{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:05:38Z","timestamp":1787731538100,"version":"build-2784847793"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/K50130X\/1"],"award-info":[{"award-number":["MR\/K50130X\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behaviour Research and Therapy"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.brat.2020.103760","type":"journal-article","created":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T20:38:24Z","timestamp":1603744704000},"page":"103760","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Training negative connectivity patterns between the dorsolateral prefrontal cortex and amygdala through fMRI-based neurofeedback to target adolescent socially-avoidant behaviour"],"prefix":"10.1016","volume":"135","author":[{"given":"Stephen","family":"Lisk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin Cohen","family":"Kadosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catharina","family":"Zich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone PW.","family":"Haller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer YF.","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.brat.2020.103760_bib1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1177\/1534582302001001003","article-title":"Recognizing emotion from facial expressions: Psychological and neurological mechanisms","volume":"1","author":"Adolphs","year":"2002","journal-title":"Behavioral and Cognitive Neuroscience Reviews"},{"key":"10.1016\/j.brat.2020.103760_bib2","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.dcn.2015.07.006","article-title":"Neurocognitive bases of emotion regulation development in adolescence","volume":"15","author":"Ahmed","year":"2015","journal-title":"Developmental Cognitive Neuroscience"},{"issue":"2","key":"10.1016\/j.brat.2020.103760_bib3","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.cpr.2009.11.004","article-title":"Emotion-regulation strategies across psychopathology: A meta-analytic review","volume":"30","author":"Aldao","year":"2010","journal-title":"Clinical Psychology Review"},{"issue":"3","key":"10.1016\/j.brat.2020.103760_bib4","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.psc.2009.06.002","article-title":"Anxiety and anxiety disorders in children and adolescents: Developmental issues and implications for DSM-V","volume":"32","author":"Beesdo","year":"2009","journal-title":"Psychiatric Clinics of North America"},{"issue":"7","key":"10.1016\/j.brat.2020.103760_bib5","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/jcpp.12383","article-title":"Practitioner review: Cognitive bias modification for mental health problems in children and adolescents: A meta-analysis","volume":"56","author":"Cristea","year":"2015","journal-title":"Journal of Child Psychology and Psychiatry"},{"issue":"4","key":"10.1016\/j.brat.2020.103760_bib6","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.yhbeh.2014.02.001","article-title":"Alleviating social avoidance: Effects of single dose testosterone administration on approach-avoidance action","volume":"65","author":"Enter","year":"2014","journal-title":"Hormones and Behavior"},{"issue":"6","key":"10.1016\/j.brat.2020.103760_bib7","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.paid.2006.04.010","article-title":"Cognitive emotion regulation questionnaire - development of a short 18-item version (CERQ-short)","volume":"41","author":"Garnefski","year":"2006","journal-title":"Personality and Individual Differences"},{"issue":"6","key":"10.1016\/j.brat.2020.103760_bib8","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1006\/jado.2002.0507","article-title":"Cognitive coping strategies and symptoms of depression and anxiety: A comparison between adolescents and adults","volume":"25","author":"Garnefski","year":"2002","journal-title":"Journal of Adolescence"},{"issue":"5","key":"10.1016\/j.brat.2020.103760_bib9","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/per.458","article-title":"The relationship between cognitive emotion regulation strategies and emotional problems: Comparison between a clinical and a non-clinical sample","volume":"16","author":"Garnefski","year":"2002","journal-title":"European Journal of Personality"},{"issue":"10","key":"10.1016\/j.brat.2020.103760_bib10","doi-asserted-by":"crossref","first-page":"4584","DOI":"10.1523\/JNEUROSCI.3446-12.2013","article-title":"A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry","volume":"33","author":"Gee","year":"2013","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.brat.2020.103760_bib11","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1001\/jamapsychiatry.2013.234","article-title":"Impact of cognitive behavioral therapy for social anxiety disorder on the neural dynamics of cognitive reappraisal of negative self-beliefs: Randomized clinical trial","volume":"70","author":"Goldin","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.brat.2020.103760_bib12","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.brat.2014.08.005","article-title":"Impact of cognitive-behavioral therapy for social anxiety disorder on the neural bases of emotional reactivity to and regulation of social evaluation","volume":"62","author":"Goldin","year":"2014","journal-title":"Behaviour Research and Therapy"},{"issue":"10","key":"10.1016\/j.brat.2020.103760_bib13","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1002\/da.22470","article-title":"Amygdala-cortical connectivity: Associations with anxiety, development, and threat","volume":"33","author":"Gold","year":"2016","journal-title":"Depression and Anxiety"},{"key":"10.1016\/j.brat.2020.103760_bib14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.dcn.2015.02.002","article-title":"Social anxiety disorder in adolescence: How developmental cognitive neuroscience findings may shape understanding and interventions for psychopathology","volume":"13","author":"Haller","year":"2015","journal-title":"Developmental Cognitive Neuroscience"},{"key":"10.1016\/j.brat.2020.103760_bib15","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.jbtep.2015.09.009","article-title":"Measuring online interpretations and attributions of social situations: Links with adolescent social anxiety","volume":"50","author":"Haller","year":"2016","journal-title":"Journal of Behavior Therapy and Experimental Psychiatry"},{"issue":"12","key":"10.1016\/j.brat.2020.103760_bib16","doi-asserted-by":"crossref","first-page":"2990","DOI":"10.1016\/j.brat.2007.08.010","article-title":"Avoidance of emotional facial expressions in social anxiety: The Approach-Avoidance Task","volume":"45","author":"Heuer","year":"2007","journal-title":"Behaviour Research and Therapy"},{"issue":"5","key":"10.1016\/j.brat.2020.103760_bib17","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.brat.2009.02.010","article-title":"How to handle anxiety: The effects of reappraisal, acceptance, and suppression strategies on anxious arousal","volume":"47","author":"Hofmann","year":"2009","journal-title":"Behaviour Research and Therapy"},{"issue":"1","key":"10.1016\/j.brat.2020.103760_bib18","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.neuroimage.2009.07.056","article-title":"Neurofeedback: A promising tool for the self-regulation of emotion networks","volume":"49","author":"Johnston","year":"2010","journal-title":"NeuroImage"},{"key":"10.1016\/j.brat.2020.103760_bib19","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.neuroimage.2015.09.070","article-title":"Using real-time fMRI to influence effective connectivity in the developing emotion regulation network","volume":"125","author":"Kadosh","year":"2016","journal-title":"NeuroImage"},{"issue":"2","key":"10.1016\/j.brat.2020.103760_bib20","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.bbr.2011.04.025","article-title":"The structural and functional connectivity of the amygdala: From normal emotion to pathological anxiety","volume":"223","author":"Kim","year":"2011","journal-title":"Behavioural Brain Research"},{"issue":"2","key":"10.1016\/j.brat.2020.103760_bib21","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/s10826-010-9402-7","article-title":"Approach and avoidance tendencies in spider fearful children: The approach-avoidance task","volume":"20","author":"Klein","year":"2011","journal-title":"Journal of Child and Family Studies"},{"issue":"2","key":"10.1016\/j.brat.2020.103760_bib22","first-page":"1193","article-title":"Learning control over emotion networks through connectivity-based neurofeedback","volume":"27","author":"Koush","year":"2017","journal-title":"Cerebral Cortex"},{"issue":"8","key":"10.1016\/j.brat.2020.103760_bib23","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1111\/jcpp.12809","article-title":"Research review: Cognitive bias modification of interpretations in youth and its effect on anxiety: A meta-analysis","volume":"59","author":"Krebs","year":"2018","journal-title":"Journal of Child Psychology and Psychiatry"},{"issue":"2","key":"10.1016\/j.brat.2020.103760_bib24","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1023\/A:1022684520514","article-title":"Social anxiety among adolescents: Linkages with peer relations and friendships","volume":"26","author":"La Greca","year":"1998","journal-title":"Journal of Abnormal Child Psychology"},{"issue":"3","key":"10.1016\/j.brat.2020.103760_bib48","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1002\/acp.1679","article-title":"Does modified interpretation bias influence automatic avoidance behaviour?","volume":"24","author":"Lange","year":"2010","journal-title":"Applied Cognitive Psychology"},{"issue":"5","key":"10.1016\/j.brat.2020.103760_bib25","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s10608-018-9912-y","article-title":"Multisession cognitive bias modification targeting multiple biases in adolescents with elevated social anxiety","volume":"42","author":"Lisk","year":"2018","journal-title":"Cognitive Therapy and Research"},{"issue":"6","key":"10.1016\/j.brat.2020.103760_bib26","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1080\/026999399379032","article-title":"Social anxiety and attention away from emotional faces","volume":"13","author":"Mansell","year":"1999","journal-title":"Cognition & Emotion"},{"issue":"3","key":"10.1016\/j.brat.2020.103760_bib27","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.pscychresns.2013.08.012","article-title":"Altered neural correlates of affective processing after internet-delivered cognitive behavior therapy for social anxiety disorder","volume":"214","author":"M\u00e5nsson","year":"2013","journal-title":"Psychiatry Research: Neuroimaging"},{"issue":"1","key":"10.1016\/j.brat.2020.103760_bib28","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1037\/1528-3542.5.1.119","article-title":"The effects of fear and anger facial expressions on approach- and avoidance-related behaviors","volume":"5","author":"Marsh","year":"2005","journal-title":"Emotion"},{"issue":"2","key":"10.1016\/j.brat.2020.103760_bib29","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jbtep.2006.12.002","article-title":"Why social anxiety persists: An experimental investigation of the role of safety behaviours as a maintaining factor","volume":"39","author":"Mcmanus","year":"2008","journal-title":"Journal of Behavior Therapy and Experimental Psychiatry"},{"issue":"8","key":"10.1016\/j.brat.2020.103760_bib30","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.janxdis.2014.09.008","article-title":"Developmental pathways of social avoidance across adolescence: The role of social anxiety and negative cognition","volume":"28","author":"Miers","year":"2014","journal-title":"Journal of Anxiety Disorders"},{"issue":"5","key":"10.1016\/j.brat.2020.103760_bib46","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1002\/jclp.22450","article-title":"Using Advances From Cognitive Behavioral Models of Anxiety to Guide Treatment for Social Anxiety Disorder","volume":"73","author":"Narr","year":"2017","journal-title":"J Clin Psychol"},{"issue":"8","key":"10.1016\/j.brat.2020.103760_bib31","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1162\/089892902760807212","article-title":"Rethinking feelings: An FMRI study of the cognitive regulation of emotion","volume":"14","author":"Ochsner","year":"2002","journal-title":"Journal of Cognitive Neuroscience"},{"issue":"5","key":"10.1016\/j.brat.2020.103760_bib32","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.tics.2005.03.010","article-title":"The cognitive control of emotion","volume":"9","author":"Ochsner","year":"2005","journal-title":"Trends in Cognitive Sciences"},{"issue":"2","key":"10.1016\/j.brat.2020.103760_bib33","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.tics.2004.12.008","article-title":"Mapping brain maturation and cognitive development during adolescence","volume":"9","author":"Paus","year":"2005","journal-title":"Trends in Cognitive Sciences"},{"key":"10.1016\/j.brat.2020.103760_bib34","doi-asserted-by":"crossref","first-page":"378","DOI":"10.3389\/fpsyg.2014.00378","article-title":"Approach, avoidance, and affect: A meta-analysis of approach-avoidance tendencies in manual reaction time tasks","volume":"5","author":"Phaf","year":"2014","journal-title":"Frontiers in Psychology"},{"issue":"3","key":"10.1016\/j.brat.2020.103760_bib35","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1002\/da.22014","article-title":"Aberrant amygdala-frontal cortex connectivity during perception of fearful faces and at rest in generalized social anxiety disorder","volume":"30","author":"Prater","year":"2013","journal-title":"Depression and Anxiety"},{"issue":"8","key":"10.1016\/j.brat.2020.103760_bib36","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1177\/0956797612472682","article-title":"Acting on anger: Social anxiety modulates approach-avoidance tendencies after oxytocin administration","volume":"24","author":"Radke","year":"2013","journal-title":"Psychological Science"},{"issue":"6","key":"10.1016\/j.brat.2020.103760_bib37","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.brat.2006.07.015","article-title":"Social anxiety disorder in childhood and adolescence: Descriptive psychopathology","volume":"45","author":"Rao","year":"2007","journal-title":"Behaviour Research and Therapy"},{"issue":"2","key":"10.1016\/j.brat.2020.103760_bib38","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jbtep.2006.10.001","article-title":"Approach and avoidance in fear of spiders","volume":"38","author":"Rinck","year":"2007","journal-title":"Journal of Behavior Therapy and Experimental Psychiatry"},{"issue":"4","key":"10.1016\/j.brat.2020.103760_bib39","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.brat.2009.11.008","article-title":"Gaze direction differentially affects avoidance tendencies to happy and angry faces in socially anxious individuals","volume":"48","author":"Roelofs","year":"2010","journal-title":"Behaviour Research and Therapy"},{"issue":"6","key":"10.1016\/j.brat.2020.103760_bib40","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1037\/0022-006X.67.6.995","article-title":"Treating anxiety disorders in children with group cognitive-behaviorial therapy: A randomized clinical trial'","volume":"67","author":"Silverman","year":"1999","journal-title":"Journal of Consulting and Clinical Psychology"},{"issue":"11","key":"10.1016\/j.brat.2020.103760_bib44","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1111\/jcpp.12822","article-title":"Research Review: Is anxiety associated with negative interpretations of ambiguity in children and adolescents? A systematic review and meta-analysis","volume":"59","author":"Stuijfzand","year":"2018","journal-title":"J Child Psychol Psychiatry"},{"issue":"7","key":"10.1016\/j.brat.2020.103760_bib41","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.janxdis.2009.05.004","article-title":"Social fears during adolescence: Is there an increase in distress and avoidance?'","volume":"23","author":"Sumter","year":"2009","journal-title":"Journal of Anxiety Disorders"},{"issue":"6","key":"10.1016\/j.brat.2020.103760_bib47","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1007\/s10608-011-9408-5","article-title":"Anticipation of Social Interaction Changes Implicit Approach-Avoidance Behavior of Socially Anxious Individuals","volume":"36","author":"Voncken","year":"2012","journal-title":"Cognit Ther Res"},{"key":"10.1016\/j.brat.2020.103760_bib42","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.pscychresns.2017.01.005","article-title":"Treatment for social anxiety disorder alters functional connectivity in emotion regulation neural circuitry","volume":"261","author":"Young","year":"2017","journal-title":"Psychiatry Research: Neuroimaging"},{"key":"10.1016\/j.brat.2020.103760_bib45","doi-asserted-by":"crossref","first-page":"117053","DOI":"10.1016\/j.neuroimage.2020.117053","article-title":"Modulatory effects of dynamic fMRI-based neurofeedback on emotion regulation networks in adolescent females","volume":"220","author":"Zich","year":"2020","journal-title":"Neuroimage"}],"container-title":["Behaviour Research and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000579672030214X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000579672030214X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T13:59:14Z","timestamp":1762091954000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000579672030214X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":47,"alternative-id":["S000579672030214X"],"URL":"https:\/\/doi.org\/10.1016\/j.brat.2020.103760","relation":{},"ISSN":["0005-7967"],"issn-type":[{"value":"0005-7967","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Training negative connectivity patterns between the dorsolateral prefrontal cortex and amygdala through fMRI-based neurofeedback to target adolescent socially-avoidant behaviour","name":"articletitle","label":"Article Title"},{"value":"Behaviour Research and Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brat.2020.103760","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"103760"}}