{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:31:31Z","timestamp":1783776691372,"version":"3.55.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["brainstimjrnl.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Stimulation"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.brs.2012.04.012","type":"journal-article","created":{"date-parts":[[2012,5,23]],"date-time":"2012-05-23T17:17:34Z","timestamp":1337793454000},"page":"286-291","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Functional Plasticity of the Motor Cortical Structures Demonstrated by Navigated TMS in Two Patients with Epilepsy"],"prefix":"10.1016","volume":"6","author":[{"given":"Jyrki P.","family":"M\u00e4kel\u00e4","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Mari","family":"Vitikainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pantelis","family":"Lioumis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritva","family":"Paetau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eero","family":"Ahtola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Kuusela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leena","family":"Valanne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6ran","family":"Blomstedt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eija","family":"Gaily","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brs.2012.04.012_bib1","unstructured":"Meyer BU. Introduction to diagnostic strategies of magnetic stimulation. In: Pascual-Leone A, Davey NJ, Rothwell JC, Wassermann EM, Puri BK, eds. Handbook of transcranial magnetic stimulation London: Arnold Publishers. pp 177\u2013184."},{"key":"10.1016\/j.brs.2012.04.012_bib2","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1227\/NEU.0b013e31820b528c","article-title":"Navigated transcranial magnetic stimulation and functional magnetic resonance imaging \u2013 advanced adjuncts in preoperative planning for central region tumors","volume":"68","author":"Forster","year":"2011","journal-title":"Neurosurgery"},{"key":"10.1016\/j.brs.2012.04.012_bib3","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1227\/NEU.0b013e3182181b89","article-title":"Preoperative functional mapping for Rolandic brain tumor surgery: comparison of navigated transcranial magnetic stimulation to direct cortical stimulation","volume":"69","author":"Picht","year":"2011","journal-title":"Neurosurgery"},{"key":"10.1016\/j.brs.2012.04.012_bib4","article-title":"Utility of presurgical navigatred transcranial braiun stimulation for the resection of tumors in eloquent motor areas","author":"Krieg","year":"2012","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.brs.2012.04.012_bib5","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.eplepsyres.2010.08.013","article-title":"Non-invasive preoperative localization of primary motor cortex in epilepsy surgery by navigated transcranial magnetic stimulation","volume":"92","author":"S\u00e4is\u00e4nen","year":"2010","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.brs.2012.04.012_bib6","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.neuroimage.2008.12.026","article-title":"Combined use of non-invasive techniques for improved functional localization for a selected group of epilepsy surgery candidates","volume":"45","author":"Vitikainen","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.brs.2012.04.012_bib7","doi-asserted-by":"crossref","unstructured":"Pouratian N, Bookheimer SY. The reliability of neuroanatomy as a predictor of eloquence: a review. Neurosurg Focus 28: E3.","DOI":"10.3171\/2009.11.FOCUS09239"},{"issue":"Pt 1","key":"10.1016\/j.brs.2012.04.012_bib8","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/brain\/120.1.141","article-title":"Localization of the motor hand area to a knob on the precentral gyrus. A new landmark","volume":"120","author":"Yousry","year":"1997","journal-title":"Brain"},{"key":"10.1016\/j.brs.2012.04.012_bib9","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.seizure.2003.11.003","article-title":"Motor cortical thresholds and cortical silent periods in epilepsy","volume":"13","author":"Tataroglu","year":"2004","journal-title":"Seizure"},{"key":"10.1016\/j.brs.2012.04.012_bib10","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/1097-0193(200103)12:3<180::AID-HBM1014>3.0.CO;2-N","article-title":"Three-dimensional imaging of functional brain anatomy to facilitate intraoperative navigation around the somatomotor strip","volume":"12","author":"M\u00e4kel\u00e4","year":"2001","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.brs.2012.04.012_bib11","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1111\/j.1469-8749.2000.tb00698.x","article-title":"Reorganization of the primary somatosensory area in epilepsy associated with focal cortical dysplasia","volume":"42","author":"Gondo","year":"2000","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.brs.2012.04.012_bib12","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.neuroimage.2006.09.005","article-title":"Fibers from the dorsal premotor cortex elicit motor-evoked potential in a cortical dysplasia","volume":"34","author":"Mikuni","year":"2007","journal-title":"Neuroimage"},{"key":"10.1016\/j.brs.2012.04.012_bib13","first-page":"113","article-title":"Function and organization in dysgenic cortex. Case report","volume":"87","author":"Preul","year":"1997","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.brs.2012.04.012_bib14","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.eplepsyres.2007.06.004","article-title":"Motor representation areas in epileptic patients with focal motor seizures: a TMS study","volume":"75","author":"Labyt","year":"2007","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.brs.2012.04.012_bib15","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/00004691-200302000-00002","article-title":"Functional variability of the human cortical motor map: electrical stimulation findings in perirolandic epilepsy surgery","volume":"20","author":"Branco","year":"2003","journal-title":"J\u00a0Clin Neurophysiol"},{"key":"10.1016\/j.brs.2012.04.012_bib16","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.eplepsyres.2007.07.007","article-title":"Young patients with focal seizures may have the primary motor area for the hand in the postcentral sulcus","volume":"76","author":"Haseeb","year":"2007","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.brs.2012.04.012_bib17","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1212\/WNL.46.2.360","article-title":"Does central sulcus divide motor and sensory functions?","volume":"46","author":"Nii","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.brs.2012.04.012_bib18","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1111\/j.1528-1167.2005.00284.x","article-title":"In\u00a0vivo epileptogenicity of focal cortical dysplasia: a direct cortical paired stimulation study","volume":"46","author":"Matsumoto","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.brs.2012.04.012_bib19","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.eplepsyres.2009.03.016","article-title":"Unaffected motor cortex remodeling after hemispherectomy in an epileptic cerebral palsy patient. A TMS and fMRI study","volume":"85","author":"Pilato","year":"2009","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.brs.2012.04.012_bib20","series-title":"Epilepsy and the functional anatomy of the human brain","first-page":"692","article-title":"Electrocorticography","author":"Penfield","year":"1954"},{"key":"10.1016\/j.brs.2012.04.012_bib21","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0006-8993(90)91553-S","article-title":"Gating of somatosensory input by human prefrontal cortex","volume":"521","author":"Yamaguchi","year":"1990","journal-title":"Brain Res"},{"key":"10.1016\/j.brs.2012.04.012_bib22","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.neuroimage.2007.12.065","article-title":"Non-primary motor areas in the human frontal lobe are connected directly to hand muscles","volume":"40","author":"Teitti","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.brs.2012.04.012_bib23","doi-asserted-by":"crossref","unstructured":"Kombos T, S\u00fcss O. Neurophysiological basis of direct cortical stimulation and applied\u00a0neuroanatomy of the motor cortex: a review. Neurosurg Focus. 2009;27: E3.","DOI":"10.3171\/2009.8.FOCUS09141"},{"key":"10.1016\/j.brs.2012.04.012_bib24","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1177\/088307380201700411","article-title":"Interhemispheric reorganization of motor hand function to the primary motor cortex predicted with functional magnetic resonance imaging and transcranial magnetic stimulation","volume":"17","author":"Rutten","year":"2002","journal-title":"J\u00a0Child Neurol"},{"key":"10.1016\/j.brs.2012.04.012_bib25","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3171\/ped.2004.101.2.0069","article-title":"Searching for\u00a0motor functions in dysgenic cortex: a clinical transcranial magnetic stimulation and functional magnetic resonance imaging study","volume":"101","author":"Staudt","year":"2004","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.brs.2012.04.012_bib26","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.pediatrneurol.2010.08.017","article-title":"Transfer of cortical motor representation after a perinatal cerebral insult","volume":"44","author":"Thordstein","year":"2011","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.brs.2012.04.012_bib27","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1148\/radiol.2411050796","article-title":"Sensorimotor cortex localization: comparison of magnetoencephalography, functional MR imaging, and intraoperative cortical mapping","volume":"241","author":"Korvenoja","year":"2006","journal-title":"Radiology"},{"key":"10.1016\/j.brs.2012.04.012_bib28","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1097\/01.wco.0000170242.63948.17","article-title":"Alternatives to the Wada test: a critical view of functional magnetic resonance imaging in preoperative use","volume":"18","author":"Kl\u00f6ppel","year":"2005","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.brs.2012.04.012_bib29","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/nrn1119","article-title":"Looking into the functional architecture of the brain with diffusion MRI","volume":"4","author":"Le Bihan","year":"2003","journal-title":"Nat Rev Neurosci"}],"container-title":["Brain Stimulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X12000800?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X12000800?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T14:06:07Z","timestamp":1761833167000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1935861X12000800"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S1935861X12000800"],"URL":"https:\/\/doi.org\/10.1016\/j.brs.2012.04.012","relation":{},"ISSN":["1935-861X"],"issn-type":[{"value":"1935-861X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Functional Plasticity of the Motor Cortical Structures Demonstrated by Navigated TMS in Two Patients with Epilepsy","name":"articletitle","label":"Article Title"},{"value":"Brain Stimulation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brs.2012.04.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}