{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:15:21Z","timestamp":1792804521772,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T00:00:00Z","timestamp":1629331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007397","name":"Univerzita Karlova v Praze","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MC_UU_12024\/1"],"award-info":[{"award-number":["MC_UU_12024\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["424778381 \u2013 TRR 295"],"award-info":[{"award-number":["424778381 \u2013 TRR 295"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001823","name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy","doi-asserted-by":"publisher","award":["NV19-04-00233"],"award-info":[{"award-number":["NV19-04-00233"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["FKZ01GQ1802"],"award-info":[{"award-number":["FKZ01GQ1802"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["brainstimjrnl.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Stimulation"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.brs.2021.08.016","type":"journal-article","created":{"date-parts":[[2021,8,21]],"date-time":"2021-08-21T11:01:32Z","timestamp":1629543692000},"page":"1301-1306","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":92,"title":["The sensitivity of ECG contamination to surgical implantation site in brain computer interfaces"],"prefix":"10.1016","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6758-9708","authenticated-orcid":false,"given":"Wolf-Julian","family":"Neumann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid","family":"Memarian Sorkhabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moaad","family":"Benjaber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1290-208X","authenticated-orcid":false,"given":"Lucia K.","family":"Feldmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assel","family":"Saryyeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim K.","family":"Krauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0312-184X","authenticated-orcid":false,"given":"Maria Fiorella","family":"Contarino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4960-1934","authenticated-orcid":false,"given":"Tomas","family":"Sieger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Jech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1954-1873","authenticated-orcid":false,"given":"Gerd","family":"Tinkhauser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Pollo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Palmisano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis U.","family":"Isaias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2742-5669","authenticated-orcid":false,"given":"Daniel D.","family":"Cummins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon J.","family":"Little","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip A.","family":"Starr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4309-5455","authenticated-orcid":false,"given":"Vasileios","family":"Kokkinos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Schneider","family":"Gerd-Helge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd","family":"Herrington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5201-3044","authenticated-orcid":false,"given":"Peter","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Mark","family":"Richardson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea A.","family":"K\u00fchn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Denison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brs.2021.08.016_bib1","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1038\/s41587-019-0244-6","article-title":"Emerging technologies for improved deep brain stimulation","volume":"37","author":"Cagnan","year":"2019","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.brs.2021.08.016_bib2","article-title":"Technology of deep brain stimulation: current status and future directions","author":"Krauss","year":"2020","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.brs.2021.08.016_bib3","doi-asserted-by":"crossref","DOI":"10.1002\/ana.23951","article-title":"Adaptive deep brain stimulation in advanced Parkinson disease","author":"Little","year":"2013","journal-title":"Ann Neurol"},{"key":"10.1016\/j.brs.2021.08.016_bib4","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.0000000000005121","article-title":"Eight-hours adaptive deep brain stimulation in patients with Parkinson disease","author":"Arlotti","year":"2018","journal-title":"Neurology"},{"key":"10.1016\/j.brs.2021.08.016_bib5","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1002\/mds.27022","article-title":"Adaptive deep brain stimulation for movement disorders: the long road to clinical therapy","volume":"32","author":"Meidahl","year":"2017","journal-title":"Mov Disord"},{"key":"10.1016\/j.brs.2021.08.016_bib6","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.neuron.2011.08.023","article-title":"Closed-loop deep brain stimulation is superior in ameliorating parkinsonism","volume":"72","author":"Rosin","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.brs.2021.08.016_bib7","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1002\/mds.26759","article-title":"Subthalamic synchronized oscillatory activity correlates with motor impairment in patients with Parkinson's disease","volume":"31","author":"Neumann","year":"2016","journal-title":"Mov Disord"},{"key":"10.1016\/j.brs.2021.08.016_bib8","doi-asserted-by":"crossref","DOI":"10.1111\/j.1460-9568.2006.04717.x","article-title":"Reduction in subthalamic 8-35 Hz oscillatory activity correlates with clinical improvement in Parkinson's disease","volume":"23","author":"Kuhn","year":"2006","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.brs.2021.08.016_bib9","article-title":"Modulation of beta bursts in subthalamic sensorimotor circuits predicts improvement in bradykinesia","author":"Kehnemouyi","year":"2020","journal-title":"Brain"},{"key":"10.1016\/j.brs.2021.08.016_bib10","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1136\/jnnp.2010.217489","article-title":"Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients","volume":"82","author":"Eusebio","year":"2011","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.brs.2021.08.016_bib11","doi-asserted-by":"crossref","first-page":"6165","DOI":"10.1523\/JNEUROSCI.0282-08.2008","article-title":"High-frequency stimulation of the subthalamic nucleus suppresses oscillatory beta activity in patients with Parkinson's disease in parallel with improvement in motor performance","volume":"28","author":"K\u00fchn","year":"2008","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.brs.2021.08.016_bib12","doi-asserted-by":"crossref","DOI":"10.1007\/s13311-018-00705-0","article-title":"Toward electrophysiology-based intelligent adaptive deep brain stimulation for movement disorders","volume":"16","author":"Neumann","year":"2019","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.brs.2021.08.016_bib13","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1001\/jamaneurol.2019.0658","article-title":"Association of closed-loop brain stimulation neurophysiological features with seizure control among patients with focal epilepsy","volume":"76","author":"Kokkinos","year":"2019","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.brs.2021.08.016_bib14","doi-asserted-by":"crossref","DOI":"10.1007\/s13311-018-00705-0","article-title":"Toward electrophysiology-based intelligent adaptive deep brain stimulation for movement disorders","author":"Neumann","year":"2019","journal-title":"Neurotherapeutics"},{"issue":"1","key":"10.1016\/j.brs.2021.08.016_bib15","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/mds.26703","article-title":"Innovations in deep brain stimulation methodology","volume":"32","author":"K\u00fchn","year":"2017","journal-title":"Mov Disord"},{"key":"10.1016\/j.brs.2021.08.016_bib16","doi-asserted-by":"crossref","DOI":"10.1109\/TBME.1984.325237","article-title":"From holter monitors to automatic defibrillators: developments in ambulatory arrhythmia monitoring","author":"Thakor","year":"1984","journal-title":"IEEE Trans Biomed Eng"},{"key":"10.1016\/j.brs.2021.08.016_bib17","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.nbd.2018.09.004","article-title":"Neuromodulation targets pathological not physiological beta bursts during gait in Parkinson's disease","volume":"120","author":"Anidi","year":"2018","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.brs.2021.08.016_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.clinph.2017.08.028","article-title":"Long term correlation of subthalamic beta band activity with motor impairment in patients with Parkinson's disease","author":"Neumann","year":"2017","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.brs.2021.08.016_bib19","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1109\/TNSRE.2012.2183617","article-title":"Design and validation of a fully implantable, chronic, closed-loop neuromodulation device with concurrent sensing and stimulation","volume":"20","author":"Stanslaski","year":"2012","journal-title":"IEEE Trans Neural Syst Rehabil Eng"},{"key":"10.1016\/j.brs.2021.08.016_bib20","series-title":"Physiological artifacts and the implications for brain-machine-interface design","author":"Sorkhabi","year":"2020"},{"key":"10.1016\/j.brs.2021.08.016_bib21","series-title":"5.6 - the electrocardiogram. Quant. Hum. Physiol. An introd.","first-page":"467","author":"Feher","year":"2012"},{"key":"10.1016\/j.brs.2021.08.016_bib22","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1002\/clc.4960151013","article-title":"Single moving dipole obtained from magnetic field of the heart in patients with left ventricular hypertrophy","volume":"15","author":"Nomura","year":"1992","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.brs.2021.08.016_bib23","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1002\/ana.25095","article-title":"A\u00a0localized pallidal physiomarker in cervical dystonia","volume":"82","author":"Neumann","year":"2017","journal-title":"Ann Neurol"},{"key":"10.1016\/j.brs.2021.08.016_bib24","doi-asserted-by":"crossref","DOI":"10.1002\/mds.25078","article-title":"Enhanced low-frequency oscillatory activity of the subthalamic nucleus in a patient with dystonia","volume":"27","author":"Neumann","year":"2012","journal-title":"Mov Disord"},{"key":"10.1016\/j.brs.2021.08.016_bib25","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.brs.2019.02.011","article-title":"Decoding voluntary movements and postural tremor based on thalamic LFPs as a basis for closed-loop stimulation for essential tremor","volume":"12","author":"Tan","year":"2019","journal-title":"Brain Stimul"},{"key":"10.1016\/j.brs.2021.08.016_bib26","doi-asserted-by":"crossref","DOI":"10.1002\/ana.25311","article-title":"Pallidal and thalamic neural oscillatory patterns in Tourette syndrome","author":"Neumann","year":"2018","journal-title":"Ann Neurol"},{"key":"10.1016\/j.brs.2021.08.016_bib27","article-title":"Report of a patient undergoing chronic responsive deep brain stimulation for Tourette syndrome: proof of concept","volume":"1\u20137","author":"Molina","year":"2017","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.brs.2021.08.016_bib28","doi-asserted-by":"crossref","DOI":"10.1038\/mp.2014.2","article-title":"Different patterns of local field potentials from limbic DBS targets in patients with major depressive and obsessive compulsive disorder","volume":"19","author":"Neumann","year":"2014","journal-title":"Mol Psychiatr"},{"key":"10.1016\/j.brs.2021.08.016_bib29","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1002\/ana.25234","article-title":"Subthalamic nucleus deep brain stimulation evokes resonant neural activity","volume":"83","author":"Sinclair","year":"2018","journal-title":"Ann Neurol"},{"key":"10.1016\/j.brs.2021.08.016_bib30","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2552\/aabc9b","article-title":"Adaptive deep brain stimulation for Parkinson's disease using motor cortex sensing","author":"Swann","year":"2018","journal-title":"J\u00a0Neural Eng"},{"key":"10.1016\/j.brs.2021.08.016_bib31","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aay7680","article-title":"Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor","volume":"12","author":"Opri","year":"2020","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.brs.2021.08.016_bib32","first-page":"1","article-title":"Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson's disease","author":"Gilron","year":"2021","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.brs.2021.08.016_bib33","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2552\/aae67f","article-title":"A\u00a0machine-learning approach to volitional control of a closed-loop deep brain stimulation system","volume":"16","author":"Houston","year":"2019","journal-title":"J\u00a0Neural Eng"},{"key":"10.1016\/j.brs.2021.08.016_bib34","doi-asserted-by":"crossref","first-page":"113825","DOI":"10.1016\/j.expneurol.2021.113825","article-title":"Embedded adaptive deep brain stimulation for cervical dystonia controlled by motor cortex theta oscillations","author":"Johnson","year":"2021","journal-title":"Exp Neurol"},{"key":"10.1016\/j.brs.2021.08.016_bib35","first-page":"226","article-title":"Removal of electrocardiogram artifacts from local field potentials recorded by sensing-enabled neurostimulator","volume":"15","author":"Chen","year":"2021","journal-title":"Front Neurosci"}],"container-title":["Brain Stimulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X21002187?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X21002187?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T14:19:19Z","timestamp":1761833959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1935861X21002187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S1935861X21002187"],"URL":"https:\/\/doi.org\/10.1016\/j.brs.2021.08.016","relation":{},"ISSN":["1935-861X"],"issn-type":[{"value":"1935-861X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The sensitivity of ECG contamination to surgical implantation site in brain computer interfaces","name":"articletitle","label":"Article Title"},{"value":"Brain Stimulation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brs.2021.08.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}