{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:45:32Z","timestamp":1791261932747,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["brainstimjrnl.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Stimulation"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.brs.2016.06.051","type":"journal-article","created":{"date-parts":[[2016,6,23]],"date-time":"2016-06-23T05:12:33Z","timestamp":1466658753000},"page":"892-896","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":121,"title":["Closed-Loop Deep Brain Stimulation Effects on Parkinsonian Motor Symptoms in a Non-Human Primate \u2013 Is Beta Enough?"],"prefix":"10.1016","volume":"9","author":[{"given":"Luke A.","family":"Johnson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6120-5999","authenticated-orcid":false,"given":"Shane D.","family":"Nebeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abirami","family":"Muralidharan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew D.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth B.","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerrold L.","family":"Vitek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.brs.2016.06.051_bib0010","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.conb.2003.11.001","article-title":"Deep brain stimulation for Parkinson's disease","volume":"13","author":"Benabid","year":"2003","journal-title":"Curr Opin Neurobiol"},{"issue":"1","key":"10.1016\/j.brs.2016.06.051_bib0015","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1749-6632.2012.06650.x","article-title":"What brain signals are suitable for feedback control of deep brain stimulation in Parkinson's disease?","volume":"1265","author":"Little","year":"2012","journal-title":"Ann N Y Acad Sci"},{"issue":"22","key":"10.1016\/j.brs.2016.06.051_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.cub.2006.10.013","article-title":"Deep brain stimulation of the subthalamic nucleus: a two-edged sword","volume":"16","author":"Chen","year":"2006","journal-title":"Curr Biol"},{"issue":"4","key":"10.1016\/j.brs.2016.06.051_bib0025","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/mds.10358","article-title":"Oscillatory nature of human basal ganglia activity: relationship to the pathophysiology of Parkinson's disease","volume":"18","author":"Brown","year":"2003","journal-title":"Mov Disord"},{"issue":"2","key":"10.1016\/j.brs.2016.06.051_bib0030","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.expneurol.2004.06.001","article-title":"Rhythm-specific pharmacological modulation of subthalamic activity in Parkinson's disease","volume":"189","author":"Priori","year":"2004","journal-title":"Exp Neurol"},{"issue":"2","key":"10.1016\/j.brs.2016.06.051_bib0035","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.expneurol.2008.11.008","article-title":"Pathological synchronisation in the subthalamic nucleus of patients with Parkinson's disease relates to both bradykinesia and rigidity","volume":"215","author":"Kuhn","year":"2009","journal-title":"Exp Neurol"},{"issue":"52","key":"10.1016\/j.brs.2016.06.051_bib0040","doi-asserted-by":"crossref","first-page":"14245","DOI":"10.1523\/JNEUROSCI.4199-08.2008","article-title":"Parkinsonian beta oscillations in the external globus pallidus and their relationship with subthalamic nucleus activity","volume":"28","author":"Mallet","year":"2008","journal-title":"J Neurosci"},{"issue":"5","key":"10.1016\/j.brs.2016.06.051_bib0045","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1111\/j.1460-9568.2005.03973.x","article-title":"Dopamine depletion increases the power and coherence of \u03b2-oscillations in the cerebral cortex and subthalamic nucleus of the awake rat","volume":"21","author":"Sharott","year":"2005","journal-title":"Eur J Neurosci"},{"issue":"Pt 2","key":"10.1016\/j.brs.2016.06.051_bib0050","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1093\/brain\/124.2.378","article-title":"Subthalamic nucleus, sensorimotor cortex and muscle interrelationships in Parkinson's disease","volume":"124","author":"Marsden","year":"2001","journal-title":"Brain"},{"issue":"3","key":"10.1016\/j.brs.2016.06.051_bib0055","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1523\/JNEUROSCI.21-03-01033.2001","article-title":"Dopamine dependency of oscillations between subthalamic nucleus and pallidum in Parkinson's disease","volume":"21","author":"Brown","year":"2001","journal-title":"J Neurosci"},{"issue":"Pt 6","key":"10.1016\/j.brs.2016.06.051_bib0060","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1093\/brain\/awf128","article-title":"Dependence of subthalamic nucleus oscillations on movement and dopamine in Parkinson's disease","volume":"125","author":"Levy","year":"2002","journal-title":"Brain"},{"issue":"1","key":"10.1016\/j.brs.2016.06.051_bib0065","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.expneurol.2010.08.011","article-title":"The effects of levodopa and ongoing deep brain stimulation on subthalamic beta oscillations in Parkinson's disease","volume":"226","author":"Giannicola","year":"2010","journal-title":"Exp Neurol"},{"issue":"5","key":"10.1016\/j.brs.2016.06.051_bib0070","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1136\/jnnp.2010.217489","article-title":"Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients","volume":"82","author":"Eusebio","year":"2011","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.brs.2016.06.051_bib0075","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3389\/fnhum.2012.00155","article-title":"High frequency deep brain stimulation attenuates subthalamic and cortical rhythms in Parkinson's disease","volume":"6","author":"Whitmer","year":"2012","journal-title":"Front Hum Neurosci"},{"issue":"3","key":"10.1016\/j.brs.2016.06.051_bib0080","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1002\/ana.23951","article-title":"Adaptive deep brain stimulation in advanced Parkinson disease","volume":"74","author":"Little","year":"2013","journal-title":"Ann Neurol"},{"issue":"7","key":"10.1016\/j.brs.2016.06.051_bib0085","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1002\/mds.26241","article-title":"Adaptive deep brain stimulation in a freely moving Parkinsonian patient","volume":"30","author":"Rosa","year":"2015","journal-title":"Mov Disord"},{"key":"10.1016\/j.brs.2016.06.051_bib0090","article-title":"Bilateral adaptive deep brain stimulation is effective in Parkinson's disease","author":"Little","year":"2015","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.brs.2016.06.051_bib0095","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.expneurol.2012.09.013","article-title":"Adaptive deep brain stimulation (aDBS) controlled by local field potential oscillations","volume":"245","author":"Priori","year":"2013","journal-title":"Exp Neurol"},{"issue":"5","key":"10.1016\/j.brs.2016.06.051_bib0100","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1523\/JNEUROSCI.23-05-01916.2003","article-title":"Stimulation of the subthalamic nucleus changes the firing pattern of pallidal neurons","volume":"23","author":"Hashimoto","year":"2003","journal-title":"J Neurosci"},{"issue":"Pt 4","key":"10.1016\/j.brs.2016.06.051_bib0105","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1093\/brain\/awh106","article-title":"Event-related beta desynchronization in human subthalamic nucleus correlates with motor performance","volume":"127","author":"Kuhn","year":"2004","journal-title":"Brain"},{"issue":"6","key":"10.1016\/j.brs.2016.06.051_bib0110","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1093\/brain\/awf135","article-title":"Movement-related changes in synchronization in the human basal ganglia","volume":"125","author":"Cassidy","year":"2002","journal-title":"Brain"},{"issue":"Pt 4","key":"10.1016\/j.brs.2016.06.051_bib0115","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/brain\/121.4.755","article-title":"The reaching movements of patients with Parkinson's disease under self-determined maximal speed and visually cued conditions","volume":"121","author":"Majsak","year":"1998","journal-title":"Brain"},{"issue":"11","key":"10.1016\/j.brs.2016.06.051_bib0120","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/0166-2236(91)90055-Y","article-title":"Paradoxical movement in Parkinson's disease","volume":"14","author":"Glickstein","year":"1991","journal-title":"Trends Neurosci"},{"issue":"7","key":"10.1016\/j.brs.2016.06.051_bib0125","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/S0028-3932(02)00286-5","article-title":"Effects of deep brain stimulation on prehensile movements in PD patients are less pronounced when external timing cues are provided","volume":"41","author":"Schenk","year":"2003","journal-title":"Neuropsychologia"},{"issue":"9","key":"10.1016\/j.brs.2016.06.051_bib0130","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1002\/mds.10493","article-title":"Different effects of unilateral versus bilateral subthalamic nucleus stimulation on walking and reaching in Parkinson's disease","volume":"18","author":"Bastian","year":"2003","journal-title":"Mov Disord"},{"issue":"19","key":"10.1016\/j.brs.2016.06.051_bib0135","doi-asserted-by":"crossref","first-page":"6667","DOI":"10.1523\/JNEUROSCI.5459-09.2010","article-title":"Coupling between beta and high-frequency activity in the human subthalamic nucleus may be a pathophysiological mechanism in Parkinson's disease","volume":"30","author":"L\u00f3pez-Azc\u00e1rate","year":"2010","journal-title":"J Neurosci"},{"issue":"2","key":"10.1016\/j.brs.2016.06.051_bib0140","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jneumeth.2011.03.019","article-title":"Kinematic optimization of deep brain stimulation across multiple motor symptoms in Parkinson's disease","volume":"198","author":"Mera","year":"2011","journal-title":"J Neurosci Methods"},{"issue":"3","key":"10.1016\/j.brs.2016.06.051_bib0145","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1016\/j.neuroimage.2010.10.059","article-title":"Probabilistic analysis of activation volumes generated during deep brain stimulation","volume":"54","author":"Butson","year":"2011","journal-title":"Neuroimage"},{"issue":"6","key":"10.1016\/j.brs.2016.06.051_bib0150","doi-asserted-by":"crossref","first-page":"066012","DOI":"10.1088\/1741-2560\/12\/6\/066012","article-title":"Local field potential recordings in a non-human primate model of Parkinsons disease using the Activa PC\u2009+\u2009S neurostimulator","volume":"12","author":"Connolly","year":"2015","journal-title":"J Neural Eng"},{"issue":"4","key":"10.1016\/j.brs.2016.06.051_bib0155","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1109\/TNSRE.2012.2183617","article-title":"Design and validation of a fully implantable, chronic, closed-loop neuromodulation device with concurrent sensing and stimulation","volume":"20","author":"Stanslaski","year":"2012","journal-title":"IEEE Trans Neural Syst Rehabil Eng"}],"container-title":["Brain Stimulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X16301887?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X16301887?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T22:40:50Z","timestamp":1568068850000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1935861X16301887"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S1935861X16301887"],"URL":"https:\/\/doi.org\/10.1016\/j.brs.2016.06.051","relation":{},"ISSN":["1935-861X"],"issn-type":[{"value":"1935-861X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Closed-Loop Deep Brain Stimulation Effects on Parkinsonian Motor Symptoms in a Non-Human Primate \u2013 Is Beta Enough?","name":"articletitle","label":"Article Title"},{"value":"Brain Stimulation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brs.2016.06.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}