{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:24:54Z","timestamp":1782210294687,"version":"3.54.5"},"reference-count":32,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thebreastonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Breast"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.breast.2015.08.001","type":"journal-article","created":{"date-parts":[[2015,9,3]],"date-time":"2015-09-03T22:25:08Z","timestamp":1441319108000},"page":"661-666","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":65,"title":["Neoadjuvant chemotherapy is not a contraindication for nipple sparing mastectomy"],"prefix":"10.1016","volume":"24","author":[{"given":"Stefano","family":"Santoro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Loreti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Cavaliere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leopoldo","family":"Costarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"La Pinta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Manna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Mauri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Scavina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Santini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugo","family":"De Paula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vito","family":"Toto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucio","family":"Fortunato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.breast.2015.08.001_bib1","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1053\/ejso.2001.1130","article-title":"Nipple-sparing mastectomy in breast cancer: a viable option?","volume":"27","author":"Cense","year":"2001","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib2","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1177\/1066896911399279","article-title":"Nipple involvement in breast cancer: retrospective analysis of 2323 consecutive mastectomy specimens","volume":"19","author":"Li","year":"2011","journal-title":"Int J Surg Pathol"},{"key":"10.1016\/j.breast.2015.08.001_bib3","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1245\/s10434-011-2107-3","article-title":"Predictors of nipple-areolar complex involvement by breast carcinoma: histopathologic analysis of 787 consecutive therapeutic mastectomy specimens","volume":"19","author":"Wang","year":"2012","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib4","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.jamcollsurg.2005.02.013","article-title":"Areola-sparing mastectomy: defining the risks","volume":"201","author":"Stolier","year":"2005","journal-title":"J\u00a0Am Coll Surg"},{"key":"10.1016\/j.breast.2015.08.001_bib5","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1001\/archsurg.143.11.1106","article-title":"Nipple-sparing mastectomy update: one hundred forty-nine procedures and clinical outcomes","volume":"143","author":"Crowe","year":"2008","journal-title":"Arch Surg"},{"key":"10.1016\/j.breast.2015.08.001_bib6","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/jso.23390","article-title":"When mastectomy is needed: is the nipple-sparing procedure a new standard with very few contraindications?","volume":"108","author":"Fortunato","year":"2013","journal-title":"J\u00a0Surg Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib7","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.amjsurg.2013.09.030","article-title":"Therapeutic nipple-sparing mastectomy: trends based on a national cancer database","volume":"208","author":"Agarwal","year":"2014","journal-title":"Am J Surg"},{"issue":"5","key":"10.1016\/j.breast.2015.08.001_bib8","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1097\/00006534-198711000-00007","article-title":"The psychological contribution of nipple addition in breast reconstruction","volume":"80","author":"Wellisch","year":"1987","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.breast.2015.08.001_bib9","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s10549-008-0238-4","article-title":"Does nipple preservation in mastectomy improve satisfaction with cosmetic results, psychological adjustment, body image and sexuality?","volume":"118","author":"Didier","year":"2009","journal-title":"Breast Cancer Res Treat"},{"issue":"6","key":"10.1016\/j.breast.2015.08.001_bib10","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1111\/j.1524-4741.2011.01220.x","article-title":"Defining a place for nipple sparing mastectomy in modern breast care: an evidence based review","volume":"19","author":"Murthy","year":"2013","journal-title":"Breast J"},{"issue":"5","key":"10.1016\/j.breast.2015.08.001_bib11","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1097\/PRS.0b013e3182865a3c","article-title":"The role of nipple-sparing mastectomy in breast cancer: a comprehensive review of the literature","volume":"131","author":"Mallon","year":"2013","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.breast.2015.08.001_bib12","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ejso.2011.09.005","article-title":"Surgical complications of skin sparing mastectomy and immediate prosthetic reconstruction after neoadjuvant chemotherapy for invasive breast cancer","volume":"38","author":"Donker","year":"2012","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib13","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.1002\/cncr.25872","article-title":"Impact of neoadjuvant chemotherapy on breast reconstruction","volume":"117","author":"Hu","year":"2011","journal-title":"Cancer"},{"key":"10.1016\/j.breast.2015.08.001_bib14","doi-asserted-by":"crossref","first-page":"3218","DOI":"10.1245\/s10434-013-3152-x","article-title":"Increasing eligibility for nipple-sparing mastectomy","volume":"20","author":"Coopey","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib15","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.amjsurg.2014.04.001","article-title":"Breast cancer recurrence after nipple-sparing mastectomy: one institution's experience","volume":"209","author":"Poruk","year":"2015","journal-title":"Am J Surg"},{"issue":"24","key":"10.1016\/j.breast.2015.08.001_bib16","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1093\/annonc\/mdt303","article-title":"Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer","volume":"2013","author":"Goldhirsch","year":"2013","journal-title":"Ann Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib17","doi-asserted-by":"crossref","first-page":"3294","DOI":"10.1245\/s10434-013-3174-4","article-title":"Nipple skin-sparing mastectomy is feasible for advanced disease","volume":"20","author":"Burdge","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib18","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1177\/145749691009900302","article-title":"Early complications after nipple-sparing mastectomy and immediate breast reconstruction with silicone prosthesis: results of 214 procedures","volume":"99","author":"Radovanovic","year":"2010","journal-title":"Scand J Surg"},{"key":"10.1016\/j.breast.2015.08.001_bib19","first-page":"75","article-title":"Nipple sparing mastectomy: from prophylactic to therapeutic standard","volume":"1","author":"Lohsiriwat","year":"2012","journal-title":"Gland Surg"},{"key":"10.1016\/j.breast.2015.08.001_bib20","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.bjps.2012.12.014","article-title":"Nipple-sparing mastectomy: what is the frontier between oncologic safety and cosmetic outcome?","volume":"66","author":"Conde","year":"2013","journal-title":"J\u00a0Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.breast.2015.08.001_bib21","doi-asserted-by":"crossref","first-page":"3123","DOI":"10.1245\/s10434-011-2008-5","article-title":"Preoperative predictors of nipple-areola complex involvement for patients undergoing mastectomy for breast cancer","volume":"18","author":"Billar","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib22","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1016\/j.ejca.2012.04.017","article-title":"Clinical and radiological predictors of nipple-areola complex involvement in breast cancer patients","volume":"48","author":"D'Alonzo","year":"2012","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.breast.2015.08.001_bib23","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1245\/s10434-012-2641-7","article-title":"Predicting nipple-areolar involvement using preoperative breast MRI and primary tumor characteristics","volume":"20","author":"Steen","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib24","doi-asserted-by":"crossref","first-page":"4948","DOI":"10.1200\/JCO.2008.20.8785","article-title":"Occult nipple involvement in breast cancer: clinicopathologic findings in 316 consecutive mastectomy specimens","volume":"27","author":"Brachtel","year":"2009","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib25","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/tbj.12199","article-title":"Pathological evaluation of nipple-sparing mastectomies with emphasis on occult nipple involvement: the Weill-Cornell experience with 325 cases","volume":"20","author":"Eisenberg","year":"2014","journal-title":"Breast J"},{"key":"10.1016\/j.breast.2015.08.001_bib26","doi-asserted-by":"crossref","first-page":"4117","DOI":"10.1245\/s10434-012-2514-0","article-title":"Risk of locoregional recurrence in patients with false-negative frozen section or close margins of retroareolar specimen in nipple-sparing mastectomy","volume":"19","author":"Kneubil","year":"2012","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib27","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.breast.2011.09.010","article-title":"Improved sub-areola breast tissue removal in nipple-sparing mastectomy using hydrodissection","volume":"21","author":"Folli","year":"2012","journal-title":"Breast"},{"key":"10.1016\/j.breast.2015.08.001_bib28","doi-asserted-by":"crossref","first-page":"3402","DOI":"10.1245\/s10434-012-2362-y","article-title":"Outcomes after total skin-sparing mastectomy and immediate reconstruction in 657 breasts","volume":"19","author":"Warren Peled","year":"2012","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2015.08.001_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/PRS.0b013e3181da8699","article-title":"Influence of neoadjuvant chemotherapy on outcomes of immediate breast reconstruction","volume":"126","author":"Azzawi","year":"2010","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.breast.2015.08.001_bib30","first-page":"55","article-title":"Does neoadjuvant chemotherapy for breast cancer increase complications during immediate breast reconstruction?","volume":"56","author":"Liu","year":"2009","journal-title":"J\u00a0Med Dent Sci"},{"key":"10.1016\/j.breast.2015.08.001_bib31","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/PRS.0b013e3181aee807","article-title":"Development of a new patient-reported outcome measure for breast surgery: the BREAST-Q","volume":"124","author":"Pusic","year":"2009","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.breast.2015.08.001_bib32","article-title":"Nipple-sparing mastectomy: are we compromising oncologic safety for cosmesis?","volume":"23","author":"Oppong","year":"2012","journal-title":"Breast Dis"}],"container-title":["The Breast"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960977615001782?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960977615001782?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T08:33:52Z","timestamp":1760776432000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960977615001782"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S0960977615001782"],"URL":"https:\/\/doi.org\/10.1016\/j.breast.2015.08.001","relation":{},"ISSN":["0960-9776"],"issn-type":[{"value":"0960-9776","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neoadjuvant chemotherapy is not a contraindication for nipple sparing mastectomy","name":"articletitle","label":"Article Title"},{"value":"The Breast","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.breast.2015.08.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}