{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:32:08Z","timestamp":1791196328382,"version":"4.1.0"},"reference-count":299,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research Reviews"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1016\/j.brainresrev.2009.06.003","type":"journal-article","created":{"date-parts":[[2009,6,24]],"date-time":"2009-06-24T14:18:09Z","timestamp":1245853089000},"page":"185-209","source":"Crossref","is-referenced-by-count":112,"title":["Bipolar disorder and mechanisms of action of mood stabilizers"],"prefix":"10.1016","volume":"61","author":[{"given":"Stanley I.","family":"Rapoport","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mireille","family":"Basselin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung-Wook","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagadeesh S.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brainresrev.2009.06.003_bib1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1001\/archpsyc.1995.03950140032004","article-title":"Switching from \u2018unipolar\u2019 to bipolar II. An 11-year prospective study of clinical and temperamental predictors in 559 patients","volume":"52","author":"Akiskal","year":"1995","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib2","first-page":"154","article-title":"Pharmacogenetics of lithium response in bipolar disorder","volume":"24","author":"Alda","year":"1999","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib3","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0165-0173(96)00007-0","article-title":"Inositol monophosphatase, the putative therapeutic target for lithium","volume":"22","author":"Atack","year":"1996","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib4","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1097\/00004647-200110000-00001","article-title":"An energy budget for signaling in the grey matter of the brain","volume":"21","author":"Attwell","year":"2001","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib5","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1042\/bst0180503","article-title":"Receptor-mediated activation of phospholipase A2 and arachidonic acid release in signal transduction","volume":"18","author":"Axelrod","year":"1990","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib6","doi-asserted-by":"crossref","first-page":"7737","DOI":"10.1074\/jbc.270.13.7737","article-title":"Functional analysis of the proximal 5\u2032-flanking region of the N-methyl-d-aspartate receptor subunit gene, NMDAR1","volume":"270","author":"Bai","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib7","doi-asserted-by":"crossref","first-page":"7951","DOI":"10.1073\/pnas.95.14.7951","article-title":"Functional coupling between secretory phospholipase A2 and cyclooxygenase-2 and its regulation by cytosolic group IV phospholipase A2","volume":"95","author":"Balsinde","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib8","series-title":"Basic Neurochemistry","first-page":"979","article-title":"Biochemical hypotheses of mood and anxiety disorders","author":"Barchas","year":"1994"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib9","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/sj.mp.4001268","article-title":"Evidence that a single nucleotide polymorphism in the promoter of the G protein receptor kinase 3 gene is associated with bipolar disorder","volume":"8","author":"Barrett","year":"2003","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib10","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1046\/j.1471-4159.2003.01811.x","article-title":"Chronic lithium administration potentiates brain arachidonic acid signaling at rest and during cholinergic activation in awake rats","volume":"85","author":"Basselin","year":"2003","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib11","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1038\/sj.npp.1300671","article-title":"Chronic lithium chloride administration to unanesthetized rats attenuates brain dopamine D2-like receptor-initiated signaling via arachidonic acid","volume":"30","author":"Basselin","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib12","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/sj.npp.1300611","article-title":"Chronic lithium administration to rats selectively modifies 5-HT2A\/2C receptor-mediated brain signaling via arachidonic acid","volume":"30","author":"Basselin","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib13","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1038\/sj.npp.1300920","article-title":"Chronic lithium chloride administration attenuates brain NMDA receptor-initiated signaling via arachidonic acid in unanesthetized rats","volume":"31","author":"Basselin","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib14","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00213-006-0425-0","article-title":"Chronic lithium chloride administration to rats elevates glucose metabolism in wide areas of brain, while potentiating negative effects on metabolism of dopamine D(2)-like receptor stimulation","volume":"187","author":"Basselin","year":"2006","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib15","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1111\/j.1471-4159.2005.03612.x","article-title":"Resting and arecoline-stimulated brain metabolism and signaling involving arachidonic acid are altered in the cyclooxygenase-2 knockout mouse","volume":"96","author":"Basselin","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib16","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.biopsych.2007.04.021","article-title":"Chronic carbamazepine administration reduces N-methyl-d-aspartate receptor-initiated signaling via arachidonic acid in rat brain","volume":"62","author":"Basselin","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib17","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1111\/j.1471-4159.2007.04593.x","article-title":"Chronic lithium administration attenuates up-regulated brain arachidonic acid metabolism in a rat model of neuroinflammation","volume":"102","author":"Basselin","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib18","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1007\/s11064-007-9372-3","article-title":"Flurbiprofen, a cyclooxygenase inhibitor, reduces the brain arachidonic acid signal in response to the cholinergic muscarinic agonist, arecoline, in awake rats","volume":"32","author":"Basselin","year":"2007","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib19","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1007\/s11064-008-9700-2","article-title":"Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats","volume":"33","author":"Basselin","year":"2008","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib20","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1007\/s11064-008-9595-y","article-title":"Chronic carbamazepine administration attenuates dopamine D2-like receptor-initiated signaling via arachidonic acid in rat brain","volume":"33","author":"Basselin","year":"2008","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib21","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1038\/npp.2008.227","article-title":"Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice","volume":"34","author":"Basselin","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib23","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/sj.mp.4002012","article-title":"A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder","volume":"13","author":"Baum","year":"2008","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib24","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1042\/bj3230281","article-title":"Cytosolic phospholipase A2 is coupled to muscarinic receptors in the human astrocytoma cell line 1321N1: characterization of the transducing mechanism","volume":"323","author":"Bayon","year":"1997","journal-title":"Biochem. J."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib25","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1385\/MN:32:1:089","article-title":"Lipid signaling in neural plasticity, brain repair, and neuroprotection","volume":"32","author":"Bazan","year":"2005","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib26","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1097\/MCO.0b013e32802b7030","article-title":"Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection","volume":"10","author":"Bazan","year":"2007","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib27","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/0163-7827(81)90092-8","article-title":"Rapid release of free arachidonic acid in the central nervous system due to stimulation","volume":"20","author":"Bazan","year":"1981","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib28","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1089\/neu.1995.12.791","article-title":"Mediators of injury in neurotrauma: intracellular signal transduction and gene expression","volume":"12","author":"Bazan","year":"1995","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib29","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s00213-005-0059-7","article-title":"Chronic valproate does not alter the kinetics of docosahexaenoic acid within brain phospholipids of the unanesthetized rat","volume":"182","author":"Bazinet","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib30","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.biopsych.2005.07.024","article-title":"Chronic carbamazepine decreases the incorporation rate and turnover of arachidonic Acid but not docosahexaenoic acid in brain phospholipids of the unanesthetized rat: relevance to bipolar disorder","volume":"59","author":"Bazinet","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib31","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s00213-005-0272-4","article-title":"Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl-CoA by brain microsomal long-chain fatty acyl-CoA synthetases: relevance to bipolar disorder","volume":"184","author":"Bazinet","year":"2006","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib32","doi-asserted-by":"crossref","first-page":"483","DOI":"10.2165\/00019053-200119050-00004","article-title":"The lifetime cost of bipolar disorder in the US: an estimate for new cases in 1998","volume":"19","author":"Begley","year":"2001","journal-title":"Pharmacoeconomics"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib33","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1056\/NEJMra035354","article-title":"Bipolar disorder","volume":"351","author":"Belmaker","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib34","doi-asserted-by":"crossref","first-page":"727","DOI":"10.2165\/00023210-200721090-00003","article-title":"Bipolar II disorder: epidemiology, diagnosis and management","volume":"21","author":"Benazzi","year":"2007","journal-title":"CNS Drugs"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib36","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1001\/archpsyc.1989.01810050035006","article-title":"The cholinergic rapid eye movement sleep induction test with RS-86. State or trait marker of depression?","volume":"46","author":"Berger","year":"1989","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib37","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1042\/bj2060587","article-title":"Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands","volume":"206","author":"Berridge","year":"1982","journal-title":"Biochem. J."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib38","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0092-8674(89)90026-3","article-title":"Neural and developmental actions of lithium: a unifying hypothesis","volume":"59","author":"Berridge","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib39","doi-asserted-by":"crossref","first-page":"3107","DOI":"10.1016\/j.lfs.2005.01.003","article-title":"Carbamazepine is an inhibitor of histone deacetylases","volume":"76","author":"Beutler","year":"2005","journal-title":"Life Sci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib40","doi-asserted-by":"crossref","first-page":"871","DOI":"10.2165\/00023210-200115110-00005","article-title":"Olanzapine: a review of its use in the treatment of bipolar I disorder","volume":"15","author":"Bhana","year":"2001","journal-title":"CNS Drugs"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib41","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1007\/s00213-005-2208-4","article-title":"D2 but not D1 dopamine receptor stimulation augments brain signaling involving arachidonic acid in unanesthetized rats","volume":"180","author":"Bhattacharjee","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib42","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s00213-008-1073-3","article-title":"Imaging apomorphine stimulation of brain arachidonic acid signaling via D2-like receptors in unanesthetized rats","volume":"197","author":"Bhattacharjee","year":"2008","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib43","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.nurt.2006.11.007","article-title":"Valproic acid: second generation","volume":"4","author":"Bialer","year":"2007","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib44","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/00007691-199802000-00010","article-title":"Does carbamazepine have a narrow therapeutic plasma concentration range?","volume":"20","author":"Bialer","year":"1998","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib45","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/S0006-3223(01)01228-8","article-title":"Association of 5-HT(2A) receptor gene polymorphism with major affective disorders: the case of a subgroup of bipolar disorder with low suicide risk","volume":"51","author":"Bonnier","year":"2002","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib46","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/j.1471-4159.2007.04558.x","article-title":"Arachidonic acid metabolism in brain physiology and pathology: lessons from genetically altered mouse models","volume":"102","author":"Bosetti","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib47","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/sj.mp.4001111","article-title":"Chronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E(2) concentration in rat brain","volume":"7","author":"Bosetti","year":"2002","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib48","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0361-9230(01)00744-4","article-title":"Analysis of gene expression with cDNA microarrays in rat brain after 7 and 42 days of oral lithium administration","volume":"57","author":"Bosetti","year":"2002","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib49","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1046\/j.1471-4159.2003.01701.x","article-title":"Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain","volume":"85","author":"Bosetti","year":"2003","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib50","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1111\/j.1471-4159.2004.02829.x","article-title":"Prostaglandin E2 and microsomal prostaglandin E synthase-2 expression are decreased in the cyclooxygenase-2-deficient mouse brain despite compensatory induction of cyclooxygenase-1 and Ca2+-dependent phospholipase A2","volume":"91","author":"Bosetti","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib51","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.brainresbull.2005.01.004","article-title":"Microarray analysis of rat brain gene expression after chronic administration of sodium valproate","volume":"65","author":"Bosetti","year":"2005","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib52","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1176\/appi.ajp.157.12.1925","article-title":"Affective disorders and suicide risk: a reexamination","volume":"157","author":"Bostwick","year":"2000","journal-title":"Am. J. Psychiatry"},{"issue":"Suppl. 3","key":"10.1016\/j.brainresrev.2009.06.003_bib53","first-page":"25","article-title":"Predictors of response to divalproex and lithium","volume":"56","author":"Bowden","year":"1995","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib54","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1017\/S1461145703003535","article-title":"Acute and maintenance treatment with mood stabilizers","volume":"6","author":"Bowden","year":"2003","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib55","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1001\/jama.1994.03510360044034","article-title":"Efficacy of divalproex vs lithium and placebo in the treatment of mania. The Depakote Mania Study Group","volume":"271","author":"Bowden","year":"1994","journal-title":"JAMA"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib56","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4088\/JCP.v66n0116","article-title":"A randomized, double-blind, placebo-controlled efficacy and safety study of quetiapine or lithium as monotherapy for mania in bipolar disorder","volume":"66","author":"Bowden","year":"2005","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib57","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.4088\/JCP.v66n1217","article-title":"Focus on bipolar disorder treatment","volume":"66","author":"Bowden","year":"2005","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib58","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S1474-4422(03)00498-8","article-title":"NSAIDs and Alzheimer's disease: how far to generalise from trials?","volume":"2","author":"Breitner","year":"2003","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib59","series-title":"Psychopharmacology: The Third Generation of Progress","first-page":"553","article-title":"Mechanisms of action of lithium in affective illness: basic and clinical implications","author":"Bunney","year":"1987"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib60","doi-asserted-by":"crossref","first-page":"S237","DOI":"10.1194\/jlr.R800033-JLR200","article-title":"Phospholipase A2 structure\/function, mechanism, and signaling","volume":"50 Suppl","author":"Burke","year":"2009","journal-title":"J. Lipid Res."},{"issue":"Suppl. 1","key":"10.1016\/j.brainresrev.2009.06.003_bib61","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1038\/sj.mp.4001019","article-title":"Role of the cholinergic muscarinic system in bipolar disorder and related mechanism of action of antipsychotic agents","volume":"7","author":"Bymaster","year":"2002","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib62","doi-asserted-by":"crossref","first-page":"349","DOI":"10.5694\/j.1326-5377.1949.tb36912.x","article-title":"Lithium salts in the treatment of psychotic excitement","volume":"2","author":"Cade","year":"1949","journal-title":"Med. J. Aust."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib63","doi-asserted-by":"crossref","first-page":"79","DOI":"10.4088\/JCP.v60n0203","article-title":"A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group","volume":"60","author":"Calabrese","year":"1999","journal-title":"J. Clin. Psychiatry"},{"issue":"Suppl. 4","key":"10.1016\/j.brainresrev.2009.06.003_bib64","doi-asserted-by":"crossref","first-page":"S109","DOI":"10.1016\/S0924-977X(99)00023-1","article-title":"Controlled trials in bipolar I depression: focus on switch rates and efficacy","volume":"9","author":"Calabrese","year":"1999","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib65","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.mcn.2007.02.019","article-title":"BDNF regulates the expression and traffic of NMDA receptors in cultured hippocampal neurons","volume":"35","author":"Caldeira","year":"2007","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib66","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s00228-003-0670-7","article-title":"Comparison of lithium concentrations in red blood cells and plasma in samples collected for TDM, acute toxicity, or acute-on-chronic toxicity","volume":"59","author":"Camus","year":"2003","journal-title":"Eur. J. Clin. Pharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib67","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1001\/archpsyc.56.2.162","article-title":"Heritability estimates for psychotic disorders: the Maudsley twin psychosis series","volume":"56","author":"Cardno","year":"1999","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib68","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0304-3940(96)13264-X","article-title":"Lithium decreases turnover of arachidonate in several brain phospholipids","volume":"220","author":"Chang","year":"1996","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib69","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1023\/A:1020989701330","article-title":"Dynamics of docosahexaenoic acid metabolism in the central nervous system: lack of effect of chronic lithium treatment","volume":"24","author":"Chang","year":"1999","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib70","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1046\/j.1471-4159.2001.00311.x","article-title":"Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: a possible common effect of mood stabilizers","volume":"77","author":"Chang","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib71","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1007\/s11064-008-9731-8","article-title":"Chronic NMDA administration increases neuroinflammatory markers in rat frontal cortex: cross-talk between excitotoxicity and neuroinflammation","volume":"33","author":"Chang","year":"2008","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib72","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1007\/s11064-008-9817-3","article-title":"Chronic administration of mood stabilizers upregulates BDNF and bcl-2 expression levels in rat frontal cortex","volume":"34","author":"Chang","year":"2009","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib73","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.prostaglandins.2005.07.001","article-title":"Lipid signaling: sleep, synaptic plasticity, and neuroprotection","volume":"77","author":"Chen","year":"2005","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib74","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0893-133X(96)00239-4","article-title":"Increase in AP-1 transcription factor DNA binding activity by valproic acid","volume":"16","author":"Chen","year":"1997","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib75","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1046\/j.1471-4159.2000.0721327.x","article-title":"The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3","volume":"72","author":"Chen","year":"1999","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib76","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1017\/S1461145705005717","article-title":"Altered gene expression in mice treated with the mood stabilizer sodium valproate","volume":"9","author":"Chetcuti","year":"2006","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib77","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1615\/CritRevNeurobiol.v16.i12.90","article-title":"Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases?","volume":"16","author":"Chuang","year":"2004","journal-title":"Crit. Rev. Neurobiol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib78","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1196\/annals.1344.018","article-title":"The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials","volume":"1053","author":"Chuang","year":"2005","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib79","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/0092-8674(91)90556-E","article-title":"A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP","volume":"65","author":"Clark","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib80","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1097\/00041433-200206000-00006","article-title":"Recent studies on interactions between n\u22123 and n\u22126 polyunsaturated fatty acids in brain and other tissues","volume":"13","author":"Contreras","year":"2002","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib81","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1046\/j.1471-4159.2001.00658.x","article-title":"Chronic nutritional deprivation of n\u22123 alpha-linolenic acid does not affect n\u22126 arachidonic acid recycling within brain phospholipids of awake rats","volume":"79","author":"Contreras","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib82","series-title":"The Biochemical Basis of Neuropharmacology","author":"Cooper","year":"2003"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib83","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1097\/01.wnr.0000239957.53072.f0","article-title":"Cortical sulci and bipolar disorder","volume":"17","author":"Coyle","year":"2006","journal-title":"NeuroReport"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib84","article-title":"Strong genetic evidence for a selective influence of GABA(A) receptors on a component of the bipolar disorder phenotype","author":"Craddock","year":"2008","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib85","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1176\/ajp.2007.164.1.13","article-title":"How and why genetic linkage has not solved the problem of psychosis: review and hypothesis","volume":"164","author":"Crow","year":"2007","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib86","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/YCO.0b013e3280117733","article-title":"Animal models of mood disorders: recent developments","volume":"20","author":"Cryan","year":"2007","journal-title":"Curr. Opin. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib87","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0024-3205(00)00969-3","article-title":"Chronic pharmacological treatment with certain antidepressants alters the expression and DNA-binding activity of transcription factor AP-2","volume":"68","author":"Damberg","year":"2000","journal-title":"Life Sci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib88","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/BF00503818","article-title":"Cerebral pharmacokinetics of imipramine in rats after single and multiple dosages","volume":"317","author":"Daniel","year":"1981","journal-title":"Naunyn-Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib89","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1001\/archpsyc.1978.01770250121012","article-title":"Physostigmine in mania","volume":"35","author":"Davis","year":"1978","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib90","first-page":"217","article-title":"Regionally specific changes in levels of cortical S100beta in bipolar 1 disorder but not schizophrenia","volume":"40","author":"Dean","year":"2006","journal-title":"Aust. N. Z. J. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib91","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1111\/j.1471-4159.1991.tb02603.x","article-title":"Arecoline-stimulated brain incorporation of intravenously administered fatty acids in unanesthetized rats","volume":"56","author":"DeGeorge","year":"1991","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib92","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1093\/schbul\/sbm164","article-title":"The concept of progressive brain change in schizophrenia: implications for understanding schizophrenia","volume":"34","author":"DeLisi","year":"2008","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib93","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1111\/j.1471-4159.2005.03258.x","article-title":"alpha-Linolenic acid does not contribute appreciably to docosahexaenoic acid within brain phospholipids of adult rats fed a diet enriched in docosahexaenoic acid","volume":"94","author":"Demar","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib94","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.bbalip.2006.06.006","article-title":"Brain elongation of linoleic acid is a negligible source of the arachidonate in brain phospholipids of adult rats","volume":"1761","author":"DeMar","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib95","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1194\/jlr.M500362-JLR200","article-title":"One generation of n\u22123 polyunsaturated fatty acid deprivation increases depression and aggression test scores in rats","volume":"47","author":"DeMar","year":"2006","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib96","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.mcn.2006.01.015","article-title":"The common inositol-reversible effect of mood stabilizers on neurons does not involve GSK3 inhibition, myo-inositol-1-phosphate synthase or the sodium-dependent myo-inositol transporters","author":"Di Daniel","year":"2006","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib97","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1097\/01.ypg.0000218615.19892.86","article-title":"Lack of genetic association between the phospholipase A2 gene and bipolar mood disorder in a European multicentre case-control study","volume":"16","author":"Dikeos","year":"2006","journal-title":"Psychiatr. Genet."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib98","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1749-6632.1988.tb21627.x","article-title":"Interleukin-1","volume":"546","author":"Dinarello","year":"1988","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib99","series-title":"Antiepileptic drugs","first-page":"727","article-title":"Topiramate \u2014 chemistry, biotransformation and pharmacokinetics","author":"Doose","year":"2002"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib100","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1046\/j.1528-1157.2003.64402.x","article-title":"Topiramate and lamotrigine pharmacokinetics during repetitive monotherapy and combination therapy in epilepsy patients","volume":"44","author":"Doose","year":"2003","journal-title":"Epilepsia"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib101","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1038\/sj.npp.1300710","article-title":"The influence of chronic exposure to antipsychotic medications on brain size before and after tissue fixation: a comparison of haloperidol and olanzapine in macaque monkeys","volume":"30","author":"Dorph-Petersen","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib102","series-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"1994"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib103","doi-asserted-by":"crossref","first-page":"6578","DOI":"10.1523\/JNEUROSCI.1258-04.2004","article-title":"Modulation of synaptic plasticity by antimanic agents: the role of AMPA glutamate receptor subunit 1 synaptic expression","volume":"24","author":"Du","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib104","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/sj.npp.1301178","article-title":"The anticonvulsants lamotrigine, riluzole, and valproate differentially regulate AMPA receptor membrane localization: relationship to clinical effects in mood disorders","volume":"32","author":"Du","year":"2007","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib105","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/S0028-3908(99)00009-X","article-title":"Effects of repeated fluoxetine on anxiety-related behaviours, central serotonergic systems, and the corticotropic axis in SHR and WKY rats","volume":"38","author":"Durand","year":"1999","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib106","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/j.1399-5618.2006.00303.x","article-title":"Inositol augmentation of lithium or valproate for bipolar depression","volume":"8","author":"Eden Evins","year":"2006","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib107","doi-asserted-by":"crossref","first-page":"442","DOI":"10.2165\/00003088-199529060-00005","article-title":"Therapeutic drug monitoring for the treatment of psychiatric disorders. Clinical use and cost effectiveness","volume":"29","author":"Eilers","year":"1995","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib108","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.biopsych.2006.03.022","article-title":"Chronic treatment with mood stabilizers increases membrane GRK3 in rat frontal cortex","volume":"61","author":"Ertley","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib109","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1016\/j.neuroimage.2006.11.018","article-title":"Imaging signal transduction via arachidonic acid in the human brain during visual stimulation, by means of positron emission tomography","volume":"34","author":"Esposito","year":"2007","journal-title":"NeuroImage"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib110","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.2967\/jnumed.107.049619","article-title":"Imaging neuroinflammation in Alzheimer's disease with radiolabeled arachidonic acid and PET","volume":"49","author":"Esposito","year":"2008","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib111","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.biopsych.2005.05.001","article-title":"Mood disorders in the medically ill: scientific review and recommendations","volume":"58","author":"Evans","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib112","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1469-1809.1967.tb02015.x","article-title":"The inheritance of liability to diseases with variable age of onset, with particular reference to diabetes mellitus","volume":"31","author":"Falconer","year":"1967","journal-title":"Ann. Hum. Genet."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib113","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1038\/sj.mp.4001087","article-title":"Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity","volume":"7","author":"Farber","year":"2002","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib114","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1124\/pr.58.3.7","article-title":"Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders","volume":"58","author":"Farooqui","year":"2006","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib115","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/j.1471-4159.2006.04371.x","article-title":"Modulation of inflammation in brain: a matter of fat","volume":"101","author":"Farooqui","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib116","unstructured":"FDA, 2009. FDA approved drug products. In: http:\/\/www.accessdata.fda.gov\/scripts\/cder\/drugsatfda\/index.cfm, Accessed May 27."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib117","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1073\/pnas.87.6.2187","article-title":"Serotonin stimulates phospholipase A2 and the release of arachidonic acid in hippocampal neurons by a type 2 serotonin receptor that is independent of inositolphospholipid hydrolysis","volume":"87","author":"Felder","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib118","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0163-8343(91)90041-T","article-title":"Mania precipitated by prednisone and bromocriptine","volume":"13","author":"Fisher","year":"1991","journal-title":"Gen. Hosp. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib119","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1172\/JCI13241","article-title":"Regulated formation of eicosanoids","volume":"107","author":"Fitzpatrick","year":"2001","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jad.2005.01.004","article-title":"Treatment guidelines for bipolar disorder: a critical review","volume":"86","author":"Fountoulakis","year":"2005","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib121","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jad.2007.10.016","article-title":"Treatment of bipolar depression: an update","volume":"109","author":"Fountoulakis","year":"2008","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib122","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1192\/bjp.188.1.46","article-title":"Efficacy of ethyl-eicosapentaenoic acid in bipolar depression: randomised double-blind placebo-controlled study","volume":"188","author":"Frangou","year":"2006","journal-title":"Br. J. Psychiatry."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib123","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0278-5846(98)00040-2","article-title":"Effect of chronic antidepressant treatment on transcription factor binding activity in rat hippocampus and frontal cortex","volume":"22","author":"Frechilla","year":"1998","journal-title":"Prog. Neuro-psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib124","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1089\/089771503322584628","article-title":"Apoptosis of spinal cord neurons by preventing depletion nicotine attenuates arachidonic acid-induced of neurotrophic factors","volume":"20","author":"Garrido","year":"2003","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib125","doi-asserted-by":"crossref","first-page":"35018","DOI":"10.1074\/jbc.M504108200","article-title":"Transcription of the NR1 subunit of the N-methyl-d-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia","volume":"280","author":"Gascon","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib126","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1074\/jbc.M304777200","article-title":"The caveolin scaffolding domain modifies 2-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor binding properties by inhibiting phospholipase A2 activity","volume":"279","author":"Gaudreault","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib127","first-page":"22","article-title":"A cross-sectional study of parkinsonism and tardive dyskinesia in lithium-treated affective disordered patients","volume":"57","author":"Ghadirian","year":"1996","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib128","unstructured":"Ghaemi, N., 2001. Bipolar Disorder. http:\/\/www.familyaware.org\/expertprofiles\/drghaemi4.asp#diagnosed."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib129","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1176\/appi.ajp.161.1.163","article-title":"Antidepressant treatment in bipolar versus unipolar depression","volume":"161","author":"Ghaemi","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib130","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.biopsych.2004.05.012","article-title":"Chronic carbamazepine selectively downregulates cytosolic phospholipase A2 expression and cyclooxygenase activity in rat brain","volume":"56","author":"Ghelardoni","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib131","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s00213-005-2189-3","article-title":"Topiramate does not alter expression in rat brain of enzymes of arachidonic acid metabolism","volume":"180","author":"Ghelardoni","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib132","first-page":"1471","article-title":"Brain incorporation of [11C]arachidonic acid, blood volume, and blood flow in healthy aging: a study with partial-volume correction","volume":"45","author":"Giovacchini","year":"2004","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib134","series-title":"Manic-depressive Illness: Bipolar Disorders and Recurrent Depression","author":"Goodwin","year":"2007"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib135","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1038\/sj.npp.1300731","article-title":"Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs","volume":"30","author":"Gould","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib136","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/sj.npp.1300283","article-title":"In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3","volume":"29","author":"Gould","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib137","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1038\/sj.mp.4001518","article-title":"Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers","volume":"9","author":"Gould","year":"2004","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib138","doi-asserted-by":"crossref","unstructured":"Greenwood, T.A., Schork, N.J., Eskin, E., Kelsoe, J.R., 2006. Identification of additional variants within the human dopamine transporter gene provides further evidence for an association with bipolar disorder in two independent samples. Mol. Psychiatry 11, 125\u2013133, 115.","DOI":"10.1038\/sj.mp.4001764"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib139","doi-asserted-by":"crossref","first-page":"942","DOI":"10.4088\/JCP.v63n1013","article-title":"Is response to prophylactic lithium a familial trait?","volume":"63","author":"Grof","year":"2002","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib140","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0014-5793(03)00167-4","article-title":"Lithium-induced inhibition of Src tyrosine kinase in rat cerebral cortical neurons: a role in neuroprotection against N-methyl-d-aspartate receptor-mediated excitotoxicity","volume":"538","author":"Hashimoto","year":"2003","journal-title":"FEBS Lett."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib141","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0920-1211(00)00196-0","article-title":"Chronic lamotrigine treatment increases rat hippocampal GABA shunt activity and elevates cerebral taurine levels","volume":"43","author":"Hassel","year":"2001","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib142","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1016\/S0022-3565(24)38853-6","article-title":"Selective dopamine receptor stimulation differentially affects [3H]arachidonic acid incorporation, a surrogate marker for phospholipase A2-mediated neurotransmitter signal transduction, in a rodent model of Parkinson's disease","volume":"296","author":"Hayakawa","year":"2001","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib143","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/0006-3223(90)90449-C","article-title":"Effects of lithium on auditory evoked potentials in healthy subjects","volume":"27","author":"Hegerl","year":"1990","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib144","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0079-6123(08)62413-9","article-title":"The phosphoinositide signaling system. I. Historical background. II. Effects of lithium on the accumulation of second messenger inositol 1,4,5-trisphosphate in brain cortex slices","volume":"98","author":"Hokin","year":"1993","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib145","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1080\/07315724.1986.10720125","article-title":"Control of polyunsaturated acids in tissue lipids","volume":"5","author":"Holman","year":"1986","journal-title":"J. Am. Coll. Nutr."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib146","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1038\/sj.mp.4001730","article-title":"A dopamine transporter mutation associated with bipolar affective disorder causes inhibition of transporter cell surface expression","volume":"10","author":"Horschitz","year":"2005","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib147","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.coph.2006.09.004","article-title":"Prostaglandins and adenosine in the regulation of sleep and wakefulness","volume":"7","author":"Huang","year":"2007","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib148","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1194\/jlr.M700315-JLR200","article-title":"Dietary n\u22123 PUFA deprivation for 15 weeks upregulates elongase and desaturase expression in rat liver but not brain","volume":"48","author":"Igarashi","year":"2007","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib151","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0028-3908(02)00334-9","article-title":"Role of AMPA and NMDA receptors in the nucleus accumbens shell in turning behaviour of rats: interaction with dopamine receptors","volume":"44","author":"Ikeda","year":"2003","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib152","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1023\/A:1027393724676","article-title":"Membrane fatty acid modifications of PC12 cells by arachidonate or docosahexaenoate affect neurite outgrowth but not norepinephrine release","volume":"22","author":"Ikemoto","year":"1997","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib153","first-page":"229","article-title":"Low-dose valproate: a new treatment for cyclothymia, mild rapid cycling disorders, and premenstrual syndrome","volume":"54","author":"Jacobsen","year":"1993","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib154","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/sj.mp.4000476","article-title":"Mutational analysis of phospholipase A2A: a positional candidate susceptibility gene for bipolar disorder","volume":"4","author":"Jacobsen","year":"1999","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib155","series-title":"Psychopharmacology. The Fourth Generation of Progress","first-page":"945","article-title":"The role of acetylcholine mechanisms in mood disorders","author":"Janowsky","year":"1995"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib156","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1046\/j.1471-4159.1996.67020822.x","article-title":"Preferential in vivo incorporation of [3H]arachidonic acid from blood into rat brain synaptosomal fractions before and after cholinergic stimulation","volume":"67","author":"Jones","year":"1996","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib157","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0165-6147(03)00206-2","article-title":"Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes","volume":"24","author":"Jope","year":"2003","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib158","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1001\/archpsyc.1977.01770150104012","article-title":"The effect of lithium carbonate on affect, mood, and personality of normal subjects","volume":"34","author":"Judd","year":"1977","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib159","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1001\/archpsyc.1977.01770150113013","article-title":"The effect of lithium carbonate on the cognitive functions of normal subjects","volume":"34","author":"Judd","year":"1977","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib160","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1001\/archpsyc.59.6.530","article-title":"The long-term natural history of the weekly symptomatic status of bipolar I disorder","volume":"59","author":"Judd","year":"2002","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib161","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0165-0327(02)00332-4","article-title":"The prevalence and disability of bipolar spectrum disorders in the US population: re-analysis of the ECA database taking into account subthreshold cases","volume":"73","author":"Judd","year":"2003","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib162","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1146\/annurev.med.52.1.503","article-title":"Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia","volume":"52","author":"Kapur","year":"2001","journal-title":"Annu. Rev. Med."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib163","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1440-1819.2007.01604.x","article-title":"Molecular genetics of bipolar disorder and depression","volume":"61","author":"Kato","year":"2007","journal-title":"Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib164","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.neubiorev.2007.03.003","article-title":"Animal models of bipolar disorder","volume":"31","author":"Kato","year":"2007","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib165","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1073\/pnas.93.6.2317","article-title":"COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex","volume":"93","author":"Kaufmann","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib166","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/j.biopsych.2006.03.056","article-title":"Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder","volume":"60","author":"Keck","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib167","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0165-0327(98)00126-8","article-title":"The effect of the first manic episode in affective disorder: a case register study of hospitalised episodes","volume":"53","author":"Kessing","year":"1999","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib168","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0006-3223(00)00975-6","article-title":"Effects of mood and subtype on cerebral glucose metabolism in treatment-resistant bipolar disorder","volume":"49","author":"Ketter","year":"2001","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib169","series-title":"Treatment of acute mania in bipolar disorder","year":"2005"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib170","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0022-3999(95)00524-2","article-title":"Is aspirin, as used for antithrombosis, an emotion-modulating agent?","volume":"40","author":"Ketterer","year":"1996","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib171","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1176\/ajp.161.10.1814","article-title":"High concordance of bipolar I disorder in a nationwide sample of twins","volume":"161","author":"Kieseppa","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib173","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jad.2007.02.018","article-title":"Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder","volume":"104","author":"Kim","year":"2007","journal-title":"J. Affect. Disord."},{"issue":"Suppl. 1","key":"10.1016\/j.brainresrev.2009.06.003_bib175","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1159\/000054844","article-title":"Differential efficacy of lithium and carbamazepine in the prophylaxis of bipolar disorder: results of the MAP study","volume":"42","author":"Kleindienst","year":"2000","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib176","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0163-7258(92)90037-Z","article-title":"Rhythms and the pharmacology of lithium","volume":"56","author":"Klemfuss","year":"1992","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib177","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.biopsych.2007.08.018","article-title":"Effect of chronic antipsychotic exposure on astrocyte and oligodendrocyte numbers in macaque monkeys","volume":"63","author":"Konopaske","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib178","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1399-5618.2006.00276.x","article-title":"Topiramate monotherapy in the management of acute mania: results of four double-blind placebo-controlled trials","volume":"8","author":"Kushner","year":"2006","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib179","first-page":"363","article-title":"Fatty acid composition in postmortem brains of people who completed suicide","volume":"32","author":"Lalovic","year":"2007","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib180","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/ajmg.b.30104","article-title":"Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders","volume":"133","author":"Lasky-Su","year":"2005","journal-title":"Am. J. Med. Genet., B Neuropsychiatr. Genet."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib181","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1172\/JCI11003","article-title":"Brain tissue responses to ischemia","volume":"106","author":"Lee","year":"2000","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib182","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/j.1471-4159.2004.02786.x","article-title":"In vivo imaging detects a transient increase in brain arachidonic acid metabolism: a potential marker of neuroinflammation","volume":"91","author":"Lee","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib183","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s00213-007-0803-2","article-title":"Chronic lamotrigine does not alter the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat: implications for the treatment of bipolar disorder","volume":"193","author":"Lee","year":"2007","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib184","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00213-006-0582-1","article-title":"Chronic fluoxetine increases cytosolic phospholipase A(2) activity and arachidonic acid turnover in brain phospholipids of the unanesthetized rat","volume":"190","author":"Lee","year":"2007","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib185","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1007\/s11064-007-9526-3","article-title":"Chronic administration of lamotrigine downregulates COX-2 mRNA and protein in rat frontal cortex","volume":"33","author":"Lee","year":"2008","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib186","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1194\/jlr.M700406-JLR200","article-title":"Chronic N-methyl-d-aspartate administration increases the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat","volume":"49","author":"Lee","year":"2008","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib187","article-title":"Chronic imipramine but not bupropion increases arachidonic acid signaling in rat brain: is this related to \u2018switching\u2019 in bipolar disorder?","author":"Lee","year":"2008","journal-title":"Mol. Psychiatry."},{"issue":"Suppl. 9","key":"10.1016\/j.brainresrev.2009.06.003_bib188","first-page":"5","article-title":"Overview of the mechanism of action of lithium in the brain","volume":"61","author":"Lenox","year":"2000","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib189","first-page":"89","article-title":"Carbamazepine versus lithium in mania: a double-blind study","volume":"48","author":"Lerer","year":"1987","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib190","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1176\/appi.ajp.163.2.232","article-title":"Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood stabilizers","volume":"163","author":"Leverich","year":"2006","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib191","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0165-0327(00)00361-X","article-title":"Synaptic, intracellular, and neuroprotective mechanisms of anticonvulsants: are they relevant for the treatment and course of bipolar disorders?","volume":"69","author":"Li","year":"2002","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib192","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1586\/14737175.4.5.759","article-title":"Use of olanzapine in the treatment of bipolar I disorder","volume":"4","author":"Lieberman","year":"2004","journal-title":"Expert Rev. Neurotherapeutics"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib193","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1124\/pr.107.00107","article-title":"Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection","volume":"60","author":"Lieberman","year":"2008","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib194","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.neuron.2006.10.011","article-title":"Modulation of D2R-NR2B interactions in response to cocaine","volume":"52","author":"Liu","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib195","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.brainres.2004.03.018","article-title":"Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt\/PKB, ERK1\/2, and the mitogen-activated protein kinase p38","volume":"1011","author":"Lu","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib196","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1006\/bbrc.2000.3173","article-title":"Activation of ERK1\/2 and cPLA(2) by the p55 TNF receptor occurs independently of FAN","volume":"274","author":"Luschen","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib197","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1399-5618.2006.00284.x","article-title":"Regional cerebral cortical thinning in bipolar disorder","volume":"8","author":"Lyoo","year":"2006","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib198","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.brainres.2006.05.048","article-title":"Cytosolic prostaglandin E(2) synthase (cPGES) expression is decreased in discrete cortical regions in psychiatric disease","volume":"1103","author":"Maida","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib199","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/S0006-3223(00)00929-X","article-title":"Signaling: cellular insights into the pathophysiology of bipolar disorder","volume":"48","author":"Manji","year":"2000","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib200","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/BF03033368","article-title":"Antipsychotic-induced oxidative stress in rat brain","volume":"13","author":"Martins","year":"2008","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib201","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.schres.2006.02.001","article-title":"N-methyl-d-aspartate receptor NR2B subunit gene GRIN2B in schizophrenia and bipolar disorder: polymorphisms and mRNA levels","volume":"84","author":"Martucci","year":"2006","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib202","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/ajmg.10118","article-title":"Positive association of dopamine D2 receptor polymorphism with bipolar affective disorder in a European Multicenter Association Study of affective disorders","volume":"114","author":"Massat","year":"2002","journal-title":"Am. J. Med. Genet."},{"issue":"Pt. 2","key":"10.1016\/j.brainresrev.2009.06.003_bib203","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1042\/bj3180701","article-title":"Release of secretory phospholipase A2 from rat neuronal cells and its possible function in the regulation of catecholamine secretion","volume":"318","author":"Matsuzawa","year":"1996","journal-title":"Biochem. J."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib204","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1176\/appi.ajp.163.3.478","article-title":"Regional brain morphometry in patients with schizophrenia or bipolar disorder and their unaffected relatives","volume":"163","author":"McDonald","year":"2006","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib205","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0306-4522(97)00116-4","article-title":"The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed","volume":"81","author":"McGahon","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib206","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1001\/archpsyc.60.5.497","article-title":"The heritability of bipolar affective disorder and the genetic relationship to unipolar depression","volume":"60","author":"McGuffin","year":"2003","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib207","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.psychres.2007.08.021","article-title":"Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder","volume":"160","author":"McNamara","year":"2008","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib208","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1097\/FPC.0b013e328011b5b2","article-title":"A microarray gene expression study of the molecular pharmacology of lithium carbonate on mouse brain mRNA to understand the neurobiology of mood stabilization and treatment of bipolar affective disorder","volume":"17","author":"McQuillin","year":"2007","journal-title":"Pharmacogenet. Genomics"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib209","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1034\/j.1399-5618.2003.00025.x","article-title":"Allelic association study between phospholipase A2 genes and bipolar affective disorder","volume":"5","author":"Meira-Lima","year":"2003","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib210","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1007\/s00213-003-1440-z","article-title":"Acute mania is accompanied by elevated glutamate\/glutamine levels within the left dorsolateral prefrontal cortex","volume":"168","author":"Michael","year":"2003","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib211","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1111\/j.1471-4159.2005.03654.x","article-title":"The interaction between dopamine D2-like and beta-adrenergic receptors in the prefrontal cortex is altered by mood-stabilizing agents","volume":"96","author":"Montezinho","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib212","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/nrn2284","article-title":"Targeting the murine serotonin transporter: insights into human neurobiology","volume":"9","author":"Murphy","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib213","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1001\/archpsyc.59.2.115","article-title":"Revised prevalence estimates of mental disorders in the United States: using a clinical significance criterion to reconcile 2 surveys' estimates","volume":"59","author":"Narrow","year":"2002","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib214","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.schres.2007.09.015","article-title":"Regional thinning of the cerebral cortex in schizophrenia: effects of diagnosis, age and antipsychotic medication","volume":"98","author":"Nesvag","year":"2008","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib215","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1046\/j.1471-4159.1997.69020704.x","article-title":"Metabotropic glutamate receptor subtype mGluR1\u03b1 stimulates the secretion of the amyloid beta-protein precursor ectodomain","volume":"69","author":"Nitsch","year":"1997","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib216","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1176\/appi.ajp.160.12.2222","article-title":"Cross-national comparisons of seafood consumption and rates of bipolar disorders","volume":"160","author":"Noaghiul","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib217","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/0006-3223(93)90157-9","article-title":"Elevated PLA2 activity in schizophrenics and other psychiatric patients","volume":"34","author":"Noponen","year":"1993","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib218","doi-asserted-by":"crossref","first-page":"4073","DOI":"10.1210\/endo.139.10.6225","article-title":"Mass spectrometric evidence that agents that cause loss of Ca2+ from intracellular compartments induce hydrolysis of arachidonic acid from pancreatic islet membrane phospholipids by a mechanism that does not require a rise in cytosolic Ca2+ concentration","volume":"139","author":"Nowatzke","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib219","first-page":"391","article-title":"Distribution of cytoplasmic phospholipase A2 in the normal rat brain","volume":"39","author":"Ong","year":"1999","journal-title":"J. Hirnforsch."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib220","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s11068-006-8730-4","article-title":"Distribution of calcium-independent phospholipase A2 (iPLA2) in monkey brain","volume":"34","author":"Ong","year":"2005","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib221","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/0014-4886(91)90103-J","article-title":"Analysis of the convulsant-potentiating effects of lithium in rats","volume":"111","author":"Ormandy","year":"1991","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib222","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.psc.2005.02.005","article-title":"Cognition in bipolar disorder","volume":"28","author":"Osuji","year":"2005","journal-title":"Psychiatr. Clin. North Am."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib223","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1046\/j.1471-4159.1997.69062336.x","article-title":"Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain","volume":"69","author":"Ozaki","year":"1997","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib224","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1159\/000077364","article-title":"BanI polymorphism of the cytosolic phospholipase A2 gene and mood disorders in the Korean population","volume":"49","author":"Pae","year":"2004","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib225","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1074\/jbc.274.2.628","article-title":"Evidence for a beta2-adrenergic\/arachidonic acid pathway in ventricular cardiomyocytes. Regulation by the beta1-adrenergic\/camp pathway","volume":"274","author":"Pavoine","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib226","doi-asserted-by":"crossref","first-page":"146","DOI":"10.2165\/00002018-199512020-00007","article-title":"Drug-induced mania","volume":"12","author":"Peet","year":"1995","journal-title":"Drug Safety"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib227","doi-asserted-by":"crossref","first-page":"36734","DOI":"10.1074\/jbc.M101287200","article-title":"Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen","volume":"276","author":"Phiel","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib228","series-title":"Psychopharmacology: The Fourth Generation of Progress","first-page":"595","article-title":"Arachidonic acid","author":"Piomelli","year":"1995"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib229","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1055\/s-2007-1014476","article-title":"Sensitization and kindling perspectives for the course of affective illness: toward a new treatment with the anticonvulsant carbamazepine","volume":"23","author":"Post","year":"1990","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib230","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1586\/14737175.4.6.S27","article-title":"Bipolar depression: the role of atypical antipsychotics","volume":"4","author":"Post","year":"2004","journal-title":"Expert Rev. Neurotherapeutics"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib231","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/BF00431272","article-title":"Dopamine and mania: behavioral and biochemical effects of the dopamine receptor blocker pimozide","volume":"67","author":"Post","year":"1980","journal-title":"Psychopharmacology (Berl)"},{"issue":"Suppl. 11","key":"10.1016\/j.brainresrev.2009.06.003_bib232","first-page":"153","article-title":"Rational polypharmacy in the bipolar affective disorders","author":"Post","year":"1996","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib233","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1192\/bjp.bp.105.013045","article-title":"Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline","volume":"189","author":"Post","year":"2006","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib234","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/jcp.10175","article-title":"Mechanisms regulating the expression, self-maintenance, and signaling-function of the bradykinin B2 and B1 receptors","volume":"193","author":"Prado","year":"2002","journal-title":"J. Cell. Physiol."},{"issue":"Pt. 2","key":"10.1016\/j.brainresrev.2009.06.003_bib235","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1042\/bj3350313","article-title":"Energy requirements for two aspects of phospholipid metabolism in mammalian brain","volume":"335","author":"Purdon","year":"1998","journal-title":"Biochem. J."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib236","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1111\/j.1471-4159.2005.03464.x","article-title":"Role of AP-1 in ethanol-induced N-methyl-d-aspartate receptor 2B subunit gene up-regulation in mouse cortical neurons","volume":"95","author":"Qiang","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib237","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/sj.npp.1300022","article-title":"Imaging brain phospholipase A2 activation in awake rat in response to 5-HT2A\/2C agonist, (+\/\u2212)-2,5-dimethoxy-4-iodophenyl-2-aminopropane (DOI)","volume":"28","author":"Qu","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib238","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1046\/j.1471-4159.1998.70010325.x","article-title":"Selective acceleration of arachidonic acid reincorporation into brain membrane phospholipid following transient ischemia in awake gerbil","volume":"70","author":"Rabin","year":"1998","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib239","doi-asserted-by":"crossref","first-page":"10237","DOI":"10.1073\/pnas.172399499","article-title":"Appraising the brain's energy budget","volume":"99","author":"Raichle","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib240","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1038\/sj.npp.1300740","article-title":"Decrease in the AP-2 DNA-binding activity and in the protein expression of AP-2 alpha and AP-2 beta in frontal cortex of rats treated with lithium for 6 weeks","volume":"30","author":"Rao","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib241","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/sj.tpj.6500391","article-title":"Chronic fluoxetine upregulates activity, protein and mRNA levels of cytosolic phospholipase A2 in rat frontal cortex","volume":"6","author":"Rao","year":"2006","journal-title":"Pharmacogenomics J."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib242","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/j.1399-5618.2007.00361.x","article-title":"Chronic treatment of rats with sodium valproate downregulates frontal cortex NF-kappaB DNA binding activity and COX-2 mRNA","volume":"9","author":"Rao","year":"2007","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib243","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.biopsych.2006.03.029","article-title":"Chronic administration of carbamazepine down-regulates AP-2 DNA-binding activity and AP-2\u03b1 protein expression in rat frontal cortex","volume":"61","author":"Rao","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib244","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/sj.mp.4001887","article-title":"Dietary n\u22123 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex","volume":"12","author":"Rao","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib245","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/sj.mp.4001888","article-title":"n\u22123 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism","volume":"12","author":"Rao","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib246","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1111\/j.1471-4159.2007.04648.x","article-title":"Chronic NMDA administration to rats up-regulates frontal cortex cytosolic phospholipase A2 and its transcription factor, activator protein-2","volume":"102","author":"Rao","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib247","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/mp.2008.31","article-title":"Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?","volume":"13","author":"Rao","year":"2008","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib248","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1017\/S146114570900025X","article-title":"Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients","volume":"12","author":"Rao","year":"2009","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib249","doi-asserted-by":"crossref","unstructured":"Rao, J.S., Rapoport, S.I., Kim, H.W., 2009b. Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients. Mol Psychiatry. (Electronic publication ahead of print).","DOI":"10.1038\/mp.2009.47"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib250","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1385\/JMN:16:2-3:243","article-title":"In vivo fatty acid incorporation into brain phospholipids in relation to plasma availability, signal transduction and membrane remodeling","volume":"16","author":"Rapoport","year":"2001","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib251","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1067\/S0022-3476(03)00399-8","article-title":"In vivo approaches to quantifying and imaging brain arachidonic and docosahexaenoic acid metabolism","volume":"143","author":"Rapoport","year":"2003","journal-title":"J. Pediatr."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib252","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1001\/archpsyc.59.7.592","article-title":"Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder?","volume":"59","author":"Rapoport","year":"2002","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib253","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/S0022-2275(20)31629-1","article-title":"Delivery and turnover of plasma-derived essential PUFAs in mammalian brain","volume":"42","author":"Rapoport","year":"2001","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib254","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.plefa.2007.10.023","article-title":"Brain metabolism of nutritionally essential polyunsaturated fatty acids depends on both the diet and the liver","volume":"77","author":"Rapoport","year":"2007","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib255","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/01.fbp.0000179278.03868.96","article-title":"Chronic intracerebroventricular infusion of lipopolysaccharide: effects of ibuprofen treatment and behavioural and histopathological correlates","volume":"16","author":"Richardson","year":"2005","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib256","doi-asserted-by":"crossref","first-page":"3887","DOI":"10.1097\/00001756-199912160-00030","article-title":"85\u00a0kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain","volume":"10","author":"Rintala","year":"1999","journal-title":"NeuroReport"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib257","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0165-0173(92)90016-F","article-title":"A quantitative method for measuring regional in vivo fatty-acid incorporation into and turnover within brain phospholipids: review and critical analysis","volume":"17","author":"Robinson","year":"1992","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib258","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbalip.2009.03.009","article-title":"Intracellular- and extracellular-derived Ca2+ influence phospholipase A(2)-mediated fatty acid release from brain phospholipids","author":"Rosa","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib259","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1046\/j.1471-4159.2003.02246.x","article-title":"Rat brain arachidonic acid metabolism is increased by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide","volume":"88","author":"Rosenberger","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib260","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1476-511X-6-21","article-title":"Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid?","volume":"6","author":"Ross","year":"2007","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib261","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.neubiorev.2007.03.002","article-title":"GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder","volume":"31","author":"Rowe","year":"2007","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib262","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/j.1399-5618.2005.00194.x","article-title":"GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid","volume":"7","author":"Ryves","year":"2005","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib263","doi-asserted-by":"crossref","first-page":"32S","DOI":"10.1097\/00004714-199604001-00005","article-title":"Bipolar mood disorder: practical strategies for acute and maintenance phase treatment","volume":"16","author":"Sachs","year":"1996","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib264","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1034\/j.1399-5618.2000.20306.x","article-title":"The treatment of bipolar depression","volume":"2","author":"Sachs","year":"2000","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib265","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1056\/NEJMoa064135","article-title":"Effectiveness of adjunctive antidepressant treatment for bipolar depression","volume":"356","author":"Sachs","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib266","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/sj.npp.1301575","article-title":"Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder","volume":"33","author":"Schloesser","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib267","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1086\/498619","article-title":"Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35\u2013p36 and provides further evidence of loci on chromosome 4q31 and 6q24","volume":"77","author":"Schumacher","year":"2005","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib268","doi-asserted-by":"crossref","first-page":"4266","DOI":"10.1021\/pr800188y","article-title":"High throughput lipidomic profiling of schizophrenia and bipolar disorder brain tissue reveals alterations of free fatty acids, phosphatidylcholines, and ceramides","volume":"7","author":"Schwarz","year":"2008","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib269","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0952-3278(97)90410-5","article-title":"Modulation of the expression of early genes by polyunsaturated fatty acids","volume":"57","author":"Sellmayer","year":"1997","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib270","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.atc.2006.01.003","article-title":"Novel chemical mediators in the resolution of inflammation: resolvins and protectins","volume":"24","author":"Serhan","year":"2006","journal-title":"Anesthesiol. Clin."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib271","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1471-4159.1990.tb08813.x","article-title":"Arachidonic acid cascade and signal transduction","volume":"55","author":"Shimizu","year":"1990","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib272","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0736-5748(00)00033-2","article-title":"Coupling of dopamine receptor subtypes to multiple and diverse G proteins","volume":"18","author":"Sidhu","year":"2000","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib273","first-page":"S235","article-title":"Atypical antipsychotics and the burden of disease","volume":"11","author":"Simpson","year":"2005","journal-title":"Am. J. Manag. Care"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib274","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/sj.mp.4002151","article-title":"Whole-genome association study of bipolar disorder","volume":"3","author":"Sklar","year":"2008","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib275","article-title":"Mood stabilizers and mood swings: in search of a definition","volume":"16","author":"Sobo","year":"1999","journal-title":"Psychiatric Times"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib276","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0014-2999(96)00265-8","article-title":"Lamotrigine inhibits Ca2+ currents in cortical neurons: functional implications","volume":"307","author":"Stefani","year":"1996","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib277","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.neuroimage.2006.03.014","article-title":"Modulatory role of cyclooxygenase-2 in cerebrovascular coupling","volume":"32","author":"Stefanovic","year":"2006","journal-title":"NeuroImage"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib279","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1001\/archpsyc.56.5.407","article-title":"Omega 3 fatty acids in bipolar disorder: a preliminary double-blind, placebo-controlled trial","volume":"56","author":"Stoll","year":"1999","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib280","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1176\/appi.ajp.159.11.1841","article-title":"Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder","volume":"159","author":"Strakowski","year":"2002","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib281","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1038\/sj.bjp.0705326","article-title":"Docosahexaenoic acid and arachidonic acid release in rat brain astrocytes is mediated by two separate isoforms of phospholipase A2 and is differently regulated by cyclic AMP and Ca2+","volume":"139","author":"Strokin","year":"2003","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib282","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/S0090-9556(25)08996-2","article-title":"Pharmacokinetics of bupropion and metabolites in plasma and brain of rats, mice, and guinea pigs","volume":"14","author":"Suckow","year":"1986","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib283","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF03259908","article-title":"Drug-induced mania\u2014causative agents, clinical characteristics and management. A retrospective analysis of the literature","volume":"4","author":"Sultzer","year":"1989","journal-title":"Med. Toxicol. Adverse Drug Exp."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib284","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1749-6632.1989.tb22597.x","article-title":"Deacylation\u2013reacylation of arachidonoyl groups in cerebral phospholipids","volume":"559","author":"Sun","year":"1989","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib285","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1385\/MN:31:1-3:027","article-title":"Phospholipase A2 in astrocytes: responses to oxidative stress, inflammation, and G protein-coupled receptor agonists","volume":"31","author":"Sun","year":"2005","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib286","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1001\/archpsyc.1997.01830130041008","article-title":"Depression during mania. Treatment response to lithium or divalproex","volume":"54","author":"Swann","year":"1997","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib287","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0090-6980(99)00033-7","article-title":"Cyclooxygenases-1 and 2 couple to cytosolic but not group IIA phospholipase A2 in COS-1 cells","volume":"60","author":"Takano","year":"2000","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib288","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0278-5846(01)00286-X","article-title":"The effects of antidepressant drug treatments on activator protein-1 binding activity in the rat brain","volume":"26","author":"Tamura","year":"2002","journal-title":"Prog. Neuro-psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib289","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1002\/(SICI)1097-4547(19990215)55:4<401::AID-JNR1>3.0.CO;2-H","article-title":"Regional localization of dopamine and ionotropic glutamate receptor subtypes in striatolimbic brain regions","volume":"55","author":"Tarazi","year":"1999","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib290","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/0888-7543(95)80093-2","article-title":"Cytosolic phospholipase A2 gene in human and rat: chromosomal localization and polymorphic markers","volume":"26","author":"Tay","year":"1995","journal-title":"Genomics"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib291","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1590\/S1516-44462006000300020","article-title":"Memantine may acutely improve cognition and have a mood stabilizing effect in treatment-resistant bipolar disorder","volume":"28","author":"Teng","year":"2006","journal-title":"Rev. Bras. Psiquiatr."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib292","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/sj.npp.1300039","article-title":"Differential effects of haloperidol, risperidone, and clozapine exposure on cholinergic markers and spatial learning performance in rats","volume":"28","author":"Terry","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib293","doi-asserted-by":"crossref","first-page":"5131","DOI":"10.1523\/JNEUROSCI.1021-04.2004","article-title":"Dopamine\u2013glutamate interactions controlling prefrontal cortical pyramidal cell excitability involve multiple signaling mechanisms","volume":"24","author":"Tseng","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib294","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0165-0327(90)90046-B","article-title":"Effect of lithium on the dynamics of electroencephalographic vigilance in healthy subjects","volume":"20","author":"Ulrich","year":"1990","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib295","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0893-133X(94)00088-H","article-title":"Myo-inositol monophosphatase: diverse effects of lithium, carbamazepine, and valproate","volume":"12","author":"Vadnal","year":"1995","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib296","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s002130000380","article-title":"Carbamazepine and valproate monotherapy: feasibility, relative safety and efficacy, and therapeutic drug monitoring in manic disorder","volume":"150","author":"Vasudev","year":"2000","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib297","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1046\/j.1471-4159.1995.64062765.x","article-title":"Dopamine D2 receptors potentiate arachidonate release via activation of cytosolic, arachidonate-specific phospholipase A2","volume":"64","author":"Vial","year":"1995","journal-title":"J. Neurochem."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib298","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0028-3908(98)00197-X","article-title":"Effects of lithium on receptor-mediated activation of G proteins in rat brain cortical membranes","volume":"38","author":"Wang","year":"1999","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib299","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.brainresbull.2004.04.005","article-title":"The effect of chronic lithium on arachidonic acid release and metabolism in rat brain does not involve secretory phospholipase A2 or lipoxygenase\/cytochrome P450 pathways","volume":"63","author":"Weerasinghe","year":"2004","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib300","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/s002109900131","article-title":"Bilobalide, a constituent of Ginkgo biloba, inhibits NMDA-induced phospholipase A2 activation and phospholipid breakdown in rat hippocampus","volume":"360","author":"Weichel","year":"1999","journal-title":"Naunyn-Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib301","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nature05911","article-title":"Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls","volume":"447","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.brainresrev.2009.06.003_bib302","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1002\/ajmg.b.30883","article-title":"Genome scan in sibling pairs with juvenile-onset mood disorders: evidence for linkage to 13q and Xq","volume":"150B","author":"Wigg","year":"2009","journal-title":"Am. J. Med. Genet., B Neuropsychiatr. Genet."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib303","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1080\/10408360701713112","article-title":"Relevant issues in the monitoring and the toxicology of antidepressants","volume":"45","author":"Wille","year":"2008","journal-title":"Crit. Rev. Clin. Lab. Sci."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib304","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/ajmg.b.20051","article-title":"Genome scan of the fifty-six bipolar pedigrees from the NIMH genetics initiative replication sample: chromosomes 4, 7, 9, 18, 19, 20, and 21","volume":"121B","author":"Willour","year":"2003","journal-title":"Am. J. Med. Genet., B Neuropsychiatr. Genet."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib305","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0006-8993(99)01997-6","article-title":"Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation","volume":"846","author":"Xiao","year":"1999","journal-title":"Brain Res."},{"issue":"Suppl. 4","key":"10.1016\/j.brainresrev.2009.06.003_bib306","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1399-5618.2005.00211.x","article-title":"Translating knowledge of genetics and pharmacology into improving everyday practice","volume":"7","author":"Yatham","year":"2005","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.brainresrev.2009.06.003_bib307","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.biopsych.2004.11.023","article-title":"An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression","volume":"57","author":"Zarate","year":"2005","journal-title":"Biol. Psychiatry"}],"container-title":["Brain Research Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165017309000745?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165017309000745?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T08:51:44Z","timestamp":1739177504000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165017309000745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":299,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S0165017309000745"],"URL":"https:\/\/doi.org\/10.1016\/j.brainresrev.2009.06.003","relation":{},"ISSN":["0165-0173"],"issn-type":[{"value":"0165-0173","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]}}}