{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T15:28:12Z","timestamp":1790954892380,"version":"4.1.0"},"reference-count":68,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,28]],"date-time":"2021-11-28T00:00:00Z","timestamp":1638057600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["brainstimjrnl.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Stimulation"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.brs.2021.11.019","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T14:17:20Z","timestamp":1638281840000},"page":"152-163","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":53,"title":["Phase- targeted stimulation modulates phase-amplitude coupling in the motor cortex of the human brain"],"prefix":"10.1016","volume":"15","author":[{"given":"Yousef","family":"Salimpour","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4302-1501","authenticated-orcid":false,"given":"Kelly A.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian Y.","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William S.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.brs.2021.11.019_bib1","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.tics.2010.09.001","article-title":"The functional role of cross-frequency coupling","volume":"14","author":"Canolty","year":"2010","journal-title":"Trends Cognit Sci"},{"issue":"11","key":"10.1016\/j.brs.2021.11.019_bib2","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.tins.2015.09.001","article-title":"Neural cross-frequency coupling: connecting architectures, mechanisms, and functions","volume":"38","author":"Hyafil","year":"2015","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.brs.2021.11.019_bib3","doi-asserted-by":"crossref","first-page":"5614","DOI":"10.1073\/pnas.1719433115","article-title":"A\u00a0theta rhythm in macaque visual cortex and its attentional modulation","volume":"115","author":"Spyropoulos","year":"2018","journal-title":"Proc Natl Acad Sci Unit States Am"},{"key":"10.1016\/j.brs.2021.11.019_bib4","doi-asserted-by":"crossref","first-page":"487","DOI":"10.3389\/fnins.2017.00487","article-title":"The detection of phase Amplitude coupling during sensory processing","volume":"11","author":"Seymour","year":"2017","journal-title":"Front Neurosci"},{"key":"10.1016\/j.brs.2021.11.019_bib5","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.neuroscience.2017.08.058","article-title":"Home-cage odors spatial cues elicit theta phase\/gamma amplitude coupling between olfactory bulb and dorsal hippocampus","volume":"363","author":"Pena","year":"2017","journal-title":"Neuroscience"},{"issue":"4","key":"10.1016\/j.brs.2021.11.019_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.2000219","article-title":"Sequence learning modulates neural responses and oscillatory coupling in human and monkey auditory cortex","volume":"15","author":"Kikuchi","year":"2017","journal-title":"PLoS Biol"},{"issue":"2","key":"10.1016\/j.brs.2021.11.019_bib7","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.neulet.2011.05.037","article-title":"Phase\u2013amplitude coupling between theta and gamma oscillations during nociception in rat electroencephalography","volume":"499","author":"Wang","year":"2011","journal-title":"Neurosci Lett"},{"issue":"10","key":"10.1016\/j.brs.2021.11.019_bib67","doi-asserted-by":"crossref","first-page":"3854","DOI":"10.1002\/hbm.24216","article-title":"Gating by induced \u0391\u2013\u0393 asynchrony in selective attention","volume":"39","author":"Pascucci","year":"2018","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.brs.2021.11.019_bib8","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/j.neuron.2013.03.007","article-title":"The \u03b8-\u03b3 neural code","volume":"77","author":"Lisman","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.brs.2021.11.019_bib9","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1152\/physrev.00035.2008","article-title":"Neurophysiological and computational principles of cortical rhythms in Cognition","volume":"90","author":"Wang","year":"2010","journal-title":"Physiol Rev"},{"key":"10.1016\/j.brs.2021.11.019_bib10","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3389\/fnsys.2011.00059","article-title":"Components of cross-frequency modulation in health and disease","volume":"5","author":"Allen","year":"2011","journal-title":"Front Syst Neurosci"},{"issue":"10","key":"10.1016\/j.brs.2021.11.019_bib11","article-title":"Alterations in hippocampal network oscillations and theta-gamma coupling arise before A\u03b2 overproduction in a mouse model of Alzheimer's disease","volume":"38","author":"Goutagny","year":"2013","journal-title":"Europ. J. Neurosci. Eur J Neurosci"},{"issue":"12","key":"10.1016\/j.brs.2021.11.019_bib12","doi-asserted-by":"crossref","first-page":"4780","DOI":"10.1073\/pnas.1214546110","article-title":"Exaggerated phase\u2013amplitude coupling in the primary motor cortex in Parkinson disease","volume":"110","author":"De Hemptinne","year":"2013","journal-title":"Proc Natl Acad Sci Unit States Am"},{"issue":"9","key":"10.1016\/j.brs.2021.11.019_bib13","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1016\/j.clinph.2017.05.020","article-title":"Temporal-spatial characteristics of phase-amplitude coupling in electrocorticogram for human temporal lobe epilepsy","volume":"128","author":"Zhang","year":"2017","journal-title":"Clin Neurophysiol"},{"issue":"1","key":"10.1016\/j.brs.2021.11.019_bib14","first-page":"69","article-title":"Phase-amplitude coupling of the electroencephalogram in the auditory cortex in schizophrenia","volume":"3","author":"Hirano","year":"2018","journal-title":"Biol Psychiatr: Cognitive Neurosci. Neuroimag."},{"issue":"17","key":"10.1016\/j.brs.2021.11.019_bib15","doi-asserted-by":"crossref","first-page":"4535","DOI":"10.1523\/JNEUROSCI.5297-05.2006","article-title":"Neocortical network activity in\u00a0vivo is generated through a dynamic balance of excitation and inhibition","volume":"26","author":"Haider","year":"2006","journal-title":"J\u00a0Neurosci"},{"issue":"5","key":"10.1016\/j.brs.2021.11.019_bib16","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1093\/schbul\/sbn060","article-title":"A\u00a0neural coding scheme formed by the combined function of gamma and theta oscillations","volume":"34","author":"Lisman","year":"2008","journal-title":"Schizophr Bull"},{"issue":"5","key":"10.1016\/j.brs.2021.11.019_bib17","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1002\/ana.24507","article-title":"Elevated synchrony in Parkinson disease detected with electroencephalography","volume":"78","author":"Swann","year":"2015","journal-title":"Ann Neurol"},{"issue":"1","key":"10.1016\/j.brs.2021.11.019_bib18","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1152\/jn.00141.2019","article-title":"Effect of levodopa on electroencephalographic biomarkers of the parkinsonian state","volume":"122","author":"Miller","year":"2019","journal-title":"J\u00a0Neurophysiol"},{"issue":"5","key":"10.1016\/j.brs.2021.11.019_bib19","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1038\/nn.3997","article-title":"Therapeutic deep brain stimulation reduces cortical phase-amplitude coupling in Parkinson's disease","volume":"18","author":"De Hemptinne","year":"2015","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.brs.2021.11.019_bib20","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0006-8993(88)91499-0","article-title":"Long-term potentiation in the dentate gyrus is induced preferentially on the positive phase of \u03b8-rhythm","volume":"439","author":"Pavlides","year":"1988","journal-title":"Brain Res"},{"key":"10.1016\/j.brs.2021.11.019_bib21","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/364723a0","article-title":"Heightened synaptic plasticity of hippocampal CA1 neurons during a cholinergically induced rhythmic state","volume":"364","author":"Huerta","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.brs.2021.11.019_bib22","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/0896-6273(95)90094-2","article-title":"Bidirectional synaptic plasticity induced by a single burst during cholinergic theta oscillation in CA1 in\u00a0vitro","volume":"15","author":"Huerta","year":"1995","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.brs.2021.11.019_bib23","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/hipo.450010206","article-title":"Learning-related patterns of CA1 spike trains parallel stimulation parameters optimal for inducing hippocampal long-term potentiation","volume":"1","author":"Otto","year":"1991","journal-title":"Hippocampus"},{"key":"10.1016\/j.brs.2021.11.019_bib24","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/0006-8993(92)90986-J","article-title":"Effects of atropine on hippocampal theta cells and complex-spike cells","volume":"591","author":"Stewart","year":"1992","journal-title":"Brain Res"},{"key":"10.1016\/j.brs.2021.11.019_bib25","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1097\/00001756-199511000-00017","article-title":"Medial septal control of theta-correlated unit firing in the entorhinal cortex of awake rats","volume":"6","author":"Jeffery","year":"1996","journal-title":"Neuroreport"},{"key":"10.1016\/j.brs.2021.11.019_bib26","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.03061","article-title":"Enhancement of encoding and retrieval functions through theta phase-specific manipulation of hippocampus","volume":"3","author":"Siegle","year":"2014","journal-title":"Elife"},{"key":"10.1016\/j.brs.2021.11.019_bib27","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1146\/annurev.neuro.23.1.649","article-title":"Synaptic plasticity and memory: an evaluation of the hypothesis","volume":"23","author":"Martin","year":"2000","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.brs.2021.11.019_bib28","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1038\/nrn2234","article-title":"Synaptic plasticity and addiction","volume":"8","author":"Kauer","year":"2007","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.brs.2021.11.019_bib29","first-page":"22","article-title":"STDP in oscillatory recurrent networks: theoretical conditions for desynchronization and applications to deep-brain stimulation","volume":"4","author":"Pfister","year":"2010","journal-title":"Front Comput Neurosci"},{"issue":"30","key":"10.1016\/j.brs.2021.11.019_bib30","doi-asserted-by":"crossref","first-page":"5833","DOI":"10.1523\/JNEUROSCI.1996-19.2020","article-title":"Synchrony drives motor cortex beta bursting, waveform dynamics, and phase-amplitude coupling in Parkinson's disease","volume":"40","author":"O'Keeffe","year":"2020","journal-title":"J\u00a0Neurosci"},{"issue":"8","key":"10.1016\/j.brs.2021.11.019_bib31","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1016\/j.celrep.2020.02.005","article-title":"Phase-specific microstimulation differentially modulates beta oscillations and affects behavior","volume":"30","author":"Peles","year":"2020","journal-title":"Cell Rep"},{"issue":"6","key":"10.1016\/j.brs.2021.11.019_bib32","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1016\/j.brs.2020.09.017","article-title":"Real-time suppression and amplification of frequency-specific neural activity using stimulation evoked oscillations","volume":"13","author":"Sanabria","year":"2020","journal-title":"Brain Stimulation"},{"key":"10.1016\/j.brs.2021.11.019_bib33","first-page":"3087","article-title":"A\u00a0method for real-time cortical oscillation detection and phase-locked stimulation","volume":"2011","author":"Chen","year":"2011","journal-title":"Conf Proc IEEE Eng Med Biol Soc"},{"issue":"3","key":"10.1016\/j.brs.2021.11.019_bib34","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1109\/TBME.2011.2109715","article-title":"Real-time brain oscillation detection and phase-locked stimulation using autoregressive spectral estimation and forward prediction","volume":"60","author":"Chen","year":"2013","journal-title":"IEEE Trans Biomed Eng"},{"issue":"6","key":"10.1016\/j.brs.2021.11.019_bib35","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1523\/JNEUROSCI.1913-18.2018","article-title":"Phase-dependent suppression of beta oscillations in Parkinson's disease patients","volume":"39","author":"Holt","year":"2019","journal-title":"J\u00a0Neurosci"},{"issue":"2","key":"10.1016\/j.brs.2021.11.019_bib36","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.brs.2017.11.016","article-title":"Real-time EEG-defined excitability states determine efficacy of TMS-induced plasticity in human motor cortex","volume":"11","author":"Zrenner","year":"2018","journal-title":"Brain Stimul"},{"key":"10.1016\/j.brs.2021.11.019_bib37","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3389\/fnins.2019.00125","article-title":"Cross-frequency coupling based neuromodulation for treating neurological disorders","volume":"13","author":"Salimpour","year":"2019","journal-title":"Front Neurosci"},{"issue":"4","key":"10.1016\/j.brs.2021.11.019_bib38","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1002\/1531-8257(199907)14:4<572::AID-MDS1005>3.0.CO;2-C","article-title":"Core assessment program for surgical interventional therapies in Parkinson's disease (CAPSIT-PD). Movement disorders","volume":"14","author":"Defer","year":"1999","journal-title":"Offic J Move Dis Soc"},{"key":"10.1016\/j.brs.2021.11.019_bib39","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1093\/brain\/awr332","article-title":"Oscillations in sensorimotor cortex in movement disorders: an electrocorticography study","volume":"135","author":"Crowell","year":"2012","journal-title":"Brain"},{"issue":"8","key":"10.1016\/j.brs.2021.11.019_bib40","doi-asserted-by":"crossref","first-page":"3508","DOI":"10.1093\/cercor\/bhw157","article-title":"The human brainnetome atlas: a new brain atlas based on connectional architecture","volume":"26","author":"Fan","year":"2016","journal-title":"Cerebr Cortex"},{"issue":"7","key":"10.1016\/j.brs.2021.11.019_bib41","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1038\/s41596-018-0009-6","article-title":"Integrated analysis of anatomical and electrophysiological human intracranial data","volume":"13","author":"Stolk","year":"2018","journal-title":"Nat Protoc"},{"key":"10.1016\/j.brs.2021.11.019_bib42","first-page":"1","article-title":"Decrease in gamma-band activity tracks sequence learning","volume":"8","author":"Madhaven","year":"2015","journal-title":"Front Syst Neurosci"},{"issue":"2","key":"10.1016\/j.brs.2021.11.019_bib43","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1152\/jn.00106.2010","article-title":"Measuring phase-amplitude coupling between neuronal oscillations of different frequencies","volume":"104","author":"Tort","year":"2010","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.brs.2021.11.019_bib44","doi-asserted-by":"crossref","first-page":"20517","DOI":"10.1073\/pnas.0810524105","article-title":"Dynamic cross-frequency couplings of local field potential oscillations in rat striatum and hippocampus during performance of a T-maze task","volume":"105","author":"Tort","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"issue":"49","key":"10.1016\/j.brs.2021.11.019_bib45","doi-asserted-by":"crossref","first-page":"20942","DOI":"10.1073\/pnas.0911331106","article-title":"Theta-gamma coupling increases during the learning of item-context associations","volume":"106","author":"Tort","year":"2009","journal-title":"Proc Natl Acad Sci Unit States Am"},{"key":"10.1016\/j.brs.2021.11.019_bib46","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1152\/jn.00853.2003","article-title":"Statistical method for detection of phase-locking episodes in neural oscillations","volume":"91","author":"Hurtado","year":"2004","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.brs.2021.11.019_bib47","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.conb.2018.01.012","article-title":"Toward true closed-loop neuromodulation: artifact-free recording during stimulation","volume":"50","author":"Zhou","year":"2018","journal-title":"Curr Op Neurobiol"},{"key":"10.1016\/j.brs.2021.11.019_bib48","first-page":"718","article-title":"Particle filtering of point processes observation with application on the modeling of visual cortex neural spiking activity","author":"Salimpour","year":"2009","journal-title":"4th Int. IEEE\/EMBS Conf. Neural Eng."},{"issue":"5","key":"10.1016\/j.brs.2021.11.019_bib49","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2552\/ab2214","article-title":"Dynamic network modeling and dimensionality reduction for human ECoG activity","volume":"16","author":"Yang","year":"2019","journal-title":"J\u00a0Neural Eng"},{"issue":"5","key":"10.1016\/j.brs.2021.11.019_bib50","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1109\/10.668741","article-title":"Adaptive AR modeling of nonstationary time series by means of Kalman filtering","volume":"45","author":"Arnold","year":"1998","journal-title":"IEEE Trans Biomed Eng"},{"issue":"18","key":"10.1016\/j.brs.2021.11.019_bib72","doi-asserted-by":"crossref","first-page":"4830","DOI":"10.1523\/JNEUROSCI.2208-16.2017","article-title":"Nonsinusoidal beta oscillations reflect cortical pathophysiology in Parkinson\u2019s disease","volume":"37","author":"Cole","year":"2017","journal-title":"J\u00a0Neurosci"},{"issue":"1","key":"10.1016\/j.brs.2021.11.019_bib73","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.eplepsyres.2008.12.005","article-title":"Phase-dependent stimulation effects on bursting activity in a neural network cortical simulation","volume":"84","author":"Anderson","year":"2009","journal-title":"Epilepsy Res"},{"issue":"6","key":"10.1016\/j.brs.2021.11.019_bib51","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1109\/TAC.1974.1100705","article-title":"A\u00a0new look at the statistical model identification","volume":"19","author":"Akaike","year":"1974","journal-title":"IEEE Trans Automat Control"},{"issue":"4","key":"10.1016\/j.brs.2021.11.019_bib52","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1111\/biom.12889","article-title":"A\u00a0boxplot for circular data","volume":"74","author":"Buttarazzi","year":"2018","journal-title":"Biometrics"},{"key":"10.1016\/j.brs.2021.11.019_bib53","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.nbd.2019.03.013","article-title":"Beta bursts during continuous movements accompany the velocity decrement in Parkinson's disease patients","volume":"217","author":"Lofredi","year":"2019","journal-title":"Neurobiol Dis"},{"issue":"2","key":"10.1016\/j.brs.2021.11.019_bib74","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1093\/brain\/awaa400","article-title":"Spatiotemporal features of \u03b2-\u03b3 phase-amplitude coupling in Parkinson\u2019s disease derived from scalp EEG","volume":"144","author":"Gong","year":"2021","journal-title":"Brain"},{"issue":"16","key":"10.1016\/j.brs.2021.11.019_bib54","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.1016\/j.cub.2018.07.009","article-title":"Phase-locked stimulation during cortical beta oscillations produces bidirectional synaptic plasticity in awake monkeys","volume":"28","author":"Zanos","year":"2018","journal-title":"Curr Biol"},{"key":"10.1016\/j.brs.2021.11.019_bib55","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1146\/annurev.neuro.051508.135603","article-title":"Neuronal gamma-band synchronization as a fundamental process in cortical computation","volume":"32","author":"Fries","year":"2009","journal-title":"Annu Rev Neurosci"},{"issue":"2","key":"10.1016\/j.brs.2021.11.019_bib56","doi-asserted-by":"crossref","DOI":"10.1038\/nrn2979","article-title":"Th e role of phase synchronization in memory processes","volume":"12","author":"Fell","year":"2011","journal-title":"Nat Rev Neurosci"},{"issue":"5","key":"10.1016\/j.brs.2021.11.019_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2008.03.014","article-title":"What does phase information of oscillatory brain activity tell us about cognitive processes?","volume":"32","author":"Sauseng","year":"2008","journal-title":"Neurosci Biobehav Rev"},{"issue":"3","key":"10.1016\/j.brs.2021.11.019_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2009.12.040","article-title":"Understanding the relationships between spike rate and delta\/gamma frequency bands of LFPs and EEGs using a local cortical network model","volume":"52","author":"Mazzoni","year":"2010","journal-title":"Neuroimage"},{"issue":"12","key":"10.1016\/j.brs.2021.11.019_bib75","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1113\/jphysiol.2009.185975","article-title":"Differences in subthreshold resonance of hippocampal pyramidal cells and interneurons: the role of h-current and passive membrane characteristics","volume":"588","author":"Zemankovics","year":"2010","journal-title":"J\u00a0Physiol"},{"key":"10.1016\/j.brs.2021.11.019_bib59","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/nn891","article-title":"Pharmacological upregulation of h channels reduces the excitability of pyramidal neuron dendrites","volume":"5","author":"Poolos","year":"2002","journal-title":"Nat Neurosci"},{"issue":"10","key":"10.1016\/j.brs.2021.11.019_bib60","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0076285","article-title":"I\u00a0h tunes theta\/gamma oscillations and cross-frequency coupling in an in silico CA3 model","volume":"8","author":"Neymotin","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.brs.2021.11.019_bib61","doi-asserted-by":"crossref","first-page":"3062","DOI":"10.1093\/brain\/awt239","article-title":"Phase dependent modulation of tremor amplitude in essential tremor through thalamic stimulation","volume":"136","author":"Cagnan","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.brs.2021.11.019_bib62","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1093\/brain\/awv093","article-title":"The relative phases of basal ganglia activities dynamically shape effective connectivity in Parkinson's disease","volume":"138","author":"Cagnan","year":"2015","journal-title":"Brain"},{"key":"10.1016\/j.brs.2021.11.019_bib63","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.conb.2014.08.002","article-title":"Untangling cross-frequency coupling in neuroscience","volume":"31","author":"Aru","year":"2015","journal-title":"Curr Opin Neurobiol"}],"container-title":["Brain Stimulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X21008342?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X21008342?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T14:22:13Z","timestamp":1761834133000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1935861X21008342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":68,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S1935861X21008342"],"URL":"https:\/\/doi.org\/10.1016\/j.brs.2021.11.019","relation":{},"ISSN":["1935-861X"],"issn-type":[{"value":"1935-861X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phase- targeted stimulation modulates phase-amplitude coupling in the motor cortex of the human brain","name":"articletitle","label":"Article Title"},{"value":"Brain Stimulation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brs.2021.11.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}