{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T00:22:53Z","timestamp":1760833373536,"version":"build-2065373602"},"reference-count":30,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,10,10]],"date-time":"2019-10-10T00:00:00Z","timestamp":1570665600000},"content-version":"vor","delay-in-days":2626,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thebreastonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Breast"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.breast.2012.03.008","type":"journal-article","created":{"date-parts":[[2012,4,17]],"date-time":"2012-04-17T23:01:47Z","timestamp":1334703707000},"page":"524-528","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Axillary and systemic treatment of patients with breast cancer and micrometastatic disease or isolated tumor cells in the sentinel lymph node"],"prefix":"10.1016","volume":"21","author":[{"given":"Adriana J.","family":"Maaskant-Braat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adri C.","family":"Voogd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lonneke V.","family":"van de Poll-Franse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Willem W.","family":"Coebergh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grard A.","family":"Nieuwenhuijzen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.breast.2012.03.008_bib1","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1093\/jnci\/90.21.1601","article-title":"Meeting highlights: international consensus panel on the treatment of primary breast cancer","volume":"90","author":"Glodhirsch","year":"1998","journal-title":"J\u00a0Natl Cancer Instit"},{"key":"10.1016\/j.breast.2012.03.008_bib2","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1056\/NEJM198503143121102","article-title":"Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation","volume":"312","author":"Fisher","year":"1985","journal-title":"N\u00a0Eng J Med"},{"key":"10.1016\/j.breast.2012.03.008_bib3","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s10434-999-0109-1","article-title":"The impact of prophylactic axillary node dissection on breast cancer survival \u2013 a Bayesian meta-analysis","volume":"6","author":"Orr","year":"1999","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2012.03.008_bib4","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1146\/annurev.med.51.1.525","article-title":"Lymphatic mapping and sentinel lymph node biopsy in patients with breast cancer","volume":"51","author":"Cox","year":"2000","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.breast.2012.03.008_bib5","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/S1470-2045(06)70947-0","article-title":"Sentinel-lymph-node biopsy as a staging procedure in breast cancer: update of a randomised controlled study","volume":"7","author":"Veronesi","year":"2006","journal-title":"Lancet Oncol"},{"issue":"4","key":"10.1016\/j.breast.2012.03.008_bib6","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1053\/ejso.2002.1385","article-title":"Comparison of morbidity between axillary lymph node dissection and sentinel node biopsy","volume":"29","author":"Schijven","year":"2003","journal-title":"Eur J Surg Oncol"},{"issue":"19","key":"10.1016\/j.breast.2012.03.008_bib7","doi-asserted-by":"crossref","first-page":"4312","DOI":"10.1200\/JCO.2005.03.228","article-title":"Morbidity after sentinel lymph node biopsy in primary breast cancer: results from a randomized controlled trial","volume":"23","author":"Purushotham","year":"2005","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.breast.2012.03.008_bib8","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1097\/00000658-199509000-00016","article-title":"Improved axillary staging of breast cancer with sentinel lymphadenectomy","volume":"222","author":"Giuliano","year":"1995","journal-title":"Ann Surg"},{"key":"10.1016\/j.breast.2012.03.008_bib9","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1023\/A:1012938825396","article-title":"Micro-metastases in axillary lymph nodes: an increasing classification and treatment dilemma in breast cancer due to the introduction of the sentinel lymph node procedure","volume":"70","author":"Tjan-Heijnen","year":"2001","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.breast.2012.03.008_bib10","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1200\/JCO.2007.12.6425","article-title":"Occult axillary node metastases in breast cancer are prognostically significant: results in 368 node-negative patients with 20-year follow-up","volume":"26","author":"Tan","year":"2008","journal-title":"J\u00a0Clin Onc"},{"key":"10.1016\/j.breast.2012.03.008_bib11","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.ejso.2006.04.001","article-title":"Introduction of sentinel node biopsy and stage migration of breast cancer","volume":"32","author":"van der Heiden-van der Loo","year":"2006","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.breast.2012.03.008_bib12","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/cncr.22069","article-title":"Additional axillary metastases and stage migration in breast cancer patients with micrometastases or submicrometastases in sentinel lymph nodes","volume":"107","author":"van Rijk","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.breast.2012.03.008_bib13","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s10549-008-9913-8","article-title":"Stage migration due to introduction of the sentinel node procedure: a population-based study","volume":"113","author":"Maaskant","year":"2009","journal-title":"Breast Cancer Res Treat"},{"issue":"12","key":"10.1016\/j.breast.2012.03.008_bib14","doi-asserted-by":"crossref","first-page":"3378","DOI":"10.1245\/s10434-007-9513-6","article-title":"The prognostic significance of micrometastases in breast cancer: a SEER population-based analysis","volume":"14","author":"Chen","year":"2007","journal-title":"Ann Surg Oncol"},{"issue":"7","key":"10.1016\/j.breast.2012.03.008_bib15","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1056\/NEJMoa0904832","article-title":"Micrometastases or isolated tumor cells and the outcome of breast cancer","volume":"361","author":"de Boer","year":"2009","journal-title":"N\u00a0Engl J Med"},{"issue":"1","key":"10.1016\/j.breast.2012.03.008_bib16","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/annonc\/mdn535","article-title":"Prognostic value of micrometastases in sentinel lymph nodes of patients with breast carcinoma: a cohort study","volume":"20","author":"Gobardhan","year":"2009","journal-title":"Ann Oncol"},{"key":"10.1016\/j.breast.2012.03.008_bib17","doi-asserted-by":"crossref","first-page":"4679","DOI":"10.1200\/JCO.2008.19.0686","article-title":"Impact of micrometastases in the sentinel node of patients with invasive breast cancer","volume":"27","author":"Hansen","year":"2009","journal-title":"J\u00a0Clin Oncol"},{"issue":"1","key":"10.1016\/j.breast.2012.03.008_bib18","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s10549-010-1086-6","article-title":"Sentinel node micrometastases in breast cancer do not affect prognosis: a population-based study","volume":"127","author":"Maaskant-Braat","year":"2011","journal-title":"Breast Cancer Res Treat"},{"year":"2005","author":"Nationaal Borstkanker Overleg Nederland (NABON)","series-title":"Richtlijn behandeling van het mammacarcinoom","key":"10.1016\/j.breast.2012.03.008_bib19"},{"key":"10.1016\/j.breast.2012.03.008_bib20","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/01.sla.0000150255.30665.52","article-title":"Predicting the risk for additional axillary metastases in patients with breast carcinoma and positive sentinel lymph node biopsy","volume":"241","author":"Viale","year":"2005","journal-title":"Ann Surg"},{"key":"10.1016\/j.breast.2012.03.008_bib21","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1002\/bjs.4725","article-title":"Meta-analysis of non-sentinel node metastases associated with micrometastatic sentinel nodes in breast cancer","volume":"91","author":"Cserni","year":"2004","journal-title":"Br J Surg"},{"year":"1987","first-page":"94","series-title":"UICC TNM classification of malignant tumors","key":"10.1016\/j.breast.2012.03.008_bib22"},{"key":"10.1016\/j.breast.2012.03.008_bib23","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1245\/ASO.2005.08.020","article-title":"The effect of sentinel node tumor burden on non-sentinel node status and recurrence rates in breast cancer","volume":"12","author":"Fan","year":"2005","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2012.03.008_bib24","doi-asserted-by":"crossref","first-page":"2946","DOI":"10.1200\/JCO.2008.19.5750","article-title":"Comparison of sentinel lymph node biopsy alone and completion axillary lymph node dissection for node-positive breast cancer","volume":"27","author":"Bilimoria","year":"2009","journal-title":"J\u00a0Clin Onc"},{"issue":"6","key":"10.1016\/j.breast.2012.03.008_bib25","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1001\/jama.2011.90","article-title":"Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial","volume":"305","author":"Giuliano","year":"2011","journal-title":"J\u00a0Am Med Assoc"},{"issue":"9503","key":"10.1016\/j.breast.2012.03.008_bib26","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1016\/S0140-6736(05)67887-7","article-title":"Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomized trials","volume":"366","author":"Clarke","year":"2005","journal-title":"Lancet"},{"issue":"9472","key":"10.1016\/j.breast.2012.03.008_bib27","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1016\/S0140-6736(05)66544-0","article-title":"Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomized trials","volume":"365","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.breast.2012.03.008_bib28","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1245\/ASO.2003.03.015","article-title":"A\u00a0nomogram for predicting the likelihood of additional nodal metastases in breast cancer patients with a positive sentinel node biopsy","volume":"10","author":"van Zee","year":"2003","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2012.03.008_bib29","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1002\/bjs.7186","article-title":"Value of Memorial Sloan-Kettering Cancer Center nomogram in clinical decision making for sentinel lymph node-positive breast cancer","volume":"97","author":"van den Hoven","year":"2010","journal-title":"Br J Surg"},{"key":"10.1016\/j.breast.2012.03.008_bib30","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.breast.2010.10.009","article-title":"Validating the MSKCC nomogram and a clinical decision rule in the prediction of non-sentinel node metastases in a Portuguese population of breast cancer patients","volume":"20","author":"Fougo","year":"2012","journal-title":"Breast"}],"container-title":["The Breast"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960977612000677?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960977612000677?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T08:30:10Z","timestamp":1760776210000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960977612000677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S0960977612000677"],"URL":"https:\/\/doi.org\/10.1016\/j.breast.2012.03.008","relation":{},"ISSN":["0960-9776"],"issn-type":[{"type":"print","value":"0960-9776"}],"subject":[],"published":{"date-parts":[[2012,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Axillary and systemic treatment of patients with breast cancer and micrometastatic disease or isolated tumor cells in the sentinel lymph node","name":"articletitle","label":"Article Title"},{"value":"The Breast","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.breast.2012.03.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}