{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T18:42:55Z","timestamp":1787596975330,"version":"build-2736575974"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,10,29]],"date-time":"2019-10-29T00:00:00Z","timestamp":1572307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thebreastonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Breast"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.breast.2019.10.017","type":"journal-article","created":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T15:09:09Z","timestamp":1573052949000},"page":"63-69","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Outcome of breast-conserving treatment for axillary lymph node metastasis from occult breast cancer with negative breast MRI"],"prefix":"10.1016","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1808-7573","authenticated-orcid":false,"given":"Haeyoung","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su Ssan","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Ja","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Bae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Hee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Hwa","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hae Jin","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7685-3382","authenticated-orcid":false,"given":"Jee Suk","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doo Ho","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.breast.2019.10.017_bib1","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0959-8049(01)00378-1","article-title":"Epidemiology of unknown primary tumours; incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984-1992","volume":"38","author":"van de Wouw","year":"2002","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.breast.2019.10.017_bib2","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1080\/02841860902862503","article-title":"Cancer patients without a known primary: incidence and survival trends in Sweden 1960-2007","volume":"48","author":"Randen","year":"2009","journal-title":"Acta Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib3","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1093\/annonc\/mdr536","article-title":"Survival in cancer of unknown primary site: population-based analysis by site and histology","volume":"23","author":"Hemminki","year":"2012","journal-title":"Ann Oncol : Off J Eur Soc Med Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10549-009-0554-3","article-title":"Axillary nodal metastases from carcinoma of unknown primary (CUPAx): a systematic review of published evidence","volume":"119","author":"Pentheroudakis","year":"2010","journal-title":"Breast Canc Res Treat"},{"key":"10.1016\/j.breast.2019.10.017_bib5","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/00000658-197604000-00015","article-title":"Breast cancer presenting as an axillary mass","volume":"183","author":"Ashikari","year":"1976","journal-title":"Ann Surg"},{"key":"10.1016\/j.breast.2019.10.017_bib6","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/jso.23644","article-title":"Treatment and survival of patients with occult breast cancer with axillary lymph node metastasis: a nationwide retrospective study","volume":"110","author":"Sohn","year":"2014","journal-title":"J\u00a0Surg Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib7","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1038\/bjc.2013.386","article-title":"Cancer of unknown primary: a population-based analysis of temporal change and socioeconomic disparities","volume":"109","author":"Urban","year":"2013","journal-title":"Br J Canc"},{"key":"10.1016\/j.breast.2019.10.017_bib8","unstructured":"Occult primary (cancer of unknown primary, CUP) (Version 1. 2019) [https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/occult.pdf]."},{"key":"10.1016\/j.breast.2019.10.017_bib9","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1245\/s10434-016-5104-8","article-title":"Optimal surgical management for occult breast carcinoma: a meta-analysis","volume":"23","author":"Macedo","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib10","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1245\/s10434-017-5928-x","article-title":"Factors influencing management and outcome in patients with occult breast cancer with axillary lymph node involvement: analysis of the national cancer database","volume":"24","author":"Hessler","year":"2017","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib11","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s10434-000-0411-4","article-title":"Magnetic resonance imaging facilitates breast conservation for occult breast cancer","volume":"7","author":"Olson","year":"2000","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib12","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1245\/ASO.2005.03.520","article-title":"Utility of breast magnetic resonance imaging in patients with occult primary breast cancer","volume":"12","author":"Buchanan","year":"2005","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib13","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1245\/s10434-014-3991-0","article-title":"Breast conservation in the setting of contemporary multimodality treatment provides excellent outcomes for patients with occult primary breast cancer","volume":"22","author":"Rueth","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib14","doi-asserted-by":"crossref","first-page":"3141","DOI":"10.1245\/s10434-017-5965-5","article-title":"Oncologic outcomes after treatment for MRI occult breast cancer (pT0N+)","volume":"24","author":"McCartan","year":"2017","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib15","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.clon.2010.10.001","article-title":"Breast radiotherapy for occult breast cancer with axillary nodal metastases--does it reduce the local recurrence rate and increase overall survival?","volume":"23","author":"Masinghe","year":"2011","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"10.1016\/j.breast.2019.10.017_bib16","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1016\/j.ejca.2011.05.010","article-title":"The role of ipsilateral breast radiotherapy in management of occult primary breast cancer presenting as axillary lymphadenopathy","volume":"47","author":"Barton","year":"2011","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.breast.2019.10.017_bib17","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1148\/radiol.2251011667","article-title":"Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: an analysis of 27,825 patient evaluations","volume":"225","author":"Kolb","year":"2002","journal-title":"Radiology"},{"key":"10.1016\/j.breast.2019.10.017_bib18","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.ejso.2012.08.022","article-title":"Treatment outcomes and unfavorable prognostic factors in patients with occult breast cancer","volume":"38","author":"He","year":"2012","journal-title":"Eur J Surg Oncol : J Eur Soc Surg Oncol Br Assoc Surg Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib19","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1001\/archsurg.1990.01410140088014","article-title":"Occult breast cancer presenting with axillary metastases. Updated management","volume":"125","author":"Baron","year":"1990","journal-title":"Arch Surg"},{"key":"10.1016\/j.breast.2019.10.017_bib20","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1002\/1097-0142(19920715)70:2<504::AID-CNCR2820700221>3.0.CO;2-T","article-title":"Breast carcinoma presenting as axillary metastases without evidence of a primary tumor","volume":"70","author":"Merson","year":"1992","journal-title":"Cancer"},{"key":"10.1016\/j.breast.2019.10.017_bib21","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1001\/jama.2012.388","article-title":"Detection of breast cancer with addition of annual screening ultrasound or a single screening MRI to mammography in women with elevated breast cancer risk","volume":"307","author":"Berg","year":"2012","journal-title":"J\u00a0Am Med Assoc"},{"key":"10.1016\/j.breast.2019.10.017_bib22","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1001\/jamaoncol.2017.1256","article-title":"Breast cancer screening with mammography plus ultrasonography or magnetic resonance imaging in women 50 Years or younger at diagnosis and treated with breast conservation therapy","volume":"3","author":"Cho","year":"2017","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib23","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.ejso.2009.09.007","article-title":"Breast MRI in clinically and mammographically occult breast cancer presenting with an axillary metastasis: a systematic review","volume":"36","author":"de Bresser","year":"2010","journal-title":"Eur J Surg Oncol : J Eur Soc Surg Oncol Br Assoc Surg Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib24","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.amjsurg.2005.06.026","article-title":"Therapeutic options for occult breast cancer: a survey of the American Society of Breast Surgeons and review of the literature","volume":"190","author":"Khandelwal","year":"2005","journal-title":"Am J Surg"},{"key":"10.1016\/j.breast.2019.10.017_bib25","doi-asserted-by":"crossref","first-page":"551","DOI":"10.4143\/crt.2017.189","article-title":"Evaluation of the benefit of radiotherapy in patients with occult breast cancer: a population-based analysis of the SEER database","volume":"50","author":"Kim","year":"2018","journal-title":"Cancer Res Treat"},{"issue":"1","key":"10.1016\/j.breast.2019.10.017_bib26","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s10549-019-05285-x","article-title":"The effect of local therapy on breast cancer-specific mortality of women with occult breast cancer and advanced nodal disease (N2\/N3): a population analysis","volume":"177","author":"Johnson","year":"2019","journal-title":"Breast Canc Res Treat"},{"key":"10.1016\/j.breast.2019.10.017_bib27","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.1245\/s10434-013-3157-5","article-title":"Geographic and temporal trends in the management of occult primary breast cancer: a systematic review and meta-analysis","volume":"20","author":"Fayanju","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib28","first-page":"410","article-title":"Survival outcomes of different treatment methods for the ipsilateral breast of occult breast cancer patients with axillary lymph node metastasis: a single center experience","volume":"16","author":"Woo","year":"2013","journal-title":"J\u00a0Breast Canc"},{"issue":"Suppl 2","key":"10.1016\/j.breast.2019.10.017_bib29","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1016\/j.breast.2015.07.008","article-title":"Clinical implications of the intrinsic molecular subtypes of breast cancer","volume":"24","author":"Prat","year":"2015","journal-title":"Breast"},{"key":"10.1016\/j.breast.2019.10.017_bib30","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.soc.2017.08.005","article-title":"Molecular subtypes and local-regional control of breast cancer","volume":"27","author":"Fragomeni","year":"2018","journal-title":"Surg Oncol Clin N Am"},{"key":"10.1016\/j.breast.2019.10.017_bib31","first-page":"70","article-title":"Chronological improvement in survival of patients with breast cancer: a large-scale, single-center study","volume":"21","author":"Lee","year":"2018","journal-title":"J\u00a0Breast Canc"},{"key":"10.1016\/j.breast.2019.10.017_bib32","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1200\/JCO.2015.62.1797","article-title":"Adjuvant lapatinib and trastuzumab for early human epidermal growth factor receptor 2-positive breast cancer: results from the randomized phase III adjuvant lapatinib and\/or trastuzumab treatment optimization trial","volume":"34","author":"Piccart-Gebhart","year":"2016","journal-title":"J\u00a0Clin Oncol : Off J Am Soc Clin Oncol"},{"key":"10.1016\/j.breast.2019.10.017_bib33","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.clon.2017.06.003","article-title":"Neoadjuvant therapy in early breast cancer: treatment considerations and common debates in practice","volume":"29","author":"Cain","year":"2017","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"10.1016\/j.breast.2019.10.017_bib34","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1056\/NEJMra1303917","article-title":"Cancer of unknown primary site","volume":"371","author":"Varadhachary","year":"2014","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.breast.2019.10.017_bib35","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1053\/j.sult.2017.10.001","article-title":"Molecular breast imaging: a comprehensive review","volume":"39","author":"Huppe","year":"2018","journal-title":"Semin Ultrasound CT MR"}],"container-title":["The Breast"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960977619305910?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960977619305910?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T08:41:41Z","timestamp":1760776901000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960977619305910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":35,"alternative-id":["S0960977619305910"],"URL":"https:\/\/doi.org\/10.1016\/j.breast.2019.10.017","relation":{},"ISSN":["0960-9776"],"issn-type":[{"value":"0960-9776","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcome of breast-conserving treatment for axillary lymph node metastasis from occult breast cancer with negative breast MRI","name":"articletitle","label":"Article Title"},{"value":"The Breast","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.breast.2019.10.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}