{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T03:32:37Z","timestamp":1782271957531,"version":"3.54.5"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81720108015"],"award-info":[{"award-number":["81720108015"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81671221"],"award-info":[{"award-number":["81671221"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81671380"],"award-info":[{"award-number":["81671380"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81930031"],"award-info":[{"award-number":["81930031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81502173"],"award-info":[{"award-number":["81502173"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81801231"],"award-info":[{"award-number":["81801231"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82001317"],"award-info":[{"award-number":["82001317"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81901525"],"award-info":[{"award-number":["81901525"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81771221"],"award-info":[{"award-number":["81771221"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin City","doi-asserted-by":"publisher","award":["15ZXLCSY00060"],"award-info":[{"award-number":["15ZXLCSY00060"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin City","doi-asserted-by":"publisher","award":["17JCZDJC35900"],"award-info":[{"award-number":["17JCZDJC35900"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin City","doi-asserted-by":"publisher","award":["15ZXJZSY00040"],"award-info":[{"award-number":["15ZXJZSY00040"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin City","doi-asserted-by":"publisher","award":["2018KJ052"],"award-info":[{"award-number":["2018KJ052"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Research Bulletin"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.brainresbull.2021.04.024","type":"journal-article","created":{"date-parts":[[2021,4,28]],"date-time":"2021-04-28T06:30:43Z","timestamp":1619591443000},"page":"108-119","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["A novel rat model of chronic subdural hematoma: Induction of inflammation and angiogenesis in the subdural space mimicking human-like features of progressively expanding hematoma"],"prefix":"10.1016","volume":"172","author":[{"given":"Xin","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenying","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueshan","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanjian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziwei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuang","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guili","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongcai","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianning","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainresbull.2021.04.024_bib0005","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.jim.2008.11.016","article-title":"Matrigel cytometry: a novel method for quantifying angiogenesis in vivo","volume":"342","author":"Adini","year":"2009","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0010","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.3171\/2016.4.JNS152642","article-title":"Bilateral chronic subdural hematoma: unilateral or bilateral drainage?","volume":"126","author":"Andersen-Ranberg","year":"2017","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0070459","article-title":"Angiopoietin-2 is critical for cytokine-induced vascular leakage","volume":"8","author":"Benest","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0020","first-page":"2359","article-title":"Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice","volume":"119","author":"Bhandarkar","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0025","doi-asserted-by":"crossref","first-page":"9618","DOI":"10.1523\/JNEUROSCI.0914-18.2018","article-title":"Angiopoietin\/Tie2 axis regulates the age-at-injury cerebrovascular response to traumatic brain injury","volume":"38","author":"Brickler","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0030","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.brainres.2006.10.083","article-title":"Tight junction protein expression and barrier properties of immortalized mouse brain microvessel endothelial cells","volume":"1130","author":"Brown","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0035","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s10456-012-9324-7","article-title":"Matrigel plug assay: evaluation of the angiogenic response by reverse transcription-quantitative PCR","volume":"16","author":"Coltrini","year":"2013","journal-title":"Angiogenesis"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0040","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1172\/JCI20465","article-title":"VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment","volume":"113","author":"Cursiefen","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0045","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1179\/1743132813Y.0000000279","article-title":"Experimental models of chronic subdural hematoma","volume":"36","author":"D\u2019Abbondanza","year":"2014","journal-title":"Neurol. Res."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0050","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s10143-011-0349-y","article-title":"The surgical management of chronic subdural hematoma","volume":"35","author":"Ducruet","year":"2012","journal-title":"Neurosurg. Rev."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0055","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s12974-017-0881-y","article-title":"Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy","volume":"14","author":"Edlmann","year":"2017","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0060","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3171\/jns.2004.100.1.0024","article-title":"Inflammation markers and risk factors for recurrence in 35 patients with a posttraumatic chronic subdural hematoma: a prospective study","volume":"100","author":"Frati","year":"2004","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0065","first-page":"69","article-title":"The origin ofsubdural neomembranes. II. Fine structural of neomembranes","volume":"92","author":"Friede","year":"1978","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0070","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1089\/neu.2010.1498","article-title":"Activation of PI3 kinase\/Akt signaling in chronic subdural hematoma outer membranes","volume":"28","author":"Funai","year":"2011","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0075","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.expneurol.2018.06.001","article-title":"Endothelial colony-forming cell-derived exosomes restore blood-brain barrier continuity in mice subjected to traumatic brain injury","volume":"307","author":"Gao","year":"2018","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0080","doi-asserted-by":"crossref","first-page":"12147","DOI":"10.18632\/aging.102550","article-title":"Hematoma-derived exosomes of chronic subdural hematoma promote abnormal angiogenesis and inhibit hematoma absorption through miR-144-5p","volume":"11","author":"Gao","year":"2019","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0085","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/ar.1092300103","article-title":"On the question of a subdural space","volume":"230","author":"Haines","year":"1991","journal-title":"Anat. Rec."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0090","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1227\/00006123-199301000-00017","article-title":"The \"subdural\" space: a new look at an outdated concept","volume":"32","author":"Haines","year":"1993","journal-title":"Neurosurgery"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0095","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s00415-009-0048-6","article-title":"Procollagen propeptides in chronic subdural hematoma reveal sustained dural collagen synthesis after head injury","volume":"256","author":"Heula","year":"2009","journal-title":"J. Neurol."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0100","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1089\/neu.2005.22.518","article-title":"Increased mRNA expression of VEGF within the hematoma and imbalance of angiopoietin-1 and -2 mRNA within the neomembranes of chronic subdural hematoma","volume":"22","author":"Hohenstein","year":"2005","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0105","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.wneu.2018.05.037","article-title":"Pathophysiology and nonsurgical treatment of chronic subdural hematoma: from past to present to future","volume":"116","author":"Holl","year":"2018","journal-title":"World Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0110","doi-asserted-by":"crossref","first-page":"e753","DOI":"10.1016\/j.wneu.2018.07.039","article-title":"Elevated serum fibrinogen degradation products on admission is a novel predictive factor for recurrence of chronic subdural hematoma","volume":"118","author":"Hori","year":"2018","journal-title":"World Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0115","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1089\/neu.2014.3724","article-title":"Role of matrix metalloproteinase-2, matrix metalloproteinase-9, and vascular endothelial growth factor in the development of chronic subdural hematoma","volume":"33","author":"Hua","year":"2016","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0120","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1089\/neu.2013.2996","article-title":"Intracerebroventricular transplantation of ex vivo expanded endothelial colony-forming cells restores blood-brain barrier integrity and promotes angiogenesis of mice with traumatic brain injury","volume":"30","author":"Huang","year":"2013","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0125","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3389\/fnagi.2019.00325","article-title":"Effect of different factors on the short-term outcome of Chinese patients with primary chronic subdural hematoma at different age groups: a two-center retrospective study","volume":"11","author":"Huang","year":"2019","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0130","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1080\/14656566.2020.1713095","article-title":"Drug treatment of chronic subdural hematoma","volume":"21","author":"Huang","year":"2020","journal-title":"Expert Opin. Pharmacother."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0135","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1093\/brain\/69.3.157","article-title":"Subdural haemorrhage, cysts and false membranes; illustrating the influence of intrinsic factors in disease when development of the body is normal","volume":"69","author":"Inglis","year":"1946","journal-title":"Brain"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0140","doi-asserted-by":"crossref","DOI":"10.1089\/neu.2020.7042","article-title":"Expression of angiopoietins and angiogenic signaling pathway molecules in chronic subdural hematomas","author":"Isaji","year":"2020","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0145","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3171\/jns.1976.45.1.0026","article-title":"Role of local hyperfibrinolysis in the etiology of chronic subdural hematoma","volume":"45","author":"Ito","year":"1976","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0150","doi-asserted-by":"crossref","first-page":"332","DOI":"10.3171\/2013.3.JNS122162","article-title":"Nonsurgical treatment of chronic subdural hematoma with tranexamic acid","volume":"119","author":"Kageyama","year":"2013","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0155","doi-asserted-by":"crossref","first-page":"353","DOI":"10.3171\/2012.10.JNS12327","article-title":"PlGF and sVEGFR-1 in chronic subdural hematoma: implications for hematoma development","volume":"118","author":"Kalamatianos","year":"2013","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0160","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/978-1-4939-9133-4_18","article-title":"Matrigel plug assay for in vivo evaluation of angiogenesis","volume":"1952","author":"Kastana","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0165","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3171\/jns.2006.104.1.79","article-title":"Tissue plasminogen activator in chronic subdural hematomas as a predictor of recurrence","volume":"104","author":"Katano","year":"2006","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0170","doi-asserted-by":"crossref","first-page":"810","DOI":"10.2176\/nmc.52.810","article-title":"Measurement of inflammatory cytokines and thrombomodulin in chronic subdural hematoma","volume":"52","author":"Kitazono","year":"2012","journal-title":"Neurol. Med. Chir. (Tokyo)"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0175","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/nrneurol.2014.163","article-title":"Chronic subdural haematoma: modern management and emerging therapies","volume":"10","author":"Kolias","year":"2014","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0180","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1111\/1440-1681.12587","article-title":"Characterisation of a mouse cerebral microvascular endothelial cell line (bEnd.3) after oxygen glucose deprivation and reoxygenation","volume":"43","author":"Ku","year":"2016","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0185","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1080\/026990598121972","article-title":"Origin of chronic subdural haematoma and relation to traumatic subdural lesions","volume":"12","author":"Lee","year":"1998","journal-title":"Brain Inj."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0190","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jns.2014.04.009","article-title":"Effects of atorvastatin on the inflammation regulation and elimination of subdural hematoma in rats","volume":"341","author":"Li","year":"2014","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0195","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/0092-8674(90)90009-4","article-title":"Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene","volume":"62","author":"Montesano","year":"1990","journal-title":"Cell"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0200","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1017\/S1431927607070286","article-title":"Morphological aspects of the traumatic chronic subdural hematoma capsule: SEM studies","volume":"13","author":"Moskala","year":"2007","journal-title":"Microsc. Microanal."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0205","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s007010050008","article-title":"Expression of matrix metalloproteinases in the chronic subdural haematoma membrane","volume":"142","author":"Nakagawa","year":"2000","journal-title":"Acta Neurochir. (Wien)"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0210","doi-asserted-by":"crossref","first-page":"910","DOI":"10.3171\/jns.1994.81.6.0910","article-title":"Characterization of local hyperfibrinolysis in chronic subdural hematomas by SDS-PAGE and immunoblot","volume":"81","author":"Nomura","year":"1994","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0215","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.neulet.2012.11.011","article-title":"Activation of JAK-STAT3 signaling pathway in chronic subdural hematoma outer membranes","volume":"534","author":"Osuka","year":"2013","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0220","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0233643","article-title":"Expression of high mobility group B1 and toll-like receptor-nuclear factor kappaB signaling pathway in chronic subdural hematomas","volume":"15","author":"Osuka","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0225","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.clineuro.2010.11.014","article-title":"Fibrinogen and D-dimer analysis of chronic subdural hematomas and computed tomography findings: a prospective study","volume":"113","author":"Park","year":"2011","journal-title":"Clin. Neurol. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0230","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.brainres.2015.08.017","article-title":"A rat model of chronic subdural hematoma: insight into mechanisms of revascularization and inflammation","volume":"1625","author":"Quan","year":"2015","journal-title":"Brain Res."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0235","first-page":"1","article-title":"The incidence of chronic subdural hematomas from 1990 to 2015 in a defined Finnish population","author":"Rauhala","year":"2019","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0240","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1172\/JCI17712","article-title":"Proinflammatory functions of vascular endothelial growth factor in alloimmunity","volume":"112","author":"Reinders","year":"2003","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.wneu.2019.05.063","article-title":"Surgical treatment of chronic subdural hematoma: predicting recurrence and cure","author":"Ridwan","year":"2019","journal-title":"World Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0250","doi-asserted-by":"crossref","first-page":"357","DOI":"10.2176\/nmc.oa2013-0019","article-title":"Expression of the TGF-beta-ALK-1 pathway in dura and the outer membrane of chronic subdural hematomas","volume":"54","author":"Saito","year":"2014","journal-title":"Neurol. Med. Chir. (Tokyo)"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0255","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1136\/jnnp.74.4.522","article-title":"High concentrations of procollagen propeptides in chronic subdural haematoma and effusion","volume":"74","author":"Sajanti","year":"2003","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0260","doi-asserted-by":"crossref","first-page":"6788","DOI":"10.1073\/pnas.92.15.6788","article-title":"Thrombospondin 1 expression in transformed endothelial cells restores a normal phenotype and suppresses their tumorigenesis","volume":"92","author":"Sheibani","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0265","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1054\/jocn.2000.0951","article-title":"Vascular endothelial growth factor in chronic subdural haematomas","volume":"8","author":"Shono","year":"2001","journal-title":"J. Clin. Neurosci."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0270","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1007\/s00011-012-0476-0","article-title":"Local and systemic pro-inflammatory and anti-inflammatory cytokine patterns in patients with chronic subdural hematoma: a prospective study","volume":"61","author":"Stanisic","year":"2012","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0275","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00701-011-1203-2","article-title":"Chemokines as markers of local inflammation and angiogenesis in patients with chronic subdural hematoma: a prospective study","volume":"154","author":"Stanisic","year":"2012","journal-title":"Acta Neurochir. (Wien)"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0280","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s007010050057","article-title":"Inflammatory cytokines locally elevated in chronic subdural haematoma","volume":"140","author":"Suzuki","year":"1998","journal-title":"Acta Neurochir. (Wien)"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0285","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1016\/j.wneu.2015.08.044","article-title":"Nonsurgical treatment of chronic subdural hematoma with steroids","volume":"84","author":"Thotakura","year":"2015","journal-title":"World Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0290","doi-asserted-by":"crossref","first-page":"290","DOI":"10.3171\/JNS-07\/08\/0290","article-title":"The role of exudation in chronic subdural hematomas","volume":"107","author":"Tokmak","year":"2007","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0295","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s007010200047","article-title":"Vascular endothelial growth-permeability factor in granulation tissue of chronic subdural haematomas","volume":"144","author":"Vaquero","year":"2002","journal-title":"Acta Neurochir. (Wien)"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0300","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s10143-006-0019-7","article-title":"Local elevation of the anti-inflammatory interleukin-10 in the pathogenesis of chronic subdural hematoma","volume":"29","author":"Wada","year":"2006","journal-title":"Neurosurg. Rev."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0305","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1089\/neu.2009.1057","article-title":"Membrane neovascularization and drainage of subdural hematoma in a rat model","volume":"27","author":"Wang","year":"2010","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0310","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jns.2013.11.005","article-title":"Effects of atorvastatin on chronic subdural hematoma: a preliminary report from three medical centers","volume":"336","author":"Wang","year":"2014","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0315","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jns.2016.01.017","article-title":"Atorvastatin enhances angiogenesis to reduce subdural hematoma in a rat model","volume":"362","author":"Wang","year":"2016","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0320","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1007\/s007010170035","article-title":"Specific pattern of growth factor distribution in chronic subdural hematoma (CSH): evidence for an angiogenic disease","volume":"143","author":"Weigel","year":"2001","journal-title":"Acta Neurochir. (Wien)"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0325","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/0092-8674(89)90343-7","article-title":"Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment","volume":"57","author":"Williams","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0330","article-title":"Improvements in flow cytometry-based cytotoxicity assay","author":"Wu","year":"2020","journal-title":"Cytometry A"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0335","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1186\/s12974-017-0934-2","article-title":"Anti-inflammatory and immunomodulatory mechanisms of atorvastatin in a murine model of traumatic brain injury","volume":"14","author":"Xu","year":"2017","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0340","article-title":"Conformation-dependent blockage of activated VWF improved outcomes of traumatic brain injury in mice","author":"Xu","year":"2020","journal-title":"Blood"},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0345","doi-asserted-by":"crossref","first-page":"330","DOI":"10.4103\/1793-5482.145102","article-title":"Chronic subdural hematoma","volume":"11","author":"Yadav","year":"2016","journal-title":"Asian J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0350","doi-asserted-by":"crossref","first-page":"298","DOI":"10.3171\/jns.1983.59.2.0298","article-title":"The role of endothelial gap junctions in the enlargement of chronic subdural hematomas","volume":"59","author":"Yamashima","year":"1983","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0355","doi-asserted-by":"crossref","first-page":"10505","DOI":"10.1096\/fj.201802758RRR","article-title":"Inhibition of intracranial hemangioma growth and hemorrhage by TNFSF15","volume":"33","author":"Yang","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0360","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.bbr.2016.05.055","article-title":"Subdural hematoma decompression model: a model of traumatic brain injury with ischemic-reperfusional pathophysiology: a review of the literature","volume":"340","author":"Yokobori","year":"2018","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.brainresbull.2021.04.024_bib0365","doi-asserted-by":"crossref","first-page":"10087","DOI":"10.1002\/jcb.28292","article-title":"The influence of receptor activity-modifying protein-1 overexpression on angiogenesis in mouse brain capillary endothelial cells","volume":"120","author":"Zhang","year":"2019","journal-title":"J. Cell. Biochem."}],"container-title":["Brain Research Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0361923021001271?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0361923021001271?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T08:59:02Z","timestamp":1778749142000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0361923021001271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":73,"alternative-id":["S0361923021001271"],"URL":"https:\/\/doi.org\/10.1016\/j.brainresbull.2021.04.024","relation":{},"ISSN":["0361-9230"],"issn-type":[{"value":"0361-9230","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel rat model of chronic subdural hematoma: Induction of inflammation and angiogenesis in the subdural space mimicking human-like features of progressively expanding hematoma","name":"articletitle","label":"Article Title"},{"value":"Brain Research Bulletin","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brainresbull.2021.04.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}