{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T09:55:26Z","timestamp":1781258126448,"version":"3.54.1"},"reference-count":85,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T00:00:00Z","timestamp":1675382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P41-EB015894"],"award-info":[{"award-number":["P41-EB015894"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01-NS081118"],"award-info":[{"award-number":["R01-NS081118"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["brainstimjrnl.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain Stimulation"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.brs.2023.02.002","type":"journal-article","created":{"date-parts":[[2023,2,4]],"date-time":"2023-02-04T11:47:49Z","timestamp":1675511269000},"page":"445-455","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Lateral cerebellothalamic tract activation underlies DBS therapy for Essential Tremor"],"prefix":"10.1016","volume":"16","author":[{"given":"AnneMarie","family":"Brinda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia P.","family":"Slopsema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca D.","family":"Butler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salman","family":"Ikramuddin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Beall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cong","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Remi","family":"Patriat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Braun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojgan","family":"Goftari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara","family":"Palnitkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Aman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Schrock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott E.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerrold L.","family":"Vitek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noam","family":"Harel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9686-5540","authenticated-orcid":false,"given":"Matthew D.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brs.2023.02.002_bib1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/0140-6736(91)91175-T","article-title":"Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus","volume":"337","author":"Benabid","year":"1991","journal-title":"Lancet"},{"key":"10.1016\/j.brs.2023.02.002_bib2","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1080\/02688690701552278","article-title":"Thalamic deep brain stimulation in the treatment of essential tremor: a long-term follow-up","volume":"21","author":"Blomstedt","year":"2007","journal-title":"Br J Neurosurg"},{"key":"10.1016\/j.brs.2023.02.002_bib3","first-page":"1669","article-title":"Microelectrode recording findings within the tractography-defined ventral intermediate nucleus","volume":"126","author":"King","year":"2017","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.brs.2023.02.002_bib4","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1227\/00006123-199412000-00016","article-title":"Bilateral chronic electrostimulation of ventroposterolateral pallidum: a new therapeutic approach for alleviating all parkinsonian symptoms","volume":"35","author":"Siegfried","year":"1994","journal-title":"Neurosurgery"},{"key":"10.1016\/j.brs.2023.02.002_bib5","first-page":"640","article-title":"Factors involved in long-term efficacy of deep brain stimulation of the thalamus for essential tremor: clinical article","volume":"109","author":"Pilitsis","year":"2008","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.brs.2023.02.002_bib6","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1001\/archneur.62.8.noc40425","article-title":"Management of referred deep brain stimulation failures: a retrospective analysis from 2 movement disorders centers","volume":"62","author":"Okun","year":"2005","journal-title":"Arch Neurol"},{"key":"10.1016\/j.brs.2023.02.002_bib7","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1227\/01.NEU.0000119329.66931.9E","article-title":"Thalamic deep brain stimulation for essential tremor: relation of lead location to outcome","volume":"54","author":"Papavassiliou","year":"2004","journal-title":"Neurosurgery"},{"key":"10.1016\/j.brs.2023.02.002_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.clineuro.2019.105466","article-title":"Comparison of posterior subthalamic area deep brain stimulation for tremor using conventional landmarks versus directly targeting the dentatorubrothalamic tract with tractography","volume":"185","author":"Low","year":"2019","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1016\/j.brs.2023.02.002_bib9","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1212\/01.WNL.0000044156.56643.74","article-title":"Tremor response to polarity, voltage, pulsewidth and frequency of thalamic stimulation","volume":"60","author":"O'Suilleabhain","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.brs.2023.02.002_bib10","doi-asserted-by":"crossref","first-page":"843","DOI":"10.3389\/fneur.2021.678592","article-title":"Stimulation-induced side effects of deep brain stimulation in the ventralis intermedius and posterior subthalamic area for essential tremor","volume":"12","author":"Kim","year":"2021","journal-title":"Front Neurol"},{"key":"10.1016\/j.brs.2023.02.002_bib11","article-title":"Model-based comparison of deep brain stimulation array functionality with varying number of radial electrodes and machine learning feature sets","volume":"58","author":"Teplitzky","year":"2016","journal-title":"Front Comput Neurosci"},{"key":"10.1016\/j.brs.2023.02.002_bib12","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2552\/aad978","article-title":"Clinical deep brain stimulation strategies for orientation-selective pathway activation","volume":"15","author":"Slopsema","year":"2018","journal-title":"J\u00a0Neural Eng"},{"key":"10.1016\/j.brs.2023.02.002_bib13","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1093\/brain\/awu102","article-title":"Directional deep brain stimulation: an intraoperative double-blind pilot study","volume":"137","author":"Pollo","year":"2014","journal-title":"Brain"},{"key":"10.1016\/j.brs.2023.02.002_bib14","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.brs.2017.12.015","article-title":"Thalamic directional deep brain stimulation for tremor: spend less, get more","volume":"11","author":"Rebelo","year":"2018","journal-title":"Brain Stimul"},{"key":"10.1016\/j.brs.2023.02.002_bib15","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1111\/ner.13234","article-title":"Directional deep brain stimulation of the thalamic ventral intermediate area for essential tremor increases therapeutic window","volume":"24","author":"Bruno","year":"2021","journal-title":"Neuromodulation Technol Neural Interface"},{"key":"10.1016\/j.brs.2023.02.002_bib16","first-page":"344","article-title":"Combined (thalamotomy and stimulation) stereotactic surgery of the VIM thalamic nucleus for bilateral Parkinson disease","volume":"50","author":"Benabid","year":"1987","journal-title":"Appl Neurophysiol"},{"key":"10.1016\/j.brs.2023.02.002_bib17","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/mdc3.12565","article-title":"Ventral intermediate nucleus versus zona incerta region deep brain stimulation in essential tremor","volume":"5","author":"Eisinger","year":"2018","journal-title":"Mov Disord Clin Pract"},{"key":"10.1016\/j.brs.2023.02.002_bib18","doi-asserted-by":"crossref","first-page":"3086","DOI":"10.1093\/brain\/awz236","article-title":"Connectivity profile of thalamic deep brain stimulation to effectively treat essential tremor","volume":"142","author":"Al-Fatly","year":"2019","journal-title":"Brain"},{"key":"10.1016\/j.brs.2023.02.002_bib19","first-page":"434","article-title":"Deep brain stimulation in the nucleus ventralis intermedius in patients with essential tremor: habituation of tremor suppression","volume":"258","author":"Barbe","year":"2011","journal-title":"J\u00a0Neurol"},{"key":"10.1016\/j.brs.2023.02.002_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.bandl.2019.104724","article-title":"The effects of thalamic and posterior subthalamic deep brain stimulation on speech in patients with essential tremor \u2013 a prospective, randomized, doubleblind crossover study","volume":"202","author":"Becker","year":"2020","journal-title":"Brain Lang"},{"key":"10.1016\/j.brs.2023.02.002_bib21","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1007\/s00701-007-1230-1","article-title":"Deep brain stimulation in the subthalamic area is more effective than nucleus ventralis intermedius stimulation for bilateral intention tremor","volume":"149","author":"Hamel","year":"2007","journal-title":"Acta Neurochir"},{"key":"10.1016\/j.brs.2023.02.002_bib22","article-title":"The dentato-rubro-thalamic tract as the potential common deep brain stimulation target for tremor of various origin: an observational case series","author":"Coenen","year":"2020","journal-title":"Acta Neurochir"},{"key":"10.1016\/j.brs.2023.02.002_bib23","doi-asserted-by":"crossref","first-page":"e89","DOI":"10.1016\/j.wneu.2020.01.039","article-title":"Thalamic deep brain stimulation for essential tremor: relation of the dentatorubrothalamic tract with stimulation parameters","volume":"137","author":"Yang","year":"2020","journal-title":"World Neurosurg"},{"key":"10.1016\/j.brs.2023.02.002_bib24","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/ner.12238","article-title":"Deep brain stimulation for essential tremor: targeting the dentato-rubro-thalamic tract?","volume":"18","author":"Schlaier","year":"2015","journal-title":"Neuromodulation Technol Neural Interface"},{"key":"10.1016\/j.brs.2023.02.002_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2021.102846","article-title":"Connectivity correlates to predict essential tremor deep brain stimulation outcome: evidence for a common treatment pathway","volume":"32","author":"Middlebrooks","year":"2021","journal-title":"NeuroImage Clin"},{"key":"10.1016\/j.brs.2023.02.002_bib26","doi-asserted-by":"crossref","DOI":"10.1093\/ons\/opab324","article-title":"Evaluating and optimizing dentato-rubro-thalamic-tract deterministic tractography in deep brain stimulation for essential tremor","author":"Bot","year":"2021","journal-title":"Oper Neurosurg"},{"key":"10.1016\/j.brs.2023.02.002_bib27","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1159\/000314357","article-title":"Patient-specific model-based investigation of speech intelligibility and movement during deep brain stimulation","volume":"88","author":"\u00c5str\u00f6m","year":"2010","journal-title":"Stereotact Funct Neurosurg"},{"key":"10.1016\/j.brs.2023.02.002_bib28","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/ana.25958","article-title":"Network fingerprint of stimulation-induced speech impairment in essential tremor","volume":"89","author":"Petry-Schmelzer","year":"2021","journal-title":"Ann Neurol"},{"key":"10.1016\/j.brs.2023.02.002_bib29","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.1093\/brain\/aww223","article-title":"Progressive gait ataxia following deep brain stimulation for essential tremor: adverse effect or lack of efficacy?","volume":"139","author":"Reich","year":"2016","journal-title":"Brain"},{"key":"10.1016\/j.brs.2023.02.002_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2020.102486","article-title":"Structure-function relationship of the posterior subthalamic area with directional deep brain stimulation for essential tremor","volume":"28","author":"L\u00e9vy","year":"2020","journal-title":"NeuroImage Clin"},{"key":"10.1016\/j.brs.2023.02.002_bib31","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2560\/9\/4\/046005","article-title":"Improved spatial targeting with directionally segmented deep brain stimulation leads for treating essential tremor","volume":"9","author":"Keane","year":"2012","journal-title":"J\u00a0Neural Eng"},{"key":"10.1016\/j.brs.2023.02.002_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0176132","article-title":"Creating and parameterizing patient-specific deep brain stimulation pathway-activation models using the hyperdirect pathway as an example","volume":"12","author":"Gunalan","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.brs.2023.02.002_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2019.102026","article-title":"White matter tracing combined with electric field simulation \u2013 a patient-specific approach for deep brain stimulation","volume":"24","author":"Nordin","year":"2019","journal-title":"NeuroImage Clin"},{"key":"10.1016\/j.brs.2023.02.002_bib34","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.neuroimage.2018.01.015","article-title":"Quantifying axonal responses in patient-specific models of subthalamic deep brain stimulation","volume":"172","author":"Gunalan","year":"2018","journal-title":"Neuroimage"},{"key":"10.1016\/j.brs.2023.02.002_bib35","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2552\/aae12f","article-title":"Multi-objective particle swarm optimization for postoperative deep brain stimulation targeting of subthalamic nucleus pathways","volume":"15","author":"Pe\u00f1a","year":"2018","journal-title":"J\u00a0Neural Eng"},{"key":"10.1016\/j.brs.2023.02.002_bib36","first-page":"1821","article-title":"Pallidothalamic tract activation predicts suppression of stimulation-induced dyskinesias in a case study of Parkinson's disease","volume":"13","author":"Goftari","year":"2020","journal-title":"Brain Stimul Basic Transl Clin Res Neuromodulation"},{"key":"10.1016\/j.brs.2023.02.002_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0201469","article-title":"Patient-specific anatomical model for deep brain stimulation based on 7 Tesla MRI","volume":"13","author":"Duchin","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.brs.2023.02.002_bib38","article-title":"Individualized parcellation of the subthalamic nucleus in patients with Parkinson's disease with 7T MRI","author":"Plantinga","year":"2016","journal-title":"Neuroimage"},{"key":"10.1016\/j.brs.2023.02.002_bib39","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.mri.2012.05.001","article-title":"3D slicer as an image computing platform for the quantitative imaging network","volume":"30","author":"Fedorov","year":"2012","journal-title":"Magn Reson Imaging"},{"key":"10.1016\/j.brs.2023.02.002_bib40","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.neuroimage.2011.09.015","volume":"62","author":"Jenkinson","year":"2012","journal-title":"FSL. NeuroImage"},{"key":"10.1016\/j.brs.2023.02.002_bib41","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.neuroimage.2010.02.014","article-title":"Influence of anisotropic electrical conductivity in white matter tissue on the EEG\/MEG forward and inverse solution. A high-resolution whole head simulation study","volume":"51","author":"G\u00fcllmar","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.brs.2023.02.002_bib42","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1109\/TBME.2012.2189885","article-title":"Modeling the field distribution in deep brain stimulation: the influence of anisotropy of brain tissue","volume":"59","author":"Schmidt","year":"2012","journal-title":"IEEE Trans Biomed Eng"},{"key":"10.1016\/j.brs.2023.02.002_bib43","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1088\/0031-9155\/41\/11\/001","article-title":"The dielectric properties of biological tissues .1. Literature survey","volume":"41","author":"Gabriel","year":"1996","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.brs.2023.02.002_bib44","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1088\/0031-9155\/41\/11\/002","article-title":"The dielectric properties of biological tissues: II. Measurements in the frequency range 10 Hz to 20 GHz","volume":"41","author":"Gabriel","year":"1996","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.brs.2023.02.002_bib45","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1088\/0031-9155\/41\/11\/003","article-title":"The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissues","volume":"41","author":"Gabriel","year":"1996","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.brs.2023.02.002_bib46","first-page":"341","article-title":"Dispersion and absorption in dielectrics I. Alternating current characteristics","volume":"9","author":"Cole","year":"1941","journal-title":"J\u00a0Chem Phys"},{"key":"10.1016\/j.brs.2023.02.002_bib47","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.brs.2016.09.001","article-title":"Role of soft-tissue heterogeneity in computational models of deep brain stimulation","volume":"10","author":"Howell","year":"2017","journal-title":"Brain Stimul"},{"key":"10.1016\/j.brs.2023.02.002_bib48","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.brainresbull.2007.07.007","article-title":"The peri-electrode space is a significant element of the electrode\u2013brain interface in deep brain stimulation: a computational study","volume":"74","author":"Yousif","year":"2007","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.brs.2023.02.002_bib49","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1227\/NEU.0b013e3181f74105","article-title":"An assessment of current brain targets for deep brain stimulation surgery with susceptibility-weighted imaging at 7 tesla","volume":"67","author":"Abosch","year":"2010","journal-title":"Neurosurgery"},{"key":"10.1016\/j.brs.2023.02.002_bib50","article-title":"Multimodal 7T imaging of thalamic nuclei for preclinical deep brain stimulation applications","volume":"264","author":"Xiao","year":"2016","journal-title":"Brain Imaging Methods"},{"key":"10.1016\/j.brs.2023.02.002_bib51","series-title":"Atlas of the human brain","author":"Mai","year":"2007"},{"key":"10.1016\/j.brs.2023.02.002_bib52","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/cercor\/bhg087","article-title":"Automatically parcellating the human cerebral cortex","volume":"14","author":"Fischl","year":"2004","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.brs.2023.02.002_bib53","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S1361-8415(01)00036-6","article-title":"A\u00a0global optimisation method for robust affine registration of brain images","volume":"5","author":"Jenkinson","year":"2001","journal-title":"Med Image Anal"},{"key":"10.1016\/j.brs.2023.02.002_bib54","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/nn1075","article-title":"Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging","volume":"6","author":"Behrens","year":"2003","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.brs.2023.02.002_bib55","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1002\/mrm.10609","article-title":"Characterization and propagation of uncertainty in diffusion-weighted MR imaging","volume":"50","author":"Behrens","year":"2003","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.brs.2023.02.002_bib56","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1523\/JNEUROSCI.3768-06.2007","article-title":"Cortical control of zona incerta","volume":"27","author":"Barth\u00f3","year":"2007","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.brs.2023.02.002_bib57","author":"Haber"},{"key":"10.1016\/j.brs.2023.02.002_bib58","doi-asserted-by":"crossref","first-page":"e630","DOI":"10.1016\/j.wneu.2017.10.042","article-title":"Superselective thalamotomy in the most lateral part of the ventralis intermedius nucleus for controlling essential and parkinsonian tremor","volume":"109","author":"Hirato","year":"2018","journal-title":"World Neurosurg"},{"key":"10.1016\/j.brs.2023.02.002_bib59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-0173(89)90007-6","article-title":"A\u00a0new parcellation of the human thalamus on the basis of histochemical staining","volume":"14","author":"Hirai","year":"1989","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.brs.2023.02.002_bib60","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/cne.901950105","article-title":"Projections of the cerebellar and dorsal column nuclei upon the thalamus of the rhesus monkey","volume":"195","author":"Kalil","year":"1981","journal-title":"J\u00a0Comp Neurol"},{"key":"10.1016\/j.brs.2023.02.002_bib61","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1152\/jn.00989.2003","article-title":"Cellular effects of deep brain stimulation: model-based analysis of activation and inhibition","volume":"91","author":"McIntyre","year":"2004","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.brs.2023.02.002_bib62","author":"Goftari"},{"key":"10.1016\/j.brs.2023.02.002_bib63","series-title":"The NEURON book","author":"Carnevale","year":"2006"},{"key":"10.1016\/j.brs.2023.02.002_bib64","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.brs.2010.01.003","article-title":"Patient-specific models of deep brain stimulation: influence of field model complexity on neural activation predictions","volume":"3","author":"Chaturvedi","year":"2010","journal-title":"Brain Stimul"},{"key":"10.1016\/j.brs.2023.02.002_bib65","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1152\/jn.00039.2012","article-title":"Neural targets for relieving parkinsonian rigidity and bradykinesia with pallidal deep brain stimulation","volume":"108","author":"Johnson","year":"2012","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.brs.2023.02.002_bib66","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1159\/000448926","article-title":"Deep brain stimulation of the caudal zona incerta: tremor control in relation to the location of stimulation fields","volume":"94","author":"Fytagoridis","year":"2016","journal-title":"Stereotact Funct Neurosurg"},{"key":"10.1016\/j.brs.2023.02.002_bib67","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1212\/WNL.0000000000000127","article-title":"Individualized current-shaping reduces DBS-induced dysarthria in patients with essential tremor","volume":"82","author":"Barbe","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.brs.2023.02.002_bib68","doi-asserted-by":"crossref","DOI":"10.3389\/fnint.2012.00015","article-title":"Connectomic surgery\u201d: diffusion tensor imaging (DTI) tractography as a targeting modality for surgical modulation of neural networks","volume":"6","author":"Henderson","year":"2012","journal-title":"Front Integr Neurosci"},{"key":"10.1016\/j.brs.2023.02.002_bib69","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00234-017-1972-2","article-title":"A\u00a0method for pre-operative single-subject thalamic segmentation based on probabilistic tractography for essential tremor deep brain stimulation","volume":"60","author":"Middlebrooks","year":"2018","journal-title":"Neuroradiology"},{"key":"10.1016\/j.brs.2023.02.002_bib70","article-title":"Directed stimulation of the dentato-rubro-thalamic tract for deep brain stimulation in essential tremor: a blinded clinical trial","author":"Middlebrooks","year":"2021","journal-title":"NeuroRadiol J"},{"key":"10.1016\/j.brs.2023.02.002_bib71","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1152\/jn.1994.71.4.1498","article-title":"Physiologic properties and somatotopic organization of the primate motor thalamus","volume":"71","author":"Vitek","year":"1994","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.brs.2023.02.002_bib72","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1016\/j.clinph.2008.02.025","article-title":"A\u00a0method to estimate the spatial extent of activation in thalamic deep brain stimulation","volume":"119","author":"Kuncel","year":"2008","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.brs.2023.02.002_bib73","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1097\/00004691-200011000-00003","article-title":"Microelectrode studies of normal organization and plasticity of human somatosensory thalamus","volume":"17","author":"Hua","year":"2000","journal-title":"J\u00a0Clin Neurophysiol"},{"key":"10.1016\/j.brs.2023.02.002_bib74","doi-asserted-by":"crossref","first-page":"3094","DOI":"10.1152\/jn.00881.2004","article-title":"Differences in neuronal firing rates in pallidal and cerebellar receiving areas of thalamus in patients with Parkinson's disease, essential tremor, and pain","volume":"93","author":"Molnar","year":"2005","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.brs.2023.02.002_bib75","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1002\/mds.23195","article-title":"Deep brain stimulation for essential tremor: a systematic review","volume":"25","author":"Flora","year":"2010","journal-title":"Mov Disord"},{"key":"10.1016\/j.brs.2023.02.002_bib76","first-page":"506","article-title":"Long-term evaluation of deep brain stimulation of the thalamus","volume":"104","author":"Pahwa","year":"2006","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.brs.2023.02.002_bib77","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.parkreldis.2016.08.017","article-title":"Precise stimulation location optimizes speech outcomes in essential tremor","volume":"32","author":"Matsumoto","year":"2016","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.brs.2023.02.002_bib78","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0165-0173(83)90016-4","article-title":"Anatomical evidence for segregated focal groupings of efferent cells and their terminal ramifications in the cerebellothalamic pathway of the monkey","volume":"286","author":"Asanuma","year":"1983","journal-title":"Brain Res"},{"key":"10.1016\/j.brs.2023.02.002_bib79","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/cne.1277","article-title":"Thalamic terminal morphology and distribution of single corticothalamic axons originating from layers 5 and 6 of the cat motor cortex","volume":"437","author":"Kakei","year":"2001","journal-title":"J\u00a0Comp Neurol"},{"key":"10.1016\/j.brs.2023.02.002_bib80","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/cne.10539","article-title":"Reevaluation of the primary motor cortex connections with the thalamus in primates","volume":"457","author":"Kultas-Ilinsky","year":"2003","journal-title":"J\u00a0Comp Neurol"},{"key":"10.1016\/j.brs.2023.02.002_bib81","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1152\/jn.00906.2010","article-title":"Stimulus features underlying reduced tremor suppression with temporally patterned deep brain stimulation","volume":"107","author":"Birdno","year":"2011","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.brs.2023.02.002_bib82","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s00429-007-0170-0","article-title":"Human pallidothalamic and cerebellothalamic tracts: anatomical basis for functional stereotactic neurosurgery","volume":"212","author":"Gallay","year":"2008","journal-title":"Brain Struct Funct"},{"key":"10.1016\/j.brs.2023.02.002_bib83","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1002\/mds.870120517","article-title":"Inhibition of voluntary activity by thalamic stimulation in humans: relevance for the control of tremor","volume":"12","author":"Strafella","year":"1997","journal-title":"Mov Disord"},{"key":"10.1016\/j.brs.2023.02.002_bib84","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1093\/cercor\/bhn231","article-title":"Two types of thalamocortical projections from the motor thalamic nuclei of the rat: a single neuron-tracing study using viral vectors","volume":"19","author":"Kuramoto","year":"2009","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.brs.2023.02.002_bib85","first-page":"95","article-title":"The anatomy of the caudal zona incerta in rodents and primates","volume":"224","author":"Watson","year":"2014","journal-title":"J\u00a0Anat"}],"container-title":["Brain Stimulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X23016844?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1935861X23016844?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T14:24:04Z","timestamp":1761834244000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1935861X23016844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":85,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S1935861X23016844"],"URL":"https:\/\/doi.org\/10.1016\/j.brs.2023.02.002","relation":{},"ISSN":["1935-861X"],"issn-type":[{"value":"1935-861X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lateral cerebellothalamic tract activation underlies DBS therapy for Essential Tremor","name":"articletitle","label":"Article Title"},{"value":"Brain Stimulation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brs.2023.02.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}