{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T11:18:01Z","timestamp":1790335081121,"version":"4.1.0"},"reference-count":95,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["brainstimjrnl.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Stimulation"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.brs.2019.07.004","type":"journal-article","created":{"date-parts":[[2019,7,6]],"date-time":"2019-07-06T18:00:53Z","timestamp":1562436053000},"page":"1410-1420","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["MR imaging central thalamic deep brain stimulation restored autistic-like social deficits in the rat"],"prefix":"10.1016","volume":"12","author":[{"given":"Ting-Chun","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chun","family":"Lo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Ching","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ssu-Ju","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Huang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Fang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Chia","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Wei","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I-Cheng","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Wen","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin-Chieh","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting-Chieh","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Ju","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen-Yu","family":"Ian Shih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You-Yin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.brs.2019.07.004_bib1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0896-6273(00)00115-X","article-title":"Autism spectrum disorders","volume":"28","author":"Lord","year":"2000","journal-title":"Neuron"},{"key":"10.1016\/j.brs.2019.07.004_bib2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.expneurol.2017.04.017","article-title":"The valproic acid-induced rodent model of autism","volume":"299","author":"Nicolini","year":"2018","journal-title":"Exp Neurol"},{"issue":"4","key":"10.1016\/j.brs.2019.07.004_bib3","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1093\/cercor\/bhx022","article-title":"Homozygous loss of autism-risk gene CNTNAP2 results in reduced local and long-range prefrontal functional connectivity.","volume":"28","author":"Liska","year":"2018","journal-title":"Cereb Cortex"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib4","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1080\/09540261.2018.1458706","article-title":"An update on pharmacotherapy of autism spectrum disorder in children and adolescents","volume":"30","author":"Goel","year":"2018","journal-title":"Int Rev Psychiatry"},{"issue":"6","key":"10.1016\/j.brs.2019.07.004_bib5","first-page":"389","article-title":"Pharmacological therapies for autism spectrum disorder: a review","volume":"40","author":"LeClerc","year":"2015","journal-title":"Pharm Therapeut"},{"issue":"4","key":"10.1016\/j.brs.2019.07.004_bib6","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s40265-013-0021-7","article-title":"Pharmacotherapy for the core symptoms in autistic disorder: current status of the research","volume":"73","author":"Farmer","year":"2013","journal-title":"Drugs"},{"issue":"2","key":"10.1016\/j.brs.2019.07.004_bib7","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.brs.2013.10.004","article-title":"A\u00a0double-blind, randomized trial of deep repetitive transcranial magnetic stimulation (rTMS) for autism spectrum disorder","volume":"7","author":"Enticott","year":"2014","journal-title":"Brain Stimul"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib8","first-page":"e10","article-title":"Transcranial direct current stimulation to the right temporoparietal junction for social functioning in autism spectrum disorder: a case report","volume":"34","author":"Esse Wilson","year":"2018","journal-title":"J\u00a0ECT"},{"issue":"6","key":"10.1016\/j.brs.2019.07.004_bib9","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.brs.2014.10.003","article-title":"The uncertain outcome of prefrontal tDCS","volume":"7","author":"Tremblay","year":"2014","journal-title":"Brain Stimul"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib10","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.cortex.2009.02.020","article-title":"TMS in cognitive neuroscience: virtual lesion and beyond","volume":"46","author":"Ziemann","year":"2010","journal-title":"Cortex"},{"issue":"4","key":"10.1016\/j.brs.2019.07.004_bib11","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.brs.2018.02.005","article-title":"Long-lasting effects of transcranial static magnetic field stimulation on motor cortex excitability","volume":"11","author":"Dileone","year":"2018","journal-title":"Brain Stimul"},{"key":"10.1016\/j.brs.2019.07.004_bib12","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1146\/annurev.neuro.29.051605.112824","article-title":"Deep brain stimulation","volume":"29","author":"Perlmutter","year":"2006","journal-title":"Annu Rev Neurosci"},{"issue":"9","key":"10.1016\/j.brs.2019.07.004_bib13","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/j.parkreldis.2014.06.019","article-title":"Deep brain stimulation for severe secondary stereotypies","volume":"20","author":"Stocco","year":"2014","journal-title":"Park Relat Disord"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib14","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s00701-016-3002-2","article-title":"Nucleus accumbens deep brain stimulation for a patient with self-injurious behavior and autism spectrum disorder: functional and structural changes of the brain: report of a case and review of literature","volume":"159","author":"Park","year":"2017","journal-title":"Acta Neurochir"},{"issue":"7","key":"10.1016\/j.brs.2019.07.004_bib15","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1038\/npp.2015.350","article-title":"High-frequency stimulation at the subthalamic nucleus suppresses excessive self-grooming in autism-like mouse models","volume":"41","author":"Chang","year":"2016","journal-title":"Neuropsychopharmacology : Off Publ Am Coll Neuropsychopharmacol"},{"key":"10.1016\/j.brs.2019.07.004_bib16","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.1749-6632.2009.04534.x","article-title":"Synchrony in the interconnected circuitry of the thalamus and cerebral cortex","volume":"1157","author":"Jones","year":"2009","journal-title":"Ann N Y Acad Sci"},{"issue":"7153","key":"10.1016\/j.brs.2019.07.004_bib17","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/nature06041","article-title":"Behavioural improvements with thalamic stimulation after severe traumatic brain injury","volume":"448","author":"Schiff","year":"2007","journal-title":"Nature"},{"issue":"13","key":"10.1016\/j.brs.2019.07.004_bib18","doi-asserted-by":"crossref","first-page":"R572","DOI":"10.1016\/j.cub.2016.02.027","article-title":"Brain death and disorders of consciousness","volume":"26","author":"Schiff","year":"2016","journal-title":"Curr Biol"},{"key":"10.1016\/j.brs.2019.07.004_bib19","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.09215","article-title":"Frequency-selective control of cortical and subcortical networks by central thalamus","volume":"4","author":"Liu","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.brs.2019.07.004_bib20","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/B978-0-444-53497-2.00024-3","article-title":"Central thalamic deep brain stimulation for support of forebrain arousal regulation in the minimally conscious state","volume":"116","author":"Schiff","year":"2013","journal-title":"Handb Clin Neurol"},{"issue":"3","key":"10.1016\/j.brs.2019.07.004_bib21","first-page":"1964","article-title":"Restoring conscious arousal during focal limbic seizures with deep brain stimulation","volume":"27","author":"Kundishora","year":"2017","journal-title":"Cereb Cortex"},{"issue":"5","key":"10.1016\/j.brs.2019.07.004_bib22","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1152\/jn.01129.2015","article-title":"Robust modulation of arousal regulation, performance, and frontostriatal activity through central thalamic deep brain stimulation in healthy nonhuman primates","volume":"116","author":"Baker","year":"2016","journal-title":"J\u00a0Neurophysiol"},{"issue":"45","key":"10.1016\/j.brs.2019.07.004_bib23","doi-asserted-by":"crossref","first-page":"17007","DOI":"10.1073\/pnas.0604811103","article-title":"Cognitive enhancement with central thalamic electrical stimulation","volume":"103","author":"Shirvalkar","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.brs.2019.07.004_bib24","first-page":"87","article-title":"Central thalamic deep-brain stimulation alters striatal-thalamic connectivity in cognitive neural behavior","volume":"9","author":"Lin","year":"2015","journal-title":"Front Neural Circuits"},{"issue":"3","key":"10.1016\/j.brs.2019.07.004_bib25","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.brs.2017.02.004","article-title":"A\u00a0proof-of-principle simulation for closed-loop control based on preexisting experimental thalamic DBS-enhanced instrumental learning","volume":"10","author":"Wang","year":"2017","journal-title":"Brain Stimul"},{"issue":"4","key":"10.1016\/j.brs.2019.07.004_bib26","first-page":"450","article-title":"Communicating about a social interaction: effects on memory for protagonists' statements and nonverbal behaviors","volume":"40","author":"Adaval","year":"2004","journal-title":"J\u00a0Exp Soc Psychol"},{"issue":"48","key":"10.1016\/j.brs.2019.07.004_bib27","first-page":"2473","article-title":"Assessment of social interaction behaviors","author":"Kaidanovich-Beilin","year":"2011","journal-title":"J\u00a0Vis Exp : J Vis Exp"},{"key":"10.1016\/j.brs.2019.07.004_bib28","series-title":"Encyclopedia of the sciences of learning","first-page":"3104","article-title":"Social interactions and learning","author":"Okita","year":"2012"},{"key":"10.1016\/j.brs.2019.07.004_bib29","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.neubiorev.2015.01.014","article-title":"Limbic circuitry of the midline thalamus","volume":"54","author":"Vertes","year":"2015","journal-title":"Neurosci Biobehav Rev"},{"issue":"7","key":"10.1016\/j.brs.2019.07.004_bib30","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1111\/j.1460-9568.2010.07420.x","article-title":"Central thalamic deep brain stimulation for cognitive neuromodulation\u2013a review of proposed mechanisms and investigational studies","volume":"32","author":"Shah","year":"2010","journal-title":"Eur J Neurosci"},{"issue":"12","key":"10.1016\/j.brs.2019.07.004_bib31","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.biopsych.2013.06.024","article-title":"Centromedian-parafascicular deep brain stimulation induces differential functional inhibition of the motor, associative, and limbic circuits in large animals","volume":"74","author":"Kim","year":"2013","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.brs.2019.07.004_bib32","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.neuroimage.2017.02.019","article-title":"Connectivity-based parcellation reveals distinct cortico-striatal connectivity fingerprints in Autism Spectrum Disorder","volume":"170","author":"Balsters","year":"2018","journal-title":"Neuroimage"},{"key":"10.1016\/j.brs.2019.07.004_bib33","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2016.205","article-title":"Emergence of social behavior deficit, blunted corticolimbic activity and adult depression-like behavior in a rodent model of maternal maltreatment","volume":"6","author":"Rinc\u00f3n-Cort\u00e9s","year":"2016","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.brs.2019.07.004_bib34","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.cobeha.2015.02.004","article-title":"Cellular mechanisms of deep brain stimulation: activity-dependent focal circuit reprogramming?","volume":"4","author":"Veerakumar","year":"2015","journal-title":"Curr Opin Behav Sci"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib35","doi-asserted-by":"crossref","first-page":"7","DOI":"10.31887\/DCNS.2016.18.1\/shaber","article-title":"Corticostriatal circuitry","volume":"18","author":"Haber","year":"2016","journal-title":"Dialogues Clin Neurosci"},{"issue":"14","key":"10.1016\/j.brs.2019.07.004_bib36","doi-asserted-by":"crossref","first-page":"5545","DOI":"10.1523\/JNEUROSCI.18-14-05545.1998","article-title":"Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine","volume":"18","author":"Adams","year":"1998","journal-title":"J\u00a0Neurosci : Off J Soc Neurosci"},{"issue":"20","key":"10.1016\/j.brs.2019.07.004_bib37","doi-asserted-by":"crossref","first-page":"7349","DOI":"10.1523\/JNEUROSCI.6182-10.2011","article-title":"Contrasting roles for dopamine D1 and D2 receptor subtypes in the dorsomedial striatum but not the nucleus accumbens core during behavioral inhibition in the stop-signal task in rats","volume":"31","author":"Eagle","year":"2011","journal-title":"J\u00a0Neurosci"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib38","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.bbr.2010.12.010","article-title":"Contributions of ERK signaling in the striatum to instrumental learning and performance","volume":"218","author":"Shiflett","year":"2011","journal-title":"Behav Brain Res"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib39","doi-asserted-by":"crossref","first-page":"3081","DOI":"10.1038\/s41467-018-05526-5","article-title":"Social interactions impact on the dopaminergic system and drive individuality","volume":"9","author":"Torquet","year":"2018","journal-title":"Nat Commun"},{"issue":"4","key":"10.1016\/j.brs.2019.07.004_bib40","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/nn.3344","article-title":"Deep brain stimulation restores frontostriatal network activity in obsessive-compulsive disorder","volume":"16","author":"Figee","year":"2013","journal-title":"Nat Neurosci"},{"issue":"17","key":"10.1016\/j.brs.2019.07.004_bib41","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1097\/WNR.0b013e32833ce607","article-title":"Chronic pedunculopontine nucleus stimulation restores functional connectivity","volume":"21","author":"Schweder","year":"2010","journal-title":"Neuroreport"},{"issue":"3","key":"10.1016\/j.brs.2019.07.004_bib42","doi-asserted-by":"crossref","first-page":"319","DOI":"10.31887\/DCNS.2012.14.3\/gdichter","article-title":"Functional magnetic resonance imaging of autism spectrum disorders","volume":"14","author":"Dichter","year":"2012","journal-title":"Dialogues Clin Neurosci"},{"issue":"5","key":"10.1016\/j.brs.2019.07.004_bib43","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.neuron.2006.08.012","article-title":"Principles of diffusion tensor imaging and its applications to basic neuroscience research","volume":"51","author":"Mori","year":"2006","journal-title":"Neuron"},{"issue":"7","key":"10.1016\/j.brs.2019.07.004_bib44","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1109\/TBME.2010.2043675","article-title":"Effect of MR distortion on targeting for deep-brain stimulation","volume":"57","author":"Balachandran","year":"2010","journal-title":"IEEE Trans Biomed Eng"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib45","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jneumeth.2009.05.010","article-title":"Design and fabrication of a polyimide-based microelectrode array: application in neural recording and repeatable electrolytic lesion in rat brain","volume":"182","author":"Chen","year":"2009","journal-title":"J\u00a0Neurosci Methods"},{"issue":"6","key":"10.1016\/j.brs.2019.07.004_bib46","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0066821","article-title":"Comparison of fMRI BOLD response patterns by electrical stimulation of the ventroposterior complex and medial thalamus of the rat","volume":"8","author":"Yang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.brs.2019.07.004_bib47","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neuroimage.2013.08.026","article-title":"Functional MRI reveals frequency-dependent responses during deep brain stimulation at the subthalamic nucleus or internal globus pallidus","volume":"84","author":"Lai","year":"2014","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib48","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1080\/09540261.2018.1432574","article-title":"Efficacy of early interventions for infants and young children with, and at risk for, autism spectrum disorders","volume":"30","author":"Landa","year":"2018","journal-title":"Int Rev Psychiatry"},{"key":"10.1016\/j.brs.2019.07.004_bib49","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3389\/fncel.2018.00355","article-title":"Neonatal oxytocin treatment ameliorates autistic-like behaviors and oxytocin deficiency in valproic acid-induced rat model of autism","volume":"12","author":"Dai","year":"2018","journal-title":"Front Cell Neurosci"},{"issue":"3","key":"10.1016\/j.brs.2019.07.004_bib50","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jveb.2012.10.004","article-title":"The use of oral transmucosal detomidine hydrochloride gel to facilitate handling in dogs","volume":"8","author":"Hopfensperger","year":"2013","journal-title":"J\u00a0Vet Behav Clin Appl Res"},{"key":"10.1016\/j.brs.2019.07.004_bib51","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"2007"},{"issue":"3","key":"10.1016\/j.brs.2019.07.004_bib52","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/j.1528-1167.2008.01866.x","article-title":"Lamotrigine\u2013valproic acid combination therapy for medically refractory epilepsy","volume":"50","author":"Moeller","year":"2009","journal-title":"Epilepsia"},{"issue":"23","key":"10.1016\/j.brs.2019.07.004_bib53","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1212\/01.wnl.0000339399.64213.1a","article-title":"Autism spectrum disorders following in utero exposure to antiepileptic drugs","volume":"71","author":"Bromley","year":"2008","journal-title":"Neurology"},{"issue":"03","key":"10.1016\/j.brs.2019.07.004_bib54","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.1469-8749.2001.tb00188.x","article-title":"Fetal valproate syndrome and autism: additional evidence of an association","volume":"43","author":"Williams","year":"2001","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.brs.2019.07.004_bib55","first-page":"1","article-title":"Translational mouse models of autism: advancing toward pharmacological therapeutics","volume":"28","author":"Kazdoba","year":"2016","journal-title":"Curr Top Behav Neurosci"},{"issue":"3","key":"10.1016\/j.brs.2019.07.004_bib56","doi-asserted-by":"crossref","first-page":"293","DOI":"10.31887\/DCNS.2012.14.3\/jcrawley","article-title":"Translational animal models of autism and neurodevelopmental disorders","volume":"14","author":"Crawley","year":"2012","journal-title":"Dialogues Clin Neurosci"},{"issue":"6","key":"10.1016\/j.brs.2019.07.004_bib57","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s10803-006-0117-y","article-title":"A\u00a0new neurobehavioral model of autism in mice: pre- and postnatal exposure to sodium valproate","volume":"36","author":"Wagner","year":"2006","journal-title":"J\u00a0Autism Dev Disord"},{"key":"10.1016\/j.brs.2019.07.004_bib58","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ntt.2013.01.004","article-title":"In utero exposure to valproic acid and autism--a current review of clinical and animal studies","volume":"36","author":"Roullet","year":"2013","journal-title":"Neurotoxicol Teratol"},{"issue":"4","key":"10.1016\/j.brs.2019.07.004_bib59","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1007\/BF00428553","article-title":"Sodium valproate: effects on social behaviour and physical development in the mouse","volume":"83","author":"Chapman","year":"1984","journal-title":"Psychopharmacology (Berl)"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib60","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/sj.npp.1300518","article-title":"Behavioral alterations in rats prenatally exposed to valproic acid: animal model of autism","volume":"30","author":"Schneider","year":"2005","journal-title":"Neuropsychopharmacology : Off Publ Am Coll Neuropsychopharmacol"},{"issue":"4","key":"10.1016\/j.brs.2019.07.004_bib61","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1038\/sj.npp.1301453","article-title":"Abnormal fear conditioning and amygdala processing in an animal model of autism","volume":"33","author":"Markram","year":"2008","journal-title":"Neuropsychopharmacology : Off Publ Am Coll Neuropsychopharmacol"},{"key":"10.1016\/j.brs.2019.07.004_bib62","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/neuro.04.004.2008","article-title":"Hyper-connectivity and hyper-plasticity in the medial prefrontal cortex in the valproic Acid animal model of autism","volume":"2","author":"Rinaldi","year":"2008","journal-title":"Front Neural Circuits"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib63","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1186\/s12906-017-1763-7","article-title":"Postnatal treatment using curcumin supplements to amend the damage in VPA-induced rodent models of autism","volume":"17","author":"Al-Askar","year":"2017","journal-title":"BMC Complement Altern Med"},{"key":"10.1016\/j.brs.2019.07.004_bib64","series-title":"A\u00a0stereotaxic atlas of the developing rat brain","author":"Sherwood","year":"1970"},{"key":"10.1016\/j.brs.2019.07.004_bib65","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.neuroimage.2013.01.017","article-title":"A\u00a0quantitative magnetic resonance histology atlas of postnatal rat brain development with regional estimates of growth and variability","volume":"71","author":"Calabrese","year":"2013","journal-title":"Neuroimage"},{"issue":"4","key":"10.1016\/j.brs.2019.07.004_bib66","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1152\/jn.00989.2003","article-title":"Cellular effects of deep brain stimulation: model-based analysis of activation and inhibition","volume":"91","author":"McIntyre","year":"2004","journal-title":"J\u00a0Neurophysiol"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib67","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.brs.2014.09.017","article-title":"Measurement of evoked potentials during thalamic deep brain stimulation","volume":"8","author":"Kent","year":"2015","journal-title":"Brain Stimul"},{"issue":"4","key":"10.1016\/j.brs.2019.07.004_bib68","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1002\/mrdd.20039","article-title":"Designing mouse behavioral tasks relevant to autistic-like behaviors","volume":"10","author":"Crawley","year":"2004","journal-title":"Ment Retard Dev Disabil Res Rev"},{"issue":"349","key":"10.1016\/j.brs.2019.07.004_bib69","article-title":"An open-source toolbox for automated phenotyping of mice in behavioral tasks","volume":"8","author":"Patel","year":"2014","journal-title":"Front Behav Neurosci"},{"issue":"2","key":"10.1016\/j.brs.2019.07.004_bib70","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s00429-011-0345-6","article-title":"Collateral projections from nucleus reuniens of thalamus to hippocampus and medial prefrontal cortex in the rat: a single and double retrograde fluorescent labeling study","volume":"217","author":"Hoover","year":"2012","journal-title":"Brain Struct Funct"},{"issue":"83","key":"10.1016\/j.brs.2019.07.004_bib71","article-title":"Intralaminar and medial thalamic influence on cortical synchrony, information transmission and cognition","volume":"8","author":"Saalmann","year":"2014","journal-title":"Front Syst Neurosci"},{"issue":"3","key":"10.1016\/j.brs.2019.07.004_bib72","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0891-0618(99)00010-1","article-title":"Thalamic interaction between the input and the output systems of the basal ganglia","volume":"16","author":"Mengual","year":"1999","journal-title":"J\u00a0Chem Neuroanat"},{"issue":"3","key":"10.1016\/j.brs.2019.07.004_bib73","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/0306-4522(96)00001-2","article-title":"Striatal and cortical projections of single neurons from the central lateral thalamic nucleus in the rat","volume":"72","author":"Desch\u00eanes","year":"1996","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.brs.2019.07.004_bib74","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1037\/1064-1297.16.3.191","article-title":"Increased amygdala fMRI activation after secretin administration","volume":"16","author":"Yurgelun-Todd","year":"2008","journal-title":"Exp Clin Psychopharmacol"},{"issue":"1","key":"10.1016\/j.brs.2019.07.004_bib75","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1196\/annals.1417.029","article-title":"Central thalamic contributions to arousal regulation and neurological disorders of consciousness","volume":"1129","author":"Schiff","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.brs.2019.07.004_bib76","first-page":"1031","article-title":"Social cognitive and neurocognitive deficits in inpatients with unilateral thalamic lesions - pilot study","volume":"11","author":"Wilkos","year":"2015","journal-title":"Neuropsychiatric Dis Treat"},{"issue":"11","key":"10.1016\/j.brs.2019.07.004_bib77","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.jaac.2015.08.010","article-title":"Atypical learning in autism spectrum disorders: a functional magnetic resonance imaging study of transitive inference","volume":"54","author":"Solomon","year":"2015","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"issue":"7657","key":"10.1016\/j.brs.2019.07.004_bib78","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1038\/nature22381","article-title":"Dynamic corticostriatal activity biases social bonding in monogamous female prairie voles","volume":"546","author":"Amadei","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.brs.2019.07.004_bib79","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3389\/fnins.2016.00027","article-title":"Striatal circuits as a common node for autism pathophysiology","volume":"10","author":"Fuccillo","year":"2016","journal-title":"Front Neurosci"},{"key":"10.1016\/j.brs.2019.07.004_bib80","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1749-6632.2008.04123.x","article-title":"Central thalamic deep-brain stimulation in the severely injured brain: rationale and proposed mechanisms of action","volume":"1157","author":"Schiff","year":"2009","journal-title":"Ann N Y Acad Sci"},{"issue":"3","key":"10.1016\/j.brs.2019.07.004_bib81","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.biopsych.2009.07.037","article-title":"Dopamine type 2\/3 receptor availability in the striatum and social status in human volunteers","volume":"67","author":"Martinez","year":"2010","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.brs.2019.07.004_bib82","doi-asserted-by":"crossref","first-page":"43348","DOI":"10.1038\/srep43348","article-title":"The roles of dopamine D2 receptor in the social hierarchy of rodents and primates","volume":"7","author":"Yamaguchi","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.brs.2019.07.004_bib83","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1744-9081-8-19","article-title":"DRD2 and PPP1R1B (DARPP-32) polymorphisms independently confer increased risk for autism spectrum disorders and additively predict affected status in male-only affected sib-pair families","volume":"8","author":"Hettinger","year":"2012","journal-title":"Behav Brain Funct"},{"issue":"8","key":"10.1016\/j.brs.2019.07.004_bib84","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1038\/sj.emboj.7601656","article-title":"Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor","volume":"26","author":"Lee","year":"2007","journal-title":"EMBO J"},{"issue":"4","key":"10.1016\/j.brs.2019.07.004_bib85","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1046\/j.0953-816x.2000.01443.x","article-title":"Dopamine D(2) receptors regulate tyrosine hydroxylase activity and phosphorylation at Ser40 in rat striatum","volume":"13","author":"Lindgren","year":"2001","journal-title":"Eur J Neurosci"},{"issue":"2","key":"10.1016\/j.brs.2019.07.004_bib86","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1038\/sj.npp.1300825","article-title":"Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting","volume":"31","author":"Floresco","year":"2006","journal-title":"Neuropsychopharmacology : Off Publ Am Coll Neuropsychopharmacol"},{"key":"10.1016\/j.brs.2019.07.004_bib87","doi-asserted-by":"crossref","first-page":"e427","DOI":"10.1038\/tp.2014.69","article-title":"Dysfunctional dopaminergic neurotransmission in asocial BTBR mice","volume":"4","author":"Squillace","year":"2014","journal-title":"Transl Psychiatry"},{"issue":"7","key":"10.1016\/j.brs.2019.07.004_bib88","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0102576","article-title":"Time and frequency-dependent modulation of local field potential synchronization by deep brain stimulation","volume":"9","author":"McCracken","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.brs.2019.07.004_bib89","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/jnc.13649","article-title":"Deep brain stimulation mechanisms: the control of network activity via neurochemistry modulation","volume":"139","author":"McIntyre","year":"2016","journal-title":"J\u00a0Neurochem"},{"key":"10.1016\/j.brs.2019.07.004_bib90","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3389\/fncir.2014.00069","article-title":"Thalamic neuromodulation and its implications for executive networks","volume":"8","author":"Varela","year":"2014","journal-title":"Front Neural Circuits"},{"issue":"6","key":"10.1016\/j.brs.2019.07.004_bib91","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1096\/fj.201600755RR","article-title":"Functional expression of dopamine D2 receptor is regulated by tetraspanin 7-mediated postendocytic trafficking","volume":"31","author":"Lee","year":"2017","journal-title":"FASEB J : Off Publ Fed Am Soc Exp Biol"},{"issue":"9","key":"10.1016\/j.brs.2019.07.004_bib92","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.biopsych.2010.10.029","article-title":"Aberrant striatal functional connectivity in children with autism","volume":"69","author":"Di Martino","year":"2011","journal-title":"Biol Psychiatry"},{"issue":"27","key":"10.1016\/j.brs.2019.07.004_bib93","doi-asserted-by":"crossref","first-page":"9402","DOI":"10.1523\/JNEUROSCI.1180-12.2012","article-title":"Dopamine, corticostriatal connectivity, and intertemporal choice","volume":"32","author":"Kayser","year":"2012","journal-title":"J\u00a0Neurosci"},{"issue":"6","key":"10.1016\/j.brs.2019.07.004_bib94","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/S1734-1140(12)70927-1","article-title":"Drug therapy in autism: a present and future perspective","volume":"64","author":"Kumar","year":"2012","journal-title":"Pharmacol Rep : PR"},{"key":"10.1016\/j.brs.2019.07.004_bib95","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3389\/fpsyt.2016.00078","article-title":"Cortico-striato-thalamo-cortical circuitry, working memory, and obsessive\u2013compulsive disorder","volume":"7","author":"Li","year":"2016","journal-title":"Front Psychiatry"}],"container-title":["Brain Stimulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X19302888?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X19302888?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T14:13:27Z","timestamp":1761833607000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1935861X19302888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":95,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["S1935861X19302888"],"URL":"https:\/\/doi.org\/10.1016\/j.brs.2019.07.004","relation":{},"ISSN":["1935-861X"],"issn-type":[{"value":"1935-861X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MR imaging central thalamic deep brain stimulation restored autistic-like social deficits in the rat","name":"articletitle","label":"Article Title"},{"value":"Brain Stimulation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brs.2019.07.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}