedical pain reliever use and initiation of heroin use in the United States, CBHSQ [Center for Behavioral Health Statistics and Quality] Data Review, http:\/\/www.samhsa.gov\/data\/2k13\/DataReview\/DR006\/nonmedical-pain-reliever-use-2013.htm."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0270","first-page":"S17","article-title":"A potential biomarker for addiction","volume":"38","author":"O'Brien","year":"2012","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0275","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1177\/026988119801200103","article-title":"Conditioning factors in drug abuse: can they explain compulsion?","volume":"12","author":"O'Brien","year":"1998","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0280","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.neuroimage.2003.08.026","article-title":"Three-dimensional probabilistic anatomical cranio-cerebral correlation via the international 10-20 system oriented for transcranial functional brain mapping","volume":"21","author":"Okamoto","year":"2004","journal-title":"Neuroimage"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0285","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2014.00173","article-title":"Allostasis as a conceptual framework linking bipolar disorder and addiction","volume":"5","author":"Pettorruso","year":"2014","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0290","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.neuroimage.2008.05.046","article-title":"Neural correlates of voluntary and involuntary risk taking in the human brain: an fMRI study of the balloon analogue risk task (BART)","volume":"42","author":"Rao","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0295","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.neuroimage.2013.05.004","article-title":"A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology","volume":"85","author":"Scholkmann","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0300","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1017\/S0033291700026428","article-title":"Anhedonia: a neglected symptom of psychopathology","volume":"23","author":"Snaith","year":"1993","journal-title":"Psychol. Med."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0305","doi-asserted-by":"crossref","first-page":"99-103.\u200b","DOI":"10.1192\/bjp.167.1.99","article-title":"A scale for the assessment of hedonic tone: the snaith-hamilton pleasure scale","volume":"167","author":"Snaith","year":"1995","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0310","unstructured":"Substance Abuse and Mental Health Services Administration, (2013). Results from the 2012 Nation Survey on Drug Use and Health: summary of National Findings (NSDUH Series H-46, HHS Publication No. SMA 13-4795). Rockville, MD: Substance Abuse and Mental Health Services Administration."},{"issue":"1","key":"10.1016\/j.brainresbull.2015.12.004_bib0315","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1521-0391.2011.00186.x","article-title":"Compliance with buprenorphine medication-assisted treatment and relapse to opioid use","volume":"21","author":"Tkacz","year":"2012","journal-title":"Am. J. Addict."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0320","doi-asserted-by":"crossref","first-page":"5181","DOI":"10.1073\/pnas.0610178104","article-title":"Prefrontal\/accumbal catecholamine system determines motivational salience attribution to both reward-and aversion-related stimuli","volume":"104","author":"Ventura","year":"2007","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0325","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1111\/j.1369-1600.2011.00372.x","article-title":"Beyond cue reactivity: blunted brain responses to pleasant stimuli predict long-term smoking abstinence","volume":"17","author":"Versace","year":"2011","journal-title":"Addict. Biol."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0330","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0166-2236(97)01132-6","article-title":"Non-invasive optical spectroscopy and imaging of human brain function","volume":"20","author":"Villringer","year":"1997","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0335","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1006\/nlme.2002.4099","article-title":"Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies","volume":"78","author":"Volkow","year":"2002","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0340","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.neuroimage.2009.08.020","article-title":"Alterations in the processing of non-drug-related affective stimuli in abstinence heroin addicts","volume":"49","author":"Wang","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0345","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/08897079809511386","article-title":"Reliability of form 90D: an instrument for quantifying drug use","volume":"19","author":"Westerberg","year":"1998","journal-title":"Subst. Abuse"},{"key":"10.1016\/j.brainresbull.2015.12.004_bib0350","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.drugalcdep.2008.07.012","article-title":"Neurobiological substrates of cue-elicited craving and anhedonia in recently abstinent opioid-dependent males","volume":"99","author":"Zijlstra","year":"2009","journal-title":"Drug Alcohol Depend."}],"container-title":["Brain Research Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0361923015300757?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0361923015300757?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T20:22:54Z","timestamp":1759782174000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0361923015300757"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":70,"alternative-id":["S0361923015300757"],"URL":"https:\/\/doi.org\/10.1016\/j.brainresbull.2015.12.004","relation":{},"ISSN":["0361-9230"],"issn-type":[{"value":"0361-9230","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evidence of anhedonia and differential reward processing in prefrontal cortex among post-withdrawal patients with prescription opiate dependence","name":"articletitle","label":"Article Title"},{"value":"Brain Research Bulletin","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainresbull.2015.12.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}